DK0787135T3 - Vandopløslige derivater af epipodophyllotoxin, fremgangsmåde til fremstilling deraf og anvendelse som et lægemiddel til beh - Google Patents

Vandopløslige derivater af epipodophyllotoxin, fremgangsmåde til fremstilling deraf og anvendelse som et lægemiddel til beh

Info

Publication number: DK0787135T3
Authority: DK; Denmark
Prior art keywords: epipodophyllotoxin; preparation; treatment; pct; soluble derivatives
Prior art date: 1994-10-21

Application number

DK95935993T

Other languages

English (en)

Inventor

Thierry Imbert

Yves Guminski

Barbara Monse

Bridget Hill

Jean-Pierre Robin

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-21

Filing date

1995-10-20

Publication date

2000-10-23

1995-10-20 Application filed by Pf Medicament filed Critical Pf Medicament

2000-10-23 Application granted granted Critical

2000-10-23 Publication of DK0787135T3 publication Critical patent/DK0787135T3/da

Links

YJGVMLPVUAXIQN-LGWHJFRWSA-N (5s,5ar,8ar,9r)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5h-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one Chemical class COC1=C(OC)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O)[C@@H]3[C@@H]2C(OC3)=O)=C1 YJGVMLPVUAXIQN-LGWHJFRWSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
241000701806 Human papillomavirus Species 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK95935993T 1994-10-21 1995-10-20 Vandopløslige derivater af epipodophyllotoxin, fremgangsmåde til fremstilling deraf og anvendelse som et lægemiddel til beh DK0787135T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9412597A FR2725990B1 (fr)	1994-10-21	1994-10-21	Derives hydrosolubles d'epipodophyllotoxine, leur procede de preparation, leur utilisation a titre de medicament, et leur utilisation destinee aux traitements anticancereux
PCT/FR1995/001388 WO1996012727A1 (fr)	1994-10-21	1995-10-20	Derives hydrosolubles d'epipodophyllotoxine, leur procede de preparation, leur utilisation a titre de medicament, et leur utilisation destinee aux traitements anticancereux

Publications (1)

Publication Number	Publication Date
DK0787135T3 true DK0787135T3 (da)	2000-10-23

Family

ID=9468081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95935993T DK0787135T3 (da)	1994-10-21	1995-10-20	Vandopløslige derivater af epipodophyllotoxin, fremgangsmåde til fremstilling deraf og anvendelse som et lægemiddel til beh

Country Status (13)

Country	Link
US (1)	US6107284A (da)
EP (1)	EP0787135B1 (da)
JP (1)	JPH10507462A (da)
AT (1)	ATE193297T1 (da)
AU (1)	AU705248B2 (da)
DE (1)	DE69517191T2 (da)
DK (1)	DK0787135T3 (da)
ES (1)	ES2148572T3 (da)
FR (1)	FR2725990B1 (da)
GR (1)	GR3034155T3 (da)
NZ (1)	NZ294878A (da)
PT (1)	PT787135E (da)
WO (1)	WO1996012727A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2791682B1 (fr) *	1999-03-29	2001-06-22	Pf Medicament	Procede de preparation du 4'-demethyl-4'-phosphate-2", 3"-bis pentafluorophenoxyacetyl-4",6"-ethyldidene-beta-d- glucoside d'epipodophyllotoxine, et de ses sels
CA2385528C (en)	1999-10-01	2013-12-10	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
ATE407676T1 (de) *	2000-02-28	2008-09-15	Univ British Columbia	Topoisomerasehemmern zur behandlung von chirurgischen verklebungen
SE0002045D0 (sv) *	2000-05-31	2000-05-31	Sahltech Ab	New use
FR2830760B1 (fr) *	2001-10-12	2004-06-04	Pf Medicament	Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique
FR2854079B1 (fr)	2003-04-25	2007-11-30	Pf Medicament	Procede de preparation de complexes moleculaires
FR2859724B1 (fr) *	2003-09-16	2005-12-30	Pf Medicament	Compose cristallin sous forme libre ou hemiethanolate de 4'-demethyl-4'-phosphate-2",3"-bispentafluorophenoxyacetyl- 4",6"-ethylidene-beta-d-glucoside d'epipodophyllotoxine
FR2869035B1 (fr) *	2004-04-16	2006-07-14	Pierre Fabre Medicament Sa	Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
RU2013103763A (ru)	2010-07-02	2014-08-10	Ангиохем Инк.	Короткие и содержащие d-аминокислоты полипептиды для терапевтических конъюгатов и их применения
CN102070645B (zh) *	2011-01-07	2015-04-22	兰州大学	一种脱氧鬼臼毒素类化合物及其制备与应用
WO2023092188A1 (en) *	2021-11-26	2023-06-01	DemAgtech Pty Ltd	"compounds and methods"

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4904768A (en) *	1987-08-04	1990-02-27	Bristol-Myers Company	Epipodophyllotoxin glucoside 4'-phosphate derivatives
US5066645A (en) *	1989-09-01	1991-11-19	Bristol-Myers Company	Epipodophyllotoxin altroside derivatives
FR2658824B1 (fr) *	1990-02-27	1992-07-03	Pf Medicament	Tris acetyl-2",3",4' ethylidene-4",6" beta-d-glucopyranosides, leur preparation et leur utilisation pour la preparation d'ethylidene beta-d-glucopyranoside de demethyl-4' epipodophyllotoxine.
FR2699535B1 (fr) *	1992-12-22	1995-03-17	Pf Medicament	Dérivés de l'étoposide, leur procédé de préparation, leur utilisation à titre de médicament et leur utilisation pour la préparation d'un médicament destiné au traitement anticancéreux.

