DK0782441T3 - Farmaceutisk kontrol af inflammation - Google Patents

Farmaceutisk kontrol af inflammation

Info

Publication number: DK0782441T3
Authority: DK; Denmark
Prior art keywords: inflammation; control; oxygenase; activity; heme
Prior art date: 1994-09-22

Application number

DK95932094T

Other languages

English (en)

Inventor

Dean Willis

Adrian Richard Moore

Derek Albert Willoughby

Original Assignee

Negma Lerads

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-22

Filing date

1995-09-22

Publication date

2003-06-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4154382&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0782441(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-09-22 Application filed by Negma Lerads filed Critical Negma Lerads

2003-06-30 Application granted granted Critical

2003-06-30 Publication of DK0782441T3 publication Critical patent/DK0782441T3/da

Links

206010061218 Inflammation Diseases 0.000 title abstract 5
230000004054 inflammatory process Effects 0.000 title abstract 5
102000016761 Haem oxygenases Human genes 0.000 abstract 5
108050006318 Haem oxygenases Proteins 0.000 abstract 5
MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
208000037976 chronic inflammation Diseases 0.000 abstract 1
208000037893 chronic inflammatory disorder Diseases 0.000 abstract 1
239000000411 inducer Substances 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
230000001737 promoting effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Inorganic Chemistry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Neurology (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Rear-View Mirror Devices That Are Mounted On The Exterior Of The Vehicle (AREA)
Mirrors, Picture Frames, Photograph Stands, And Related Fastening Devices (AREA)
Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
Medicinal Preparation (AREA)

DK95932094T 1994-09-22 1995-09-22 Farmaceutisk kontrol af inflammation DK0782441T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CA002132690A CA2132690A1 (en)	1994-09-22	1994-09-22	Control and modulation of inflammatory response in humans in need of such control and modulation
PCT/GB1995/002249 WO1996009038A2 (en)	1994-09-22	1995-09-22	Alteration of activity and/or levels of haem-oxygenase to control inflammation

Publications (1)

Publication Number	Publication Date
DK0782441T3 true DK0782441T3 (da)	2003-06-30

Family

ID=4154382

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95932094T DK0782441T3 (da)	1994-09-22	1995-09-22	Farmaceutisk kontrol af inflammation

Country Status (12)

