DK0706385T3 - Anvendelse af isovaleramid som et mildt anxiolytisk og et mildt sedativt middel - Google Patents

Anvendelse af isovaleramid som et mildt anxiolytisk og et mildt sedativt middel

Info

Publication number
DK0706385T3
DK0706385T3 DK94920093T DK94920093T DK0706385T3 DK 0706385 T3 DK0706385 T3 DK 0706385T3 DK 94920093 T DK94920093 T DK 94920093T DK 94920093 T DK94920093 T DK 94920093T DK 0706385 T3 DK0706385 T3 DK 0706385T3
Authority
DK
Denmark
Prior art keywords
mild
isovaleramide
anxiolytic
sedative
sedative agent
Prior art date
Application number
DK94920093T
Other languages
English (en)
Inventor
Manuel F Balandrin
Wagenen Bradford C Van
Original Assignee
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nps Pharma Inc filed Critical Nps Pharma Inc
Application granted granted Critical
Publication of DK0706385T3 publication Critical patent/DK0706385T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
DK94920093T 1993-06-11 1994-06-10 Anvendelse af isovaleramid som et mildt anxiolytisk og et mildt sedativt middel DK0706385T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/075,126 US5506268A (en) 1993-06-11 1993-06-11 Use of isovaleramide as a mild anxiolytic and sedative agent
PCT/US1994/006356 WO1994028888A1 (en) 1993-06-11 1994-06-10 Use of isovaleramide as a mild anxiolytic and mild sedative agent

Publications (1)

Publication Number Publication Date
DK0706385T3 true DK0706385T3 (da) 2002-04-29

Family

ID=22123718

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94920093T DK0706385T3 (da) 1993-06-11 1994-06-10 Anvendelse af isovaleramid som et mildt anxiolytisk og et mildt sedativt middel

Country Status (15)

Country Link
US (2) US5506268A (da)
EP (1) EP0706385B1 (da)
JP (2) JP3790267B2 (da)
KR (1) KR100341993B1 (da)
CN (1) CN1108793C (da)
AT (1) ATE213630T1 (da)
CA (1) CA2164842C (da)
DE (1) DE69429990T2 (da)
DK (1) DK0706385T3 (da)
ES (1) ES2170770T3 (da)
IL (1) IL109982A (da)
PT (1) PT706385E (da)
RU (1) RU2136271C1 (da)
TW (1) TW420606B (da)
WO (1) WO1994028888A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4113984C2 (de) * 1991-04-29 2002-05-08 Koehler Chemie Dr Franz Salze der 4-Hydroxy-Buttersäure
US5786382A (en) * 1995-11-03 1998-07-28 Childers-Zadah; Vsande Use of valerian plant and/or root as a scent-attractant for stimulating canines and felines
US6589994B1 (en) * 1996-08-30 2003-07-08 Nps Pharmaceuticals, Inc. Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound
ES2235251T3 (es) * 1996-08-30 2005-07-01 Nps Pharmaceuticals, Inc. Isovaleramida destinada al tratamiento de convulsiones, epilepsia, dolor de cabeza y espacticidad.
IL120006A (en) * 1997-01-14 2000-12-06 Yissum Res Dev Co Valnoctamide stereoisomers and a method for their synthesis and separation
EP1042275B1 (en) 1997-12-10 2005-11-09 Nps Pharmaceuticals, Inc. Anticonvulsant and central nervous system-active bis(fluorophenyl)alkylamides
DE69925251T2 (de) * 1998-03-04 2006-01-26 NPS Pharmaceuticals, Inc., Salt Lake City Zusammensetzungen enthaltend isovalerianamide zusammen mit ibuprofen
EP1576962A1 (en) * 1998-03-04 2005-09-21 Nps Pharmaceuticals, Inc. Composition comprising isovaleramide and ibuprofen
US6383527B1 (en) * 1999-03-04 2002-05-07 Nps Pharmaceuticals, Inc. Compositions comprising valerian extracts, isovaleric acid or derivatives thereof with a NSAID
US6346283B1 (en) 1999-03-26 2002-02-12 Ancile Pharmaceuticals Use of valeriana for the treatment of restless leg syndrome and related disorders
US7235258B1 (en) 1999-10-19 2007-06-26 Nps Pharmaceuticals, Inc. Sustained-release formulations for treating CNS-mediated disorders
RU2199309C1 (ru) * 2001-12-29 2003-02-27 Закрытое акционерное общество "Брынцалов-А" Лекарственное средство нобрассит седативного и анксиолитического действия
RU2209062C1 (ru) * 2002-03-19 2003-07-27 Институт физиологии им. И.П.Павлова РАН Вещество, обладающее седативным действием
NZ537003A (en) 2002-07-18 2008-03-28 Cytos Biotechnology Ag Hapten-carrier conjugates comprising virus like particles and uses thereof
US20060025477A1 (en) * 2004-07-22 2006-02-02 Artman Linda D Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
US20210130285A1 (en) 2008-03-19 2021-05-06 Aurimmed Pharma, Inc. Novel compounds advantageous in the treatment of central nervous system diseases and disorders
US10793515B2 (en) 2008-03-19 2020-10-06 Aurimmed Pharma, Inc. Compounds advantageous in the treatment of central nervous system diseases and disorders
US9212155B2 (en) 2008-03-19 2015-12-15 Aurimmed Pharma, Inc. Compounds advantageous in the treatment of central nervous system diseases and disorders
KR102222910B1 (ko) 2019-04-30 2021-03-04 차은정 평상형 원목침대
KR102227555B1 (ko) 2019-12-24 2021-03-15 주식회사 리빙테크 황토볼이 구비된 편백나무 침대

