DK0816377T3 - Peptider, som binder sig til prothrombin og thrombin - Google Patents
Peptider, som binder sig til prothrombin og thrombinInfo
- Publication number
- DK0816377T3 DK0816377T3 DK97109744T DK97109744T DK0816377T3 DK 0816377 T3 DK0816377 T3 DK 0816377T3 DK 97109744 T DK97109744 T DK 97109744T DK 97109744 T DK97109744 T DK 97109744T DK 0816377 T3 DK0816377 T3 DK 0816377T3
- Authority
- DK
- Denmark
- Prior art keywords
- leu
- gly
- peptides
- thrombin
- tyr
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000190 Thrombin Proteins 0.000 title abstract 3
- 229960004072 thrombin Drugs 0.000 title abstract 3
- 108010094028 Prothrombin Proteins 0.000 title abstract 2
- 102100027378 Prothrombin Human genes 0.000 title abstract 2
- 229940039716 prothrombin Drugs 0.000 title abstract 2
- FKYQEVBRZSFAMJ-QWRGUYRKSA-N Gly-Ser-Tyr Chemical compound NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 FKYQEVBRZSFAMJ-QWRGUYRKSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6429—Thrombin (3.4.21.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/672,805 US5831003A (en) | 1996-06-28 | 1996-06-28 | Peptides which bind to prothrombin and thrombin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0816377T3 true DK0816377T3 (da) | 2002-07-22 |
Family
ID=24700072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97109744T DK0816377T3 (da) | 1996-06-28 | 1997-06-16 | Peptider, som binder sig til prothrombin og thrombin |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5831003A (fr) |
| EP (1) | EP0816377B1 (fr) |
| JP (1) | JP3978258B2 (fr) |
| AT (1) | ATE215964T1 (fr) |
| AU (1) | AU712575B2 (fr) |
| CA (1) | CA2206663A1 (fr) |
| DE (1) | DE69711765T2 (fr) |
| DK (1) | DK0816377T3 (fr) |
| ES (1) | ES2175218T3 (fr) |
| PT (1) | PT816377E (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6462180B1 (en) * | 1999-11-24 | 2002-10-08 | Bayer Corporation | Method of preparing α-1 proteinase inhibitor |
| NZ526940A (en) | 2000-12-14 | 2005-06-24 | Bayer Healthcare Llc | Method of preparing alpha-1 proteinase inhibitor |
| GB0211849D0 (en) * | 2002-05-23 | 2002-07-03 | Mok Kenneth H | Improvments to retro-inverso isomers |
| FR2884418B1 (fr) * | 2005-04-15 | 2008-11-21 | Soc Extraction Principes Actif | Utilisation d'un peptide comme principe actif amincissant |
| JP5564249B2 (ja) | 2006-06-23 | 2014-07-30 | アレシア・バイオセラピューティクス・インコーポレーテッド | 癌に関与するポリヌクレオチド配列およびポリペプチド配列 |
| AU2009321508B2 (en) | 2008-11-03 | 2015-03-12 | Adc Therapeutics Sa | Antibodies that specifically block the biological activity of a tumor antigen |
| US8945895B2 (en) | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| CN106146664B (zh) | 2011-03-31 | 2021-09-07 | Adc治疗股份有限公司 | 针对肾相关抗原1的抗体及其抗原结合片段 |
| CA3115623A1 (en) | 2012-01-09 | 2013-07-18 | Adc Therapeutics Sa | Method for treating breast cancer |
| ES2791982T3 (es) * | 2015-02-25 | 2020-11-06 | Omrix Biopharmaceuticals Ltd | Método para purificar y cuantificar la trombina y sus polipéptidos de degradación |
| CA2976875A1 (fr) | 2015-02-25 | 2016-09-01 | Omrix Biopharmaceuticals Ltd. | Procede pour purifier et quantifier la thrombine et ses polypeptides de degradation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341032C (fr) * | 1987-01-23 | 2000-06-20 | John L. Krstenansky | Peptides anti-coagulants |
| US5367060A (en) * | 1991-05-24 | 1994-11-22 | Genentech, Inc. | Structure, production and use of heregulin |
-
1996
- 1996-06-28 US US08/672,805 patent/US5831003A/en not_active Expired - Lifetime
-
1997
- 1997-06-16 PT PT97109744T patent/PT816377E/pt unknown
- 1997-06-16 AT AT97109744T patent/ATE215964T1/de active
- 1997-06-16 DK DK97109744T patent/DK0816377T3/da active
- 1997-06-16 EP EP97109744A patent/EP0816377B1/fr not_active Expired - Lifetime
- 1997-06-16 ES ES97109744T patent/ES2175218T3/es not_active Expired - Lifetime
- 1997-06-16 DE DE69711765T patent/DE69711765T2/de not_active Expired - Lifetime
- 1997-06-23 AU AU26220/97A patent/AU712575B2/en not_active Ceased
- 1997-06-24 JP JP18189597A patent/JP3978258B2/ja not_active Expired - Fee Related
- 1997-06-25 CA CA002206663A patent/CA2206663A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US5831003A (en) | 1998-11-03 |
| JPH1075778A (ja) | 1998-03-24 |
| ES2175218T3 (es) | 2002-11-16 |
| AU712575B2 (en) | 1999-11-11 |
| AU2622097A (en) | 1998-01-15 |
| PT816377E (pt) | 2002-08-30 |
| ATE215964T1 (de) | 2002-04-15 |
| EP0816377B1 (fr) | 2002-04-10 |
| DE69711765D1 (de) | 2002-05-16 |
| DE69711765T2 (de) | 2002-10-02 |
| EP0816377A3 (fr) | 1998-07-15 |
| EP0816377A2 (fr) | 1998-01-07 |
| JP3978258B2 (ja) | 2007-09-19 |
| CA2206663A1 (fr) | 1997-12-28 |
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