DK0646012T3 - Sårheling og behandling af fibrotiske sygdomme ved hjælp af TGFbeta-3 - Google Patents
Sårheling og behandling af fibrotiske sygdomme ved hjælp af TGFbeta-3Info
- Publication number
- DK0646012T3 DK0646012T3 DK93906723T DK93906723T DK0646012T3 DK 0646012 T3 DK0646012 T3 DK 0646012T3 DK 93906723 T DK93906723 T DK 93906723T DK 93906723 T DK93906723 T DK 93906723T DK 0646012 T3 DK0646012 T3 DK 0646012T3
- Authority
- DK
- Denmark
- Prior art keywords
- tgfbeta
- treatment
- wound healing
- fibrotic diseases
- composition
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 230000003176 fibrotic effect Effects 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 2
- 230000029663 wound healing Effects 0.000 title 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929206861A GB9206861D0 (en) | 1992-03-28 | 1992-03-28 | Wound healing and treatment of fibrotic disorders |
| PCT/GB1993/000586 WO1993019769A1 (en) | 1992-03-28 | 1993-03-22 | Wound healing and treatment of fibrotic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0646012T3 true DK0646012T3 (da) | 2003-03-03 |
Family
ID=10713078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93906723T DK0646012T3 (da) | 1992-03-28 | 1993-03-22 | Sårheling og behandling af fibrotiske sygdomme ved hjælp af TGFbeta-3 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6331298B1 (da) |
| EP (1) | EP0646012B1 (da) |
| JP (2) | JP3919212B2 (da) |
| AT (1) | ATE230605T1 (da) |
| AU (1) | AU673161B2 (da) |
| BR (1) | BR9306226A (da) |
| CA (1) | CA2131383C (da) |
| CZ (1) | CZ236694A3 (da) |
| DE (1) | DE69332624T2 (da) |
| DK (1) | DK0646012T3 (da) |
| ES (1) | ES2189790T3 (da) |
| GB (1) | GB9206861D0 (da) |
| HU (1) | HUT68905A (da) |
| NO (1) | NO943466L (da) |
| NZ (1) | NZ249937A (da) |
| PT (1) | PT646012E (da) |
| RU (1) | RU94042387A (da) |
| SK (1) | SK116894A3 (da) |
| WO (1) | WO1993019769A1 (da) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9106678D0 (en) * | 1991-03-28 | 1991-05-15 | Ferguson Mark W J | Wound healing |
| US7384634B2 (en) * | 1991-08-30 | 2008-06-10 | University Of South Florida | Connective tissue growth factor |
| US6395494B1 (en) | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
| US5449671A (en) * | 1993-09-29 | 1995-09-12 | Alcon Laboratories, Inc. | Use of TGF-β3, to prevent or retard fistula closure following glaucoma filtration surgery |
| EP0670733A1 (en) * | 1993-09-29 | 1995-09-13 | Alcon Laboratories, Inc. | Compositions containing growth factors and antiplastic agents |
| US5411940A (en) * | 1993-09-29 | 1995-05-02 | Alcon Laboratories, Inc. | Use of TGF-β3 to reduce the formation of scar tissue in response to corneal trauma |
| JP4083794B2 (ja) * | 1994-03-29 | 2008-04-30 | レノボ・リミテッド | 創傷の治癒 |
| GB2288118A (en) * | 1994-03-29 | 1995-10-11 | Univ Manchester | Wound healing composition |
| US5621093A (en) * | 1995-06-06 | 1997-04-15 | Anika Research, Inc. | Steam-sterilizing solid hyaluronic acid |
| GB2304045A (en) * | 1995-08-04 | 1997-03-12 | Univ Manchester | Betaglycan compositions for promoting the healing of wounds and fibrotic diseases |
| GB2304047A (en) * | 1995-08-09 | 1997-03-12 | Univ Manchester | Pharmaceutical compositions containing cytokines |
| GB2306481A (en) * | 1995-10-21 | 1997-05-07 | Univ Manchester | Pharmaceutical comprising a stimulator of activin and/or inhibin |