Country	Link
EP (1)	EP0782441B1 (da)
JP (1)	JPH10506388A (da)
CN (1)	CN1213742C (da)
AT (1)	ATE233551T1 (da)
AU (1)	AU3528195A (da)
CA (1)	CA2132690A1 (da)
DE (1)	DE69529831T2 (da)
DK (1)	DK0782441T3 (da)
ES (1)	ES2192205T3 (da)
NZ (1)	NZ292963A (da)
PT (1)	PT782441E (da)
WO (1)	WO1996009038A2 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6127356A (en)	1993-10-15	2000-10-03	Duke University	Oxidant scavengers
US5756492A (en) *	1996-09-09	1998-05-26	Sangstat Medical Corporation	Graft survival prolongation with porphyrins
JP2001521939A (ja)	1997-11-03	2001-11-13	デューク・ユニバーシティー	置換されたポルフィリン類
DE69928655T2 (de)	1998-04-24	2006-08-24	Duke University	Substituierte porphyrine
CA2355066A1 (en)	1998-12-17	2000-06-22	Sangstat Medical Corporation	Extending graft survival by heme oxygenase-i expression induced immunomodulation
EP1155019B1 (en)	1999-01-25	2005-12-07	National Jewish Medical and Research Center	Substituted porphyrins and their therapeutic use
JP2005508864A (ja)	2001-06-01	2005-04-07	ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター	糖尿病の治療、または移植術における使用、または免疫寛容の誘導のためのオキシダントスカベンジャー
EP2042181A1 (en)	2002-02-04	2009-04-01	ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda.	Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
JP2005522521A (ja) *	2002-04-15	2005-07-28	ベスイスラエルデアコネスメディカルセンター	ヘムオキシゲナーゼ−１およびヘム分解産物の使用法
EP1513537A4 (en)	2002-06-07	2006-09-06	Univ Duke	Substituted porphyrins
FR2842738B1 (fr) *	2002-07-23	2006-02-10	Negma Lerads	Utilisation d'une rheine pour la preparation d'un medicament pour le traitement de l'inflammation chronique, la prevention et le traitement du rejet des transplantations d'organes et de tissus
WO2007041525A2 (en) *	2005-09-30	2007-04-12	Ovation Pharmaceuticals, Inc.	Method of treating pancreatitis
US11382895B2 (en)	2008-05-23	2022-07-12	National Jewish Health	Methods for treating injury associated with exposure to an alkylating species
ES2679918T3 (es) *	2010-02-18	2018-08-31	Vtv Therapeutics Llc	Derivados de imidazol condensados sustituidos, composiciones farmacéuticas y métodos de uso de los mismos
US9163044B2 (en)	2011-04-19	2015-10-20	Alfama, Inc.	Carbon monoxide releasing molecules and uses thereof
WO2013013179A1 (en)	2011-07-21	2013-01-24	Alfama, Inc.	Ruthenium carbon monoxide releasing molecules and uses thereof
CN105727379A (zh) *	2016-02-25	2016-07-06	顾宇春	血红素加氧酶药物洗脱支架
CN110585215B (zh) *	2019-09-19	2023-06-02	中山大学	氯化血红素及其复合物在医药中的新应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5010073A (en) *	1989-10-05	1991-04-23	The Rockefeller University	Use of liposomes as carriers for metalloporphyrins
US5102670A (en) *	1990-09-14	1992-04-07	Abraham Nader G	Method for treating eye disorders by reducing 12(r)-hydroxyeicosatetraenoic acid and 12(r)-dihydroxyeicosatrienoic acid levels
WO1992018112A1 (en) *	1991-04-19	1992-10-29	The Children's Medical Center Corporation	Method of preventing nmda receptor complex-mediated neuronal damage
AU668107B2 (en) *	1991-09-24	1996-04-26	United States Of America, Represented By The Secretary, Department Of Health And Human Services, The	Oxygen substituted derivatives of nucleophile-nitric oxide adducts as nitric oxide donor prodrugs
GB9127376D0 (en) *	1991-12-24	1992-02-19	Wellcome Found	Amidino derivatives
GB9200114D0 (en) *	1992-01-04	1992-02-26	Scras	Dual inhibitors of no synthase and cyclooxygenase
WO1994013252A1 (en) *	1992-12-10	1994-06-23	Hemogen, Inc.	Method for stimulating production of heme oxygenase using vitamin b12

1994
- 1994-09-22 CA CA002132690A patent/CA2132690A1/en not_active Abandoned
1995
- 1995-09-22 DE DE69529831T patent/DE69529831T2/de not_active Revoked
- 1995-09-22 DK DK95932094T patent/DK0782441T3/da active
- 1995-09-22 PT PT95932094T patent/PT782441E/pt unknown
- 1995-09-22 AT AT95932094T patent/ATE233551T1/de not_active IP Right Cessation
- 1995-09-22 NZ NZ292963A patent/NZ292963A/en unknown
- 1995-09-22 EP EP95932094A patent/EP0782441B1/en not_active Revoked
- 1995-09-22 ES ES95932094T patent/ES2192205T3/es not_active Expired - Lifetime
- 1995-09-22 AU AU35281/95A patent/AU3528195A/en not_active Abandoned
- 1995-09-22 WO PCT/GB1995/002249 patent/WO1996009038A2/en not_active Ceased
- 1995-09-22 CN CNB95196383XA patent/CN1213742C/zh not_active Expired - Fee Related
- 1995-09-22 JP JP8510696A patent/JPH10506388A/ja not_active Ceased

