DK0795008T3 - Humane hypertrofe chondrocyt-cellelinjer - Google Patents

Humane hypertrofe chondrocyt-cellelinjer

Info

Publication number: DK0795008T3
Authority: DK; Denmark
Prior art keywords: cell lines; lines; chondrocyte cell; cell; hypertrophic chondrocyte
Prior art date: 1994-12-13

Application number

DK95934723T

Other languages

Danish (da)

English (en)

Inventor

Bradley Michael John Stringer

Original Assignee

Cellfactors Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-13

Filing date

1995-10-25

Publication date

2003-12-15

1995-10-25 Application filed by Cellfactors Plc filed Critical Cellfactors Plc

2003-12-15 Application granted granted Critical

2003-12-15 Publication of DK0795008T3 publication Critical patent/DK0795008T3/da

Links

210000003559 hypertrophic chondrocyte Anatomy 0.000 title 1
210000001612 chondrocyte Anatomy 0.000 abstract 3
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
230000002917 arthritic effect Effects 0.000 abstract 1
230000009286 beneficial effect Effects 0.000 abstract 1
229910052791 calcium Inorganic materials 0.000 abstract 1
239000011575 calcium Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940124597 therapeutic agent Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Rheumatology (AREA)
Veterinary Medicine (AREA)
Botany (AREA)
Public Health (AREA)
Dermatology (AREA)
Medicinal Chemistry (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Epidemiology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Developmental Biology & Embryology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Materials For Medical Uses (AREA)

DK95934723T 1994-12-13 1995-10-25 Humane hypertrofe chondrocyt-cellelinjer DK0795008T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9425071.9A GB9425071D0 (en)	1994-12-13	1994-12-13	Chondrocyte cell lines
PCT/GB1995/002497 WO1996018728A1 (en)	1994-12-13	1995-10-25	Chondrocyte cell-lines

Publications (1)

Publication Number	Publication Date
DK0795008T3 true DK0795008T3 (da)	2003-12-15

Family

ID=10765824

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95934723T DK0795008T3 (da)	1994-12-13	1995-10-25	Humane hypertrofe chondrocyt-cellelinjer

Country Status (15)

Country	Link
EP (2)	EP1142989A3 (cs)
JP (3)	JPH10510985A (cs)
KR (1)	KR980700410A (cs)
AT (1)	ATE248218T1 (cs)
AU (1)	AU3703795A (cs)
CA (1)	CA2207764A1 (cs)
CZ (1)	CZ182497A3 (cs)
DE (1)	DE69531627T2 (cs)
DK (1)	DK0795008T3 (cs)
ES (1)	ES2206518T3 (cs)
GB (1)	GB9425071D0 (cs)
HU (1)	HU221244B1 (cs)
MX (1)	MX9704296A (cs)
PT (1)	PT795008E (cs)
WO (1)	WO1996018728A1 (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1599793A (zh)	2001-12-07	2005-03-23	杰龙公司	人胚胎干细胞衍生的软骨细胞前体
JP2006289062A (ja) *	2005-03-18	2006-10-26	Pentax Corp	肥大化能を有する軟骨細胞と足場を用いた骨補填材料
US9029145B2 (en)	2010-04-08	2015-05-12	The University Court Of The University Of Edinburgh	Chondrogenic progenitor cells, protocol for derivation of cells and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994009118A1 (en) *	1992-10-13	1994-04-28	The General Hospital Corporation	Immortalized human chondrocytes

1994
- 1994-12-13 GB GBGB9425071.9A patent/GB9425071D0/en active Pending
1995
- 1995-10-25 EP EP01110823A patent/EP1142989A3/en not_active Withdrawn
- 1995-10-25 DE DE69531627T patent/DE69531627T2/de not_active Expired - Fee Related
- 1995-10-25 CZ CZ971824A patent/CZ182497A3/cs unknown
- 1995-10-25 JP JP8518391A patent/JPH10510985A/ja not_active Withdrawn
- 1995-10-25 CA CA002207764A patent/CA2207764A1/en not_active Abandoned
- 1995-10-25 HU HU9702182A patent/HU221244B1/hu not_active IP Right Cessation
- 1995-10-25 ES ES95934723T patent/ES2206518T3/es not_active Expired - Lifetime
- 1995-10-25 WO PCT/GB1995/002497 patent/WO1996018728A1/en not_active Ceased
- 1995-10-25 KR KR1019970703945A patent/KR980700410A/ko not_active Ceased
- 1995-10-25 AU AU37037/95A patent/AU3703795A/en not_active Abandoned
- 1995-10-25 AT AT95934723T patent/ATE248218T1/de not_active IP Right Cessation
- 1995-10-25 DK DK95934723T patent/DK0795008T3/da active
- 1995-10-25 MX MX9704296A patent/MX9704296A/es unknown
- 1995-10-25 PT PT95934723T patent/PT795008E/pt unknown
- 1995-10-25 EP EP95934723A patent/EP0795008B1/en not_active Expired - Lifetime
2002
- 2002-10-24 JP JP2002310323A patent/JP2003116533A/ja not_active Withdrawn
2005
- 2005-07-13 JP JP2005205003A patent/JP2005312996A/ja active Pending

