DK0814788T3 - Forbedring af glucosetolerance - Google Patents

Forbedring af glucosetolerance

Info

Publication number: DK0814788T3
Authority: DK; Denmark
Prior art keywords: glucose tolerance; improving glucose; improving; monohydrate; cyclobutyl
Prior art date: 1994-02-03

Application number

DK95909382T

Other languages

Danish (da)

English (en)

Inventor

Ramon Vargas

Original Assignee

Boots Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-02-03

Filing date

1995-02-03

Publication date

2001-11-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22703362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0814788(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-02-03 Application filed by Boots Pharma Inc filed Critical Boots Pharma Inc

2001-11-19 Application granted granted Critical

2001-11-19 Publication of DK0814788T3 publication Critical patent/DK0814788T3/da

Links

WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 2
239000008103 glucose Substances 0.000 title abstract 2
UWAOJIWUVCMBAZ-UHFFFAOYSA-N [1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl]-dimethylazanium;chloride Chemical compound Cl.C=1C=C(Cl)C=CC=1C1(C(N(C)C)CC(C)C)CCC1 UWAOJIWUVCMBAZ-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
150000004682 monohydrates Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Polyesters Or Polycarbonates (AREA)
Lubricants (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Materials For Medical Uses (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK95909382T 1994-02-03 1995-02-03 Forbedring af glucosetolerance DK0814788T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/190,924 US5459164A (en)	1994-02-03	1994-02-03	Medical treatment
PCT/US1995/001190 WO1995020949A1 (en)	1994-02-03	1995-02-03	Improving glucose tolerance

Publications (1)

Publication Number	Publication Date
DK0814788T3 true DK0814788T3 (da)	2001-11-19

Family

ID=22703362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95909382T DK0814788T3 (da)	1994-02-03	1995-02-03	Forbedring af glucosetolerance

Country Status (17)

