DK0679718T3 - Fremgangsmåde til fremstilling af alfa-interferon - Google Patents

Fremgangsmåde til fremstilling af alfa-interferon

Info

Publication number
DK0679718T3
DK0679718T3 DK95104596T DK95104596T DK0679718T3 DK 0679718 T3 DK0679718 T3 DK 0679718T3 DK 95104596 T DK95104596 T DK 95104596T DK 95104596 T DK95104596 T DK 95104596T DK 0679718 T3 DK0679718 T3 DK 0679718T3
Authority
DK
Denmark
Prior art keywords
alpha
production
alpha interferon
free
ifn
Prior art date
Application number
DK95104596T
Other languages
English (en)
Inventor
Erich Hochuli
Urs Ettlin
Alfred Schacher
Karl Weyer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0679718T3 publication Critical patent/DK0679718T3/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21B—ROLLING OF METAL
    • B21B13/00—Metal-rolling stands, i.e. an assembly composed of a stand frame, rolls, and accessories
    • B21B13/06—Metal-rolling stands, i.e. an assembly composed of a stand frame, rolls, and accessories with axes of rolls arranged vertically, e.g. edgers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK95104596T 1994-04-09 1995-03-29 Fremgangsmåde til fremstilling af alfa-interferon DK0679718T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94105532 1994-04-09

Publications (1)

Publication Number Publication Date
DK0679718T3 true DK0679718T3 (da) 2001-10-22

Family

ID=8215847

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95104596T DK0679718T3 (da) 1994-04-09 1995-03-29 Fremgangsmåde til fremstilling af alfa-interferon

Country Status (7)

Country Link
US (1) US6005075A (da)
EP (2) EP1104809A1 (da)
JP (1) JP2859162B2 (da)
AT (1) ATE205256T1 (da)
DE (1) DE69522492T2 (da)
DK (1) DK0679718T3 (da)
ES (1) ES2161793T3 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW491855B (en) * 1996-08-07 2002-06-21 Csl Ltd Purification of immunoglobulins
FI106465B (fi) * 1998-06-10 2001-02-15 Suomen Punainen Risti Veripalv Menetelmä virusturvallisten farmaseuttisten koostumusten valmistamiseksi
CN101255188A (zh) * 1998-11-12 2008-09-03 先灵公司 干扰素同种型的转化方法及其产物
WO2000039280A2 (en) * 1998-12-31 2000-07-06 Viragen, Inc. Leukocyte-derived interferon preparations
JP5025874B2 (ja) 2000-03-27 2012-09-12 ジェネティクス インスティテュート，エルエルシー 高アニオン性タンパク質の精製方法
DE60213248T2 (de) * 2001-06-05 2006-11-30 Genetics Institute, LLC, Cambridge Verfahren zur reinigung hochanionischer proteine
ITBO20010426A1 (it) * 2001-07-06 2003-01-06 Alfa Wassermann Spa Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico
ITMI20012345A1 (it) * 2001-11-08 2003-05-08 Internat Ct For Genetic En Gin Procedimento per la produzione di interferone alfa di grado terapeutico
WO2003099320A1 (en) 2002-05-24 2003-12-04 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
US20060018875A1 (en) * 2004-06-14 2006-01-26 Blatt Lawrence M Interferon compositions and methods of use thereof
WO2009090056A2 (en) 2008-01-18 2009-07-23 F. Hoffmann-La Roche Ag Purification of not-glycosylated polypeptides
US20110257368A1 (en) 2008-12-23 2011-10-20 Schering Corporation Purification of recombinantly produced interferon
DE102010046817A1 (de) * 2010-09-28 2012-03-29 Sartorius Stedim Biotech Gmbh Verfahren zur Abtrennung von Viren aus einem Kontaminanten enthaltenden flüssigen Medium
CN114671944A (zh) * 2022-04-29 2022-06-28 江苏尤里卡生物科技有限公司 一种人绒毛膜促性腺激素纯化方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH657141A5 (de) * 1980-07-01 1986-08-15 Hoffmann La Roche Dns-sequenzen, rekombinante expressionsvektoren zur mikrobiellen herstellung von human-leukozyten-interferonen und transformierte mikroorganismen.
US4485038A (en) * 1982-10-19 1984-11-27 Health Research (Roswell Park Division) Method for the production and purification of human leukocyte interferon
US4620948A (en) * 1982-12-22 1986-11-04 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
CA1231306A (en) * 1983-03-03 1988-01-12 Erich Hochuli Purification of interferon
WO1986004067A1 (en) * 1984-12-27 1986-07-17 Suntory Limited Method for purifying an interferon
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
JPS6411640A (en) * 1987-07-02 1989-01-17 Engelhard Nippon Precious metal adsorbent
EP0563177A1 (en) * 1990-12-14 1993-10-06 Schering Corporation Oral administration of alpha interferon to treat lung malignancies
AU648214B2 (en) * 1991-12-31 1994-04-14 Lucky Limited Recombinant gene coding for human alpha interferon and expression vector thereof, etc.

