DK0783504T3 - (1,2,4)triazolo (4,3-a)guinoxalinon-derivater, deres fremstilling og anvendelse som antagonister af ampa-receptorer - Google Patents

(1,2,4)triazolo (4,3-a)guinoxalinon-derivater, deres fremstilling og anvendelse som antagonister af ampa-receptorer

Info

Publication number
DK0783504T3
DK0783504T3 DK95930409T DK95930409T DK0783504T3 DK 0783504 T3 DK0783504 T3 DK 0783504T3 DK 95930409 T DK95930409 T DK 95930409T DK 95930409 T DK95930409 T DK 95930409T DK 0783504 T3 DK0783504 T3 DK 0783504T3
Authority
DK
Denmark
Prior art keywords
pct
triazolo
guinoxalinone
antagonists
derivatives
Prior art date
Application number
DK95930409T
Other languages
English (en)
Inventor
Flemming Elmelund Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of DK0783504T3 publication Critical patent/DK0783504T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK95930409T 1994-09-16 1995-09-12 (1,2,4)triazolo (4,3-a)guinoxalinon-derivater, deres fremstilling og anvendelse som antagonister af ampa-receptorer DK0783504T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK106594 1994-09-16
PCT/DK1995/000364 WO1996008492A1 (en) 1994-09-16 1995-09-12 [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE

Publications (1)

Publication Number Publication Date
DK0783504T3 true DK0783504T3 (da) 2000-08-14

Family

ID=8100599

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95930409T DK0783504T3 (da) 1994-09-16 1995-09-12 (1,2,4)triazolo (4,3-a)guinoxalinon-derivater, deres fremstilling og anvendelse som antagonister af ampa-receptorer

Country Status (23)

Country Link
US (1) US6001832A (da)
EP (1) EP0783504B1 (da)
JP (1) JPH10505601A (da)
CN (1) CN1083842C (da)
AT (1) ATE190616T1 (da)
AU (1) AU706737B2 (da)
CA (1) CA2200055A1 (da)
CZ (1) CZ285248B6 (da)
DE (1) DE69515680T2 (da)
DK (1) DK0783504T3 (da)
ES (1) ES2146769T3 (da)
FI (1) FI971075L (da)
GR (1) GR3033642T3 (da)
HU (1) HUT76810A (da)
IL (1) IL115300A (da)
NO (1) NO308796B1 (da)
NZ (1) NZ292107A (da)
PL (1) PL319176A1 (da)
PT (1) PT783504E (da)
RU (1) RU2149162C1 (da)
SK (1) SK282635B6 (da)
WO (1) WO1996008492A1 (da)
ZA (1) ZA957795B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9651198A (en) 1997-11-11 1999-05-31 Ono Pharmaceutical Co. Ltd. Fused pyrazine compounds
WO2008072779A1 (ja) * 2006-12-13 2008-06-19 Aska Pharmaceutical Co., Ltd. キノキサリン誘導体
BRPI1009287A2 (pt) 2009-03-05 2019-09-24 Astellas Pharma Inc composto de quinoxalina
WO2012033101A1 (ja) 2010-09-07 2012-03-15 アステラス製薬株式会社 キノキサリン化合物
US9181264B2 (en) * 2010-09-16 2015-11-10 Hutchison Medipharma Limited Fused heteroaryls and their uses

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
DD228811A1 (de) * 1984-04-17 1985-10-23 Hydrierwerk Rodleben Veb Verfahren zur herstellung von neuen triazolopyrimidinen
GB8512163D0 (en) * 1985-05-14 1985-06-19 Fujisawa Pharmaceutical Co Oxothiazolidine compound
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
DK162491D0 (da) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
WO1993020077A1 (fr) * 1992-04-03 1993-10-14 Yamanouchi Pharmaceutical Co., Ltd. Derive de quinoxalinone fondue et composition pharmaceutique le contenant
DK31093D0 (da) * 1993-03-19 1993-03-19 Novo Nordisk As
KR100304177B1 (ko) * 1993-05-06 2001-11-22 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 (1,2,4)트리아졸로(4,3-a)퀴녹살린화합물,이의제조방법및이를함유하는약제학적조성물_

Also Published As

Publication number Publication date
EP0783504B1 (en) 2000-03-15
RU2149162C1 (ru) 2000-05-20
CZ75497A3 (en) 1997-08-13
AU3380795A (en) 1996-03-29
SK282635B6 (sk) 2002-10-08
CA2200055A1 (en) 1996-03-21
IL115300A (en) 2001-06-14
CN1193974A (zh) 1998-09-23
ZA957795B (en) 1996-05-14
ES2146769T3 (es) 2000-08-16
CN1083842C (zh) 2002-05-01
FI971075A7 (fi) 1997-05-13
DE69515680D1 (de) 2000-04-20
JPH10505601A (ja) 1998-06-02
WO1996008492A1 (en) 1996-03-21
NO308796B1 (no) 2000-10-30
DE69515680T2 (de) 2000-10-19
AU706737B2 (en) 1999-06-24
SK33597A3 (en) 1998-02-04
ATE190616T1 (de) 2000-04-15
NZ292107A (en) 1999-02-25
CZ285248B6 (cs) 1999-06-16
FI971075L (fi) 1997-05-13
NO971186D0 (no) 1997-03-14
EP0783504A1 (en) 1997-07-16
US6001832A (en) 1999-12-14
HUT76810A (en) 1997-11-28
PT783504E (pt) 2000-08-31
IL115300A0 (en) 1995-12-31
PL319176A1 (en) 1997-08-04
FI971075A0 (fi) 1997-03-14
NO971186L (no) 1997-05-15
GR3033642T3 (en) 2000-10-31

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