DK0834314T3 - Granuler der indeholder pranlukast, fremgangsmåde til fremstilling af granulerne, og fremgangsmåde til reduktion af pranlukasts klæbeevne - Google Patents
Granuler der indeholder pranlukast, fremgangsmåde til fremstilling af granulerne, og fremgangsmåde til reduktion af pranlukasts klæbeevneInfo
- Publication number
- DK0834314T3 DK0834314T3 DK96916361T DK96916361T DK0834314T3 DK 0834314 T3 DK0834314 T3 DK 0834314T3 DK 96916361 T DK96916361 T DK 96916361T DK 96916361 T DK96916361 T DK 96916361T DK 0834314 T3 DK0834314 T3 DK 0834314T3
- Authority
- DK
- Denmark
- Prior art keywords
- pranlukast
- granules
- adhesiveness
- containing granules
- reducing
- Prior art date
Links
- UAJUXJSXCLUTNU-UHFFFAOYSA-N pranlukast Chemical compound C=1C=C(OCCCCC=2C=CC=CC=2)C=CC=1C(=O)NC(C=1)=CC=C(C(C=2)=O)C=1OC=2C=1N=NNN=1 UAJUXJSXCLUTNU-UHFFFAOYSA-N 0.000 title abstract 8
- 229960004583 pranlukast Drugs 0.000 title abstract 8
- 239000008187 granular material Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 238000010924 continuous production Methods 0.000 abstract 1
- 238000009826 distribution Methods 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16929295 | 1995-06-12 | ||
| PCT/JP1996/001578 WO1996041628A1 (en) | 1995-06-12 | 1996-06-11 | Granules containing pranlukast, process for producing the granules, and method of lowering cohesiveness of pranlukast |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0834314T3 true DK0834314T3 (da) | 2003-02-24 |
Family
ID=15883819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96916361T DK0834314T3 (da) | 1995-06-12 | 1996-06-11 | Granuler der indeholder pranlukast, fremgangsmåde til fremstilling af granulerne, og fremgangsmåde til reduktion af pranlukasts klæbeevne |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5876760A (da) |
| EP (1) | EP0834314B1 (da) |
| KR (1) | KR100389606B1 (da) |
| AT (1) | ATE230987T1 (da) |
| DE (1) | DE69625813T2 (da) |
| DK (1) | DK0834314T3 (da) |
| ES (1) | ES2191101T3 (da) |
| WO (1) | WO1996041628A1 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19617487A1 (de) † | 1996-05-02 | 1997-11-06 | Merck Patent Gmbh | Geschmacksverbesserung von Arzneimittelwirkstoffen |
| TW546151B (en) | 1997-07-23 | 2003-08-11 | Senju Pharma Co | Aqueous liquid pharmaceutical composition containing as main component benzopyran derivative |
| ID27887A (id) * | 1998-04-18 | 2001-05-03 | Glaxo Group Ltd | Formulasi aerosol farmasi |
| DE19945982A1 (de) | 1999-09-24 | 2001-03-29 | Knoll Ag | Geschwindigkeitsbestimmte Partikel |
| KR100381834B1 (ko) * | 2000-05-20 | 2003-04-26 | 이상득 | 용출성이 개선된 프란루카스트 고체분산체 조성물 및 그제조 방법 |
| US6692976B1 (en) * | 2000-08-31 | 2004-02-17 | Agilent Technologies, Inc. | Post-etch cleaning treatment |
| CN101022796B (zh) | 2004-07-14 | 2013-02-27 | 炎症研究中心有限公司 | 抑制肿瘤转移的方法 |
| KR100591786B1 (ko) | 2004-10-19 | 2006-06-26 | 휴먼팜 주식회사 | 프란루카스트를 함유하는 약학적 조성물 및 이의 제조 방법 |
