DK0730460T3 - Anvendelsen af en ester af inositoltriphosphat til behandlingen af betændelsestilstande - Google Patents

Anvendelsen af en ester af inositoltriphosphat til behandlingen af betændelsestilstande

Info

Publication number: DK0730460T3
Authority: DK; Denmark
Prior art keywords: pct; inflammatory conditions; damage; tissue damage; sec
Prior art date: 1993-11-22

Application number

DK95901676T

Other languages

English (en)

Inventor

Lars Persson

Nicola Rehnberg

Torgny Gustafsson

Original Assignee

Perstorp Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-22

Filing date

1994-11-18

Publication date

2002-09-23

1994-11-18 Application filed by Perstorp Ab filed Critical Perstorp Ab

2002-09-23 Application granted granted Critical

2002-09-23 Publication of DK0730460T3 publication Critical patent/DK0730460T3/da

Links

230000004968 inflammatory condition Effects 0.000 title abstract 3
150000002148 esters Chemical class 0.000 title abstract 2
CDAISMWEOUEBRE-UHFFFAOYSA-N inositol Chemical compound OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 title 1
235000011178 triphosphate Nutrition 0.000 title 1
239000001226 triphosphate Substances 0.000 title 1
230000006378 damage Effects 0.000 abstract 4
230000000451 tissue damage Effects 0.000 abstract 3
231100000827 tissue damage Toxicity 0.000 abstract 3
201000010099 disease Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
MMWCIQZXVOZEGG-UHFFFAOYSA-N 1,4,5-IP3 Natural products OC1C(O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(O)C1OP(O)(O)=O MMWCIQZXVOZEGG-UHFFFAOYSA-N 0.000 abstract 1
102000004506 Blood Proteins Human genes 0.000 abstract 1
108010017384 Blood Proteins Proteins 0.000 abstract 1
MMWCIQZXVOZEGG-XJTPDSDZSA-N D-myo-Inositol 1,4,5-trisphosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O MMWCIQZXVOZEGG-XJTPDSDZSA-N 0.000 abstract 1
206010015866 Extravasation Diseases 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
206010030113 Oedema Diseases 0.000 abstract 1
208000027418 Wounds and injury Diseases 0.000 abstract 1
230000001154 acute effect Effects 0.000 abstract 1
230000002776 aggregation Effects 0.000 abstract 1
238000004220 aggregation Methods 0.000 abstract 1
210000002565 arteriole Anatomy 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
230000017531 blood circulation Effects 0.000 abstract 1
210000001736 capillary Anatomy 0.000 abstract 1
230000001684 chronic effect Effects 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000036251 extravasation Effects 0.000 abstract 1
239000012530 fluid Substances 0.000 abstract 1
208000014674 injury Diseases 0.000 abstract 1
210000000056 organ Anatomy 0.000 abstract 1
230000035699 permeability Effects 0.000 abstract 1
230000008961 swelling Effects 0.000 abstract 1
230000002792 vascular Effects 0.000 abstract 1
210000000264 venule Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

DK95901676T 1993-11-22 1994-11-18 Anvendelsen af en ester af inositoltriphosphat til behandlingen af betændelsestilstande DK0730460T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9303854A SE503122C2 (sv)	1993-11-22	1993-11-22	Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd
PCT/SE1994/001095 WO1995014477A1 (en)	1993-11-22	1994-11-18	The use of an ester of inositoltrisphosphate for the treatment of inflammatory conditions

Publications (1)

Publication Number	Publication Date
DK0730460T3 true DK0730460T3 (da)	2002-09-23

Family

ID=20391829

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95901676T DK0730460T3 (da)	1993-11-22	1994-11-18	Anvendelsen af en ester af inositoltriphosphat til behandlingen af betændelsestilstande

Country Status (10)

