DK0689550T3 - Antimikrobielle peptider fra bovine neutrofile - Google Patents

Antimikrobielle peptider fra bovine neutrofile

Info

Publication number: DK0689550T3
Authority: DK; Denmark
Prior art keywords: antimicrobial peptides; neutrophils; bovine neutrophils; rich; purified
Prior art date: 1993-03-19

Application number

DK94912855T

Other languages

English (en)

Inventor

Michael E Selsted

James S Cullor

Original Assignee

Univ California

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-19

Filing date

1994-03-15

Publication date

2003-03-17

1994-03-15 Application filed by Univ California filed Critical Univ California

2003-03-17 Application granted granted Critical

2003-03-17 Publication of DK0689550T3 publication Critical patent/DK0689550T3/da

Links

210000000440 neutrophil Anatomy 0.000 title abstract 3
102000044503 Antimicrobial Peptides Human genes 0.000 title abstract 2
108700042778 Antimicrobial Peptides Proteins 0.000 title abstract 2
241000283690 Bos taurus Species 0.000 title abstract 2
230000000845 anti-microbial effect Effects 0.000 abstract 1
102000012265 beta-defensin Human genes 0.000 abstract 1
108050002883 beta-defensin Proteins 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
235000018417 cysteine Nutrition 0.000 abstract 1
230000001086 cytosolic effect Effects 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
235000013305 food Nutrition 0.000 abstract 1
239000008187 granular material Substances 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Mycology (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Microbiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK94912855T 1993-03-19 1994-03-15 Antimikrobielle peptider fra bovine neutrofile DK0689550T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/033,873 US5459235A (en)	1993-03-19	1993-03-19	Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
PCT/US1994/003178 WO1994021672A1 (en)	1993-03-19	1994-03-15	Novel antimicrobial peptides from bovine neutrophils

Publications (1)

Publication Number	Publication Date
DK0689550T3 true DK0689550T3 (da)	2003-03-17

Family

ID=21872945

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94912855T DK0689550T3 (da)	1993-03-19	1994-03-15	Antimikrobielle peptider fra bovine neutrofile

Country Status (12)

Country	Link
US (3)	US5459235A (da)
EP (1)	EP0689550B1 (da)
JP (1)	JPH08508165A (da)
KR (1)	KR960701093A (da)
AT (1)	ATE227308T1 (da)
AU (1)	AU679739B2 (da)
CA (1)	CA2155739A1 (da)
DE (1)	DE69431654T2 (da)
DK (1)	DK0689550T3 (da)
ES (1)	ES2186684T3 (da)
PT (1)	PT689550E (da)
WO (1)	WO1994021672A1 (da)

