DK0806941T3 - Liposomalt antibakterielt præparat med lav fasthed - Google Patents
Liposomalt antibakterielt præparat med lav fasthedInfo
- Publication number
- DK0806941T3 DK0806941T3 DK95940928T DK95940928T DK0806941T3 DK 0806941 T3 DK0806941 T3 DK 0806941T3 DK 95940928 T DK95940928 T DK 95940928T DK 95940928 T DK95940928 T DK 95940928T DK 0806941 T3 DK0806941 T3 DK 0806941T3
- Authority
- DK
- Denmark
- Prior art keywords
- liposomal
- antibacterial preparation
- agent
- low firm
- firm
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Materials For Medical Uses (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/363,416 US5662929A (en) | 1994-12-23 | 1994-12-23 | Therapeutic liposomal formulation |
| PCT/CA1995/000713 WO1996019972A1 (en) | 1994-12-23 | 1995-12-22 | Low rigidity liposomal antibacterial composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0806941T3 true DK0806941T3 (da) | 2003-07-21 |
Family
ID=23430112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95940928T DK0806941T3 (da) | 1994-12-23 | 1995-12-22 | Liposomalt antibakterielt præparat med lav fasthed |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5662929A (da) |
| EP (1) | EP0806941B1 (da) |
| JP (1) | JP4523078B2 (da) |
| KR (1) | KR100438657B1 (da) |
| AT (1) | ATE235229T1 (da) |
| AU (1) | AU702463B2 (da) |
| BR (2) | BR9510423A (da) |
| CA (1) | CA2206296C (da) |
| DE (1) | DE69530124T2 (da) |
| DK (1) | DK0806941T3 (da) |
| ES (1) | ES2196092T3 (da) |
| NZ (1) | NZ297364A (da) |
| PT (1) | PT806941E (da) |
| WO (1) | WO1996019972A1 (da) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6443949B2 (en) * | 1997-03-13 | 2002-09-03 | Biocardia, Inc. | Method of drug delivery to interstitial regions of the myocardium |
| US6511477B2 (en) * | 1997-03-13 | 2003-01-28 | Biocardia, Inc. | Method of drug delivery to interstitial regions of the myocardium |
| US6054133A (en) * | 1997-07-10 | 2000-04-25 | The Regents Of The University Of California | Anti-microbial targeting for intracellular pathogens |
| US6613352B2 (en) * | 1999-04-13 | 2003-09-02 | Universite De Montreal | Low-rigidity liposomal formulation |
| US6365138B1 (en) * | 2000-04-07 | 2002-04-02 | The Regents Of The University Of California | Compositions for metabolic protection and repair of lips |
| EP1289570B1 (en) * | 2000-06-16 | 2008-09-10 | Sloan-Kettering Institute For Cancer Research | Liposomal encapsulation of alpha-emitters and uses thereof |
| DE122011100043I1 (de) | 2000-12-27 | 2011-12-15 | Gilead Sciences Inc | Inhalierbares aztreonam zur behandlung und vorbeugung von bakteriellen lungeninfektionen. |
| US7214364B2 (en) * | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| JP2005530704A (ja) * | 2002-03-05 | 2005-10-13 | トランセイブ, インク. | 細胞内感染を予防及び治療するための吸入システム |
| DE10214983A1 (de) * | 2002-04-04 | 2004-04-08 | TransMIT Gesellschaft für Technologietransfer mbH | Vernebelbare Liposomen und ihre Verwendung zur pulmonalen Applikation von Wirkstoffen |
| US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
| US7718189B2 (en) * | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| PT1581236E (pt) * | 2002-10-29 | 2013-12-24 | Insmed Inc | Libertação prolongada de anti-infecciosos |
| DE10255285A1 (de) * | 2002-11-26 | 2004-06-03 | Mcs Micro Carrier Systems Gmbh | Selbst formende Phospholipid-Gele |
| NZ546821A (en) * | 2003-10-15 | 2009-04-30 | Pari Pharma Gmbh | Liquid preparation containing tobramycin |
| US20050214224A1 (en) * | 2003-11-04 | 2005-09-29 | Nektar Therapeutics | Lipid formulations for spontaneous drug encapsulation |
| EP3067047B1 (en) | 2005-12-08 | 2022-04-20 | Insmed Incorporated | Lipid-based compositions of antiinfectives for treating pulmonary infections |
| WO2008137717A1 (en) | 2007-05-04 | 2008-11-13 | Transave, Inc. | Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
| US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
