DK0699199T3 - Heteroatomsubstituerede alkylbenzylaminoquinuclidiner som substans P-antagonister - Google Patents

Heteroatomsubstituerede alkylbenzylaminoquinuclidiner som substans P-antagonister

Info

Publication number
DK0699199T3
DK0699199T3 DK94914619T DK94914619T DK0699199T3 DK 0699199 T3 DK0699199 T3 DK 0699199T3 DK 94914619 T DK94914619 T DK 94914619T DK 94914619 T DK94914619 T DK 94914619T DK 0699199 T3 DK0699199 T3 DK 0699199T3
Authority
DK
Denmark
Prior art keywords
alkyl
alkoxy
pct
hydrogen
independently
Prior art date
Application number
DK94914619T
Other languages
English (en)
Inventor
Kunio Satake
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0699199T3 publication Critical patent/DK0699199T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK94914619T 1993-05-19 1994-05-13 Heteroatomsubstituerede alkylbenzylaminoquinuclidiner som substans P-antagonister DK0699199T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11710293 1993-05-19
PCT/JP1994/000781 WO1994026740A1 (en) 1993-05-19 1994-05-13 Heteroatom substituted alkyl benzylaminoquinuclidines as substance p antagonists

Publications (1)

Publication Number Publication Date
DK0699199T3 true DK0699199T3 (da) 2002-12-16

Family

ID=14703456

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94914619T DK0699199T3 (da) 1993-05-19 1994-05-13 Heteroatomsubstituerede alkylbenzylaminoquinuclidiner som substans P-antagonister

Country Status (12)

Country Link
US (1) US5741797A (da)
EP (1) EP0699199B1 (da)
AT (1) ATE228129T1 (da)
AU (1) AU6691094A (da)
CA (1) CA2161886C (da)
DE (1) DE69431751T2 (da)
DK (1) DK0699199T3 (da)
ES (1) ES2184762T3 (da)
FI (1) FI942314L (da)
IL (1) IL109646A0 (da)
PT (1) PT699199E (da)
WO (1) WO1994026740A1 (da)

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JP5319518B2 (ja) 2007-04-02 2013-10-16 Ｍｓｄ株式会社 インドールジオン誘導体
AU2008269154B2 (en) 2007-06-27 2014-06-12 Merck Sharp & Dohme Llc 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
AU2009222122A1 (en) 2008-03-03 2009-09-11 Tiger Pharmatech Tyrosine kinase inhibitors
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
AU2010247735B2 (en) 2009-05-12 2015-07-16 Albany Molecular Research, Inc. Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
WO2010132437A1 (en) 2009-05-12 2010-11-18 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
PE20121172A1 (es) 2009-10-14 2012-09-05 Merck Sharp & Dohme Piperidinas sustituidas con actividad en la hdm2
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US10947234B2 (en) 2017-11-08 2021-03-16 Merck Sharp & Dohme Corp. PRMT5 inhibitors
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Also Published As

Publication number Publication date
FI942314A7 (fi) 1994-11-20
ES2184762T3 (es) 2003-04-16
WO1994026740A1 (en) 1994-11-24
DE69431751D1 (de) 2003-01-02
ATE228129T1 (de) 2002-12-15
DE69431751T2 (de) 2003-04-03
IL109646A0 (en) 1994-08-26
CA2161886A1 (en) 1994-11-24
FI942314L (fi) 1994-11-20
EP0699199B1 (en) 2002-11-20
EP0699199A1 (en) 1996-03-06
AU6691094A (en) 1994-12-12
CA2161886C (en) 1999-12-07
PT699199E (pt) 2003-01-31
US5741797A (en) 1998-04-21
FI942314A0 (fi) 1994-05-18

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