DK0806408T3 - Antivirale forbindelser - Google Patents

Antivirale forbindelser

Info

Publication number
DK0806408T3
DK0806408T3 DK97303020T DK97303020T DK0806408T3 DK 0806408 T3 DK0806408 T3 DK 0806408T3 DK 97303020 T DK97303020 T DK 97303020T DK 97303020 T DK97303020 T DK 97303020T DK 0806408 T3 DK0806408 T3 DK 0806408T3
Authority
DK
Denmark
Prior art keywords
virus
antiviral compounds
cell
mammal
inhibited
Prior art date
Application number
DK97303020T
Other languages
Danish (da)
English (en)
Inventor
William Joseph Hornback
John Edwin Munroe
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0806408T3 publication Critical patent/DK0806408T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/84—Hydrazones having doubly-bound carbon atoms of hydrazone groups being part of rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/44—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK97303020T 1996-05-06 1997-05-02 Antivirale forbindelser DK0806408T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1687996P 1996-05-06 1996-05-06

Publications (1)

Publication Number Publication Date
DK0806408T3 true DK0806408T3 (da) 2001-01-02

Family

ID=21779504

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97303020T DK0806408T3 (da) 1996-05-06 1997-05-02 Antivirale forbindelser

Country Status (13)

Country Link
US (1) US6103922A (de)
EP (1) EP0806408B1 (de)
JP (1) JP2000510468A (de)
AT (1) ATE198070T1 (de)
AU (1) AU2752297A (de)
CA (1) CA2253405A1 (de)
DE (1) DE69703672T2 (de)
DK (1) DK0806408T3 (de)
ES (1) ES2152630T3 (de)
GR (1) GR3035556T3 (de)
PT (1) PT806408E (de)
SI (1) SI0806408T1 (de)
WO (1) WO1997041822A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2253502A1 (en) * 1996-05-06 1997-11-13 Stephen Warren Kaldor Anti-viral compounds
JP2000511514A (ja) 1996-05-06 2000-09-05 イーライ・リリー・アンド・カンパニー 抗ウイルス化合物
US6156924A (en) * 1996-05-06 2000-12-05 Eli Lilly And Company Anti-viral compounds
JP2000511886A (ja) * 1996-05-06 2000-09-12 イーライ・リリー・アンド・カンパニー 抗ウイルス方法
US6127422A (en) * 1996-05-06 2000-10-03 Eli Lilly And Company Anti-viral method
US6103923A (en) * 1996-05-06 2000-08-15 Eli Lilly And Company Anti-viral compounds
EP0811599B1 (de) 1996-05-06 2001-03-07 Eli Lilly And Company Antivirusverbindungen
CA2253405A1 (en) * 1996-05-06 1997-11-13 William Joseph Hornback Anti-viral compounds
US6096917A (en) * 1997-05-02 2000-08-01 Eli Lilly And Company Anti-viral compounds
US6175034B1 (en) 2000-04-10 2001-01-16 Eli Lilly And Company Anti-viral compounds
US6639177B2 (en) * 2001-03-29 2003-10-28 Gsi Lumonics Corporation Method and system for processing one or more microstructures of a multi-material device
US7312031B1 (en) 2002-12-06 2007-12-25 The Salk Institute For Biological Studies Alpha-complementation viral fusion assay