Also Published As

Publication number	Publication date
DE69531627D1 (de)	2003-10-02
EP1142989A3 (en)	2001-11-21
GB9425071D0 (en)	1995-02-08
AU3703795A (en)	1996-07-03
EP1142989A2 (en)	2001-10-10
HUT77076A (hu)	1998-03-02
HU221244B1 (en)	2002-09-28
DE69531627T2 (de)	2004-06-17
EP0795008B1 (en)	2003-08-27
JP2003116533A (ja)	2003-04-22
JP2005312996A (ja)	2005-11-10
ES2206518T3 (es)	2004-05-16
CZ182497A3 (en)	1997-11-12
JPH10510985A (ja)	1998-10-27
MX9704296A (es)	1998-02-28
CA2207764A1 (en)	1996-06-20
EP0795008A1 (en)	1997-09-17
ATE248218T1 (de)	2003-09-15
PT795008E (pt)	2004-01-30
KR980700410A (ko)	1998-03-30
WO1996018728A1 (en)	1996-06-20

Publication	Publication Date	Title
ZA9810444B (en)	1999-06-24	Use of 9-deoxy-2',9-methano-3-oxa-4,5,6-trinor-3,7-(1',3'interphenylene)-13,14-dihydroprostaglandin F1 to treat peripheral vascular disease
ES2191102T3 (es)	2003-09-01	Heterociclos de peptidilo utiles en el tratamiento de las afecciones relacionadas con la trombina.
ATE180976T1 (de)	1999-06-15	Insizierbare lecithin gel
MY129189A (en)	2007-03-30	Prostaglandin agonists and their use to treat bone disorders
TR199701212T1 (xx)	1998-03-21	�drar� tutamama halinin tedavisi i�in alfa IL- agonistlerinin kullan�lmas�.
EP0896533A4 (en)	1999-04-28	PENTAFLUOROBENZEN SULPHONAMIDES AND ANALOGS
BG102425A (en)	1999-06-30	(methylsulphonyl)phenyl-2-(5h)-furanons as cyclooxygenase-2-inhibitors
ID29393A (id)	2001-08-30	Komposisi pengobatan kanker dan metoda penggunaan minyak-minyak esensil tanaman alamiah
PT998287E (pt)	2003-09-30	Utilizacao de levobupivacaina
BRPI0015533B8 (pt)	2021-05-25	enzima alfa-l-iduronidase humana recombinante, composição farmacêutica compreendendo a mesma e método para sua purificação
DE69530403D1 (de)	2003-05-22	Analogen des keratinozytenwachstumfaktors
EA200100184A1 (ru)	2001-10-22	Новые гидратные формы алендроната натрия, способы их получения и фармацевтические композиции
BR9609069A (pt)	1999-04-06	Indução de esterelidade masculina em plantas por expressão de níveis elevados de avidina
DE69631656D1 (de)	2004-04-01	Debromhymenialdisin und verwandte verbindungen zur behandlung von osteoarthritis
TR200003144T2 (tr)	2001-03-21	Tiyenopirimidinler.
BG105275A (en)	2001-11-30	Tan-1057 derivatives
DE69521122D1 (de)	2001-07-05	2,3,4,5-tetrahydro-1h-3-benzazepin säure-additions-salze
PT775135E (pt)	2003-10-31	Derivados de 3-azabiciclo(3.2.0)heptano substituidos em n uteis como neurolepticos
MY103210A (en)	1993-05-29	Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds.
TR200200278T2 (tr)	2002-06-21	Kalsilitik bileşimler
DK0795008T3 (da)	2003-12-15	Humane hypertrofe chondrocyt-cellelinjer
ATE330604T1 (de)	2006-07-15	Behandlung von manischen erkrankungen
ATE306278T1 (de)	2005-10-15	Behandlung von knochenleiden mit adrenomedullin
DE59605382D1 (de)	2000-07-13	Vorrichtung zur künstlichen Befruchtung von Sauen
EA200001157A3 (ru)	2001-08-27	Новые замещенные производные (дигидро)бензоксазина и (дигидро)бензотиазина, способ их получения и содержащие их фармацевтические композиции