Country	Link
US (1)	US5866557A (da)
EP (1)	EP0730460B1 (da)
JP (1)	JP4172045B2 (da)
AT (1)	ATE218871T1 (da)
AU (1)	AU1081795A (da)
DE (1)	DE69430813T2 (da)
DK (1)	DK0730460T3 (da)
ES (1)	ES2177620T3 (da)
SE (1)	SE503122C2 (da)
WO (1)	WO1995014477A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9600194D0 (sv) *	1996-01-19	1996-01-19	Perstorp Ab	A new chemical compound
ES2383673T3 (es) *	2000-09-22	2012-06-25	Jpi Commercial, Llc	Composiciones de gamma-hidroxibutirato que contienen portadores de hidrato de carbonos
JP2004518639A (ja)	2000-11-21	2004-06-24	イノロジック，インコーポレイテッド	塩化物分泌を増加しそして炎症を阻害するためのイノシトール誘導体
FR2828206B1 (fr) *	2001-08-03	2004-09-24	Centre Nat Rech Scient	Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
CA2488230C (en) *	2002-04-29	2013-04-09	Yves Claude Nicolau	Inositol pyrophosphates, and methods of use thereof
FI20021570A0 (fi) *	2002-09-03	2002-09-03	Gallen Kallela Siren Janne	Päällystetyn kirurgisen stentin paranneltu rakenne
EP2039683B1 (en) *	2002-10-03	2012-12-19	Targegen, Inc.	Vasculostatic agents and methods of use thereof
US20050250694A1 (en) *	2003-10-10	2005-11-10	Ma Jian-Xing	Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same
US20050130897A1 (en) *	2003-12-11	2005-06-16	Ma Jian-Xing	Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same
US7745423B2 (en) *	2004-07-06	2010-06-29	NormOxys, Inc	Calcium/sodium salt of inositol tripyrophosphate as an allosteric effector of hemoglobin
US20060258626A1 (en) *	2004-07-06	2006-11-16	Claude Nicolau	Use of inositol-tripyrophosphate in treating tumors and diseases
US20060106000A1 (en) *	2004-07-06	2006-05-18	Claude Nicolau	Use of inositol-tripyrophosphate in treating tumors and diseases
JP5028405B2 (ja) *	2005-03-18	2012-09-19	ノームオクシスインコーポレイテッド	ヘモグロビンのアロステリックエフェクターとしてのミオイノシトール１，６：２，３：４，５トリピロリン酸のカルシウム塩
CA2674048A1 (en) *	2006-12-29	2008-07-10	Normoxys, Inc.	Cyclitols and their derivatives and their therapeutic applications
CA2688233A1 (en) *	2007-05-01	2008-11-06	Normoxys, Inc.	Erythropoietin complementation or replacement
US20080287341A1 (en) *	2007-05-18	2008-11-20	Danyang Chen	Treatment of vascular abnormalities using nanoparticles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4515722A (en) *	1982-03-30	1985-05-07	Merck & Co., Inc.	Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
SE465951B (sv) *	1984-10-23	1991-11-25	Perstorp Ab	Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
SE8605063D0 (sv) *	1986-11-26	1986-11-26	Matti Siren	Derivatives of cyclohexane
SE464059C (sv) *	1988-09-15	1997-06-02	Perstorp Ab	Användning av inositoltrifosfat för framställning av läkemedel
CA2019878A1 (en) *	1989-09-13	1991-03-13	Robert Sabin	Method of treatment of rheumatoid arthritis using phytic acid
SE8904355D0 (sv) *	1989-12-21	1989-12-21	Perstorp Ab	Medicament