| EP0941108B1 (en) * | 1996-12-04 | 2002-10-16 | Renovo Limited | Wound healing and treatment of fibrosis |
| WO1998046588A2 (en) | 1997-04-11 | 1998-10-22 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
| US6613083B2 (en) | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
| CA2561686C (en) | 2004-03-31 | 2014-12-02 | Genentech, Inc. | Humanized anti-tgf-beta antibodies |
| US8017395B2 (en) | 2004-12-17 | 2011-09-13 | Lifescan, Inc. | Seeding cells on porous supports |
| AU2006202209B2 (en) | 2005-05-27 | 2011-04-14 | Lifescan, Inc. | Amniotic fluid derived cells |
| EP1888123B1 (en) * | 2005-06-08 | 2013-01-09 | Janssen Biotech, Inc. | A cellular therapy for ocular degeneration |
| GB0514262D0 (en) * | 2005-07-12 | 2005-08-17 | Renovo Ltd | Promotion of epithelial regeneration |
| US20070122448A1 (en) * | 2005-11-28 | 2007-05-31 | Alireza Rezania | Compositions and methods to create a vascularized environment for cellular transplantation |
| GB0604966D0 (en) * | 2006-03-11 | 2006-04-19 | Renovo Ltd | Medicaments and proteins |
| GB0604938D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Proteins, nucleic acids and medicaments |
| GB0604964D0 (en) * | 2006-03-11 | 2006-04-19 | Renovo Ltd | Protein folding |
| WO2007127927A2 (en) | 2006-04-28 | 2007-11-08 | Lifescan, Inc. | Differentiation of human embryonic stem cells |
| US8741643B2 (en) | 2006-04-28 | 2014-06-03 | Lifescan, Inc. | Differentiation of pluripotent stem cells to definitive endoderm lineage |
| GB0617816D0 (en) * | 2006-09-11 | 2006-10-18 | Renovo Ltd | Nucleic acids and methods of protein expression |
| JP5960944B2 (ja) | 2006-11-15 | 2016-08-02 | コーダ セラピューティクス, インコーポレイテッド | 創傷治癒のための改善された方法および組成物 |
| WO2008094597A2 (en) * | 2007-01-30 | 2008-08-07 | University Of Georgia Research Foundation, Inc. | Early mesoderm cells, a stable population of mesendoderm cells that has utility for generation of endoderm and mesoderm lineages and multipotent migratory cells (mmc) |
| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| EP2559756B1 (en) | 2007-07-01 | 2019-12-18 | Janssen Biotech, Inc. | Single pluripotent stem cell culture |
| AU2008273813B2 (en) * | 2007-07-12 | 2013-06-13 | Compugen Ltd. | Bioactive peptides and method of using same |
| ES2537578T3 (es) | 2007-07-18 | 2015-06-09 | Lifescan, Inc. | Diferenciación de las células madre de embriones humanos |
| US9096832B2 (en) | 2007-07-31 | 2015-08-04 | Lifescan, Inc. | Differentiation of human embryonic stem cells |
| ATE523585T1 (de) | 2007-11-27 | 2011-09-15 | Lifescan Inc | Differenzierung menschlicher embryonaler stammzellen |
| EP2234656A2 (en) | 2007-12-21 | 2010-10-06 | Coda Therapeutics, Inc. | Improved medical devices |
| JP2011507856A (ja) * | 2007-12-21 | 2011-03-10 | コーダ セラピューティクス, インコーポレイテッド | 整形外科状態の治療のための抗コネキシンポリヌクレオチド、ペプチド、または抗体の使用 |
| JP2011507862A (ja) * | 2007-12-21 | 2011-03-10 | コーダ セラピューティクス, インコーポレイテッド | 異常瘢痕または過剰瘢痕の治療のための抗コネキシン43ポリヌクレオチドの使用 |
| CA2959401C (en) | 2008-02-21 | 2021-12-07 | Centocor Ortho Biotech Inc. | Methods, surface modified plates and compositions for cell attachment, cultivation and detachment |
| US8623648B2 (en) | 2008-04-24 | 2014-01-07 | Janssen Biotech, Inc. | Treatment of pluripotent cells |
| KR101651661B1 (ko) | 2008-06-30 | 2016-08-26 | 얀센 바이오테크 인코포레이티드 | 만능 줄기 세포의 분화 |
| PL2296598T3 (pl) * | 2008-07-07 | 2015-06-30 | Laboratoire Medidom S A | Redukujący temperaturę opatrunek do gojenia ran |