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205083A (en) * 1968-03-30 1980-05-27 Kali-Chemie Aktiengesellschaft Cyclopentapyrans
FR2306687A2 (fr) * 1975-04-08 1976-11-05 Buzas Andre Derives d'acides phenoxy-acetiques, leur preparation et leur application en therapeutique
FR2209555B1 (da) * 1972-12-11 1975-11-28 Labaz
SU668261A1 (ru) * 1977-03-21 1985-03-15 Киевский научно-исследовательский институт фармакологии и токсикологии @ -Алкил- @ -( @ -оксифенил)-амиды 3,4,5-триметоксибензойной кислоты,обладающие нейролептической активностью
US4246282A (en) * 1979-06-07 1981-01-20 Labaz ω-Dialkylalkanoic acid derivatives used to induce antianoxic activity
DE3026579A1 (de) * 1980-07-14 1982-02-11 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-dioxatricyclo (4,3,1,o(pfeil hoch)3,7(pfeil hoch)) decane
US4814183A (en) * 1987-08-31 1989-03-21 Merck & Co., Inc. Device for the controlled release of drugs with Donnan-like modulation by charged insoluble resins
FR2648814B1 (fr) * 1989-06-26 1991-10-18 Lafon Labor L'alpha (tert-butyl-aminomethyl-3,4-dichlorobenzyl)thioacetamide, son procede de preparation et son application en therapeutique
DE4008403A1 (de) * 1990-03-16 1991-09-19 Merck Patent Gmbh Glykolsaeurederivate
FR2674524B1 (fr) * 1991-03-25 1993-05-21 Adir Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
CA2164842C (en) 2006-08-29
TW420606B (en) 2001-02-01
ATE213630T1 (de) 2002-03-15
PT706385E (pt) 2002-07-31
DE69429990D1 (de) 2002-04-04
EP0706385B1 (en) 2002-02-27
US5763494A (en) 1998-06-09
JP3790267B2 (ja) 2006-06-28
CN1127472A (zh) 1996-07-24
IL109982A0 (en) 1994-10-07
KR100341993B1 (ko) 2002-11-29
RU2136271C1 (ru) 1999-09-10
CN1108793C (zh) 2003-05-21
EP0706385A1 (en) 1996-04-17
ES2170770T3 (es) 2002-08-16
US5506268A (en) 1996-04-09
WO1994028888A1 (en) 1994-12-22
JP2006169259A (ja) 2006-06-29
IL109982A (en) 1998-09-24
JPH09501908A (ja) 1997-02-25
AU7100694A (en) 1995-01-03
AU701360B2 (en) 1999-01-28
DE69429990T2 (de) 2002-09-05
CA2164842A1 (en) 1994-12-22

Similar Documents

Publication Publication Date Title
PT706385E (pt) Utilizacao de isovaleramida como agente ansiolitico suave e como agente sedativo suave
SI0725779T1 (da)
MX9405383A (es) Imidazo(4,5-c) piridin-4-aminas.
TR199801930T2 (xx) 6-Fenilpiridil-2-amin t�revleri.
NO20022998D0 (no) Farmasöytiske preparater som tilveiebringer foröket konsentrasjon av medikament
ES2172655T3 (es) Formas galenicas estables al almacenamiento.
FI961236A0 (fi) K-252a-johdannaisia, jotka lisäävät neurotrofiinin aiheuttamaa aktiivisuutta
ES2174895T3 (es) Combinaciones metalicas complejas con contenido en carbenos heterociclicos.
DE69735581D1 (de) Dosierungsform für eine verzögerte und zunehmende wirkstoffsfreisetzung
FI935900L (fi) Pullulanaasi, sitä tuottavia mikro-organismeja, menetelmiä pullulanaasin valmistamiseksi ja sen käyttö
BG103664A (en) Pharmaceutical forms containing ammoxycillin and clavulanate
GB2333453A (en) Colostrinin and uses thereof
CO4290432A1 (es) Nuevos derivados de pirazinacarboxamida, su preparacion y su utilizacion en medicamentos.
DE3582594D1 (de) Proglumid und dessen pharmazeutische zusammensetzungen zur anwendung bei der behandlung von neoplastischen affektionen.
AU622010B2 (en) Substituted 1,8-naphthyridines
ES2105605T3 (es) Antagonistas de taquiquinina, su preparacion y utilizacion en formulaciones farmaceuticas.
ID16081A (id) Penggunaan turunan trisiklik dari 1,4-dihidro-1,4-diokso-1h-naftalena senyawa-senyawa yang diperolehnya dan penerapannya dalam terapi
DE68918120D1 (de) Polyaluminiumdialkylphosphat, dieses enthaltende Ölgeliermittel und dieses enthaltende Mittel zur äusserlichen Anwendung.
AU580890B2 (en) P-acylaminobenzamides
FI944563A0 (fi) Mikro-organismeja, valmistusmenetelmä ja käyttö
NO985079L (no) Eksplosiv formulering
IL139303A0 (en) Treatment of arthritis and other similar conditions
ES2165020T3 (es) Monohidrato de famciclovir.
DK0804199T3 (da) Anvendelse af penciclovir til behandling af postherpetisk neuralgi
FI953081A7 (fi) Sekviterpeenit, niiden valmistaminen ja niiden käyttö inhibiittoreina, jotka vaikuttavat GABA-bentsodiatsepiinireseptoriin