Also Published As

Publication number Publication date
EP0679718A3 (en) 1996-08-21
JPH07322887A (ja) 1995-12-12
US6005075A (en) 1999-12-21
EP0679718A2 (en) 1995-11-02
EP1104809A1 (en) 2001-06-06
EP0679718B1 (en) 2001-09-05
DE69522492T2 (de) 2002-05-23
DE69522492D1 (de) 2001-10-11
JP2859162B2 (ja) 1999-02-17
ES2161793T3 (es) 2001-12-16
ATE205256T1 (de) 2001-09-15

Similar Documents

Publication Publication Date Title
DK0679718T3 (da) Fremgangsmåde til fremstilling af alfa-interferon
DE69031748D1 (de) Plasmabehandlung mit Metallmasken-Integration
DE69225128D1 (de) Verfahren zur Aufbereitung von sich berührendem und degradiertem Text
DE59101397D1 (de) O-glycosyliertes ifn-alpha.
DE69226253D1 (de) Plasmaätzverfahren und Reaktor zur Plasmabearbeitung
HUP9802324A3 (en) Use of ribavirin and interferon alpha for the treatment of hepatitis c
DE69829625D1 (de) Verfahren und Vorrichtung zur Behandlung von Perfluorokohlenstoff
DE69233631D1 (de) 1,3-Oxathiolane zur Behandlung von Hepatitis
DE69110359D1 (de) Zusammensetzung zur Reinigung von elektronischen und Präzisionsteilen und Reinigungsverfahren.
DE59103741D1 (de) Verfahren zur reduktiven Dehydrohalogenierung von Halogenkohlenwasserstoffen und Halogenethern.
KR950702510A (ko) 세라믹 다공체 및 이의 제조방법(Porous ceramic and process for producing the same)
ES2035668T3 (es) Uso de moleculas de adherencia intercelular y sus ligandos de union en el tratamiento del asma.
DE59403354D1 (de) Verfahren und Vorrichtung zur Entstickung von Rauchgasen
ITRM910144A1 (it) Fibra di ceramica, metallo o carbonio rivestita e procedimento diproduzione
DE59102062D1 (de) Verfahren zur biologischen Reinigung von Abluftströmen.
EP0589393A3 (en) Method for purifying an oxygen-rich exhaust gas.
DE3670195D1 (de) Verfahren und vorrichtung zur relativpositionierung von biegeschlaffen werkstuecklagen.
DE3773343D1 (de) Verfahren und vorrichtung zur herstellung von verbundkoerpern aus metall und keramik.
DE69011806D1 (de) Gesinterter Glas-Keramikkörper und Verfahren.
ATE113022T1 (de) Verfahren zur dechlorierung von höheren chloromethanen.
DE59500343D1 (de) Verfahren und Vorrichtung zur Aufbereitung von Lampen
ATE94588T1 (de) Verfahren zur herstellung und reinigung von alpha-interferon.
DE69009421D1 (de) Verfahren zum Simultananordnen und Verlöten von SMD-Bauteilen.
DE69112474D1 (de) Verfahren zur oberflächlichen Entionisierung von Glasbändern, Vorrichtung dafür und erhaltene entionisierte Produkte.
DE59303227D1 (de) Verfahren zur alpha-Chlorierung von Arylethern