| US20110305672A1 (en) | 2008-07-25 | 2011-12-15 | University Of Georgia Research Foundation, Inc. | COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME |
| CA2731821A1 (en) | 2008-07-25 | 2010-01-28 | Stephen Dalton | Compositions for mesoderm derived isl1+ multipotent cells (imps), epicardial progenitor cells (epcs) and multipotent cxcr4+cd56+ cells (c56cs) and methods of use |
| US20100028307A1 (en) * | 2008-07-31 | 2010-02-04 | O'neil John J | Pluripotent stem cell differentiation |
| MX2011004563A (es) * | 2008-10-31 | 2011-06-01 | Centocor Ortho Biotech Inc | Diferenciacion de celulas madre embrionarias humanas al linaje endocrino pancreatico. |
| CN102272291B (zh) | 2008-10-31 | 2018-01-16 | 詹森生物科技公司 | 人胚胎干细胞向胰腺内分泌谱系的分化 |
| PL2366022T3 (pl) * | 2008-11-20 | 2016-11-30 | Sposoby i kompozycje do przyłączania i hodowli komórek na podłożach planarnych | |
| PL2366021T3 (pl) | 2008-11-20 | 2017-12-29 | Janssen Biotech, Inc. | Hodowla pluripotencjalnych komórek macierzystych na mikronośnikach |
| ES2693088T3 (es) * | 2009-07-20 | 2018-12-07 | Janssen Biotech, Inc. | Diferenciación de células madre embriónicas humanas |
| KR20170118969A (ko) | 2009-07-20 | 2017-10-25 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
| AU2010276402B2 (en) * | 2009-07-20 | 2014-07-03 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| CN102695790A (zh) * | 2009-10-29 | 2012-09-26 | 詹森生物科技公司 | 多能干细胞 |
| DE202009017772U1 (de) * | 2009-12-10 | 2011-04-21 | Orthogen Ag | Kombinationspräparate mit Cytokin-Antagonist und Corticosteroid |
| AU2010333839C1 (en) | 2009-12-23 | 2016-07-21 | Janssen Biotech Inc. | Differentiation of human embryonic stem cells |
| MX339669B (es) | 2009-12-23 | 2016-06-02 | Janssen Biotech Inc | Diferenciacion de celulas madres embrionarias humanas. |
| CN107189979B (zh) * | 2010-03-01 | 2021-05-04 | 詹森生物科技公司 | 纯化衍生自多能干细胞的细胞的方法 |
| KR101986176B1 (ko) | 2010-05-12 | 2019-06-05 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
| DK2603226T3 (da) | 2010-08-12 | 2021-06-07 | Janssen Biotech Inc | Behandling af diabetes med endokrine pankreas-prækursorceller |
| WO2012030539A2 (en) | 2010-08-31 | 2012-03-08 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| AU2011296381B2 (en) | 2010-08-31 | 2016-03-31 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| WO2012030540A2 (en) | 2010-08-31 | 2012-03-08 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
| WO2012081029A1 (en) | 2010-12-15 | 2012-06-21 | Kadimastem Ltd. | Insulin producing cells derived from pluripotent stem cells |
| US9388386B2 (en) | 2011-12-22 | 2016-07-12 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into single hormonal insulin positive cells |
| CA2866590A1 (en) | 2012-03-07 | 2013-09-12 | Janssen Biotech, Inc. | Defined media for expansion and maintenance of pluripotent stem cells |
| WO2013184888A1 (en) | 2012-06-08 | 2013-12-12 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into pancreatic endocrine cells |
| RU2687379C2 (ru) | 2012-12-31 | 2019-05-13 | Янссен Байотек, Инк. | Суспендирование и кластеризация плюрипотентных клеток человека с целью их дифференцировки в панкреатические эндокринные клетки |
| WO2014105543A1 (en) | 2012-12-31 | 2014-07-03 | Janssen Biotech, Inc. | Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells |
| US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
| RU2684215C2 (ru) | 2012-12-31 | 2019-04-04 | Янссен Байотек, Инк. | Способ получения панкреатических эндокринных клеток (варианты) и способ увеличения выхода бета-клеток |