Country	Link
US (2)	US5459164A (cs)
EP (1)	EP0814788B1 (cs)
JP (1)	JPH10503166A (cs)
KR (1)	KR100339874B1 (cs)
CN (1)	CN1070698C (cs)
AT (1)	ATE205390T1 (cs)
AU (1)	AU694761B2 (cs)
CA (1)	CA2182620C (cs)
DE (1)	DE69522716T2 (cs)
DK (1)	DK0814788T3 (cs)
ES (1)	ES2166817T3 (cs)
IL (1)	IL112515A (cs)
PH (1)	PH31220A (cs)
PT (1)	PT814788E (cs)
TW (1)	TW314466B (cs)
WO (1)	WO1995020949A1 (cs)
ZA (1)	ZA95814B (cs)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9619757D0 (en) *	1996-09-21	1996-11-06	Knoll Ag	Chemical process
GB9619961D0 (en) *	1996-09-25	1996-11-13	Knoll Ag	Medical treatment
GB9619962D0 (en) *	1996-09-25	1996-11-13	Knoll Ag	Medical treatment
GB9727131D0 (en)	1997-12-24	1998-02-25	Knoll Ag	Therapeutic agents
US6974838B2 (en) *	1998-08-24	2005-12-13	Sepracor Inc.	Methods of treating or preventing pain using sibutramine metabolites
US6476078B2 (en) *	1999-08-11	2002-11-05	Sepracor, Inc.	Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6339106B1 (en)	1999-08-11	2002-01-15	Sepracor, Inc.	Methods and compositions for the treatment and prevention of sexual dysfunction
US6331571B1 (en)	1998-08-24	2001-12-18	Sepracor, Inc.	Methods of treating and preventing attention deficit disorders
US6696495B2 (en) *	1998-12-02	2004-02-24	Snowden Pharmaceuticals, Llc	Treatment of disorders secondary to organic impairments
US6323242B1 (en)	1998-12-02	2001-11-27	Peter Sterling Mueller	Treatment of disorders secondary to organic impairments
BG65170B1 (bg) *	1999-03-17	2007-05-31	Knoll Gmbh	Използване на n-заместени производни на 1-[1-(4-хлорофенил)циклобутил]-3-метилбутиламин за производство на лекарство за лечение на разстройства при храненето
AU3895400A (en) *	1999-03-19	2000-10-09	Knoll Pharmaceutical Company	Control of metabolism
US6372797B1 (en)	1999-03-19	2002-04-16	Knoll Pharmaceutical Company	Treatment of menstrual function
CA2367022A1 (en) *	1999-03-19	2000-09-28	Knoll Pharmaceutical Company	Method of treating sleep apnoea
US6365632B1 (en)	1999-03-19	2002-04-02	Knoll Pharmaceuticals Company	Treatment of orthostatic hypotension
AU3894500A (en) *	1999-03-19	2000-10-09	Knoll Pharmaceutical Company	Prevention of cardiovascular disease
PL351958A1 (en) *	1999-03-19	2003-07-14	Knoll Gmbh	Treatment of some tumours associated with gain in weight
CA2366660A1 (en) *	1999-03-19	2000-09-28	Carl M. Mendel	Treatment of osteoarthritis
US6552087B1 (en)	1999-03-19	2003-04-22	Abbott Gmbh & Co. Kg	Therapeutic agent comprising (+)-sibutramine
MXPA01009467A (es) *	1999-03-19	2004-03-19	Knoll Gmbh	Metodo para controlar el aumento de peso asociado con farmacos terapeuticos.
WO2000056315A1 (en) *	1999-03-19	2000-09-28	Knoll Pharmaceutical Company	Treatment of pain
WO2000056321A1 (en)	1999-03-19	2000-09-28	Knoll Pharmaceutical Company	Treatment of hyperactivity disorders
AU3895300A (en) *	1999-03-19	2000-10-09	Knoll Pharmaceutical Company	Treatment of chronic fatigue syndrome
JP2002539250A (ja) *	1999-03-19	2002-11-19	クノール・ゲー・エム・ベー・ハー	肺高血圧症の治療
WO2000056309A1 (en) *	1999-03-19	2000-09-28	Knoll Pharmaceutical Company	Method of treating sexual dysfunction
CA2368416A1 (en) *	1999-03-19	2000-09-28	Knoll Gmbh	Treatment of gallstones
US6803387B1 (en)	1999-03-19	2004-10-12	Abbott Gmbh & Co. Kg	Treatment of neuropathic pain or fibromyalgia
GB9914744D0 (en) *	1999-06-24	1999-08-25	Knoll Ag	Therapeutic agents
US6399826B1 (en)	1999-08-11	2002-06-04	Sepracor Inc.	Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
GB9926251D0 (en) *	1999-11-06	2000-01-12	Knoll Ag	Pharmaceutical formulation
US6232347B1 (en)	2000-03-17	2001-05-15	Knoll Pharmaceutical Company	Treatment of osteoarthritis
WO2002083631A1 (en) *	2001-04-13	2002-10-24	Sepracor Inc.	Methods of preparing didesmethylsibutramine and other sibutramine derivatives
US6602911B2 (en)	2001-11-05	2003-08-05	Cypress Bioscience, Inc.	Methods of treating fibromyalgia
US20040034101A1 (en) *	2001-11-05	2004-02-19	Cypress Bioscience, Inc.	Treatment and prevention of depression secondary to pain (DSP)
HRP20050307A2 (en) *	2002-10-05	2006-12-31	Hanmi Pharm. Co. Ltd.	Pharmaceutical composition comprising crystalline sibutramine methanesulfonate hemihydrate
US20050131074A1 (en) *	2003-08-04	2005-06-16	Beckman Kristen M.	Methods for treating metabolic syndrome
US7432398B2 (en)	2005-01-06	2008-10-07	Cj Corporation	Inorganic acid salts of sibutramine
KR100627687B1 (ko) *	2005-04-20	2006-09-25	주식회사 씨티씨바이오	시부트라민 유리염기 함유 조성물 및 이의 제조방법
US7994220B2 (en) *	2005-09-28	2011-08-09	Cypress Bioscience, Inc.	Milnacipran for the long-term treatment of fibromyalgia syndrome
AU2007322477A1 (en) *	2006-11-22	2008-05-29	Sk Chemicals Co., Ltd.	Inclusion complex of sibutramine and beta-cyclodextrin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE52768B1 (en) *	1981-04-06	1988-02-17	Boots Co Ltd	1-arylcyclobutylalkylamine compounds useful as therapeutic agents
GB8531071D0 (en) *	1985-12-17	1986-01-29	Boots Co Plc	Therapeutic compound
GB8704777D0 (en) *	1987-02-28	1987-04-01	Boots Co Plc	Medical treatment
ES2058272T3 (es) *	1987-05-04	1994-11-01	Lilly Co Eli	Fluoxetina util para el tratamiento de la diabetes.
JP2675573B2 (ja) *	1988-03-31	1997-11-12	科研製薬株式会社	脳機能改善剤
IE61928B1 (en) *	1988-11-29	1994-11-30	Boots Co Plc	Treatment of obesity