| KR101086254B1 (ko) * | 2004-11-04 | 2011-11-24 | 에스케이케미칼주식회사 | 생체이용률이 개선된 프란루카스트 고체분산체 조성물 및그 고체분산체의 제조방법 |
| WO2006109737A1 (ja) * | 2005-04-11 | 2006-10-19 | Ono Pharmaceutical Co., Ltd. | 苦味が低減されたプランルカスト水和物を含有する製剤 |
| DE102005026755A1 (de) * | 2005-06-09 | 2006-12-14 | Basf Ag | Herstellung von festen Lösungen schwerlöslicher Wirkstoffe durch Kurzzeitüberhitzung und schnelle Trocknung |
| KR101233235B1 (ko) * | 2005-08-26 | 2013-02-15 | 에스케이케미칼주식회사 | 초기 용출율이 개선된 프란루카스트 고체분산체의 약제학적조성물 및 그의 제조방법 |
| KR100715355B1 (ko) | 2005-09-30 | 2007-05-07 | 주식회사유한양행 | 프란루카스트를 함유하는 분무-건조 과립 및 그의 제조방법 |
| KR100981751B1 (ko) * | 2005-10-28 | 2010-09-10 | 주식회사유한양행 | 프란루카스트를 함유하는 과립 및 그의 제조방법 |
| KR100981750B1 (ko) * | 2005-10-28 | 2010-09-10 | 주식회사유한양행 | 분무-건조 과립 및 그의 제조방법 |
| ZA200905094B (en) * | 2006-12-22 | 2010-09-29 | Yuhan Corp | Revaprazan-containing solid dispersion and process for the preparation thereof |
| KR102363727B1 (ko) | 2015-06-01 | 2022-02-16 | 삼아제약 주식회사 | 생체이용률이 개선된 프란루카스트 함유 고형 제제의 조성물 및 그 제조방법 |
| CN116270902B (zh) * | 2023-04-26 | 2024-08-20 | 南京同仁堂药业有限责任公司 | 一种颈舒颗粒及其制备方法 |
| KR20240164596A (ko) | 2023-05-09 | 2024-11-20 | 삼아제약 주식회사 | 복약편의성이 증진된 프란루카스트 함유 약제학적 조성물 |
| KR102840220B1 (ko) | 2023-07-18 | 2025-07-31 | 삼아제약 주식회사 | 프란루카스트 함유 약제학적 조성물의 제조방법 및 상기 제조방법에 의해 제조된 약제학적 조성물 |
| KR20250052834A (ko) | 2023-10-12 | 2025-04-21 | 주식회사 다산제약 | 프란루카스트의 생체이용률이 개선된 약제학적 조성물 및 그 제조방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994458A (en) * | 1990-04-30 | 1991-02-19 | Basf Corporation | Process for rotary fluid bed granulation of riboflavin |
| CA2131787A1 (en) * | 1992-03-12 | 1993-09-16 | Masahiko Shikano | Antipruritic |
| JPH0776516A (ja) * | 1993-09-06 | 1995-03-20 | Toyobo Co Ltd | 難溶性薬物含有製剤の製造方法 |
-
1996
- 1996-06-11 ES ES96916361T patent/ES2191101T3/es not_active Expired - Lifetime
- 1996-06-11 WO PCT/JP1996/001578 patent/WO1996041628A1/ja not_active Ceased
- 1996-06-11 DE DE69625813T patent/DE69625813T2/de not_active Expired - Fee Related
- 1996-06-11 AT AT96916361T patent/ATE230987T1/de not_active IP Right Cessation
- 1996-06-11 DK DK96916361T patent/DK0834314T3/da active
- 1996-06-11 US US08/981,083 patent/US5876760A/en not_active Expired - Fee Related
- 1996-06-11 KR KR1019970709260A patent/KR100389606B1/ko not_active Expired - Lifetime
- 1996-06-11 EP EP96916361A patent/EP0834314B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990022791A (ko) | 1999-03-25 |
| US5876760A (en) | 1999-03-02 |
| ES2191101T3 (es) | 2003-09-01 |
| EP0834314B1 (en) | 2003-01-15 |
| WO1996041628A1 (en) | 1996-12-27 |
| EP0834314A4 (en) | 2000-05-10 |
| ATE230987T1 (de) | 2003-02-15 |
| EP0834314A1 (en) | 1998-04-08 |
| DE69625813D1 (de) | 2003-02-20 |
| DE69625813T2 (de) | 2003-09-04 |
| KR100389606B1 (ko) | 2003-09-26 |
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