DK0778785T3 - Fremgangsmåder og apparat til indgivelse af faste lægemiddelpræparater - Google Patents

Fremgangsmåder og apparat til indgivelse af faste lægemiddelpræparater

Info

Publication number
DK0778785T3
DK0778785T3 DK95930676T DK95930676T DK0778785T3 DK 0778785 T3 DK0778785 T3 DK 0778785T3 DK 95930676 T DK95930676 T DK 95930676T DK 95930676 T DK95930676 T DK 95930676T DK 0778785 T3 DK0778785 T3 DK 0778785T3
Authority
DK
Denmark
Prior art keywords
solid composition
housing
drug
actuator
carrier
Prior art date
Application number
DK95930676T
Other languages
English (en)
Inventor
Roland Cherif-Cheikh
Original Assignee
Delab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delab filed Critical Delab
Application granted granted Critical
Publication of DK0778785T3 publication Critical patent/DK0778785T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069Devices for implanting pellets, e.g. markers or solid medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DK95930676T 1994-09-02 1995-08-31 Fremgangsmåder og apparat til indgivelse af faste lægemiddelpræparater DK0778785T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/300,138 US5837276A (en) 1994-09-02 1994-09-02 Apparatus for the delivery of elongate solid drug compositions
US30412994A 1994-09-12 1994-09-12
PCT/IB1995/000779 WO1996007440A2 (en) 1994-09-02 1995-08-31 Methods and apparatus for the delivery of solid drug compositions

Publications (1)

Publication Number Publication Date
DK0778785T3 true DK0778785T3 (da) 2000-05-29

Family

ID=26971612

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95930676T DK0778785T3 (da) 1994-09-02 1995-08-31 Fremgangsmåder og apparat til indgivelse af faste lægemiddelpræparater

Country Status (11)

Country Link
US (4) US5837276A (da)
EP (2) EP0778785B1 (da)
AT (1) ATE188615T1 (da)
AU (1) AU3398295A (da)
DE (1) DE69514530T2 (da)
DK (1) DK0778785T3 (da)
ES (1) ES2141956T3 (da)
GR (1) GR3032947T3 (da)
PT (1) PT778785E (da)
WO (1) WO1996007440A2 (da)
ZA (1) ZA957355B (da)

