DK0826657T3 - Hidtil ukendte forbindelser til modulering af hormonreceptorer, sammensætninger, der omfatter dem, og deres anvendelse i terapi - Google Patents

Hidtil ukendte forbindelser til modulering af hormonreceptorer, sammensætninger, der omfatter dem, og deres anvendelse i terapi

Info

Publication number: DK0826657T3
Authority: DK; Denmark
Prior art keywords: therapy; compositions; new compounds; hormone receptors; modulating hormone
Prior art date: 1996-09-02

Application number

DK97401999T

Other languages

English (en)

Inventor

Etienne Thoreau

Braham Shroot

Original Assignee

Galderma Rech Dermatologique

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-02

Filing date

1997-08-27

Publication date

2001-10-22

1997-08-27 Application filed by Galderma Rech Dermatologique filed Critical Galderma Rech Dermatologique

2001-10-22 Application granted granted Critical

2001-10-22 Publication of DK0826657T3 publication Critical patent/DK0826657T3/da

Links

150000001875 compounds Chemical class 0.000 title 1
108091008039 hormone receptors Proteins 0.000 title 1
239000000203 mixture Substances 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
101100295738 Gallus gallus COR3 gene Proteins 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
IPZJQDSFZGZEOY-UHFFFAOYSA-N dimethylmethylene Chemical group C[C]C IPZJQDSFZGZEOY-UHFFFAOYSA-N 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
150000002790 naphthalenes Chemical class 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Biotechnology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)
Furan Compounds (AREA)
Pyrane Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK97401999T 1996-09-02 1997-08-27 Hidtil ukendte forbindelser til modulering af hormonreceptorer, sammensætninger, der omfatter dem, og deres anvendelse i terapi DK0826657T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9610686A FR2752837B1 (fr)	1996-09-02	1996-09-02	Nouveaux composes modulateurs des recepteurs hormonaux, les compositions les comprenant et leur utilisation en therapie

Publications (1)

Publication Number	Publication Date
DK0826657T3 true DK0826657T3 (da)	2001-10-22

Family

ID=9495359

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97401999T DK0826657T3 (da)	1996-09-02	1997-08-27	Hidtil ukendte forbindelser til modulering af hormonreceptorer, sammensætninger, der omfatter dem, og deres anvendelse i terapi

Country Status (12)

