DK0814813T3 - Anvendelse af penciclovir til behandling af human herpesvirus-8 - Google Patents

Anvendelse af penciclovir til behandling af human herpesvirus-8

Info

Publication number: DK0814813T3
Authority: DK; Denmark
Prior art keywords: treatment; penciclovir; herpes virus; human herpes; bioprecursor
Prior art date: 1995-03-07

Application number

DK96907360T

Other languages

English (en)

Inventor

Klaus Max Esser

Hodge Richard Anthony Vere

Original Assignee

Novartis Int Pharm Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-07

Filing date

1996-03-05

Publication date

2004-03-22

1996-03-05 Application filed by Novartis Int Pharm Ltd filed Critical Novartis Int Pharm Ltd

2004-03-22 Application granted granted Critical

2004-03-22 Publication of DK0814813T3 publication Critical patent/DK0814813T3/da

Links

238000011282 treatment Methods 0.000 title abstract 2
241001502974 Human gammaherpesvirus 8 Species 0.000 title 1
JNTOCHDNEULJHD-UHFFFAOYSA-N Penciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(CCC(CO)CO)C=N2 JNTOCHDNEULJHD-UHFFFAOYSA-N 0.000 title 1
229960001179 penciclovir Drugs 0.000 title 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
206010066435 human herpesvirus 8 infection Diseases 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
-1 phosphate ester Chemical class 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Transplantation (AREA)
Biotechnology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK96907360T 1995-03-07 1996-03-05 Anvendelse af penciclovir til behandling af human herpesvirus-8 DK0814813T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9504497.0A GB9504497D0 (en)	1995-03-07	1995-03-07	Pharmaceuticals
PCT/EP1996/000933 WO1996027378A2 (en)	1995-03-07	1996-03-05	Use of penciclovir for the treatment of human herpes-virus-8

Publications (1)

Publication Number	Publication Date
DK0814813T3 true DK0814813T3 (da)	2004-03-22

Family

ID=10770731

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96907360T DK0814813T3 (da)	1995-03-07	1996-03-05	Anvendelse af penciclovir til behandling af human herpesvirus-8

Country Status (22)

Country	Link
US (1)	US6489330B1 (da)
EP (1)	EP0814813B1 (da)
JP (2)	JPH11501625A (da)
KR (1)	KR19980702833A (da)
CN (1)	CN1138545C (da)
AT (1)	ATE254919T1 (da)
AU (1)	AU701739B2 (da)
BR (1)	BR9607663A (da)
CA (1)	CA2214406C (da)
CY (1)	CY2525B1 (da)
CZ (1)	CZ293470B6 (da)
DE (1)	DE69630876T2 (da)
DK (1)	DK0814813T3 (da)
ES (1)	ES2211949T3 (da)
GB (1)	GB9504497D0 (da)
HU (1)	HU226005B1 (da)
NO (1)	NO317733B1 (da)
NZ (1)	NZ303951A (da)
PT (1)	PT814813E (da)
TR (1)	TR199700921T1 (da)
WO (1)	WO1996027378A2 (da)
ZA (1)	ZA961795B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2010503710A (ja)	2006-09-18	2010-02-04	ラプトールファーマシューティカルインコーポレイテッド	受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
EP2274042A4 (en) *	2008-04-11	2012-03-14	Epiphany Biosciences Inc	TREATMENT AND / OR PREVENTION OF MULTIPLE SCLEROSIS
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0141927B1 (en) *	1983-08-18	1991-10-30	Beecham Group Plc	Antiviral guanine derivatives
EP0182024B1 (en) *	1984-09-20	1991-04-03	Beecham Group Plc	Purine derivatives and their pharmaceutical use
EP0216459B1 (en) *	1985-07-27	1990-05-16	Beecham Group Plc	9-substituted guanine monohydrates
CA2042931A1 (en)	1990-05-24	1991-11-25	Robert Zahler	Fluorinated bis (hydroxymethyl) cyclobutyl purines and pyrimidines
GB9015051D0 (en)	1990-07-07	1990-08-29	Beecham Group Plc	Pharmaceutical treatment