| US12558316B2 (en) | 2013-03-13 | 2026-02-24 | University Of Miami | Methods and compositions for the treatment of epidermolysis bullosa |
| CA2906502A1 (en) | 2013-03-13 | 2014-10-02 | University Of Miami | Method for isolation and purification of microvesicles from cell culture supernatants and biological fluids |
| JP6588969B2 (ja) | 2014-05-16 | 2019-10-09 | ヤンセン バイオテツク,インコーポレーテツド | 膵内分泌細胞内のmafa発現を強化するための小分子の使用 |
| JP6683686B2 (ja) | 2014-08-22 | 2020-04-22 | オークランド ユニサービシーズ リミティド | チャネル調節剤 |
| IL293289B2 (en) | 2015-11-30 | 2024-04-01 | Kadimastem Ltd | Methods for differentiating and purifying pancreatic endocrine cells |
| KR20180107151A (ko) * | 2016-02-17 | 2018-10-01 | 노파르티스 아게 | Tgf베타 2 항체 |
| JP6705911B2 (ja) | 2016-04-14 | 2020-06-03 | ヤンセン バイオテツク,インコーポレーテツド | 多能性幹細胞の中腸内胚葉細胞への分化 |
| JP7531887B2 (ja) * | 2020-07-31 | 2024-08-13 | 学校法人関西医科大学 | TGF-βを含む組織の線維化抑制剤 |
| IL300393A (en) | 2020-08-21 | 2023-04-01 | Univ Miami | Preparations and treatment methods using microvesicles from mesenchymal stem cells derived from bone marrow |
| US20230390341A1 (en) | 2022-04-19 | 2023-12-07 | University Of Miami | Methods and compositions for prevention and treatment of graft versus host disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5155214A (en) * | 1984-03-05 | 1992-10-13 | The Salk Institute For Biological Studies | Basic fibroblast growth factor |
| GB8823649D0 (en) * | 1988-10-07 | 1988-11-16 | Geistlich Soehne Ag | Chemical compounds |
| IE61346B1 (en) | 1988-11-02 | 1994-11-02 | Genentech Inc | A permeable material to fit around the teeth or gums of a mammal |
| GB8927546D0 (en) | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| WO1991010727A1 (en) * | 1990-01-22 | 1991-07-25 | La Jolla Cancer Research Foundation | Inhibitors of cell regulatory factors |
| GB9106678D0 (en) | 1991-03-28 | 1991-05-15 | Ferguson Mark W J | Wound healing |
-
1992
- 1992-03-28 GB GB929206861A patent/GB9206861D0/en active Pending
-
1993
- 1993-03-22 SK SK1168-94A patent/SK116894A3/sk unknown
- 1993-03-22 PT PT93906723T patent/PT646012E/pt unknown
- 1993-03-22 US US08/307,640 patent/US6331298B1/en not_active Expired - Fee Related
- 1993-03-22 HU HU9402771A patent/HUT68905A/hu unknown
- 1993-03-22 EP EP93906723A patent/EP0646012B1/en not_active Expired - Lifetime
- 1993-03-22 CZ CZ942366A patent/CZ236694A3/cs unknown
- 1993-03-22 JP JP51719393A patent/JP3919212B2/ja not_active Expired - Fee Related
- 1993-03-22 WO PCT/GB1993/000586 patent/WO1993019769A1/en not_active Ceased
- 1993-03-22 BR BR9306226A patent/BR9306226A/pt not_active Application Discontinuation
- 1993-03-22 ES ES93906723T patent/ES2189790T3/es not_active Expired - Lifetime
- 1993-03-22 NZ NZ249937A patent/NZ249937A/en not_active IP Right Cessation
- 1993-03-22 RU RU94042387/14A patent/RU94042387A/ru unknown
- 1993-03-22 DE DE69332624T patent/DE69332624T2/de not_active Expired - Lifetime
- 1993-03-22 AU AU37623/93A patent/AU673161B2/en not_active Ceased
- 1993-03-22 DK DK93906723T patent/DK0646012T3/da active
- 1993-03-22 AT AT93906723T patent/ATE230605T1/de not_active IP Right Cessation
- 1993-03-22 CA CA002131383A patent/CA2131383C/en not_active Expired - Lifetime
-
1994
- 1994-09-16 NO NO943466A patent/NO943466L/no unknown
-
2005
- 2005-05-11 JP JP2005138819A patent/JP2005290009A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US6331298B1 (en) | 2001-12-18 |
