DK0712408T3 - Tropyl-7-azaindol-3-ylcarboxyamider som antihostemiddel - Google Patents
Tropyl-7-azaindol-3-ylcarboxyamider som antihostemiddelInfo
- Publication number
- DK0712408T3 DK0712408T3 DK94921777T DK94921777T DK0712408T3 DK 0712408 T3 DK0712408 T3 DK 0712408T3 DK 94921777 T DK94921777 T DK 94921777T DK 94921777 T DK94921777 T DK 94921777T DK 0712408 T3 DK0712408 T3 DK 0712408T3
- Authority
- DK
- Denmark
- Prior art keywords
- azaindol
- pct
- ylcarboxyamides
- tropyl
- cough agent
- Prior art date
Links
- 239000003434 antitussive agent Substances 0.000 title abstract 2
- CQZYCDBHEULOFD-UHFFFAOYSA-N 1h-pyrrolo[2,3-b]pyridine-3-carboxamide Chemical class C1=CC=C2C(C(=O)N)=CNC2=N1 CQZYCDBHEULOFD-UHFFFAOYSA-N 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI001780A IT1265057B1 (it) | 1993-08-05 | 1993-08-05 | Tropil 7-azaindolil-3-carbossiamidi |
| PCT/IB1994/000234 WO1995004742A1 (en) | 1993-08-05 | 1994-08-04 | Tropyl 7-azaindol-3-ylcarboxyamides as antitussive agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0712408T3 true DK0712408T3 (da) | 1999-07-12 |
Family
ID=11366781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94921777T DK0712408T3 (da) | 1993-08-05 | 1994-08-04 | Tropyl-7-azaindol-3-ylcarboxyamider som antihostemiddel |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5750536A (da) |
| EP (1) | EP0712408B1 (da) |
| AT (1) | ATE172735T1 (da) |
| AU (1) | AU683524B2 (da) |
| CA (1) | CA2172616C (da) |
| DE (1) | DE69414256T2 (da) |
| DK (1) | DK0712408T3 (da) |
| ES (1) | ES2126766T3 (da) |
| IT (1) | IT1265057B1 (da) |
| WO (1) | WO1995004742A1 (da) |
| ZA (1) | ZA945817B (da) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1303123B1 (it) | 1998-10-13 | 2000-10-30 | Rotta Research Lab | Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed |
| US6476034B2 (en) | 2000-02-22 | 2002-11-05 | Bristol-Myers Squibb Company | Antiviral azaindole derivatives |
| US20040110785A1 (en) | 2001-02-02 | 2004-06-10 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
| US20030207910A1 (en) | 2001-02-02 | 2003-11-06 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
| US6825201B2 (en) | 2001-04-25 | 2004-11-30 | Bristol-Myers Squibb Company | Indole, azaindole and related heterocyclic amidopiperazine derivatives |
| AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
| HUP0402289A2 (hu) | 2001-10-02 | 2005-02-28 | Pharmacia & Upjohn Company | Gyógyhatású azabiciklusos csoporttal helyettesített kondenzált heteroaril-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk |
| WO2003028724A1 (en) * | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | Chk1 kinase inhibitors |
| US20030236277A1 (en) | 2002-02-14 | 2003-12-25 | Kadow John F. | Indole, azaindole and related heterocyclic pyrrolidine derivatives |
| AU2003217275A1 (en) | 2002-02-19 | 2003-09-09 | Pharmacia And Upjohn Company | Azabicyclic compounds for the treatment of disease |
| JP2005523288A (ja) | 2002-02-19 | 2005-08-04 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 疾病治療用の縮合した二環式−ｎ−架橋−複素環式芳香族カルボキサミド |
| US7037913B2 (en) | 2002-05-01 | 2006-05-02 | Bristol-Myers Squibb Company | Bicyclo 4.4.0 antiviral derivatives |
| US7348337B2 (en) | 2002-05-28 | 2008-03-25 | Bristol-Myers Squibb Company | Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides |
| US6900206B2 (en) | 2002-06-20 | 2005-05-31 | Bristol-Myers Squibb Company | Indole, azaindole and related heterocyclic sulfonylureido piperazine derivatives |
| WO2004039815A2 (en) * | 2002-11-01 | 2004-05-13 | Pharmacia & Upjohn Company Llc | Compounds having both alpha7 nachr agonist and 5ht antagonist activity for treatment of cns diseases |