1995
- 1995-03-07 GB GBGB9504497.0A patent/GB9504497D0/en active Pending
1996
- 1996-03-05 CA CA2214406A patent/CA2214406C/en not_active Expired - Fee Related
- 1996-03-05 TR TR97/00921T patent/TR199700921T1/xx unknown
- 1996-03-05 AT AT96907360T patent/ATE254919T1/de not_active IP Right Cessation
- 1996-03-05 NZ NZ303951A patent/NZ303951A/xx not_active IP Right Cessation
- 1996-03-05 JP JP8526607A patent/JPH11501625A/ja not_active Withdrawn
- 1996-03-05 CZ CZ19972831A patent/CZ293470B6/cs not_active IP Right Cessation
- 1996-03-05 DK DK96907360T patent/DK0814813T3/da active
- 1996-03-05 BR BR9607663A patent/BR9607663A/pt not_active Application Discontinuation
- 1996-03-05 AU AU51022/96A patent/AU701739B2/en not_active Ceased
- 1996-03-05 DE DE69630876T patent/DE69630876T2/de not_active Expired - Fee Related
- 1996-03-05 ZA ZA961795A patent/ZA961795B/xx unknown
- 1996-03-05 WO PCT/EP1996/000933 patent/WO1996027378A2/en not_active Ceased
- 1996-03-05 KR KR1019970706240A patent/KR19980702833A/ko not_active Ceased
- 1996-03-05 HU HU9800272A patent/HU226005B1/hu not_active IP Right Cessation
- 1996-03-05 CN CNB961937939A patent/CN1138545C/zh not_active Expired - Fee Related
- 1996-03-05 ES ES96907360T patent/ES2211949T3/es not_active Expired - Lifetime
- 1996-03-05 PT PT96907360T patent/PT814813E/pt unknown
- 1996-03-05 EP EP96907360A patent/EP0814813B1/en not_active Expired - Lifetime
1997
- 1997-09-05 NO NO19974101A patent/NO317733B1/no not_active IP Right Cessation
1999
- 1999-12-29 US US09/473,888 patent/US6489330B1/en not_active Expired - Lifetime
2005
- 2005-05-26 CY CY0500032A patent/CY2525B1/xx unknown
2007
- 2007-08-08 JP JP2007206799A patent/JP2007297412A/ja active Pending

Also Published As

Publication number	Publication date
CZ293470B6 (cs)	2004-05-12
KR19980702833A (ko)	1998-08-05
NO974101D0 (no)	1997-09-05
HUP9800272A3 (en)	2000-12-28
CA2214406C (en)	2010-12-21
HUP9800272A2 (hu)	2000-05-28
NO317733B1 (no)	2004-12-13
DE69630876D1 (de)	2004-01-08
JPH11501625A (ja)	1999-02-09
TR199700921T1 (xx)	1998-02-21
EP0814813A2 (en)	1998-01-07
ATE254919T1 (de)	2003-12-15
HK1004373A1 (en)	1998-11-27
GB9504497D0 (en)	1995-04-26
HU226005B1 (en)	2008-02-28
EP0814813B1 (en)	2003-11-26
WO1996027378A3 (en)	1997-01-16
BR9607663A (pt)	1998-06-16
CN1183722A (zh)	1998-06-03
MX9706759A (es)	1997-11-29
CN1138545C (zh)	2004-02-18
US6489330B1 (en)	2002-12-03
NZ303951A (en)	1999-07-29
PT814813E (pt)	2004-04-30
CY2525B1 (en)	2006-02-08
ES2211949T3 (es)	2004-07-16
CA2214406A1 (en)	1996-09-12
JP2007297412A (ja)	2007-11-15
ZA961795B (en)	1996-11-25
AU5102296A (en)	1996-09-23
WO1996027378A2 (en)	1996-09-12
CZ283197A3 (cs)	1998-02-18
NO974101L (no)	1997-09-05
DE69630876T2 (de)	2004-09-02
AU701739B2 (en)	1999-02-04

Publication	Publication Date	Title
FI905475A0 (fi)	1990-11-05	Menetelmä farmaseuttisesti vaikuttavan puriinijohdannaisen valmistamiseksi
PT736029E (pt)	2006-05-31	Sulfamatos de pseudofructopiranose anticonvulsivos
ES2111352T3 (es)	1998-03-01	Uso de diester fosfato para el tratamiento de enfermedades retinianas.
SE0004101D0 (sv)	2000-11-09	New use
YU6396A (sh)	1999-06-15	Kombinacija inhibitora hiv proteaze sa drugim jedinjenjima za terapiju hiv infekcija
MX9806229A (es)	1998-11-30	Derivados de benzo(c)quinolicina, su preparacion y uso como inhibidores de la 5alfa-reductasas.
DE69019404D1 (de)	1995-06-22	Derivate von Penciclovir zur Behandlung von Hepatitis-B-Infektionen.
NO974101D0 (no)	1997-09-05	Anvendelse av penciclovir for behandling av human herpes virus-8
DE10299023I2 (de)	2010-05-06	Antineoplastisch wirkender und den antineoplastischen effekt verstärkender wirkstoff
IL111138A (en)	1997-04-15	Pharmaceutical compositions comprising penciclovir and/or its bioprecursor and/or its derivatives for the treatment and prophylaxis of post-herpetic neuralgia
DE69429447D1 (de)	2002-01-24	Verwendung von 2-aminopurinderivaten zur behandlung und prophylaxe der menschlichen herpesvirus 7 infektionen
AP9801235A0 (en)	1999-11-07	Erythromycin derivatives.
CA2207503A1 (en)	1996-06-20	Use of aminopurine antiviral agents for the treatment and prophylaxis of latent herpesvirus infections
TR199900013T2 (xx)	1999-04-21	Yeni bile�ikler.
DK0728001T3 (da)	2002-04-15	Anvendelse af 2-aminopurinderivater til behandling og forebyggelse af humant herpesvirus 6-infektioner
ES2131331T3 (es)	1999-07-16	Uso de benzotiofenos para la preparacion de un medicamento para reducir la formacion de cicatrices en la curacion de heridas.