DK0754463T3 - Stabiliserede vandige flydende præparater af blodkoagulationsfaktor XIII - Google Patents

Stabiliserede vandige flydende præparater af blodkoagulationsfaktor XIII

Info

Publication number: DK0754463T3
Authority: DK; Denmark
Prior art keywords: aqueous liquid; blood coagulation; coagulation factor; factor xiii; stabilized aqueous
Prior art date: 1995-06-05

Application number

DK96109167T

Other languages

Danish (da)

English (en)

Inventor

Naoko Kato

Shuji Kondo

Original Assignee

Hoechst Japan

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-05

Filing date

1996-06-03

Publication date

2004-06-28

1996-06-03 Application filed by Hoechst Japan filed Critical Hoechst Japan

2004-06-28 Application granted granted Critical

2004-06-28 Publication of DK0754463T3 publication Critical patent/DK0754463T3/da

Links

108010071289 Factor XIII Proteins 0.000 title abstract 3
239000007788 liquid Substances 0.000 title abstract 3
238000002360 preparation method Methods 0.000 title abstract 3
108020004511 Recombinant DNA Proteins 0.000 abstract 2
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 abstract 1
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
229930006000 Sucrose Natural products 0.000 abstract 1
WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 abstract 1
229940009098 aspartate Drugs 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
229930182830 galactose Natural products 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1
HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 1
239000000600 sorbitol Substances 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1
239000005720 sucrose Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Diabetes (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

DK96109167T 1995-06-05 1996-06-03 Stabiliserede vandige flydende præparater af blodkoagulationsfaktor XIII DK0754463T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP7137863A JPH08333277A (ja)	1995-06-05	1995-06-05	ヒト血液凝固第ｘｉｉｉ因子の安定化された水性液製剤

Publications (1)

Publication Number	Publication Date
DK0754463T3 true DK0754463T3 (da)	2004-06-28

Family

ID=15208515

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96109167T DK0754463T3 (da)	1995-06-05	1996-06-03	Stabiliserede vandige flydende præparater af blodkoagulationsfaktor XIII

Country Status (9)

Country	Link
US (1)	US6084074A (fr)
EP (1)	EP0754463B1 (fr)
JP (1)	JPH08333277A (fr)
AT (1)	ATE262315T1 (fr)
AU (1)	AU722743B2 (fr)
CA (1)	CA2178144C (fr)
DE (1)	DE69631930T2 (fr)
DK (1)	DK0754463T3 (fr)
ES (1)	ES2213759T3 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6447774B1 (en) *	1998-11-18	2002-09-10	Aventis Behring Gmbh	Stabilized protein preparations for a tissue adhesive
US7276235B2 (en) *	1998-11-18	2007-10-02	Zlb Behring Gmbh	Tissue glue with improved antiadhesive properties
DE10025001A1 (de) *	2000-05-22	2001-11-29	Aventis Behring Gmbh	Gewebekleber mit verbesserten anti-adhäsiven Eigenschaften
JP5490972B2 (ja) *	2000-08-04	2014-05-14	中外製薬株式会社	タンパク質注射製剤
US20040014657A1 (en) *	2001-11-05	2004-01-22	Jan Ohrstrom	Use of blood coagulation factor XIII for treating haemophilia A
US20040033947A1 (en) *	2001-11-08	2004-02-19	Jan Ohrstrom	Method for treating hemophilia b
EP1954308B1 (fr) *	2005-09-16	2011-09-07	Merial Ltd.	Stabilisateurs de vaccins lyophilisés
PL2198007T3 (pl) *	2007-09-14	2018-03-30	Sanofi Pasteur Biologics, Llc	Kompozycje farmaceutyczne zawierające toksoidy A i B Clostridium difficile
ES2640343T3 (es)	2008-04-21	2017-11-02	Novo Nordisk Health Care Ag	Composición de transglutaminasa anhidra
KR101668502B1 (ko)	2008-11-04	2016-10-21	아스카 세이야쿠 가부시키가이샤	난포자극호르몬 함유 수성 조성물
MX350096B (es)	2011-08-12	2017-08-25	Merial Inc	Preservación asistida con vacío de productos biológicos, en particular de vacunas.
WO2019182123A1 (fr) *	2018-03-23	2019-09-26	味の素株式会社	Préparation liquide contenant une transglutaminase
CN111500563B (zh) *	2020-05-08	2023-10-13	华兰生物工程重庆有限公司	一种从人血浆中纯化人凝血因子ⅶ的方法
JPWO2025013783A1 (fr) *	2023-07-07	2025-01-16