1994
- 1994-02-03 US US08/190,924 patent/US5459164A/en not_active Expired - Lifetime
1995
- 1995-02-01 IL IL11251595A patent/IL112515A/xx active IP Right Grant
- 1995-02-01 PH PH49876A patent/PH31220A/en unknown
- 1995-02-02 ZA ZA95814A patent/ZA95814B/xx unknown
- 1995-02-03 AU AU17362/95A patent/AU694761B2/en not_active Ceased
- 1995-02-03 ES ES95909382T patent/ES2166817T3/es not_active Expired - Lifetime
- 1995-02-03 AT AT95909382T patent/ATE205390T1/de not_active IP Right Cessation
- 1995-02-03 EP EP95909382A patent/EP0814788B1/en not_active Expired - Lifetime
- 1995-02-03 JP JP7520676A patent/JPH10503166A/ja active Pending
- 1995-02-03 CN CN95192226A patent/CN1070698C/zh not_active Expired - Fee Related
- 1995-02-03 PT PT95909382T patent/PT814788E/pt unknown
- 1995-02-03 KR KR1019960704203A patent/KR100339874B1/ko not_active Expired - Fee Related
- 1995-02-03 DK DK95909382T patent/DK0814788T3/da active
- 1995-02-03 DE DE69522716T patent/DE69522716T2/de not_active Expired - Lifetime
- 1995-02-03 WO PCT/US1995/001190 patent/WO1995020949A1/en not_active Ceased
- 1995-02-03 CA CA002182620A patent/CA2182620C/en not_active Expired - Fee Related
- 1995-03-02 TW TW084101992A patent/TW314466B/zh not_active IP Right Cessation
1997
- 1997-03-04 US US08/696,984 patent/US5942549A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
TW314466B (cs)	1997-09-01
PH31220A (en)	1998-05-05
CA2182620A1 (en)	1995-08-10
IL112515A0 (en)	1995-12-08
EP0814788A4 (en)	1999-05-06
CN1144479A (zh)	1997-03-05
KR100339874B1 (ko)	2002-11-22
ES2166817T3 (es)	2002-05-01
US5942549A (en)	1999-08-24
ZA95814B (en)	1995-08-03
US5459164A (en)	1995-10-17
IL112515A (en)	2000-07-26
JPH10503166A (ja)	1998-03-24
AU1736295A (en)	1995-08-21
ATE205390T1 (de)	2001-09-15
CA2182620C (en)	2007-01-16
PT814788E (pt)	2002-03-28
DE69522716D1 (de)	2001-10-18
CN1070698C (zh)	2001-09-12
DE69522716T2 (de)	2002-05-29
EP0814788B1 (en)	2001-09-12
AU694761B2 (en)	1998-07-30
EP0814788A1 (en)	1998-01-07
WO1995020949A1 (en)	1995-08-10

Publication	Publication Date	Title
DE69522716D1 (de)	2001-10-18	Verbesserung der glukosetoleranz
CA2266401A1 (en)	1998-03-26	Use of sibutramine analogues to prevent the development of diabetes
BG103249A (bg)	1999-09-30	Използване на сибутраминови аналози за понижаваненивата на липидите
CA2367666A1 (en)	2000-09-21	Method of treating eating disorders
KR960007592A (ko)	1996-03-22	신규한 피롤로카바졸
BG103278A (en)	2000-01-31	Medicamentous treatment
WO2000056315A8 (en)	2001-06-21	Treatment of pain
KR920016089A (ko)	1992-09-24	제i형 당뇨병의 치료방법
CA2022653A1 (en)	1991-02-06	Dampening solution for lithographic printing
KR950016735A (ko)	1995-07-20	터너 증후군의 억제 방법
DK1169029T3 (da)	2005-08-29	Anvendelse af sibutramin eller et derivat deraf til behandling af sövnforstyrrelser
EP1132087A4 (en)	2002-06-26	REMEDIES FOR POLYKYSTIC OVARY SYNDROME
ATE282608T1 (de)	2004-12-15	Chinoxalindionen
HK1045254A1 (zh)	2002-11-22	降低血小板黏性的处理方法
HK1044702A1 (zh)	2002-11-01	骨关节炎的治疗方法
PT86610A (pt)	1988-02-01	Process for the preparation of a fungicidal compound containing 1-aminoethyl-3-aryl-4-cyano-pyrroles
CA2138308A1 (en)	1995-06-19	Preparation of hexahydroazepinones and hexahydroazepinoles
KR950000704A (ko)	1995-01-03	로라카베프 하이드로클로라이드 c_1-c_3 알콜 용매화물 및 그의 용도
MXPA01009465A (es)	2004-03-19	Perdida de peso despues del embarazo.
DK0698601T3 (da)	1999-07-19	Fremgangsmåde til fremstilling af (-)-N-methyl-N-4-(4-phenyl-4-acetylaminopiperidin-1-yl)-2-(3,4-dichlorphenyl)butylbenzami
CA2388176A1 (en)	2001-05-10	Therapeutic agent for eating disorders
MXPA01009468A (es)	2004-03-19	Tratamiento de hipertension pulmonar.
BG106000A (en)	2002-06-28	Treatment of hiatial hernia
MXPA01009462A (es)	2004-03-19	Tratamiento de calculos biliares.
TH35673A (th)	1999-11-05	สารประกอบซับสทิทิวเทด อิมิดาโซล ชนิดใหม่