1994
- 1994-10-21 FR FR9412597A patent/FR2725990B1/fr not_active Expired - Fee Related
1995
- 1995-10-20 NZ NZ294878A patent/NZ294878A/xx unknown
- 1995-10-20 AT AT95935993T patent/ATE193297T1/de not_active IP Right Cessation
- 1995-10-20 ES ES95935993T patent/ES2148572T3/es not_active Expired - Lifetime
- 1995-10-20 WO PCT/FR1995/001388 patent/WO1996012727A1/fr not_active Ceased
- 1995-10-20 JP JP8513689A patent/JPH10507462A/ja active Pending
- 1995-10-20 DE DE69517191T patent/DE69517191T2/de not_active Expired - Fee Related
- 1995-10-20 PT PT95935993T patent/PT787135E/pt unknown
- 1995-10-20 US US08/817,907 patent/US6107284A/en not_active Expired - Fee Related
- 1995-10-20 EP EP95935993A patent/EP0787135B1/fr not_active Expired - Lifetime
- 1995-10-20 DK DK95935993T patent/DK0787135T3/da active
- 1995-10-20 AU AU38087/95A patent/AU705248B2/en not_active Ceased
2000
- 2000-08-08 GR GR20000401850T patent/GR3034155T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU3808795A (en)	1996-05-15
FR2725990A1 (fr)	1996-04-26
DE69517191T2 (de)	2001-02-15
AU705248B2 (en)	1999-05-20
FR2725990B1 (fr)	1997-01-10
ATE193297T1 (de)	2000-06-15
EP0787135B1 (fr)	2000-05-24
JPH10507462A (ja)	1998-07-21
NZ294878A (en)	1998-10-28
PT787135E (pt)	2000-11-30
DE69517191D1 (de)	2000-06-29
EP0787135A1 (fr)	1997-08-06
ES2148572T3 (es)	2000-10-16
US6107284A (en)	2000-08-22
GR3034155T3 (en)	2000-11-30
WO1996012727A1 (fr)	1996-05-02

Publication	Publication Date	Title
NO20002785D0 (no)	2000-05-31	Adamantanderivater
NO20002786D0 (no)	2000-05-31	Adamantanderivater
IL130931A0 (en)	2001-01-28	Small molecules useful in the treatment of inflammatory disease
SE9704546D0 (sv)	1997-12-05	Novel compounds
DK0703786T3 (da)	2002-05-27	Anvendelse af nona- og dekapeptider til fremstilling af et lægemiddel til behandling af AIDS
NO20002788D0 (no)	2000-05-31	Nye forbindelser
NO307968B1 (no)	2000-06-26	Pyrazolo- og pyrrolopyridiner og farmasøytisk blanding derav
ES2157993T3 (es)	2001-09-01	Benzoilguanidinas, su preparacion y su uso en medicamentos.
IL113450A (en)	1999-05-09	Process for the preparation of high solubility multicomponent inclusion complexes consisting of an acidic drug a cyclodextrin and a base and the complexes produced thereby
ES2148572T3 (es)	2000-10-16	Derivados hidrosolubles de epipodofilotoxina, su procedimiento de preparacion, su utilizacion a titulo de medicamento, y su utilizacion destinada a los tratamientos anticancerosos.
BR0207066A (pt)	2004-03-30	Derivados do 2h-1-benzopirano - processos para sua preparação e composições farmacêuticas a partir deles
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NO995685L (no)	1999-11-19	Nye glycosylerte ginkgolidderivater, anvendelse derav som medikamenter og farmasoeytiske blandinger
ATE215525T1 (de)	2002-04-15	Stabile derivate von ubiquinol, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung
HUT77868A (hu)	1998-09-28	Imidazopiridin-azolidinonok, ezeket tartalmazó gyógyszerkészítmények, alkalmazásuk és eljárás előállításukra
DE69804766D1 (de)	2002-05-16	Isoflavonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ES2163001T3 (es)	2002-01-16	Nuevos derivados de borneol, procedimiento para su preparacion y su utilizacion farmaceutica.
PT1064294E (pt)	2004-09-30	Derivados de antraciclina 5-imino-13-deoxi, suas utilizacoes e processos para a sua preparacao
NO974687L (no)	1997-12-11	Kondenserte <beta>-carboliner
GEP20053686B (en)	2005-12-12	Method For Obtaining an Isolated Extract of Plant Cyclamen Europaeum L. and Its Use