Families Citing this family (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837276A (en) * 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
JP2002542183A (ja) * 1999-04-16 2002-12-10 ノボ ノルディスク アクティーゼルスカブ 成形可能な乾燥した医薬製剤
US6468264B1 (en) 1999-10-12 2002-10-22 Durect Corporation Closed exchange system
ATE323470T1 (de) * 1999-12-10 2006-05-15 Massachusetts Inst Technology Mikrochip-arzneistoffverabreichungssysteme und herstellungsverfahren
US6454759B2 (en) * 2000-02-28 2002-09-24 The Regents Of The University Of California Microfabricated injectable drug delivery system
DE60144142D1 (de) * 2000-03-02 2011-04-14 Microchips Inc Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien
ATE355813T1 (de) * 2000-07-14 2007-03-15 Novo Nordisk As Verfahren zum formen einer pharmazeutischen zusammensetzung in einem verpackungsmaterial
US6719739B2 (en) * 2000-08-30 2004-04-13 Medtronic, Inc. System and method for attaching upper and lower outer cases in an implantable drug pump
DE60116520T2 (de) * 2000-10-10 2006-08-31 Microchips, Inc., Bedford Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten
AU2002237736A1 (en) * 2000-12-21 2002-07-01 Oscar M. Bassinson Personal medication dispensing card
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
WO2002055058A2 (en) 2001-01-09 2002-07-18 Microchips, Inc. Flexible microchip devices for ophthalmic and other applications
AU2002309528A1 (en) 2001-04-02 2002-10-15 Therasense, Inc. Blood glucose tracking apparatus and methods
EP1387671A1 (en) 2001-05-03 2004-02-11 MASSACHUSETTS EYE & EAR INFIRMARY Implantable drug delivery device and use thereof
US6827250B2 (en) 2001-06-28 2004-12-07 Microchips, Inc. Methods for hermetically sealing microchip reservoir devices
GB0116341D0 (en) 2001-07-04 2001-08-29 Smith & Nephew Biodegradable polymer systems
US8454997B2 (en) 2001-12-18 2013-06-04 Novo Nordisk A/S Solid dose micro implant
GB0202233D0 (en) 2002-01-31 2002-03-20 Smith & Nephew Bioresorbable polymers
MY139059A (en) * 2002-06-24 2009-08-28 Alza Corp Reusable, spring driven autoinjector
AU2003278766A1 (en) * 2002-09-04 2004-03-29 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US6899717B2 (en) * 2002-09-18 2005-05-31 Allergan, Inc. Methods and apparatus for delivery of ocular implants
US7468065B2 (en) 2002-09-18 2008-12-23 Allergan, Inc. Apparatus for delivery of ocular implants
CN1301692C (zh) 2002-09-18 2007-02-28 阿勒根公司 眼植入物导入的器械
KR20050071498A (ko) * 2002-09-18 2005-07-07 상트르 오스피딸리에 드 루니버시떼 드 몬트리알 성장 호르몬 방출 호르몬 유사체
AU2003278881A1 (en) * 2002-09-23 2004-04-08 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
EP1617888B1 (en) 2003-04-23 2019-06-12 Valeritas, Inc. Hydraulically actuated pump for long duration medicament administration
EP2092956B1 (en) * 2003-06-06 2015-01-07 Telea Electronic Engineering S.R.L. Cosmetic device for treating skin ageing
IL157981A (en) 2003-09-17 2014-01-30 Elcam Medical Agricultural Cooperative Ass Ltd Auto injector
US7141354B2 (en) * 2003-09-30 2006-11-28 Dai Nippon Printing Co., Ltd. Photo radical generator, photo sensitive resin composition and article
US8095197B2 (en) 2003-11-03 2012-01-10 Microchips, Inc. Medical device for sensing glucose
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
WO2006014425A1 (en) 2004-07-02 2006-02-09 Biovalve Technologies, Inc. Methods and devices for delivering glp-1 and uses thereof
WO2006015299A2 (en) * 2004-07-30 2006-02-09 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
JP5107041B2 (ja) * 2004-09-01 2012-12-26 マイクロチップス・インコーポレーテッド レザバ内容物の制御された放出または曝露のための、マルチキャップレザバデバイス
US7335155B2 (en) * 2004-09-14 2008-02-26 Boston Scientific Scimed, Inc. Unitary formulation delivery device
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
WO2006081279A2 (en) * 2005-01-25 2006-08-03 Microchips, Inc. Control of drug release by transient modification of local microenvironments
JP2006210507A (ja) * 2005-01-26 2006-08-10 Renesas Technology Corp 半導体装置の製造方法および半導体製造装置
JP4913030B2 (ja) * 2005-01-31 2012-04-11 株式会社バイオセレンタック 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具
US7972295B2 (en) * 2005-03-11 2011-07-05 Boston Scientific Scimed, Inc. Apparatus and methods for delivering a bolus of therapeutic material
US8591457B2 (en) 2005-08-10 2013-11-26 Alza Corporation Method for making a needle-free jet injection drug delivery device
JP4355722B2 (ja) * 2005-11-17 2009-11-04 セイコーエプソン株式会社 流体輸送装置
WO2007103276A2 (en) 2006-03-03 2007-09-13 Smith & Nephew, Inc. Systems and methods for delivering a medicament
KR101361376B1 (ko) 2006-03-30 2014-02-10 발레리타스 인코포레이티드 복합-카트리지 유체 전달 장치
WO2007143225A2 (en) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
US8668676B2 (en) * 2006-06-19 2014-03-11 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
EP2037983A1 (en) * 2006-06-30 2009-03-25 Novo Nordisk A/S Perfusion device with compensation of medical infusion during wear-time
