DK0697862T3 - Farmaceutiske sammensætninger og fremgangsmåder, hvor der anvendes isobutyramid til behandling af betaglobinlidelser - Google Patents
Farmaceutiske sammensætninger og fremgangsmåder, hvor der anvendes isobutyramid til behandling af betaglobinlidelserInfo
- Publication number
- DK0697862T3 DK0697862T3 DK93907532T DK93907532T DK0697862T3 DK 0697862 T3 DK0697862 T3 DK 0697862T3 DK 93907532 T DK93907532 T DK 93907532T DK 93907532 T DK93907532 T DK 93907532T DK 0697862 T3 DK0697862 T3 DK 0697862T3
- Authority
- DK
- Denmark
- Prior art keywords
- isobutyramide
- beta
- treatment
- pharmaceutical compositions
- methods employing
- Prior art date
Links
- WFKAJVHLWXSISD-UHFFFAOYSA-N isobutyramide Chemical compound CC(C)C(N)=O WFKAJVHLWXSISD-UHFFFAOYSA-N 0.000 title abstract 4
- 102100021519 Hemoglobin subunit beta Human genes 0.000 title abstract 2
- 108091005904 Hemoglobin subunit beta Proteins 0.000 title abstract 2
- 229940047889 isobutyramide Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000018020 Sickle cell-beta-thalassemia disease syndrome Diseases 0.000 abstract 1
- 206010043391 Thalassaemia beta Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000007056 sickle cell anemia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/852,511 US5439939A (en) | 1992-03-17 | 1992-03-17 | Pharmaceutical compositions and methods using isobutyramide for treating betaglobin disorders |
| PCT/US1993/002389 WO1993018761A1 (en) | 1992-03-17 | 1993-03-17 | Pharmaceutical compositions and methods using isobutyramide for treating betaglobin disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0697862T3 true DK0697862T3 (da) | 1999-12-13 |
Family
ID=25313524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93907532T DK0697862T3 (da) | 1992-03-17 | 1993-03-17 | Farmaceutiske sammensætninger og fremgangsmåder, hvor der anvendes isobutyramid til behandling af betaglobinlidelser |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5439939A (da) |
| EP (1) | EP0697862B1 (da) |
| AT (1) | ATE181235T1 (da) |
| AU (1) | AU3810693A (da) |
| DE (1) | DE69325393T2 (da) |
| DK (1) | DK0697862T3 (da) |
| ES (1) | ES2135470T3 (da) |
| GR (1) | GR3031241T3 (da) |
| SG (1) | SG48764A1 (da) |
| WO (1) | WO1993018761A1 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7910624B1 (en) | 1995-03-03 | 2011-03-22 | The Trustees Of Boston University | Compositions for the treatment of blood disorders |
| IT1273628B (it) * | 1993-06-04 | 1997-07-08 | Emerging Pharmaceutical Techno | Composizioni farmaceutiche per la cura della talassemia contenenti derivati dell'acido butirrico e in particolare isobutirramide |
| US5569675A (en) * | 1994-03-07 | 1996-10-29 | Bar Ilan University | Methods of using carboxylic acid esters to increase fetal-hemoglobin levels |
| US5700640A (en) * | 1994-09-16 | 1997-12-23 | Basf Aktiengesellschaft | Inducers of gamma globin gene expression and screening assays therefor |
| US6011000A (en) * | 1995-03-03 | 2000-01-04 | Perrine; Susan P. | Compositions for the treatment of blood disorders |
| US6822267B1 (en) * | 1997-08-20 | 2004-11-23 | Advantest Corporation | Signal transmission circuit, CMOS semiconductor device, and circuit board |
| AU774861B2 (en) | 1998-02-11 | 2004-07-08 | Douglas V Faller | Compositions and methods for the treatment of cystic fibrosis |
| US7154002B1 (en) | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| US7250514B1 (en) | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| FR2847817B1 (fr) * | 2002-11-28 | 2006-11-10 | Centre Nat Rech Scient | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires |
| US7375228B2 (en) | 2003-03-17 | 2008-05-20 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| EP1658074B1 (en) * | 2003-08-01 | 2012-11-07 | Fibrogen, Inc. | Inhibitors of 2-oxoglutarate dioxygenase as gamma globin inducers |