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2916711A1 (de) *	1979-04-25	1980-11-06	Behringwerke Ag	Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
JPS56135418A (en) *	1980-03-27	1981-10-22	Green Cross Corp:The	Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
US4470968A (en) *	1983-01-13	1984-09-11	Miles Laboratories, Inc.	Pasteurized therapeutically active blood coagulation factor concentrates
DE3808048A1 (de) *	1988-03-11	1989-09-21	Behringwerke Ag	Verfahren zum affinitaetschromatografischen reinigen von faktor xiii
US5204447A (en) *	1988-11-14	1993-04-20	Zymogenetics, Inc.	Purification of factor xiii
US5612456A (en) *	1988-11-14	1997-03-18	Zymogenetics, Inc.	Factor XIII compositions
FI943458A7 (fi) *	1992-01-22	1994-09-21	Novo Nordisk As	Aktivoitu tekijä XIII
US5395923A (en) *	1993-02-23	1995-03-07	Haemacure-Biotech, Inc.	Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
DE19508192A1 (de) *	1995-03-09	1996-09-12	Behringwerke Ag	Stabile Transglutaminasepräparate und Verfahren zu ihrer Herstellung

1995
- 1995-06-05 JP JP7137863A patent/JPH08333277A/ja not_active Withdrawn
1996
- 1996-06-03 DK DK96109167T patent/DK0754463T3/da active
- 1996-06-03 AT AT96109167T patent/ATE262315T1/de active
- 1996-06-03 EP EP96109167A patent/EP0754463B1/fr not_active Expired - Lifetime
- 1996-06-03 ES ES96109167T patent/ES2213759T3/es not_active Expired - Lifetime
- 1996-06-03 DE DE69631930T patent/DE69631930T2/de not_active Expired - Lifetime
- 1996-06-04 CA CA002178144A patent/CA2178144C/fr not_active Expired - Fee Related
- 1996-06-05 AU AU54728/96A patent/AU722743B2/en not_active Ceased
- 1996-06-05 US US08/659,212 patent/US6084074A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0754463A2 (fr)	1997-01-22
EP0754463B1 (fr)	2004-03-24
CA2178144A1 (fr)	1996-12-06
AU722743B2 (en)	2000-08-10
US6084074A (en)	2000-07-04
ATE262315T1 (de)	2004-04-15
JPH08333277A (ja)	1996-12-17
DE69631930T2 (de)	2005-01-27
AU5472896A (en)	1996-12-19
ES2213759T3 (es)	2004-09-01
EP0754463A3 (fr)	1999-02-03
CA2178144C (fr)	2008-06-03
DE69631930D1 (de)	2004-04-29

Publication	Publication Date	Title
DK0754463T3 (da)	2004-06-28	Stabiliserede vandige flydende præparater af blodkoagulationsfaktor XIII
NO993709L (no)	1999-09-28	Stabilisert blanding omfattende fibrinogen
DK0454898T3 (da)	1996-04-15	Glycosaminoglycan-modificeret protein, fremgangsmåde til fremstilling af proteinet, farmaceutiske præparater indeholdende proteinet samt anvendelse af proteinet
EP0731712A4 (fr)	2005-11-09	Compositions physiologiquement stables d'acide butyrique, de sels et de derives d'acide butyrique, utilisees comme agents antineoplasiques
ATE74519T1 (de)	1992-04-15	Waessrige loesung von fettloeslichen wirkstoffen.
CY1114000T1 (el)	2016-07-27	Σταθεροποιημενα διαλυματα τεριπαρατιδης
ATE160942T1 (de)	1997-12-15	Stabilisierte faktor viii-präparationen
EP0838221A4 (fr)	2003-01-15	Preparations lyophilisees de hgf
DK0637451T3 (da)	2000-04-03	Virussikkert blodkoagulationsfaktor XIII-præparat
EP0330049A3 (fr)	1991-01-30	Facteur XIII pour la prévention des hémorragies intraventriculaires
WO1994002611A3 (fr)	1994-03-31	Erythropoietine humaine recombinee a activite biologique modifiee
ATE322906T1 (de)	2006-04-15	Verwendung von langem pentraxin ptx3 zur behanlung von durch geänderte aktivität des fgf-2 wachstumsfaktors hervorgerufene krankheiten
ATE271125T1 (de)	2004-07-15	Neuartige tyrosinkinase
DE69227607D1 (de)	1998-12-24	Arzneimittel auf Basis von Hyaluronsäure
ATE149354T1 (de)	1997-03-15	Pharmazeutische zusammensetzung von stabilisiertem (leu 13>-motilin-hse
CA2025315A1 (fr)	1991-03-22	Solutions aqueuses contenant des proteines
EP0239644A4 (fr)	1987-10-27	Nouvelle substance physiologiquement active limitant la coagulation du sang.
DK312889D0 (da)	1989-06-23	Vaeske til konditionering af tand- eller knoglesubstanser, deres fremstilling og anvendelse
CY1106882T1 (el)	2012-09-26	Τροποποιηση βητακυτταρουλινης
ATE339168T1 (de)	2006-10-15	Vorrichtung und gel zur säurepufferung
DE59609353D1 (de)	2002-07-25	Mittel zur subkutanen Verabreichung von Protein C
ATE60578T1 (de)	1991-02-15	Prostacyclinanalog, dieses als aktives bestandteil enthaltendes, den blutumlauf verbesserndes mittel und gegen magengeschwuere wirkendes mittel.