US9039761B2 (en) 2006-08-04 2015-05-26 Allergan, Inc. Ocular implant delivery assemblies with distal caps
AU2007325001B2 (en) 2006-11-30 2014-04-10 Smith & Nephew, Inc. Fiber reinforced composite material
US20080228056A1 (en) 2007-03-13 2008-09-18 Michael Blomquist Basal rate testing using frequent blood glucose input
WO2008113043A1 (en) * 2007-03-14 2008-09-18 University Of Washington Device and method for intraocular drug delivery
US9815240B2 (en) * 2007-04-18 2017-11-14 Smith & Nephew, Inc. Expansion moulding of shape memory polymers
ATE547129T1 (de) 2007-04-19 2012-03-15 Smith & Nephew Inc Multimodale formgedächtnis-polymere
US9770534B2 (en) * 2007-04-19 2017-09-26 Smith & Nephew, Inc. Graft fixation
US7751907B2 (en) 2007-05-24 2010-07-06 Smiths Medical Asd, Inc. Expert system for insulin pump therapy
US8221345B2 (en) 2007-05-30 2012-07-17 Smiths Medical Asd, Inc. Insulin pump based expert system
EP2214608B1 (en) 2007-11-08 2015-03-04 Alimera Sciences, Inc. Ocular implantation device
USD592746S1 (en) 2007-11-08 2009-05-19 Alimera Sciences Ocular implantation device
US20090177147A1 (en) 2008-01-07 2009-07-09 Michael Blomquist Insulin pump with insulin therapy coaching
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
US8202090B2 (en) * 2008-02-29 2012-06-19 Pharmaco-Kinesis Corporation Artificial tooth medicating apparatus for controlling, regulating, sensing, and releasing medical agents into the body
EP2296731A2 (en) * 2008-06-06 2011-03-23 Wockhardt Research Centre A device and a system for delivery of biological material
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
CA2737461A1 (en) 2008-09-19 2010-03-25 Tandem Diabetes Care, Inc. Solute concentration measurement device and related methods
US8545554B2 (en) 2009-01-16 2013-10-01 Allergan, Inc. Intraocular injector
US8573027B2 (en) 2009-02-27 2013-11-05 Tandem Diabetes Care, Inc. Methods and devices for determination of flow reservoir volume
US9250106B2 (en) 2009-02-27 2016-02-02 Tandem Diabetes Care, Inc. Methods and devices for determination of flow reservoir volume
AU2010226326B2 (en) * 2009-03-20 2015-11-26 Incube Labs, Llc Solid drug delivery apparatus, formulations and methods of use
WO2010109004A1 (en) * 2009-03-27 2010-09-30 Novo Nordisk A/S Solid dose delivery device
US8926561B2 (en) 2009-07-30 2015-01-06 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
US8882701B2 (en) 2009-12-04 2014-11-11 Smiths Medical Asd, Inc. Advanced step therapy delivery for an ambulatory infusion pump and system
US20110306820A1 (en) * 2010-06-14 2011-12-15 Coloplast A/S Method of treating incontinence
WO2012118687A1 (en) * 2011-02-28 2012-09-07 Merck Sharp & Dohme Corp. Manually operated injector with restricted injection sequence
WO2012125999A2 (en) * 2011-03-17 2012-09-20 Emory University Delivery devices and methods for delivering therapeutic agents
CN104125840B (zh) * 2011-10-04 2016-11-09 因库博实验室有限责任公司 固体药剂递送装置、制剂和使用方法
WO2013112734A1 (en) 2012-01-24 2013-08-01 The Methodist Hospital Research Institute Sustained drug delivery from solid implants with nanochannel membranes
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9238100B2 (en) 2012-06-07 2016-01-19 Tandem Diabetes Care, Inc. Device and method for training users of ambulatory medical devices
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US9492608B2 (en) 2013-03-15 2016-11-15 Tandem Diabetes Care, Inc. Method and device utilizing insulin delivery protocols
US10369340B2 (en) 2013-08-12 2019-08-06 Nanomedical Systems, Inc. Device and method for sustained release of low water solubility therapeutic agent in solubilizer
WO2016019133A1 (en) 2014-07-30 2016-02-04 Tandem Diabetes Care, Inc. Temporary suspension for closed-loop medicament therapy
US11576859B2 (en) 2015-10-23 2023-02-14 Lyndra Therapeutics, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
WO2017100367A1 (en) 2015-12-08 2017-06-15 Lyndra, Inc. Geometric configurations for gastric residence systems
US10569016B2 (en) 2015-12-29 2020-02-25 Tandem Diabetes Care, Inc. System and method for switching between closed loop and open loop control of an ambulatory infusion pump
CA3019020A1 (en) 2016-04-26 2017-11-02 Marc BLOMENKEMPER Device and method for dispensing active ingredient-containing or active ingredient-carrying strips
CN109310639A (zh) * 2016-05-27 2019-02-05 林德拉有限公司 用于胃驻留系统的材料结构
JP2019532947A (ja) 2016-09-30 2019-11-14 リンドラ,インコーポレイティド アダマンタン系薬物の持続的送達のための胃内滞留システム
WO2018156993A1 (en) * 2017-02-23 2018-08-30 Incube Labs, Llc Solid drug dispensing apparatus, formulations and methods of use
CA3066658A1 (en) 2017-06-09 2018-12-13 Lyndra, Inc. Gastric residence systems with release rate-modulating films
US11585042B2 (en) 2020-09-30 2023-02-21 Haier Us Appliance Solutions, Inc. Dryer appliance with additive dispenser
EP3978065A1 (de) * 2020-10-02 2022-04-06 Heraeus Medical GmbH Implantat zur lokalen wirkstofffreisetzung