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2750405A (en) * 1952-06-18 1956-06-12 Hercules Powder Co Ltd Hydroxydehydroabietic acid and esters thereof
US2744100A (en) * 1952-12-13 1956-05-01 Hercules Powder Co Ltd Bromodehydroabietic acid derivatives
US2744102A (en) * 1952-12-13 1956-05-01 Hercules Powder Co Ltd Acetoxydehydroabietic acid derivatives
US2759014A (en) * 1953-04-06 1956-08-14 Searle & Co Derivatives of 9-oxo-octahydrophenan-threne-1-carboxylic acid
US2703809A (en) * 1953-07-31 1955-03-08 Hercules Powder Co Ltd 7-acetyl-1, 2, 3, 4, 4alpha, 9, 10, 10alpha-octahydro-1, 4alpha-dimethyl-9-oxo-1-phenhrenecarboxylic acid and esters thereof
US2750407A (en) * 1953-07-31 1956-06-12 Hercules Powder Co Ltd Substituted phenanthrenecarboxylic acid and esters thereof
US2767162A (en) * 1953-11-23 1956-10-16 Searle & Co Glycolyl derivatives of 1, 12-dimethylpolyhydrophenanthrene-1-carboxylic acid esters
US2750382A (en) * 1953-12-03 1956-06-12 Searle & Co Basic esters of 1, 12-dimethyl-6-alkoxy-1, 2, 3, 4, 9, 10, 11, 12-octahydrophenanthrene-1-carboxylic acids
US2753357A (en) * 1954-11-26 1956-07-03 Searle & Co Lactones of 1, 12-dimethyl-6, 10-dihydroxy-9-oxo-1, 2, 3, 4, 9, 10, 11, 12-octahydrophenanthrene-1-carboxylic acid
US2862955A (en) * 1955-08-17 1958-12-02 Searle & Co Esters of hydroxyacyl-9-oxodehydroabietic acid
US2854474A (en) * 1956-07-19 1958-09-30 Searle & Co 1,12-dimethyl-6-hydroxy-7-acyl-9-oxo-1,2,3,4,9,10,11,12-cotahydrophenan-threne-1-carboxylic acids and derivatives thereof
US2947778A (en) * 1958-09-23 1960-08-02 Searle & Co 1, 12-dimethyl-6-hydroxy-7-aroyl-1, 2, 3, 4, 9, 10, 11, 12-octahydrophenanthrene-1-car-boxylic acids, ethers and esters thereof
US3014957A (en) * 1959-01-23 1961-12-26 G D Searle & Co Inc 6-(substituted benzoyl) dehydroabietonitriles and derivatives
US3038930A (en) * 1960-08-12 1962-06-12 Searle & Co 1, 2, 3, 4, 4a, 9, 10, 10a-octahydro-7-hydroxy-6-methoxy-1, 4a-dimethyl-phenanthrene-1-(carboxylic acid/methanol)and corresponding esters
US3668223A (en) * 1970-08-19 1972-06-06 Merck & Co Inc 2-oxo-3-benzoxepins
US4333941A (en) * 1975-12-22 1982-06-08 The Dow Chemical Company Inhibition of enveloped viruses with phenyl ketones
GB1574019A (en) * 1977-01-14 1980-09-03 Joullie International Sa Therapeutically useful 3,4,5-trimethoxybenzene derivatives
US5015644A (en) * 1987-06-02 1991-05-14 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
US5116865A (en) * 1990-09-05 1992-05-26 Peters Richard H 15,16-seco-19-nor progestins
IL102548A (en) * 1991-08-02 1998-08-16 Medivir Ab Thiourea derivatives for use in the preparation of medicaments for the inhibition of hiv and the treatment of aids and some such novel compounds
NL1003010C2 (nl) * 1996-05-03 1997-11-06 Dsm Nv Werkwijze voor het omzetten van een geminaal gesubstitueerd cyclopentadieen.
EP0811599B1 (de) * 1996-05-06 2001-03-07 Eli Lilly And Company Antivirusverbindungen
JP2000511886A (ja) * 1996-05-06 2000-09-12 イーライ・リリー・アンド・カンパニー 抗ウイルス方法
CA2253405A1 (en) * 1996-05-06 1997-11-13 William Joseph Hornback Anti-viral compounds
AU2995597A (en) * 1996-05-06 1997-11-26 Eli Lilly And Company Anti-viral compounds
JP2000511514A (ja) * 1996-05-06 2000-09-05 イーライ・リリー・アンド・カンパニー 抗ウイルス化合物
DE69704229T2 (de) * 1996-05-06 2001-08-09 Eli Lilly And Co., Indianapolis Antivirusverbindungen

Also Published As

Publication number Publication date
SI0806408T1 (en) 2001-04-30
EP0806408B1 (de) 2000-12-13
AU2752297A (en) 1997-11-26
US6103922A (en) 2000-08-15
ATE198070T1 (de) 2000-12-15
CA2253405A1 (en) 1997-11-13
DE69703672T2 (de) 2001-05-17
DE69703672D1 (de) 2001-01-18
PT806408E (pt) 2001-04-30
WO1997041822A3 (en) 1998-05-14
GR3035556T3 (en) 2001-06-29
JP2000510468A (ja) 2000-08-15
WO1997041822A2 (en) 1997-11-13
ES2152630T3 (es) 2001-02-01
EP0806408A1 (de) 1997-11-12

Similar Documents

Publication Publication Date Title
EA200300023A1 (ru) 3'-ПРОЛЕКАРСТВА 2'-ДЕЗОКСИ-β-L-НУКЛЕОЗИДОВ
DE10399031I1 (de) Rekombinante Viren.
DK0811599T3 (da) Antivirale forbindelser
MY129773A (en) An attenuated japanese encephalitis virus adapted to vero cell and a japanese encephalitis vaccine
EP0806205A3 (de) Harnstoff-, Thioharnstoff- und Guanidinverbindungen und deren Verwendung als antivirale Mittel
ES530906A0 (es) Procedimiento de deteccion de la posicion de objetos paralelepipedicos identicos, almacenados sobre, al menos, una paleta
DE68911644D1 (de) Schutzdiode gegen Überstrom.
DK0806408T3 (da) Antivirale forbindelser
ES2159815T3 (es) Compuestos antivirales.
EP0806203A3 (de) Antivirale Zubereitungen
DK0806409T3 (da) Antivirale forbindelser
EP0811600A3 (de) Antivirusverbindungen
DK0806411T3 (da) Antivirale forbindelser
IT8920475V0 (it) Raccoglitore particolarmente per blocco di fogli.
FI914673L (fi) Peptider, som reagerar immunokemiskt med antikroppar mot hepatitis icke-a, icke-b-virus.
ITRM910039A1 (it) Siringa dotata di custodia protettuva anticontagio.