DK0682655T3 - Fremgangsmåde til fremstilling af 3-amino-2-chlor-4-alkylpyridin eller 4-cycloalkylpyridiner - Google Patents
Fremgangsmåde til fremstilling af 3-amino-2-chlor-4-alkylpyridin eller 4-cycloalkylpyridinerInfo
- Publication number
- DK0682655T3 DK0682655T3 DK95902106T DK95902106T DK0682655T3 DK 0682655 T3 DK0682655 T3 DK 0682655T3 DK 95902106 T DK95902106 T DK 95902106T DK 95902106 T DK95902106 T DK 95902106T DK 0682655 T3 DK0682655 T3 DK 0682655T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- chloro
- amino
- cycloalkylpyridines
- alkylpyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4341033 | 1993-12-02 | ||
| PCT/EP1994/003988 WO1995015314A1 (de) | 1993-12-02 | 1994-12-01 | Verfahren zur herstellung von 3-amino-2-chlor-4-alkyl- bzw. 4-aryl-pyridin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0682655T3 true DK0682655T3 (da) | 2000-08-07 |
Family
ID=6503969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95902106T DK0682655T3 (da) | 1993-12-02 | 1994-12-01 | Fremgangsmåde til fremstilling af 3-amino-2-chlor-4-alkylpyridin eller 4-cycloalkylpyridiner |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5686618A (da) |
| EP (1) | EP0682655B1 (da) |
| JP (1) | JP3516454B2 (da) |
| AT (1) | ATE192437T1 (da) |
| CA (1) | CA2155214C (da) |
| DE (2) | DE59409324D1 (da) |
| DK (1) | DK0682655T3 (da) |
| ES (1) | ES2147601T3 (da) |
| GR (1) | GR3034079T3 (da) |
| PT (1) | PT682655E (da) |
| WO (1) | WO1995015314A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1070053B1 (en) * | 1999-01-22 | 2005-10-26 | Boehringer Ingelheim Pharmaceuticals Inc. | Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate |
| DE60009795T2 (de) * | 1999-01-22 | 2005-03-17 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Synthese von 3-Amino-2-Chlor-4-Methylpyridin aus Malonsäuresäurenitril und Aceton |
| US6399781B1 (en) | 2000-10-10 | 2002-06-04 | Boehringer Ingelheim Chemicals, Inc. | Process for making 3-amino-2-chloro-4-methylpyridine |
| CN114835714A (zh) * | 2022-04-01 | 2022-08-02 | 上海蓝乐鸟实业有限公司 | 一种托法替尼的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5200522A (en) * | 1991-06-11 | 1993-04-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for preparing 3-amino-2-chloro-4-alkylpyridines |
| JP3133331B2 (ja) * | 1991-06-11 | 2001-02-05 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | ３―アミノ―２―クロロ―４―アルキルピリジン類の製造方法 |
-
1994
- 1994-12-01 AT AT95902106T patent/ATE192437T1/de active
- 1994-12-01 DK DK95902106T patent/DK0682655T3/da active
- 1994-12-01 WO PCT/EP1994/003988 patent/WO1995015314A1/de not_active Ceased
- 1994-12-01 JP JP51539895A patent/JP3516454B2/ja not_active Expired - Lifetime
- 1994-12-01 PT PT95902106T patent/PT682655E/pt unknown
- 1994-12-01 DE DE59409324T patent/DE59409324D1/de not_active Expired - Lifetime
- 1994-12-01 CA CA002155214A patent/CA2155214C/en not_active Expired - Lifetime
- 1994-12-01 EP EP95902106A patent/EP0682655B1/de not_active Expired - Lifetime
- 1994-12-01 US US08/495,551 patent/US5686618A/en not_active Expired - Lifetime
- 1994-12-01 DE DE4442808A patent/DE4442808A1/de not_active Ceased
- 1994-12-01 ES ES95902106T patent/ES2147601T3/es not_active Expired - Lifetime
-
2000
- 2000-07-31 GR GR20000401771T patent/GR3034079T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0682655A1 (de) | 1995-11-22 |
| ATE192437T1 (de) | 2000-05-15 |
| EP0682655B1 (de) | 2000-05-03 |
| PT682655E (pt) | 2000-08-31 |
| CA2155214A1 (en) | 1995-06-08 |
| DE59409324D1 (de) | 2000-06-08 |
| CA2155214C (en) | 2005-03-29 |
| ES2147601T3 (es) | 2000-09-16 |
| US5686618A (en) | 1997-11-11 |
| JP3516454B2 (ja) | 2004-04-05 |
| WO1995015314A1 (de) | 1995-06-08 |
| JPH08506361A (ja) | 1996-07-09 |
| DE4442808A1 (de) | 1995-06-08 |
| GR3034079T3 (en) | 2000-11-30 |
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