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2513014A (en) * 1946-11-18 1950-06-27 Abbott Lab Apparatus for implanting medicinal pellets subcutaneously
US3760806A (en) * 1971-01-13 1973-09-25 Alza Corp Helical osmotic dispenser with non-planar membrane
US3995631A (en) * 1971-01-13 1976-12-07 Alza Corporation Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient
US3692027A (en) * 1971-04-23 1972-09-19 Everett H Ellinwood Jr Implanted medication dispensing device and method
US3774607A (en) * 1971-11-22 1973-11-27 Commercial Solvents Corp Pellet implant gun
US4177256A (en) * 1973-04-25 1979-12-04 Alza Corporation Osmotic bursting drug delivery device
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
FR2239989A1 (en) * 1973-08-08 1975-03-07 Aries Robert Pellets for subcutaneous treatment of animals - pref. implanted from a cartridge contg. several, by means of an injection force
US3942539A (en) * 1974-04-08 1976-03-09 Corliss Joseph J Antiseptic cleansing dental floss
US4135514A (en) * 1974-12-23 1979-01-23 Alza Corporation Osmotic releasing system for administering ophthalmic drug to eye of animal
US4086914A (en) * 1977-02-11 1978-05-02 Edwin Bailey Moore Implant injector
US4263910A (en) * 1978-09-27 1981-04-28 Eli Lilly And Company Implantate package, system and method
US4360019A (en) * 1979-02-28 1982-11-23 Andros Incorporated Implantable infusion device
US4344743A (en) * 1979-12-04 1982-08-17 Bessman Samuel P Piezoelectric driven diaphragm micro-pump
EP0047013B1 (en) * 1980-09-02 1986-01-22 Medtronic, Inc. Subcutaneously implantable lead with drug dispenser means
US4315516A (en) * 1980-09-19 1982-02-16 Joseph Zappel Continuous chain formed from a multiplicity of loops formed from dental floss material and apparatus for producing the same
US4326524A (en) * 1980-09-30 1982-04-27 Minnesota Mining And Manufacturing Company Solid dose ballistic projectile
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4451253A (en) * 1980-12-18 1984-05-29 Harman Sherman M Means and method for administering medicinals
US4340054A (en) * 1980-12-29 1982-07-20 Alza Corporation Dispenser for delivering fluids and solids
US4581018A (en) * 1983-02-08 1986-04-08 Novacor Medical Corporation Implantable infusion device
DE3317536A1 (de) * 1983-05-13 1984-11-15 Siemens AG, 1000 Berlin und 8000 München Dosiervorrichtung fuer ein medikament
CA1196864A (en) * 1983-06-10 1985-11-19 Mattheus F.A. Goosen Controlled release of injectable and implantable insulin compositions
US4753636A (en) * 1983-08-02 1988-06-28 Endocon, Inc. Subcutaneous implant kit
IL69431A (en) * 1983-08-04 1987-12-31 Omikron Scient Ltd Liquid delivery system particularly useful as an implantable micro-pump for delivering insulin or other drugs
EP0139286B1 (en) * 1983-10-14 1991-08-21 Sumitomo Pharmaceuticals Company, Limited Prolonged sustained-release preparations
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
US4886514A (en) * 1985-05-02 1989-12-12 Ivac Corporation Electrochemically driven drug dispenser
US4720384A (en) * 1985-05-03 1988-01-19 E. I. Du Pont De Nemours And Company Manufacture of hollow fine tubular drug delivery systems
US4712460A (en) * 1985-11-18 1987-12-15 Biotrack, Inc. Integrated drug dosage form and metering system
DE3688188T2 (de) * 1985-12-27 1993-10-14 Koken Kk Verfahren zur Herstellung einer Formulierung mit verzögerter Freisetzung.