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US4304715A (en) *	1979-06-08	1981-12-08	Derek Hudson	Enkephalin analogues
US5844072A (en)	1992-05-26	1998-12-01	University Of California	Antibiotic cryptdin peptides and methods of their use
US5631228A (en) *	1991-11-01	1997-05-20	Periodontix, Inc.	Anti-fungal and anti-bacterial histatin-based peptides
US5912230A (en) *	1991-11-01	1999-06-15	Periodontix, Inc.	Anti-fungal and anti-bacterial histatin-based peptides
US5885965A (en) *	1991-11-01	1999-03-23	Periodontix, Inc.	Anti-fungal D-amino acid histatin-based peptides
US5646119A (en) *	1991-11-01	1997-07-08	Periodontix, Inc.	D-amino acid histatin-based peptides as anti-fungal and anti-bacterial agents
US5459235A (en) *	1993-03-19	1995-10-17	The Regents Of The University Of California	Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US6159936A (en) *	1993-07-20	2000-12-12	The Regents Of The University Of California	Compositions and methods for treating and preventing microbial and viral infections
US6653442B1 (en)	1993-07-20	2003-11-25	Intrabiotics Pharmaceuticals, Inc.	Protegrins
US5693486A (en) *	1993-07-20	1997-12-02	Intrabiotics	DNA sequences encoding protegrins and protegrin analogs and their use in recombinant methods of producing protegrins
US5804558A (en) *	1993-07-20	1998-09-08	University Of California	Protegrins
US5708145A (en) *	1993-07-20	1998-01-13	University Of California	Immunglobulins reactive with protegrins
AU4865796A (en) *	1995-02-17	1996-09-04	Allergan, Inc.	Ophthalmic compositions including peptides and peptide derivatives and methods for using same
US6025326A (en) *	1995-07-07	2000-02-15	Intrabiotics Pharmaceuticals, Inc.	Compositions and methods for the prevention and treatment of oral mucositis
US5994306A (en) *	1995-11-22	1999-11-30	Intrabiotics Pharmaceuticals, Inc.	Fine-tuned protegrins
WO1997022624A2 (de) *	1995-12-16	1997-06-26	Beiersdorf Ag	Gegen bakterien, mycota und viren wirksame vertebratenproteine und dessen kosmetische zubereitungen
KR19990082383A (ko) *	1996-02-16	1999-11-25	스티븐슨 린다 에스.	항균성 펩티드 및 이의 사용법
US5916872A (en) *	1996-07-24	1999-06-29	Intrabiotics Pharmaceuticals, Inc.	Cyclic peptides having broad spectrum antimicrobial activity
US5972594A (en) *	1997-02-05	1999-10-26	University Of Pittsburgh	Method for screening for reproductive tract inflammation and preeclampsia using neutrophil defensins
US6174664B1 (en)	1997-02-05	2001-01-16	University Of Pittsburgh	Screening method for inflammatory diseases using neutrophil defensins and lactoferrin
FR2767832B1 (fr) *	1997-08-29	2001-08-10	Genset Sa	Polypeptide defensine humaine def-x, adn genomique et adnc, composition les contenant et applications au diagnostic et au traitement therapeutique
US6531573B1 (en)	1997-12-18	2003-03-11	Trustees Of Boston University	Antifungal and antibacterial peptides
AU6323598A (en) *	1998-02-06	1999-09-06	University Of Pittsburgh	Screening method for reproductive tract inflammation and preeclampsia using neutrophil defensins
US6545140B1 (en)	1998-07-13	2003-04-08	University Of Georgia Research Foundation, Inc.	DNA encoding an avian beta-defensin and uses thereof
US6335318B1 (en)	1999-05-10	2002-01-01	The Regents Of The University Of California	Antimicrobial theta defensins and methods of using same
AU2001287178A1 (en) *	2000-08-15	2002-02-25	North Carolina State University	Antimicrobial peptides isolated from mast cells
US6753407B2 (en)	2000-08-15	2004-06-22	North Carolina State University	Antimicrobial peptides isolated from fish
DE60028575T2 (de) *	2000-10-24	2007-06-28	Campina Melkunie B.V.	Peptiden reich an Cystein und/oder Glycin
US6713078B2 (en)	2001-04-18	2004-03-30	The Regents Of The University Of California	Retrocyclins: antiviral and antimicrobial peptides
US7314858B2 (en)	2001-04-18	2008-01-01	The Regents Of The University Of California	Retrocyclins: antiviral and antimicrobial peptides
EP1389126B1 (en) *	2001-04-18	2016-12-21	The Regents of The University of California	Retrocyclins: antiviral and antimicrobial peptides
US6835536B2 (en)	2001-08-21	2004-12-28	Micrologix Biotech Inc.	Antimicrobial cationic peptides and formulations thereof
AU2003215257A1 (en) *	2002-02-19	2003-09-09	The Government Of The United States Of America As Represented By The Secretary Of The Department Of	Modified defensins and their use
US7119070B2 (en) *	2002-04-30	2006-10-10	The Regents Of The University Of California	Antimicrobial theta defensins, analogs thereof, and methods of use
US20040136926A1 (en) *	2002-11-08	2004-07-15	Periathamby Antony Raj	Intra-oral drug delivery system
GB0300597D0 (en)	2003-01-10	2003-02-12	Microbiological Res Authority	Phage biofilms
ES2527994T3 (es)	2003-07-23	2015-02-03	Biocontrol Limited	Agentes terapéuticos que contienen bacteriófagos frente a P. aeruginosa
US20060008466A1 (en) *	2004-07-07	2006-01-12	University Of Saskatchewan	Methods for treating and preventing microbial infections
US20080255052A1 (en) *	2004-12-23	2008-10-16	The Regents Of The University Of California	Immunologic regulation by theta defensins
US20060217306A1 (en) *	2005-02-08	2006-09-28	Novozymes A/S	Systemic treatment of infections with defensins
GB0704553D0 (en)	2007-03-09	2007-04-18	Harper David R	Beneficial effects of bacteriophage treatments
GB0821707D0 (en) *	2008-11-28	2008-12-31	Secr Defence	Peptides
GB0821687D0 (en)	2008-11-28	2008-12-31	Secr Defence	Peptides
EP3384938A1 (en)	2011-09-12	2018-10-10	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
CA2868391A1 (en)	2012-04-02	2013-10-10	Stephane Bancel	Polynucleotides comprising n1-methyl-pseudouridine and methods for preparing the same
AU2013243948A1 (en)	2012-04-02	2014-10-30	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of proteins associated with human disease
AU2016353073A1 (en)	2015-11-10	2018-06-07	Visterra, Inc.	Antibody molecule-drug conjugates that specifically binds to lipopolysaccharide and uses thereof
CN110431150A (zh)	2017-01-18	2019-11-08	威特拉公司	抗体分子-药物偶联物及其用途
AU2021248643A1 (en)	2020-04-03	2022-10-27	Visterra, Inc.	Antibody molecule-drug conjugates and uses thereof
US11713341B1 (en)	2022-06-17	2023-08-01	Vestaron Corporation	Antimicrobial NCR13 variant peptides