Country	Link
US (1)	US5910508A (da)
EP (1)	EP0826657B1 (da)
JP (1)	JP2910995B2 (da)
AT (1)	ATE203743T1 (da)
AU (1)	AU703076B2 (da)
CA (1)	CA2213609C (da)
DE (1)	DE69705902T2 (da)
DK (1)	DK0826657T3 (da)
ES (1)	ES2163723T3 (da)
FR (1)	FR2752837B1 (da)
GR (1)	GR3036997T3 (da)
PT (1)	PT826657E (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7655699B1 (en)	1992-04-22	2010-02-02	Eisai Inc.	Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US6566372B1 (en)	1999-08-27	2003-05-20	Ligand Pharmaceuticals Incorporated	Bicyclic androgen and progesterone receptor modulator compounds and methods
KR20020038741A (ko)	1999-08-27	2002-05-23	윌리암 엘. 레스페스	안드로겐 수용체 조절 화합물 및 방법
JP2003508397A (ja)	1999-08-27	2003-03-04	リガンド・ファーマシューティカルズ・インコーポレイテッド	アンドロゲンレセプターモジュレーターとしての８−置換−６−トリフルオロメチル−９−ピリド［３，２−ｇ］キノリン化合物
AU7586600A (en) *	1999-09-14	2001-04-17	Ligand Pharmaceuticals Incorporated	Rxr modulators with improved pharmacologic profile
US7314953B2 (en) *	2001-03-27	2008-01-01	Errant Gene Therapeutics, Llc	Treatment of lung cells with histone deacetylase inhibitors
US7312247B2 (en)	2001-03-27	2007-12-25	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors
US6495719B2 (en)	2001-03-27	2002-12-17	Circagen Pharmaceutical	Histone deacetylase inhibitors
US8026280B2 (en)	2001-03-27	2011-09-27	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors
US7842727B2 (en) *	2001-03-27	2010-11-30	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors
EP1511477A4 (en) *	2002-05-22	2008-04-09	Errant Gene Therapeutics Llc	HISTONE DEACETYLASE INHIBITORS BASED ON ALPHA-KETO-EPOXYDE COMPOUNDS
US20060160902A1 (en) *	2004-11-08	2006-07-20	Wiech Norbert L	Histone deacetylase inhibitors
FR2910321B1 (fr)	2006-12-21	2009-07-10	Galderma Res & Dev S N C Snc	Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr)	2006-12-21	2009-02-13	Galderma Res & Dev S N C Snc	Emulsion comprenant au moins un retinoide et du peroxyde de benzole
FR2931661B1 (fr)	2008-05-30	2010-07-30	Galderma Res & Dev	Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide.
US9128079B2 (en)	2011-08-08	2015-09-08	The Coca-Cola Company	Methods of using lung or bronchial epithelial cells to identify bitter taste modulators
KR102170307B1 (ko) *	2012-11-15	2020-10-26	주식회사 알엔에스	탈모방지 및 모발성장 촉진제 조성물
AU2018367653B2 (en) *	2017-11-17	2020-11-12	Io Therapeutics, Inc.	Compounds and synthetic methods for the preparation of retinoid X receptor-specific retinoids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LU77254A1 (da) *	1977-05-04	1979-01-18
AU626881B2 (en) *	1988-07-14	1992-08-13	F. Hoffmann-La Roche Ag	Benzofused heterocyclics used as pharmaceuticals
ATE195716T1 (de) *	1992-04-22	2000-09-15	Ligand Pharm Inc	Retinoid-x rezeptor selektive verbindungen
CA2093577C (en) *	1992-05-07	2006-01-03	Michael Klaus	Alkyl or alkoxy substituted s-heterocyclic retinoids
ES2129115T3 (es) *	1993-01-11	1999-06-01	Ligand Pharm Inc	Compuestos que tienen actividad selectiva para los receptores de retinoides x, y medios para la modulacion de procesos mediados por receptores de retinoides x.

1996
- 1996-09-02 FR FR9610686A patent/FR2752837B1/fr not_active Expired - Fee Related
1997
- 1997-08-27 DE DE69705902T patent/DE69705902T2/de not_active Expired - Fee Related
- 1997-08-27 AT AT97401999T patent/ATE203743T1/de not_active IP Right Cessation
- 1997-08-27 DK DK97401999T patent/DK0826657T3/da active
- 1997-08-27 PT PT97401999T patent/PT826657E/pt unknown
- 1997-08-27 EP EP97401999A patent/EP0826657B1/fr not_active Expired - Lifetime
- 1997-08-27 ES ES97401999T patent/ES2163723T3/es not_active Expired - Lifetime
- 1997-08-28 AU AU36059/97A patent/AU703076B2/en not_active Ceased
- 1997-08-29 CA CA002213609A patent/CA2213609C/fr not_active Expired - Fee Related
- 1997-09-01 JP JP9236309A patent/JP2910995B2/ja not_active Expired - Fee Related
- 1997-09-02 US US08/921,591 patent/US5910508A/en not_active Expired - Fee Related
2001
- 2001-10-24 GR GR20010401870T patent/GR3036997T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU3605997A (en)	1998-03-05
FR2752837B1 (fr)	1999-11-12
DE69705902T2 (de)	2001-11-15
US5910508A (en)	1999-06-08
CA2213609C (fr)	2002-06-25
EP0826657A1 (fr)	1998-03-04
JP2910995B2 (ja)	1999-06-23
PT826657E (pt)	2001-12-28
CA2213609A1 (fr)	1998-03-02
JPH10101641A (ja)	1998-04-21
DE69705902D1 (de)	2001-09-06
GR3036997T3 (en)	2002-01-31
EP0826657B1 (fr)	2001-08-01
AU703076B2 (en)	1999-03-11
ATE203743T1 (de)	2001-08-15
ES2163723T3 (es)	2002-02-01
FR2752837A1 (fr)	1998-03-06