US4772263A (en) * 1986-02-03 1988-09-20 Regents Of The University Of Minnesota Spring driven infusion pump
US4661103A (en) * 1986-03-03 1987-04-28 Engineering Development Associates, Ltd. Multiple implant injector
US4723958A (en) * 1986-05-23 1988-02-09 Merck & Co., Inc. Pulsatile drug delivery system
DE3789320T2 (de) * 1986-07-30 1994-06-09 Sumitomo Pharma Verabreichungsinstrument zum Einführen von festen Medikamenten.
GB8701731D0 (en) * 1987-01-27 1987-03-04 Patcentre Benelux Nv Sa Pumps
US4863736A (en) * 1987-03-16 1989-09-05 Monsanto Company Somatotropin prolonged release
US4994028A (en) * 1987-03-18 1991-02-19 Endocon, Inc. Injector for inplanting multiple pellet medicaments
CA1296231C (en) * 1987-05-26 1992-02-25 Keiji Fujioka Device for administering solid preparations
FR2618329B1 (fr) * 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
DE3802158A1 (de) * 1987-08-11 1989-02-23 Hoechst Ag Vorrichtung zur applikation von implantaten
US4936827A (en) * 1988-04-11 1990-06-26 Ivy Laboratories, Inc. Implanter applicator
US4834704A (en) * 1988-04-13 1989-05-30 Eaton Corporation Injectable infusion pump apparatus for implanting long-term dispensing module and medication in an animal and method therefor
US5350741A (en) * 1988-07-30 1994-09-27 Kanji Takada Enteric formulations of physiologically active peptides and proteins
US4976966A (en) * 1988-12-29 1990-12-11 Alza Corporation Delayed release osmotically driven fluid dispenser
US5054674A (en) * 1989-02-27 1991-10-08 Fortman Eugene J Disposable dental floss cassette dispenser system
US5226895A (en) * 1989-06-05 1993-07-13 Eli Lilly And Company Multiple dose injection pen
US5112614A (en) * 1989-09-14 1992-05-12 Alza Corporation Implantable delivery dispenser
US5110008A (en) * 1989-09-29 1992-05-05 Moulding Jr Thomas S Dispenser adapted to isolate the dispensed objects by compression between two moveable structures
US5086787A (en) * 1989-12-06 1992-02-11 Medtronic, Inc. Steroid eluting intramuscular lead
US5030216A (en) * 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
US5049141A (en) * 1990-04-25 1991-09-17 Infusaid, Inc. Programmable valve pump
KR930001079B1 (ko) * 1990-07-18 1993-02-15 한국과학기술연구원 자가 방출 조절형 인슐린 제형
IL105553A (en) * 1992-05-06 1998-01-04 Janssen Pharmaceutica Inc Solid dosage form comprising a porous network of matrix forming material which disperses rapidly in water
ES2105262T3 (es) 1992-05-18 1997-10-16 Minnesota Mining & Mfg Dispositivo de suministro de farmaco a traves de las mucosas.
DK42093D0 (da) * 1993-04-07 1993-04-07 Bukh Meditec Administrationsmetode
CA2183684C (en) * 1994-02-18 2008-07-15 Richard D. Hansen Inoculation of animals with dried, pelleted biological materials
US5837276A (en) * 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5582591A (en) * 1994-09-02 1996-12-10 Delab Delivery of solid drug compositions

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GR3032947T3 (en) 2000-07-31
US6142972A (en) 2000-11-07
WO1996007440A2 (en) 1996-03-14
EP0953362A3 (en) 2000-03-08
EP0778785B1 (en) 2000-01-12
EP0778785A2 (en) 1997-06-18
US5660846A (en) 1997-08-26
ZA957355B (en) 1996-06-25
ES2141956T3 (es) 2000-04-01
AU3398295A (en) 1996-03-27
DE69514530D1 (de) 2000-02-17
DE69514530T2 (de) 2000-07-27
WO1996007440A3 (en) 1996-05-23
EP0953362A2 (en) 1999-11-03
PT778785E (pt) 2000-04-28
US5837276A (en) 1998-11-17
ATE188615T1 (de) 2000-01-15
US6306420B1 (en) 2001-10-23

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