Also Published As

Publication number	Publication date
DE69529831D1 (de)	2003-04-10
WO1996009038A2 (en)	1996-03-28
AU3528195A (en)	1996-04-09
WO1996009038A3 (en)	1996-06-13
ES2192205T3 (es)	2003-10-01
JPH10506388A (ja)	1998-06-23
ATE233551T1 (de)	2003-03-15
CA2132690A1 (en)	1996-03-23
CN1213742C (zh)	2005-08-10
EP0782441A1 (en)	1997-07-09
EP0782441B1 (en)	2003-03-05
CN1166785A (zh)	1997-12-03
NZ292963A (en)	2001-06-29
PT782441E (pt)	2003-07-31
DE69529831T2 (de)	2003-12-24

Publication	Publication Date	Title
PT782441E (pt)	2003-07-31	Controlo farmaceutico da inflamacao
DE69739656D1 (de)	2009-12-31	1 inhibitor und hyaluronan als polymer mit verzögerter wirkstofffreigabe
ATE356113T1 (de)	2007-03-15	Probucolbernsteinsäureester zur hemmung der expression von vcam-1
NO20002440D0 (no)	2000-05-11	Hydroksam- og karboksylsyrederivater med MMP- og TNF- inhiberende aktivitet
ATE135231T1 (de)	1996-03-15	Verwendung von ''cartilage-inducing factor'' (cif) zur behandlung von hemato- oder lymphopoietischen krankheiten
MX9308199A (es)	1995-01-31	Inhibidores de enzima.
EP1007556A4 (en)	2000-06-14	TROPONIN SUB-UNITS AND FRAGMENTS FOR USE AS INHIBITORS OF ANGIOGENESIS
ATE88346T1 (de)	1993-05-15	Zusammensetzung mit gehalt an einem nichtsteroiden entzuendungshemmenden mittel und einem nichtbakterizidwirksamen tetracyclin.
FI964748A0 (fi)	1996-11-28	Huoneenlämpötilan sterilointiaine
FI922434A0 (fi)	1992-05-27	Produktion av rekombinant human interleukin-1-inhibitor.
DK0457950T3 (da)	1994-03-07	Anvendelse af stearidonsyre til behandling af inflammatorisk betingede sygdomme
DE69609864D1 (de)	2000-09-21	Steroidnitritesterderivate und ihre verwendung als entzündungshemmende medikamente
FI945199A0 (fi)	1994-11-04	HIV-käänteiskopioijaentsyymin uudet kinatsoliini-inhibiittorit
SE9303612D0 (sv)	1993-11-02	New use
EE9700350A (et)	1998-10-15	COMT-inhibiitorite uus kasutamine ja diabeetiliste vaskulaarsete häirete ärahoidmise meetod
ES2026485T3 (es)	1992-05-01	Esteres de salsalato con guayacol para tratar bronconeumopatias flogisticas.
HUP9902417A2 (hu)	1999-11-29	Alfa-ketoészterek, és alfa-ketoamidok acilezett enol-származékai
ES2161293T3 (es)	2001-12-01	Derivados de enol acilados como profarmacos de inhibidores de la elastasa.
AU2299592A (en)	1993-02-11	Treatment of periodontal disease with protease inhibitors
DK0673646T3 (da)	1999-08-16	Anvendelse af deoxyspergualin til fremstilling af et lægemiddel til behandling af inflammatorisk-hyperreaktive sygdomme
DK1017377T3 (da)	2002-03-04	Anvendelse af 6,7-substituerede 2-aminotetraliner til behandling af af cytokin fremkaldte inflammatoriske tilstande
NO901920L (no)	1990-04-27	Nye polypeptidforbindelser.
IT8819447A0 (it)	1988-02-17	Composizione di composti che migliorano l'attivita' analgesica, antipiretica e antinfiammatoria.
FR2690344B1 (fr)	1994-07-01	Compositions therapeutiques a dosage topique dans le traitement effectif de la psoriasis.
NO173495C (no)	1993-12-22	Analogifremgangsmaate for fremstilling av terapeutisk aktive fluorerte arachidonsyrederivater