DK0742722T3 - Fremgangsmåde til at forøge biotilgængeligheden af orale farmaceutiske præparater - Google Patents

Fremgangsmåde til at forøge biotilgængeligheden af orale farmaceutiske præparater

Info

Publication number
DK0742722T3
DK0742722T3 DK95907378T DK95907378T DK0742722T3 DK 0742722 T3 DK0742722 T3 DK 0742722T3 DK 95907378 T DK95907378 T DK 95907378T DK 95907378 T DK95907378 T DK 95907378T DK 0742722 T3 DK0742722 T3 DK 0742722T3
Authority
DK
Denmark
Prior art keywords
bioavailability
compound
bioenhancer
increasing
pharmaceutical preparations
Prior art date
Application number
DK95907378T
Other languages
English (en)
Inventor
Leslie Benet
Chi Yuan Wu
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of DK0742722T3 publication Critical patent/DK0742722T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/49—Cinchonan derivatives, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK95907378T 1994-02-02 1995-01-11 Fremgangsmåde til at forøge biotilgængeligheden af orale farmaceutiske præparater DK0742722T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/190,288 US5567592A (en) 1994-02-02 1994-02-02 Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
PCT/US1995/000347 WO1995020980A1 (en) 1994-02-02 1995-01-11 Method for increasing bioavailability of oral pharmaceutical compositions

Publications (1)

Publication Number Publication Date
DK0742722T3 true DK0742722T3 (da) 2002-06-17

Family

ID=22700726

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95907378T DK0742722T3 (da) 1994-02-02 1995-01-11 Fremgangsmåde til at forøge biotilgængeligheden af orale farmaceutiske præparater

Country Status (10)

Country Link
US (3) US5567592A (da)
EP (2) EP1127579A3 (da)
JP (2) JPH09508623A (da)
AT (1) ATE216260T1 (da)
AU (1) AU1562995A (da)
CA (1) CA2177175A1 (da)
DE (1) DE69526428T2 (da)
DK (1) DK0742722T3 (da)
ES (1) ES2174928T3 (da)
WO (1) WO1995020980A1 (da)

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JP2006045244A (ja) 2006-02-16
AU1562995A (en) 1995-08-21
US5567592A (en) 1996-10-22
DE69526428T2 (de) 2002-10-10
EP0742722B1 (en) 2002-04-17
EP0742722A1 (en) 1996-11-20
CA2177175A1 (en) 1995-08-10
WO1995020980A1 (en) 1995-08-10
EP1127579A3 (en) 2004-01-21
US6028054A (en) 2000-02-22
ES2174928T3 (es) 2002-11-16
JPH09508623A (ja) 1997-09-02
US6004927A (en) 1999-12-21
DE69526428D1 (de) 2002-05-23
EP1127579A2 (en) 2001-08-29

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