Publication	Publication Date	Title
DK0826657T3 (da)	2001-10-22	Hidtil ukendte forbindelser til modulering af hormonreceptorer, sammensætninger, der omfatter dem, og deres anvendelse i terapi
ES8501384A1 (es)	1984-11-16	Procedimiento para preparar derivados de piperazina
DE69523169D1 (de)	2001-11-15	Verwendung von Mangiferin oder seinen Derivaten zur kosmetischen Anwendung
AU2664197A (en)	1997-11-07	Thieno-pyridine sulfonamides, derivatives thereof and related compounds that modulate the activity of endothelin
BG103964A (en)	2000-08-31	SUBSTITUTED PYRAZOLS AS p38 KINASE INHIBITORS
YU64092A (sh)	1995-03-27	Fluoralkoksibenzamino derivati heterocikličnih jedinjenja koja sadrže azot
NZ331319A (en)	2000-03-27	Cyclic amine derivatives that are CCR-3 receptor (chemokine receptor) antagonists, compositions containing them and methods for their use (to combat eosinophil induced diseases).
TW200507839A (en)	2005-03-01	Therapeutic agents
NZ332658A (en)	2000-05-26	Halo-substituted bis-indolylmaleimide derivatives and pharmaceutical compositions
MY101614A (en)	1991-12-17	Improvements in or relating to benzothiophene derivatives as antiasthmatic agents
PL313822A1 (en)	1996-07-22	Derivatives of antracycline and their application in treating amyloidoses
NO954576L (no)	1996-01-15	AMPA antagonister og en fremgangsmåte til behandling med dem
BG102015A (en)	1998-08-31	Azacycloalkane derivatives, their preparation and application in therapy
ES2012648A6 (es)	1990-04-01	Procedimiento para la preparacion de nuevos derivados de 1,4-benzoxazina y 1,4-benzotiazina.
CO4960660A1 (es)	2000-09-25	Derivados de 5-aroil-pirrol-2-ilmetilareno, composiciones farmaceuticas que las contienen y metodos para la preparacion de estos compuestos
TW347311B (en)	1998-12-11	Fungicidal mixtures
NO910167D0 (no)	1991-01-15	Haarfargemiddel.
NZ512934A (en)	2003-06-30	Synergistic fungicidal mixture of a 4-phenoxy-quinoline derivative and a 1,2-diazole carbamate derivative or 1,2,4-triazole carbamate derivative
BR9609991A (pt)	1999-07-06	Carbamoilcarboxamida composição adequada para controlar fungos nocivos processos para a preparação de uma carbamoilcarboxamida para preparação da composição e para controle de fungos nocivos e uso de um composto ou de uma composição
NZ505547A (en)	2003-03-28	Synergistic fungicide mixtures based on amide compounds and pyridine or oxime derivatives
DE69521895D1 (de)	2001-08-30	Indolderivate als prodrugs von "5-ht1-like" rezeptor agonisten
DE68910090D1 (de)	1993-11-25	Verwendung heterozyklischer Amide zur Verhinderung der Tumormetastasierung.
DE3770481D1 (de)	1991-07-11	Verwendung von imidazochinazolinen zur behandlung und verhinderung von nephritis.
IL66239A0 (en)	1982-11-30	Synergistic compositions and method for selectively combating weeds,especially in cereal crops
MX9603868A (es)	1997-03-29	Composicion farmaceutica de derivados de indeno para la regulacion de la apoptosis.