DK0772438T3 - Anvendelse af benzothiophener til fremstilling af et medikament til reduktion af ardannelse under sårheling - Google Patents

Anvendelse af benzothiophener til fremstilling af et medikament til reduktion af ardannelse under sårheling

Info

Publication number: DK0772438T3
Authority: DK; Denmark
Prior art keywords: benzothiophenes; medicament; manufacture; wound healing; during wound
Prior art date: 1994-08-22

Application number

DK95930892T

Other languages

English (en)

Inventor

George Joseph Cullinan

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-22

Filing date

1995-08-21

Publication date

1999-11-01

1995-08-21 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1999-11-01 Application granted granted Critical

1999-11-01 Publication of DK0772438T3 publication Critical patent/DK0772438T3/da

Links

230000037390 scarring Effects 0.000 title abstract 2
FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical class C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
230000029663 wound healing Effects 0.000 title 1
RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Natural products C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
-1 hexamethyleneamino Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Silicates, Zeolites, And Molecular Sieves (AREA)
Eye Examination Apparatus (AREA)
Hydrogenated Pyridines (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrrole Compounds (AREA)

DK95930892T 1994-08-22 1995-08-21 Anvendelse af benzothiophener til fremstilling af et medikament til reduktion af ardannelse under sårheling DK0772438T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/293,851 US5550151A (en)	1994-08-22	1994-08-22	Methods of reducing scarring in wound healing
PCT/US1995/010650 WO1996005826A1 (en)	1994-08-22	1995-08-21	Methods of reducing scarring in wound healing

Publications (1)

Publication Number	Publication Date
DK0772438T3 true DK0772438T3 (da)	1999-11-01

Family

ID=23130857

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95930892T DK0772438T3 (da)	1994-08-22	1995-08-21	Anvendelse af benzothiophener til fremstilling af et medikament til reduktion af ardannelse under sårheling

Country Status (14)

Country	Link
US (1)	US5550151A (da)
EP (1)	EP0772438B1 (da)
JP (1)	JPH10504823A (da)
AT (1)	ATE179890T1 (da)
AU (1)	AU3411195A (da)
CA (1)	CA2198011A1 (da)
DE (1)	DE69509657T2 (da)
DK (1)	DK0772438T3 (da)
ES (1)	ES2131331T3 (da)
GR (1)	GR3030255T3 (da)
IL (1)	IL115023A0 (da)
MX (1)	MX9701328A (da)
WO (1)	WO1996005826A1 (da)
ZA (1)	ZA956995B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4688046B2 (ja) *	2004-11-05	2011-05-25	株式会社ポーラファルマ	肥厚性瘢痕動物モデル

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4133814A (en) *	1975-10-28	1979-01-09	Eli Lilly And Company	2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4380635A (en) *	1981-04-03	1983-04-19	Eli Lilly And Company	Synthesis of acylated benzothiophenes
US4418068A (en) *	1981-04-03	1983-11-29	Eli Lilly And Company	Antiestrogenic and antiandrugenic benzothiophenes
US5075321A (en) *	1987-03-24	1991-12-24	University Of Pennsylvania	Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes
US5395842A (en) *	1988-10-31	1995-03-07	Endorecherche Inc.	Anti-estrogenic compounds and compositions
JP3157882B2 (ja) *	1991-11-15	2001-04-16	帝国臓器製薬株式会社	新規なベンゾチオフエン誘導体

1994
- 1994-08-22 US US08/293,851 patent/US5550151A/en not_active Expired - Fee Related
1995
- 1995-08-21 EP EP95930892A patent/EP0772438B1/en not_active Expired - Lifetime
- 1995-08-21 MX MX9701328A patent/MX9701328A/es unknown
- 1995-08-21 ZA ZA9506995A patent/ZA956995B/xx unknown
- 1995-08-21 WO PCT/US1995/010650 patent/WO1996005826A1/en not_active Ceased
- 1995-08-21 CA CA002198011A patent/CA2198011A1/en not_active Abandoned
- 1995-08-21 JP JP8508264A patent/JPH10504823A/ja active Pending
- 1995-08-21 AU AU34111/95A patent/AU3411195A/en not_active Abandoned
- 1995-08-21 AT AT95930892T patent/ATE179890T1/de not_active IP Right Cessation
- 1995-08-21 DK DK95930892T patent/DK0772438T3/da active
- 1995-08-21 DE DE69509657T patent/DE69509657T2/de not_active Expired - Fee Related
- 1995-08-21 ES ES95930892T patent/ES2131331T3/es not_active Expired - Lifetime
- 1995-08-21 IL IL11502395A patent/IL115023A0/xx unknown
1999
- 1999-05-19 GR GR990401348T patent/GR3030255T3/el unknown

Also Published As

Publication number	Publication date
EP0772438B1 (en)	1999-05-12
CA2198011A1 (en)	1996-02-29
AU3411195A (en)	1996-03-14
MX9701328A (es)	1997-05-31
ATE179890T1 (de)	1999-05-15
DE69509657T2 (de)	1999-09-30
GR3030255T3 (en)	1999-08-31
WO1996005826A1 (en)	1996-02-29
EP0772438A4 (en)	1997-09-03
JPH10504823A (ja)	1998-05-12
ZA956995B (en)	1997-02-21
EP0772438A1 (en)	1997-05-14
US5550151A (en)	1996-08-27
ES2131331T3 (es)	1999-07-16
IL115023A0 (en)	1995-12-08
DE69509657D1 (de)	1999-06-17

Publication	Publication Date	Title
DK0771200T3 (da)	2000-05-15	Anvendelse af raloxifen og dets analoger til fremstilling af et medikament til behandling af virale sygdomme
MX9701360A (es)	1997-05-31	Metodos para la inhibicion de la desmielinizacion y las enfermedades de la dismielinizacion.
DK0651999T3 (da)	2002-06-17	Fremgangsmåder til inhibering af livmoderfibrose
DK0652002T3 (da)	2001-04-17	Anvendelse af 2-phenyl-3-aroylebenzothiophener til fremstilling af et medikament til hæmning af brusknedbrydning
FI934680A0 (fi)	1993-10-22	Arylmorfolin, framstaellning och anvaending
NO970786L (no)	1997-02-20	Fremgangsmåte for hemming av benprotesedegradering
MX9709466A (es)	1998-02-28	Medicamento para inhibir el melanoma.
EA199700136A1 (ru)	1997-12-30	Способы ингибирования экзогенных эстрогенов
PH31620A (en)	1999-01-12	Benzothiophenes for bone healing and fracture repair.
MX9701333A (es)	1997-05-31	Metodos para inhibir el daño neuronal.
ZA956995B (en)	1997-02-21	Methods of reducing scarring in wound healing.
MY113757A (en)	2002-05-31	Methods of inhibiting endometrial cancer
DK0771201T3 (da)	2001-05-07	Anvendelse af 2-phenyl-3-aroylbenzothiophener til fremstilling af et medikament til inhibering af primær endometrisk hyperplasi
MX9709536A (es)	1998-03-29	Metodo para reducir el factor de transcripcion bef-1.
MX9709651A (es)	1998-03-29	Metodos para modulacion del factor de transcripcion nf-kb.
MX9706072A (es)	1997-10-31	Metodos de inhibicion de la adhesion celula-celula.
MX9705697A (es)	1997-10-31	Metodos para reducir los niveles de calcio del suero.