DK0652943T3 - Hæmatopoietiske, fremmende celler og anvendelse deraf - Google Patents

Hæmatopoietiske, fremmende celler og anvendelse deraf

Info

Publication number
DK0652943T3
DK0652943T3 DK93918173T DK93918173T DK0652943T3 DK 0652943 T3 DK0652943 T3 DK 0652943T3 DK 93918173 T DK93918173 T DK 93918173T DK 93918173 T DK93918173 T DK 93918173T DK 0652943 T3 DK0652943 T3 DK 0652943T3
Authority
DK
Denmark
Prior art keywords
bone marrow
cells
hematopoietic
marrow cells
engraftment
Prior art date
Application number
DK93918173T
Other languages
English (en)
Inventor
Suzanne T Ildstad
Richard L Simmons
Camillo Ricordi
Sherry M Wren
Christina Kaufman
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Application granted granted Critical
Publication of DK0652943T3 publication Critical patent/DK0652943T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22—Immunosuppressive or immunotolerising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/418—Antigens related to induction of tolerance to non-self
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93918173T 1992-07-10 1993-07-09 Hæmatopoietiske, fremmende celler og anvendelse deraf DK0652943T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US91198992A 1992-07-10 1992-07-10
US99654492A 1992-12-24 1992-12-24
US6931593A 1993-05-28 1993-05-28
PCT/US1993/006506 WO1994001534A1 (en) 1992-07-10 1993-07-09 Hematopoietic facilitatory cells and their uses

Publications (1)

Publication Number Publication Date
DK0652943T3 true DK0652943T3 (da) 2008-11-03

Family

ID=27371514

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93918173T DK0652943T3 (da) 1992-07-10 1993-07-09 Hæmatopoietiske, fremmende celler og anvendelse deraf

Country Status (12)

Country Link
EP (1) EP0652943B1 (da)
JP (1) JP3917652B2 (da)
AT (1) ATE399854T1 (da)
AU (1) AU688734B2 (da)
CA (1) CA2139877C (da)
DE (1) DE69334227D1 (da)
DK (1) DK0652943T3 (da)
ES (1) ES2309985T3 (da)
NZ (2) NZ255039A (da)
PT (1) PT652943E (da)
SG (1) SG55145A1 (da)
WO (1) WO1994001534A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG54291A1 (en) * 1994-01-05 1998-11-16 Univ Pittsburgh Monoclonal antibodies to antigens expressed by hematopoietic facilitatory cells
WO1996015227A1 (en) * 1994-11-14 1996-05-23 Novartis Ag Methods of inducing cell death of primitive hematopoietic cells and compositions for induction thereof
AU739277B2 (en) * 1997-09-10 2001-10-11 Emory University Methods for inhibiting rejection of transplanted tissues by bone grafting
ZA200704252B (en) 2004-10-25 2009-09-30 Cellerant Therapeutics Inc Methods of expanding myeloid cell populations and uses thereof
CN101421393B (zh) 2006-02-14 2013-08-14 塞勒兰特治疗公司 提高造血干细胞植入的方法和组合物
US8632768B2 (en) * 2008-05-30 2014-01-21 University Of Louisville Research Foundation, Inc. Human facilitating cells
JP6401445B2 (ja) * 2013-10-10 2018-10-10 国立大学法人 東京大学 造血幹細胞移植用の組合せ細胞製剤および生着促進剤並びにこれらの製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
EP0667904B1 (en) * 1991-11-05 2002-02-20 The Board Of Trustees Of The Leland Stanford Junior University Suppressor and progenitor cells

Also Published As

Publication number Publication date
EP0652943B1 (en) 2008-07-02
NZ299935A (en) 2000-07-28
CA2139877A1 (en) 1994-01-20
WO1994001534A1 (en) 1994-01-20
PT652943E (pt) 2008-10-09
ES2309985T3 (es) 2008-12-16
HK1010739A1 (en) 1999-06-25
DE69334227D1 (de) 2008-08-14
JPH08500009A (ja) 1996-01-09
NZ255039A (en) 1997-03-24
EP0652943A1 (en) 1995-05-17
CA2139877C (en) 2006-09-19
EP0652943A4 (en) 1996-02-07
AU4771793A (en) 1994-01-31
JP3917652B2 (ja) 2007-05-23
ATE399854T1 (de) 2008-07-15
AU688734B2 (en) 1998-03-19
SG55145A1 (en) 1998-12-21

Similar Documents

Publication Publication Date Title
Luria et al. Bone formation in organ cultures of bone marrow
Hajdu et al. Tendosynovial sarcoma. A clinicopathological study of 136 cases
Lawler et al. Cytogenetic studies on recipients of allogeneic bone marrow using the sex chromosomes as markers of cellular origin
JP2003277293A5 (da)
NZ335531A (en) Composition and methods of producing human cartilage tissue
DK1019493T3 (da) Fremstilling af hæmatopoietiske celler fra multipotente neurale stamceller
HUP9903072A2 (hu) 5,7-Dihidroxi-kromán-4-on-származékok az immunválasz elnyomására
NO20035637D0 (no) Karbonmonoksyd forbedrer resultatene av vev og organ transplantater og undertrykker apoptose
HUS1400034I1 (hu) Dialkil-fumarátok alkalmazása autoimmun betegségek kezelésére szolgáló gyógyászati készítmények elõállítására
DE60129007D1 (de) Vermehrung des weich- sowie des knochengewebes anhand von aus muskeln stammenden vorläuferzellen, sowie damit verbundene zusammensetzungen und behandlungsformen
US20040156834A1 (en) Compositions comprising bone marrow cells together with demineralized and/or mineralized bone matrix and their use in bone marrow transplantation
DK1131096T3 (da) Anti-CD20-antistofbehandling af patienter, der modtager knoglemarvs- eller periferisk blodstamcelletransplantationer
WO2003012060A3 (en) Cellular compositions which facilitate engraftment of hematopoietic stem cells while minimizing the risk of gvhd
IL141877A0 (en) Pharmaceutical compositions containing alpha4 integrin antagonists
WO2002040049A3 (en) Blockade of t cell migration into epithelial gvhd target tissues
IL153570A0 (en) Purging of cells using viruses
CA2213322A1 (en) Thiols to promote hematopoietic progenitor cell growth
PT941329E (pt) Metodo para prevenir a rejeicao de enxertos em transplantacao e para produzir uma celula-hospedeiro para terapia genetica universal utilizando activacao de linfocitos (lag-3)
EA200000058A1 (ru) Лечение посредством блокады cd154 при трансплантации ткани панкреатических островков
ATE300310T1 (de) Verfahren zur steigerung von hematopoietischen zellen
WO2002024244A3 (en) Method of preparing and processing transplant tissue
DK0652943T3 (da) Hæmatopoietiske, fremmende celler og anvendelse deraf
WO2002040640A3 (en) Methods of using cd8+/tcr- facilitating cells (fc) for the engraftment of purified hematopoietic stem cells (hsc)
WO1999061589A3 (en) Expansion of hematopoietic stem cells transduced with mdr-1 and methods of use thereof
Vigneau et al. Stem cells and kidney injury