| BR9306226A (pt) | 1996-12-03 |
| RU94042387A (ru) | 1996-11-10 |
| EP0646012B1 (en) | 2003-01-08 |
| GB9206861D0 (en) | 1992-05-13 |
| NO943466D0 (no) | 1994-09-16 |
| NO943466L (no) | 1994-09-16 |
| CA2131383C (en) | 2002-07-16 |
| AU3762393A (en) | 1993-11-08 |
| DE69332624T2 (de) | 2003-10-02 |
| ES2189790T3 (es) | 2003-07-16 |
| AU673161B2 (en) | 1996-10-31 |
| HU9402771D0 (en) | 1995-01-30 |
| CA2131383A1 (en) | 1993-10-14 |
| ATE230605T1 (de) | 2003-01-15 |
| JP3919212B2 (ja) | 2007-05-23 |
| DE69332624D1 (de) | 2003-02-13 |
| WO1993019769A1 (en) | 1993-10-14 |
| PT646012E (pt) | 2003-03-31 |
| NZ249937A (en) | 1996-09-25 |
| SK116894A3 (en) | 1995-02-08 |
| CZ236694A3 (en) | 1995-04-12 |
| EP0646012A1 (en) | 1995-04-05 |
| JPH07505378A (ja) | 1995-06-15 |
| JP2005290009A (ja) | 2005-10-20 |
| HUT68905A (en) | 1995-08-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO943466L (no) | Sårheling og behandling av fibrotiske forstyrrelser | |
| DE69331605D1 (de) | Verwendung von phenserin zur herstellung von medikamenten zur behandlung von kognitiven störungen | |
| EP0504715A3 (en) | Disposable wound treatment electrode, combination and method for utilization | |
| DE69631478D1 (de) | Verwendung von vitamin d4-derivaten zur behandlung von hauterkrankungen | |
| DE69424777D1 (de) | 3,4-diarylchromane zur behandlung von dermatitis | |
| DE59605959D1 (de) | Verwendung von Immunglobulin-Präparationen zur Herstellung eines Medikaments zur oralen Verabreichung zur Behandlung und Prophylaxe chronischer Schmerzzustände | |
| ATE225177T1 (de) | Verwendung von (+)mefloquine zur behandlung von malaria | |
| SE9101840L (sv) | Ny medicinsk anvaendning | |
| ATE142875T1 (de) | Methode zur behandlung von haarausfall | |
| AU2685892A (en) | Method of treating blood | |
| NO924290L (no) | Azabenzimidazoler for behandling av astma, artritt og lignende lidelser | |
| DK0537313T3 (da) | Arylalkylestere af 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracencarboxylsyre med terapeutisk aktivitet | |
| IT1288399B1 (it) | Medicamento per il trattamento terapeutico della maculopatia legata all'eta', della maculopatia non legata all'eta' e per la profilassi | |
| RU97101420A (ru) | Способ лечения тонзиллита | |
| ATE178336T1 (de) | Verwendung einer therapeutischen zusammensetzung zur behandlung von bronchitis | |
| NO960347D0 (no) | Anvendelse av benzydamid ved behandling av patologiske tilstander forårsaket av TNF | |
| UA10928C2 (uk) | Спосіб профілактики гіперхолестериhемії | |
| DE69732851D1 (de) | Verwendung von dextrinsulfat zur behandlung von sehr vasculären tumoren | |
| MX9700626A (es) | USO DE AZASPIRANOS EN LA REPARACIaN DE COMPOSICIONES PARA TRATAR INFECCIONES OPORTUNISTAS. | |
| RU93027489A (ru) | Способ хирургической коррекции хронических нарушений дуоденальной проходимости | |
| RU95118494A (ru) | Способ лечения летней формы псориаза | |
| RU97115829A (ru) | Способ лечения коклюша у детей | |
| FI935575L (fi) | 3-(kinolin-6-yylimetyyli)-4H-imidatsol-4-onijohdannaisia, menetelmä niiden valmistamiseksi ja niiden terapeuttinen käyttö | |
| GEU1998397Y (en) | Method for Primary Prestationary Treatment of the Wound | |
| HU9200976D0 (en) | Stabilized therapeutical preparative containing living virus, effective against viral and/or malign tumorous diseases and method for producing said preparative |