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Publication number	Priority date	Publication date	Assignee	Title
US5202420A (en) *	1990-10-25	1993-04-13	The Children's Hospital Of Philadelphia	Tracheal antimicrobial peptides, dna sequences and methods for the production and use thereof
US5459235A (en) *	1993-03-19	1995-10-17	The Regents Of The University Of California	Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US5635594A (en) *	1994-03-11	1997-06-03	University Of California, Los Angeles	Gallinacins - antibiotic peptides
US5550109A (en) *	1994-05-24	1996-08-27	Magainin Pharmaceuticals Inc.	Inducible defensin peptide from mammalian epithelia

1993
- 1993-03-19 US US08/033,873 patent/US5459235A/en not_active Expired - Fee Related
1994
- 1994-03-15 ES ES94912855T patent/ES2186684T3/es not_active Expired - Lifetime
- 1994-03-15 AU AU65239/94A patent/AU679739B2/en not_active Ceased
- 1994-03-15 EP EP94912855A patent/EP0689550B1/en not_active Expired - Lifetime
- 1994-03-15 JP JP6521361A patent/JPH08508165A/ja not_active Ceased
- 1994-03-15 DE DE69431654T patent/DE69431654T2/de not_active Expired - Fee Related
- 1994-03-15 AT AT94912855T patent/ATE227308T1/de not_active IP Right Cessation
- 1994-03-15 CA CA002155739A patent/CA2155739A1/en not_active Abandoned
- 1994-03-15 WO PCT/US1994/003178 patent/WO1994021672A1/en not_active Ceased
- 1994-03-15 PT PT94912855T patent/PT689550E/pt unknown
- 1994-03-15 DK DK94912855T patent/DK0689550T3/da active
- 1994-09-29 KR KR1019950703993A patent/KR960701093A/ko not_active Abandoned
- 1994-12-13 US US08/356,832 patent/US5821224A/en not_active Expired - Fee Related
1997
- 1997-12-11 US US08/988,705 patent/US6211148B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2155739A1 (en)	1994-09-29
DE69431654D1 (de)	2002-12-12
JPH08508165A (ja)	1996-09-03
ES2186684T3 (es)	2003-05-16
US5459235A (en)	1995-10-17
AU679739B2 (en)	1997-07-10
WO1994021672A1 (en)	1994-09-29
PT689550E (pt)	2003-03-31
EP0689550B1 (en)	2002-11-06
DE69431654T2 (de)	2003-07-17
AU6523994A (en)	1994-10-11
ATE227308T1 (de)	2002-11-15
KR960701093A (ko)	1996-02-24
EP0689550A4 (en)	1998-01-07
EP0689550A1 (en)	1996-01-03
US5821224A (en)	1998-10-13
US6211148B1 (en)	2001-04-03

