DK0836473T3 - Ringformede indretninger - Google Patents

Ringformede indretninger

Info

Publication number: DK0836473T3
Authority: DK; Denmark
Prior art keywords: compartment; ethylene; vinylacetate copolymer; vinylacetate; medicated
Prior art date: 1995-07-04

Application number

DK96922907T

Other languages

Danish (da)

English (en)

Inventor

Rudolf Johannes Jo Groenewegen

Antonius Paulus Sam

Herman Vromans

Hendrik De Nijs

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-04

Filing date

1996-07-01

Publication date

2002-02-11

1996-07-01 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2002-02-11 Application granted granted Critical

2002-02-11 Publication of DK0836473T3 publication Critical patent/DK0836473T3/da

Links

239000005038 ethylene vinyl acetate Substances 0.000 abstract 4
229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 abstract 4
229940068196 placebo Drugs 0.000 abstract 2
239000000902 placebo Substances 0.000 abstract 2
239000003270 steroid hormone Substances 0.000 abstract 2
MXDOOIVQXATHKU-RYVPXURESA-N (8s,9s,10r,13s,14s,17r)-13-ethyl-17-ethynyl-17-hydroxy-11-methylidene-2,6,7,8,9,10,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-3-one;(8r,9s,13s,14s,17r)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthrene-3,17-diol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1.O=C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 MXDOOIVQXATHKU-RYVPXURESA-N 0.000 abstract 1
DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 abstract 1
229920001577 copolymer Polymers 0.000 abstract 1
125000000816 ethylene group Chemical class [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
GCKFUYQCUCGESZ-BPIQYHPVSA-N etonogestrel Chemical compound O=C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 GCKFUYQCUCGESZ-BPIQYHPVSA-N 0.000 abstract 1
229960002941 etonogestrel Drugs 0.000 abstract 1
229920001903 high density polyethylene Polymers 0.000 abstract 1
239000004700 high-density polyethylene Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229920000642 polymer Polymers 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
239000012815 thermoplastic material Substances 0.000 abstract 1
229940044953 vaginal ring Drugs 0.000 abstract 1
239000006213 vaginal ring Substances 0.000 abstract 1
229940117958 vinyl acetate Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms

Landscapes

Health & Medical Sciences (AREA)
Reproductive Health (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Gynecology & Obstetrics (AREA)
Urology & Nephrology (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Containers And Plastic Fillers For Packaging (AREA)
Iron Core Of Rotating Electric Machines (AREA)
Finger-Pressure Massage (AREA)
Packaging Of Special Articles (AREA)
Magnetic Resonance Imaging Apparatus (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK96922907T 1995-07-04 1996-07-01 Ringformede indretninger DK0836473T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95201818		1995-07-04
PCT/EP1996/002935 WO1997002015A1 (en)	1995-07-04	1996-07-01	Ring-shaped devices

Publications (1)

Publication Number	Publication Date
DK0836473T3 true DK0836473T3 (da)	2002-02-11

Family

ID=8220451

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96922907T DK0836473T3 (da)	1995-07-04	1996-07-01	Ringformede indretninger

Country Status (8)