1993
- 1993-11-22 SE SE9303854A patent/SE503122C2/sv not_active IP Right Cessation
1994
- 1994-11-18 US US08/640,785 patent/US5866557A/en not_active Expired - Fee Related
- 1994-11-18 AU AU10817/95A patent/AU1081795A/en not_active Abandoned
- 1994-11-18 DK DK95901676T patent/DK0730460T3/da active
- 1994-11-18 JP JP51499395A patent/JP4172045B2/ja not_active Expired - Fee Related
- 1994-11-18 WO PCT/SE1994/001095 patent/WO1995014477A1/en not_active Ceased
- 1994-11-18 DE DE69430813T patent/DE69430813T2/de not_active Expired - Fee Related
- 1994-11-18 EP EP95901676A patent/EP0730460B1/en not_active Expired - Lifetime
- 1994-11-18 ES ES95901676T patent/ES2177620T3/es not_active Expired - Lifetime
- 1994-11-18 AT AT95901676T patent/ATE218871T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0730460A1 (en)	1996-09-11
EP0730460B1 (en)	2002-06-12
US5866557A (en)	1999-02-02
ES2177620T3 (es)	2002-12-16
WO1995014477A1 (en)	1995-06-01
DE69430813T2 (de)	2003-01-30
JP4172045B2 (ja)	2008-10-29
DE69430813D1 (de)	2002-07-18
AU1081795A (en)	1995-06-13
SE9303854L (sv)	1995-05-23
ATE218871T1 (de)	2002-06-15
JPH09505581A (ja)	1997-06-03
SE9303854D0 (sv)	1993-11-22
SE503122C2 (sv)	1996-03-25

Publication	Publication Date	Title
SE9303854D0 (sv)	1993-11-22	The use of an ester of inositoltrisphosphate for the treatment of inflammatory conditions
Nagase et al.	2005	Treatment of lymphedema with lymphaticovenular anastomoses
Çakir et al.	2004	Systemic responses to burn injury
ATE241378T1 (de)	2003-06-15	Kombinationen von vasopressin und adrenergischen wirkstoffen zur behandlung des plötzlichen herztods
Gibbons et al.	1998	Necrotizing fasciitis after tumescent liposuction
McEwan et al.	1971	Effect of hydroxyethylrutosides on blood oxygen levels and venous insufficiency symptoms in varicose veins
Mufson	1948	A new treatment for the relief of obliterative diseases of peripheral arteries
Luttwak et al.	1961	Jaundice due to Obstruction of the Common Duct by Aberrant Artery*: Demonstration of Celiac Anomaly by Translumbar Aortography and Simultaneous Choledochogram
Carlson et al.	1979	PGE1 in lschaemic Peripheral Vascular Disease
RU2179853C1 (ru)	2002-02-27	Способ профилактики и лечения ангиопатий и нейропатий при сахарном диабете
Gupta et al.	1957	Case of Reverse Coarctation Syndrome
Addis	1937	Pathogenesis of eclampsia
Talks et al.	1996	Cryoglobulinaemia masquerading as rheumatoid vasculitis: the retina provides the clue
Markland	1964	Renal artery spasm
Aissaoui et al.	2020	Symmetrical and peripheral gangrene complicating a third-degree atrioventricular block: a new presentation of a known disease
RU2235545C1 (ru)	2004-09-10	Способ лечения отморожения конечностей высоких степеней в дореактивном и раннем реактивном периодах
Bergan et al.	2000	Therapeutic management of chronic venous insufficiency: microcirculation as a target
Eszenyi-Halasy	1949	Histamine headache
Karjagi¹ et al.	2026	Adjunctive Role of Jaloukavacharana in the Management of Varicose Ulcer: A Case Report
Rupp	1943	Modern Concepts of Refrigeration Anesthesia.
BAKER et al.	1964	REGIONAL PERFUSION FOR CONTROL OF ACUTE HEMOLYTIC STREPROCOCCAL GANGRENE: A CASE REPORT
Feldman et al.	1951	Acute thrombosis of the femoral artery in an infant
Victoriana et al.	2025	NONTRADITIONAL METHODS OF TREATMENT–ASSISTANTS IN THE PREVENTION AND REHABILITATION OF PATIENTS IN MODERN MEDICINE (USING A SPECIFIC EXAMPLE)
RU2077892C1 (ru)	1997-04-27	Способ лечения рецидивирующего отека легких
RU2657929C1 (ru)	2018-06-18	Способ коррекции хронических рецидивирующих трещин губ в эксперименте