| US7642275B2 (en) | 2004-12-16 | 2010-01-05 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| JP2008540574A (ja) | 2005-05-11 | 2008-11-20 | タケダ サン ディエゴ インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
| CA2615105A1 (en) | 2005-07-14 | 2007-01-25 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| US20070185045A1 (en) * | 2006-02-06 | 2007-08-09 | Ratcliffe Peter J | Inhibitors of 2-oxoglutarate dioxygenase as gamma globin inducers |
| US20110086869A1 (en) | 2009-09-24 | 2011-04-14 | The Trustees Of Boston University | Methods for treating viral disorders |
| WO2011072086A1 (en) | 2009-12-08 | 2011-06-16 | Hemaquest Pharmaceuticals, Inc. | Methods and low dose regimens for treating red blood cell disorders |
| US20110245154A1 (en) | 2010-03-11 | 2011-10-06 | Hemaquest Pharmaceuticals, Inc. | Methods and Compositions for Treating Viral or Virally-Induced Conditions |
| WO2013119800A1 (en) | 2012-02-07 | 2013-08-15 | Massachusetts Institute Of Technology | Use of antagonists of ghrelin or ghrelin receptor to prevent or treat stress-sensitive psychiatric illness |
| US9724396B2 (en) | 2013-03-15 | 2017-08-08 | Massachusetts Institute Of Technology | Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness |
| US20160106821A1 (en) * | 2014-10-20 | 2016-04-21 | Massachusetts Institute Of Technology | Functional ghrelin receptor antagonism during pregnancy to prevent stress-associated mental illness in offspring and mothers |
| US10317418B2 (en) | 2015-02-24 | 2019-06-11 | Massachusetts Institute Of Technology | Use of ghrelin or functional ghrelin receptor agonists to prevent and treat stress-sensitive psychiatric illness |
| TWI853940B (zh) | 2019-05-31 | 2024-09-01 | 美商維拉克塔股份有限公司 | 以組蛋白去乙醯酶抑制劑治療病毒相關癌症之方法 |
| MX2024004801A (es) | 2021-10-19 | 2024-06-28 | Akirabio Inc | Composiciones que comprenden análogos de 2'- desoxicitidina, y uso de las mismas para el tratamiento de anemia de células falciformes, talasemia y cánceres. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4482571A (en) * | 1982-06-21 | 1984-11-13 | University Of Pittsburgh | Sickle cell anemia treatment and compound |
| US4822821A (en) * | 1986-10-10 | 1989-04-18 | Children's Hospital Medical Center Of Northern California | Method for augmenting fetal hemoglobin |
| US5025029A (en) * | 1986-10-10 | 1991-06-18 | Children's Hospital Medical Center Of Northern California | Method for augmenting fetal hemoglobin |
| SG86966A1 (en) * | 1988-11-29 | 2002-03-19 | Childrens Hosp Medical Center | Medicament for augmenting fetal hemoglobin |
-
1992
- 1992-03-17 US US07/852,511 patent/US5439939A/en not_active Expired - Fee Related
-
1993
- 1993-03-17 AU AU38106/93A patent/AU3810693A/en not_active Abandoned
- 1993-03-17 SG SG1996001424A patent/SG48764A1/en unknown
- 1993-03-17 DK DK93907532T patent/DK0697862T3/da active
- 1993-03-17 DE DE69325393T patent/DE69325393T2/de not_active Expired - Fee Related
- 1993-03-17 ES ES93907532T patent/ES2135470T3/es not_active Expired - Lifetime
- 1993-03-17 AT AT93907532T patent/ATE181235T1/de not_active IP Right Cessation
- 1993-03-17 WO PCT/US1993/002389 patent/WO1993018761A1/en not_active Ceased
- 1993-03-17 EP EP93907532A patent/EP0697862B1/en not_active Expired - Lifetime
-
1999
- 1999-09-16 GR GR990402332T patent/GR3031241T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU3810693A (en) | 1993-10-21 |
| ES2135470T3 (es) | 1999-11-01 |
| DE69325393D1 (de) | 1999-07-22 |
| ATE181235T1 (de) | 1999-07-15 |
| DE69325393T2 (de) | 1999-12-16 |
| GR3031241T3 (en) | 1999-12-31 |
| SG48764A1 (en) | 1998-05-18 |
| EP0697862A1 (en) | 1996-02-28 |
| WO1993018761A1 (en) | 1993-09-30 |
| US5439939A (en) | 1995-08-08 |
| EP0697862B1 (en) | 1999-06-16 |
| EP0697862A4 (en) | 1996-05-29 |
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