Country	Link
US (2)	US6544546B1 (de)
EP (1)	EP0836473B1 (de)
AT (1)	ATE207736T1 (de)
AU (1)	AU6360896A (de)
DE (1)	DE69616551T2 (de)
DK (1)	DK0836473T3 (de)
ES (1)	ES2166894T3 (de)
WO (1)	WO1997002015A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL123813A0 (en) *	1997-04-11	1998-10-30	Akzo Nobel Nv	Drug delivery system for two or more active substances
US7357046B2 (en)	2002-12-16	2008-04-15	N. V. Organon	Method for dissolution testing of a pharmaceutical delivery device
AU2004233997C1 (en) *	2003-04-29	2014-01-30	Massachusetts Institiute Of Technology	Methods and devices for the sustained release of multiple drugs
TWI336627B (en)	2003-05-23	2011-02-01	Organon Nv	Drug delivery system,and use and manufacturing method thereof
CN100531800C (zh) *	2004-03-24	2009-08-26	奥尔加侬股份有限公司	基于聚乙烯乙酸乙烯酯共聚物的药物递送系统
CN100366242C (zh) *	2005-01-13	2008-02-06	杭州容立医药科技有限公司	防滑脱阴道药物释放体系及其制造工艺和在制药中的应用
EP1853272A1 (de) *	2005-02-03	2007-11-14	Duramed Pharmaceuticals, Inc.	Zusammensetzungen aus unkonjugierten östrogenen und anwendungsverfahren dafür
US8399012B2 (en)	2006-04-17	2013-03-19	Kimberly-Clark Worldwide, Inc.	Degradable therapeutic delivery device
US20070254025A1 (en) *	2006-04-27	2007-11-01	Cronk Peter J	Oral contraceptive and acne medication combination and treatment of acne with reduced side effects
US20070254858A1 (en) *	2006-04-27	2007-11-01	Cronk Peter J	Contraceptive and Acne Medication Combination and Treatment of Acne and Other Diseases with Reduced Side Effects
MX2009005444A (es) *	2006-11-22	2009-06-02	Organon Nv	Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado.
US8741329B2 (en) *	2007-09-21	2014-06-03	Merck Sharp & Dohme B.V.	Drug delivery system
PL2062569T3 (pl) *	2007-11-22	2011-10-31	Bayer Oy	Dopochwowy układ dostarczania leku
EP2062568A1 (de) *	2007-11-22	2009-05-27	Bayer Schering Pharma Oy	System zur vaginalen Freisetzung
TW200927141A (en) *	2007-11-22	2009-07-01	Bayer Schering Pharma Oy	Vaginal delivery system
EP2359807B1 (de)	2008-02-04	2017-07-26	Ferring B.V.	Monolithische intravaginale ringe mit progesteron und verfahren zu ihrer herstellung und verwendung
US20100040671A1 (en) *	2008-08-12	2010-02-18	Ahmed Salah U	Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
EP2437684B1 (de)	2009-06-03	2022-06-15	ForSight Vision5, Inc.	Wirkstofffreisetzung im vorderen augensegment
BR112012001353B8 (pt)	2009-07-21	2021-05-25	The Population Council Inc	anel vaginal, e, método para fabricar um anel vaginal
KR101914119B1 (ko)	2010-03-16	2018-11-02	타이탄 파머슈티컬즈 인코퍼레이티드	약물 전달용 이종 이식가능 장치
EP2749286B1 (de) *	2011-08-26	2017-03-01	Universidad De Santiago De Chile	Verwendung der nichtsteroidalen entzündungshemmer meloxicam und piroxicam in intravaginalringen zur unterbrechung des eisprungs bei frauen
GB201115592D0 (en) *	2011-09-09	2011-10-26	Vivosens Medical Gmbh	Flexible ring pessary
TR201808748T4 (tr)	2012-09-03	2018-07-23	Ecosea Farming S A	Hidrobiyolojik türlerin kültürü ve/veya korunmasına yönelik rezervuar-kafes daldırma sistemi.
US10596103B2 (en)	2013-12-11	2020-03-24	Merek Sharp & Dohme B.V.	Drug delivery system for delivery of anti-virals
US10413504B2 (en)	2013-12-11	2019-09-17	Merck Sharp & Dohme Corp.	Intravaginal ring drug delivery system
WO2016156403A1 (en) *	2015-03-31	2016-10-06	Merck Sharp & Dohme B.V.	Vaginal ring applicator
US20160296532A1 (en)	2015-04-13	2016-10-13	Forsight Vision5, Inc.	Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
CN108135910B (zh)	2015-05-13	2022-12-02	拜耳股份有限公司	长效药物递送装置及其在避孕中的用途
EP3395335A1 (de)	2017-04-24	2018-10-31	Kern Pharma, S.L.	Vaginalring zur gleichzeitigen freisetzung zweier wirkstoffe
US11689849B2 (en)	2018-05-24	2023-06-27	Nureva, Inc.	Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones
KR20260007295A (ko)	2018-05-24	2026-01-13	셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨	거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치
US11690806B2 (en)	2018-05-24	2023-07-04	Celanese Eva Performance Polymers Llc	Implantable device for sustained release of a macromolecular drug compound
CN113365634A (zh) *	2018-12-11	2021-09-07	卢品公司	超低剂量雌激素组合的药物递送系统及其方法和用途
KR102159904B1 (ko)	2020-04-24	2020-09-24	강경원	약물 방출 고리를 구비한 월경컵
BR112023022439A2 (pt)	2021-04-26	2023-12-26	Celanese Eva Performance Polymers Llc	Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular
CA3251695A1 (en) *	2022-02-22	2023-08-31	Celanese Eva Performance Polymers Llc	Intravaginal ring device for the administration of an aromatase inhibitor
EP4507675A1 (de) *	2022-04-14	2025-02-19	Yale University	Nanopartikel und nanopartikelfreisetzende vaginalringe
CA3259928A1 (en) *	2022-08-01	2024-02-08	Lupin Inc.	DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4188951A (en) *	1972-08-17	1980-02-19	Alza Corporation	Intrauterine system embracing selected copolymeric membranes for administering beneficial agent
DE2616064A1 (de) *	1976-04-09	1977-10-20	Schering Ag	Vaginalring iii
US4237885A (en)	1978-10-23	1980-12-09	Alza Corporation	Delivery system with mated members for storing and releasing a plurality of beneficial agents
US4292965A (en) *	1978-12-29	1981-10-06	The Population Council, Inc.	Intravaginal ring
DE3040978A1 (de)	1980-10-28	1982-05-27	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Vaginalring
US4596576A (en) *	1984-10-12	1986-06-24	Akzo N.V.	Release system for two or more active substances