| US20050075364A1 (en) | 2003-07-01 | 2005-04-07 | Kap-Sun Yeung | Indole, azaindole and related heterocyclic N-substituted piperazine derivatives |
| US20050124623A1 (en) | 2003-11-26 | 2005-06-09 | Bender John A. | Diazaindole-dicarbonyl-piperazinyl antiviral agents |
| CA2550361C (en) | 2003-12-19 | 2014-04-29 | Prabha Ibrahim | Compounds and methods for development of ret modulators |
| WO2006001894A1 (en) * | 2004-04-22 | 2006-01-05 | Memory Pharmaceutical Corporation | Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof |
| US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
| US20060100432A1 (en) | 2004-11-09 | 2006-05-11 | Matiskella John D | Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione |
| PE20071159A1 (es) * | 2005-10-31 | 2007-11-30 | Schering Corp | Derivados de tropano 3-monosustituido como ligandos de receptores de nociceptina |
| US7851476B2 (en) | 2005-12-14 | 2010-12-14 | Bristol-Myers Squibb Company | Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine |
| US7807671B2 (en) | 2006-04-25 | 2010-10-05 | Bristol-Myers Squibb Company | Diketo-piperazine and piperidine derivatives as antiviral agents |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| JP2010533729A (ja) | 2007-07-17 | 2010-10-28 | プレキシコン，インコーポレーテッド | キナーゼ調節のための化合物と方法、及びそのための適応 |
| KR101739994B1 (ko) | 2009-04-03 | 2017-05-25 | 에프. 호프만-라 로슈 아게 | 프로판-１-술폰산 ｛３-［５-（４-클로로-페닐）-１Ｈ-피롤로［２，３-ｂ］피리딘-３-카르보닐］-２，４-디플루오로-페닐｝-아미드 조성물 및 그의 용도 |
| NZ599866A (en) | 2009-11-06 | 2014-09-26 | Plexxikon Inc | Compounds and methods for kinase modulation, and indications therefor |
| KR101911972B1 (ko) | 2011-02-07 | 2018-10-25 | 플렉시콘 인코퍼레이티드 | 키나제 조절을 위한 화합물 및 방법, 및 그에 대한 적응증 |
| TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
| US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0421681A (ja) * | 1990-05-14 | 1992-01-24 | Fujisawa Pharmaceut Co Ltd | ピロロピリジン誘導体 |
| US5260303A (en) * | 1991-03-07 | 1993-11-09 | G. D. Searle & Co. | Imidazopyridines as serotonergic 5-HT3 antagonists |
| IT1255467B (it) * | 1992-07-29 | 1995-11-02 | Dompe Farmaceutici Spa | Ammidi acriliche farmacologicamente attive |
| JPH09221681A (ja) * | 1996-02-16 | 1997-08-26 | Mitsui Petrochem Ind Ltd | プラスチックの油化方法 |
-
1993
- 1993-08-05 IT IT93MI001780A patent/IT1265057B1/it active IP Right Grant
-
1994
- 1994-08-04 EP EP94921777A patent/EP0712408B1/en not_active Expired - Lifetime
- 1994-08-04 DE DE69414256T patent/DE69414256T2/de not_active Expired - Fee Related
- 1994-08-04 DK DK94921777T patent/DK0712408T3/da active
- 1994-08-04 AT AT94921777T patent/ATE172735T1/de not_active IP Right Cessation
- 1994-08-04 CA CA002172616A patent/CA2172616C/en not_active Expired - Fee Related
- 1994-08-04 AU AU13182/95A patent/AU683524B2/en not_active Ceased
- 1994-08-04 ZA ZA945817A patent/ZA945817B/xx unknown
- 1994-08-04 WO PCT/IB1994/000234 patent/WO1995004742A1/en not_active Ceased
- 1994-08-04 ES ES94921777T patent/ES2126766T3/es not_active Expired - Lifetime
- 1994-08-04 US US08/615,173 patent/US5750536A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI931780A0 (it) | 1993-08-05 |
| EP0712408A1 (en) | 1996-05-22 |
| AU683524B2 (en) | 1997-11-13 |
| HK1011359A1 (en) | 1999-07-09 |
| ATE172735T1 (de) | 1998-11-15 |
| WO1995004742A1 (en) | 1995-02-16 |
| DE69414256D1 (de) | 1998-12-03 |
| CA2172616A1 (en) | 1995-02-16 |
| CA2172616C (en) | 2001-05-29 |
| DE69414256T2 (de) | 1999-06-02 |
| IT1265057B1 (it) | 1996-10-28 |
| AU1318295A (en) | 1995-02-28 |
| ZA945817B (en) | 1995-03-10 |
| EP0712408B1 (en) | 1998-10-28 |
| ES2126766T3 (es) | 1999-04-01 |
| ITMI931780A1 (it) | 1995-02-05 |
| US5750536A (en) | 1998-05-12 |
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