| WO2013009761A1 (en) | 2011-07-13 | 2013-01-17 | The Foundry, Llc | Methods and apparatus for delivering a therapeutic agent to nasopharyngeal mucosa targets |
| DE102009031274A1 (de) | 2009-06-30 | 2011-01-13 | Justus-Liebig-Universität Giessen | Liposomen zur pulmonalen Applikation |
| PL2852391T3 (pl) | 2012-05-21 | 2022-04-11 | Insmed Incorporated | Układy do leczenia infekcji płuc |
| US10124066B2 (en) | 2012-11-29 | 2018-11-13 | Insmed Incorporated | Stabilized vancomycin formulations |
| LT3466432T (lt) | 2014-05-15 | 2020-12-28 | Insmed Incorporated | Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti |
| CN106999419A (zh) | 2014-08-04 | 2017-08-01 | 佐尼奥尼制药股份有限公司 | 远程装载略微水溶性药物至脂质膜泡 |
| ES2574615B1 (es) * | 2014-12-19 | 2017-07-24 | Biopraxis Research Aie | Nanopartícula lipídica de tobramicina |
| WO2019070586A1 (en) * | 2017-10-02 | 2019-04-11 | Aridis Pharmaceuticals, Inc. | COMPOSITIONS AND METHODS FOR P. AERUGINOSA INFECTIONS |
| EP3773505B1 (en) | 2018-03-30 | 2026-04-29 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| JP7449275B2 (ja) | 2018-05-02 | 2024-03-13 | インスメッド インコーポレイテッド | リポソーム薬物製剤の製造方法 |
| CN117017999B (zh) * | 2023-09-20 | 2024-11-12 | 四川大学 | 一种夫西地酸磷脂复合物及其制备方法和用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4981692A (en) * | 1983-03-24 | 1991-01-01 | The Liposome Company, Inc. | Therapeutic treatment by intramammary infusion |
| US4753788A (en) * | 1985-01-31 | 1988-06-28 | Vestar Research Inc. | Method for preparing small vesicles using microemulsification |
| US4952405A (en) * | 1988-10-20 | 1990-08-28 | Liposome Technology, Inc. | Method of treating M. avium infection |
| US5006343A (en) * | 1988-12-29 | 1991-04-09 | Benson Bradley J | Pulmonary administration of pharmaceutically active substances |
| PT100486B (pt) * | 1992-05-14 | 1999-07-30 | Ineti Inst Nac Engenh E Tecnol | Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao |
| WO1994012155A1 (en) * | 1992-12-02 | 1994-06-09 | Vestar, Inc. | Antibiotic formulation and process |
-
1994
- 1994-12-23 US US08/363,416 patent/US5662929A/en not_active Expired - Lifetime
-
1995
- 1995-12-22 EP EP95940928A patent/EP0806941B1/en not_active Expired - Lifetime
- 1995-12-22 BR BR9510423-2A patent/BR9510423A/pt not_active IP Right Cessation
- 1995-12-22 ES ES95940928T patent/ES2196092T3/es not_active Expired - Lifetime
- 1995-12-22 DK DK95940928T patent/DK0806941T3/da active
- 1995-12-22 PT PT95940928T patent/PT806941E/pt unknown
- 1995-12-22 NZ NZ297364A patent/NZ297364A/xx not_active IP Right Cessation
- 1995-12-22 AU AU42510/96A patent/AU702463B2/en not_active Ceased
- 1995-12-22 AT AT95940928T patent/ATE235229T1/de active
- 1995-12-22 JP JP52009096A patent/JP4523078B2/ja not_active Expired - Fee Related
- 1995-12-22 KR KR1019970703952A patent/KR100438657B1/ko not_active Expired - Fee Related
- 1995-12-22 CA CA002206296A patent/CA2206296C/en not_active Expired - Fee Related
- 1995-12-22 DE DE69530124T patent/DE69530124T2/de not_active Expired - Lifetime
- 1995-12-22 WO PCT/CA1995/000713 patent/WO1996019972A1/en not_active Ceased
- 1995-12-22 BR BRPI9510423A patent/BRPI9510423B8/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE235229T1 (de) | 2003-04-15 |
| NZ297364A (en) | 2000-01-28 |
| AU702463B2 (en) | 1999-02-25 |
| MX9704679A (es) | 1998-07-31 |
| PT806941E (pt) | 2003-08-29 |
| BR9510423A (pt) | 2003-01-07 |
| DE69530124T2 (de) | 2004-02-05 |
| BRPI9510423B8 (pt) | 2019-11-05 |
| WO1996019972A1 (en) | 1996-07-04 |
| EP0806941A1 (en) | 1997-11-19 |
| AU4251096A (en) | 1996-07-19 |
| EP0806941B1 (en) | 2003-03-26 |
| KR980700062A (ko) | 1998-03-30 |
| DE69530124D1 (de) | 2003-04-30 |
| ES2196092T3 (es) | 2003-12-16 |
| CA2206296A1 (en) | 1996-07-04 |
| KR100438657B1 (ko) | 2004-08-18 |
| JPH10511363A (ja) | 1998-11-04 |
| JP4523078B2 (ja) | 2010-08-11 |
| CA2206296C (en) | 2007-05-22 |
| US5662929A (en) | 1997-09-02 |
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