DK0748312T3 - Bicykliske carbamater som leukotrien-D4-antagonister - Google Patents

Bicykliske carbamater som leukotrien-D4-antagonister

Info

Publication number
DK0748312T3
DK0748312T3 DK95904687T DK95904687T DK0748312T3 DK 0748312 T3 DK0748312 T3 DK 0748312T3 DK 95904687 T DK95904687 T DK 95904687T DK 95904687 T DK95904687 T DK 95904687T DK 0748312 T3 DK0748312 T3 DK 0748312T3
Authority
DK
Denmark
Prior art keywords
leukotriene
compounds
antagonists
treatment
bicyclic
Prior art date
Application number
DK95904687T
Other languages
Danish (da)
English (en)
Inventor
Matthew F Brown
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0748312T3 publication Critical patent/DK0748312T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
DK95904687T 1994-03-01 1995-01-19 Bicykliske carbamater som leukotrien-D4-antagonister DK0748312T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/204,037 US5439929A (en) 1994-03-01 1994-03-01 Bicyclic carbamates, pharmaceutical compositions and use
PCT/IB1995/000044 WO1995023789A1 (fr) 1994-03-01 1995-01-19 Carbamates bicycliques utilises comme antagonistes des leucotrienes d4

Publications (1)

Publication Number Publication Date
DK0748312T3 true DK0748312T3 (da) 1998-11-16

Family

ID=22756358

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95904687T DK0748312T3 (da) 1994-03-01 1995-01-19 Bicykliske carbamater som leukotrien-D4-antagonister

Country Status (11)

Country Link
US (1) US5439929A (fr)
EP (1) EP0748312B1 (fr)
JP (1) JP2818976B2 (fr)
AT (1) ATE168680T1 (fr)
CA (1) CA2184604C (fr)
DE (1) DE69503611T2 (fr)
DK (1) DK0748312T3 (fr)
ES (1) ES2119378T3 (fr)
FI (1) FI112653B (fr)
MX (1) MX9603821A (fr)
WO (1) WO1995023789A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440994B1 (en) 2000-03-29 2002-08-27 Richard J. Sanders, Jr. Method of treating acne

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
GB8607294D0 (en) * 1985-04-17 1986-04-30 Ici America Inc Heterocyclic amide derivatives
DK496086A (da) * 1985-10-17 1987-04-18 Ici America Inc Heterocykliske forbindelser
ATE113581T1 (de) * 1990-05-04 1994-11-15 Ciba Geigy Ag Substituierte indole.
US5334597A (en) * 1991-10-17 1994-08-02 Merck Frosst Canada, Inc. Indole carbamates as leukotriene antagonists
EP0539329A1 (fr) * 1991-10-25 1993-04-28 Ciba-Geigy Ag Acétylène composés, utiles comme antagonistes de leukotriènes
US5280039A (en) * 1992-11-04 1994-01-18 Pfizer Inc. Bicyclic carbamates and methods of treating inflammatory diseases using the same

Also Published As

Publication number Publication date
DE69503611T2 (de) 1998-11-26
JPH09503524A (ja) 1997-04-08
WO1995023789A1 (fr) 1995-09-08
CA2184604A1 (fr) 1995-09-08
US5439929A (en) 1995-08-08
JP2818976B2 (ja) 1998-10-30
EP0748312A1 (fr) 1996-12-18
FI112653B (fi) 2003-12-31
FI963400L (fi) 1996-08-30
MX9603821A (es) 1997-03-29
ES2119378T3 (es) 1998-10-01
EP0748312B1 (fr) 1998-07-22
DE69503611D1 (de) 1998-08-27
CA2184604C (fr) 1999-05-04
ATE168680T1 (de) 1998-08-15
FI963400A0 (fi) 1996-08-30

Similar Documents

Publication Publication Date Title
DK0730579T3 (da) Substituerede indoler som inhibitorer af phosphodiesterase-type-IV
EP0730588A1 (fr) Composes d'isoxazoline utiles comme agents anti-inflammatoires
EA200400832A1 (ru) Производные карбамата 1-алкил-1-азониабицикло [2.2.2] октана и их применение в качестве антагонистов мускаринового рецептора
FI945556A0 (fi) Tulehdustenvastaiset 3-aryyli-2-isoksatsoliinijohdannaiset
EA200100124A1 (ru) Замещенные 1,8-нафтиридин-4(1h)-оны в качестве ингибиторов фосфодиэстеразы 4
BG103725A (en) Nicotineamide derivatives
WO2006001958A3 (fr) Modulateurs heterocycliques et carbocycliques d'amino cyclopentyle de l'activite du recepteur de la chimiokine
FI935379A0 (fi) Katekoldietrar som fungerar som selektiva PDEIV-inhibitorer
HRP941000B9 (hr) Morfolin i tiomorfolin antagonisti receptora tahikinina
NZ582056A (en) Bicyclic heteroaryl compounds for treating conditions related to p2x7 receptor activation
EA200500777A1 (ru) Производные 3-(3,5-диоксо-4,5-дигидро-3h-(1,2,4)триазин-2-ил)бензамида в качестве ингибиторов p2xдля лечения воспалительных заболеваний
NO20055376D0 (no) Benzoksazinyl-amidosyklopentyl-heterosykliske modulatorer av chemokin-reseptorer
CA2487365A1 (fr) Derives de piperidine utilises comme bloqueurs des canaux potassiques
MX9504422A (es) Tetrahidropirazolopiridinas biciclicas.
BR9915904A (pt) Composto, processo de preparação do mesmo, composição farmacêutica e métodos de tratamento de distúrbios
WO2005105092A3 (fr) Modulateurs de l'activité de récepteurs de chimiokines en tétrahydropyranylcyclopentylamide disubstitué en position 3,3
DK0748312T3 (da) Bicykliske carbamater som leukotrien-D4-antagonister
DK0863873T3 (da) Indolcarbamater som leukotrienantagonister
NO20055752L (no) N-ureidoalkyl-piperidiner som modulerer forbindelser av kjemokinreseptor-aktivitet
EA200400102A1 (ru) Новые гетероарильные производные, их получение и использование
DE69504198D1 (de) Substituierte alkyldiaminderivate und ihre verwendung als tachykinin antagonisten
ATE170182T1 (de) (3,4-dioxocyclobuten-1-yl)chromen-, inden-, und dehydronaphthalenon-derivate mit einer entspannenden wirkung auf glatte muskeln
BRPI0606843A2 (pt) antagonistas de nk 1