Publication	Publication Date	Title
DK0689550T3 (da)	2003-03-17	Antimikrobielle peptider fra bovine neutrofile
ATE202785T1 (de)	2001-07-15	Verbindungen mit wachstumshormon-freisetzenden eigenschaften
DK0749317T3 (da)	2002-10-07	Terapeutiske anvendelser af dimerprodukter af baktericidt/permeabilitetsforøgende protein
DE68927189D1 (de)	1996-10-17	Arzneimittel, die Lanthionin enthaltenden Bacteriozin enthalten, zur Verwendung als Bakterizide
DK0654078T3 (da)	2004-01-26	Thrombinblodfraktion til anvendelse i en medicinsk procedure
BR9801126A (pt)	2000-03-21	1,4-benzotiazepina-1,1-dióxidos hipolipidêmicos.
DE69030212D1 (de)	1997-04-24	Verwendung von Derivaten des 4-Phenyl-1,2,3,4-tetrahydro-1-naphthalenamins zur Behandlung von Psychose, Entzündung und als Immununterdrücker
MX9305729A (es)	1994-03-31	Formulas de proteinas de liberacion sostenida.
BR9005562A (pt)	1991-09-17	Composicao microbicida sinergetica e produto microbicida
ATE114113T1 (de)	1994-12-15	Verwendung von droloxifen bei der behandlung von knochenerkrankungen.
BR8707672A (pt)	1989-10-03	Pirazolinas inseticidas
LV12284A (lv)	1999-06-20	No kudras izdaliti bioaktivi produkti un tos saturosas farmaceitiskas un kosmetiskas kompozicijas
IL113941A (en)	2000-02-17	Perfluoroalkyl ketone inhibitors of elastase processes for making the same and pharmaceutical compositions containing them
DE69401204D1 (de)	1997-01-30	Gonadotropin enthaltende gefriergetrocknete troepfen
ATE108662T1 (de)	1994-08-15	Antimikrobielle peptide, zusammensetzungen, die diese enthalten, und verwendungen daraus.
ATE152353T1 (de)	1997-05-15	Pharmazeutische zubereitungen auf der basis von bakteriozin und deren verwendung zur behandlung gastrointestinaler beschwerden
YU15895A (sh)	1998-05-15	5-vinil i 5-etinil-hinolon karbonske kiseline postupci za njihovo pripremanje kao i njihova upotreba za pripremanje lekova
IL98910A0 (en)	1992-07-15	Polypeptide compounds having growth hormone releasing activity and pharmaceutical compositions containing them
TR200100637T2 (tr)	2001-10-22	Yeni doğal ürün türevleri
ES2192779T3 (es)	2003-10-16	Modificacion cristalina de 1-(2,6-difluorbencil)-1h-1,2,3-triazol-4-carboxamida y su uso como antiepileptico.
NZ504405A (en)	2002-09-27	Method for killing bacteria or fungi comprising contacting them mammalian haemoglobin proteins and fragments thereof
KR100488038B1 (ko)	2005-05-09	기관 보호 활성을 지닌 신규한 신체 보호 화합물 펩티드염, 이의 제조 방법 및 치료에서의 이의 용도
ATE100713T1 (de)	1994-02-15	L-alpha-glycerophosphoryl-d-myoinositol zur behandlung peripherer neuropathien und cerebropathien.
DK0722460T3 (da)	2000-03-20	Peptidderivater der er terapeutisk aktive i blodkoaguleringskaskaden, fremgangsmåde til fremstilling heraf og farmaceutiske
IT8267361A0 (it)	1982-03-22	Composizione sterilizzante e procedimento per la disinfezione di articoli mediante tale composizione