1996
- 1996-07-01 WO PCT/EP1996/002935 patent/WO1997002015A1/en not_active Ceased
- 1996-07-01 ES ES96922907T patent/ES2166894T3/es not_active Expired - Lifetime
- 1996-07-01 US US08/981,881 patent/US6544546B1/en not_active Expired - Fee Related
- 1996-07-01 EP EP96922907A patent/EP0836473B1/de not_active Expired - Lifetime
- 1996-07-01 DE DE69616551T patent/DE69616551T2/de not_active Expired - Fee Related
- 1996-07-01 AT AT96922907T patent/ATE207736T1/de not_active IP Right Cessation
- 1996-07-01 AU AU63608/96A patent/AU6360896A/en not_active Abandoned
- 1996-07-01 DK DK96922907T patent/DK0836473T3/da active
2003
- 2003-02-25 US US10/374,183 patent/US20030152625A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE69616551D1 (de)	2001-12-06
EP0836473B1 (de)	2001-10-31
DE69616551T2 (de)	2002-05-29
AU6360896A (en)	1997-02-05
ATE207736T1 (de)	2001-11-15
US6544546B1 (en)	2003-04-08
WO1997002015A1 (en)	1997-01-23
EP0836473A1 (de)	1998-04-22
US20030152625A1 (en)	2003-08-14
ES2166894T3 (es)	2002-05-01

Publication	Publication Date	Title
DK0836473T3 (da)	2002-02-11	Ringformede indretninger
AR011709A1 (es)	2000-08-30	Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal
KR100312764B1 (ko)	2002-11-23	질내전달시스템
AU620940B2 (en)	1992-02-27	Contraception system and method
EP0279977A2 (de)	1988-08-31	Transdermale Verabreichung von Progesteron, Östradiolestern und deren Mischungen
CA2188907A1 (en)	1997-04-29	Combination compound for contraception based on natural estrogen
IE42345L (en)	1976-04-18	Vaginal ring
WO1995011013A3 (de)	1995-06-29	Kombination von progesteronantagonisten und antiöstrogenen mit partialer agonistischer wirkung für die hormonsubstitutions-therapie für peri- und postmenopausale frauen
WO1997049394A3 (en)	2001-12-20	Sold oral dosage forms of valsartan
CA2221096A1 (en)	1996-12-19	Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate
JPS6470410A (en)	1989-03-15	Contraceptive implant
GR3003031T3 (en)	1993-02-17	Granule remaining in stomach
LU90343I2 (fr)	1999-03-29	Combinaison d'oestradiol (sous forme d'hémihydrate) ph. eur 1mg et d'acétate de norethistérone (sous forme d'hémihydrate) ph. eur 0,5 m (activelle)
BG101553A (en)	1998-09-30	Progesterone antagonist and antiestrogenous active compounds of general application for female contraceptives
AU2016992A (en)	1992-12-30	Multi-layered controlled release formulation
IE43546L (en)	1977-03-12	Container
RU96119803A (ru)	1998-12-20	Комбинированный препарат для контрацепции на базе природных эстрогенов
ATE290836T1 (de)	2005-04-15	Intravaginal-ringe mit einsetzbarem medikamentenenthaltenden kern
DK1011682T3 (da)	2003-09-22	Hormonalt antikonceptionsmiddel
CA2708347A1 (en)	2005-03-03	Transdermal patch incorporating active agent migration barrier layer
DE3069013D1 (en)	1984-09-27	Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone, their preparation and pharmaceutical compositions containing them
WO1999020223A3 (en)	1999-07-01	Luteinising hormone antagonists useful for treatment of estrogen deficiencies, or as a contraceptive
De Leede et al.	1986	A multi-compartment vaginal ring system for independently adjustable release of contraceptive steroids
RU2002113654A (ru)	2004-01-27	Противозачаточное лекарственное средство на основе гестагена и эстрогена и способ его получения
AU1092095A (en)	1995-01-17	Intra-uterine ring for the release of an active agent, such as a hormone, and an introducer