DK0839149T3 - Galanthamin-derivater, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemidler og farmaceutiske præparater omfattende dem - Google Patents

Galanthamin-derivater, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemidler og farmaceutiske præparater omfattende dem

Info

Publication number
DK0839149T3
DK0839149T3 DK96926431T DK96926431T DK0839149T3 DK 0839149 T3 DK0839149 T3 DK 0839149T3 DK 96926431 T DK96926431 T DK 96926431T DK 96926431 T DK96926431 T DK 96926431T DK 0839149 T3 DK0839149 T3 DK 0839149T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical compositions
pct
pharmaceuticals
preparation
derivatives
Prior art date
Application number
DK96926431T
Other languages
English (en)
Inventor
Pierre Potier
Claude Thal
Catherine Guillou
Aude Mary
Dolor Renko
Yves Christen
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of DK0839149T3 publication Critical patent/DK0839149T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK96926431T 1995-07-19 1996-07-19 Galanthamin-derivater, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemidler og farmaceutiske præparater omfattende dem DK0839149T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514821.9A GB9514821D0 (en) 1995-07-19 1995-07-19 Galanthamine derivatives
PCT/FR1996/001139 WO1997003987A1 (fr) 1995-07-19 1996-07-19 Nouveaux derives de la galanthamine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
DK0839149T3 true DK0839149T3 (da) 2004-08-09

Family

ID=10777948

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96926431T DK0839149T3 (da) 1995-07-19 1996-07-19 Galanthamin-derivater, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemidler og farmaceutiske præparater omfattende dem

Country Status (16)

Country Link
US (1) US5958903A (da)
EP (1) EP0839149B9 (da)
JP (1) JP4177894B2 (da)
AT (1) ATE264332T1 (da)
AU (1) AU6662396A (da)
CA (1) CA2227235C (da)
DE (1) DE69632194T2 (da)
DK (1) DK0839149T3 (da)
ES (1) ES2218596T3 (da)
GB (1) GB9514821D0 (da)
IL (1) IL122739A0 (da)
MX (1) MX9800407A (da)
NO (1) NO980215L (da)
PT (1) PT839149E (da)
WO (1) WO1997003987A1 (da)
ZA (1) ZA966163B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1604653A1 (en) * 1998-09-30 2005-12-14 Takeda Pharmaceutical Company Limited Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder
AU1738800A (en) 1998-11-23 2000-06-13 Bonnie Davis Dosage formulations for acetylcholinesterase inhibitors
KR100437105B1 (ko) 1998-12-24 2004-06-23 얀센 파마슈티카 엔.브이. 방출 조절형 갈란타민 조성물
US8603546B2 (en) * 1999-01-11 2013-12-10 Herbaceuticals Inc. Herbal supplement for increased muscle strength and endurance for athletes
WO2000041540A2 (en) * 1999-01-11 2000-07-20 Atanas Russinov Djananov Herbal supplement for increased muscle strength and endurance for athletes
ES2211056T3 (es) * 1999-03-31 2004-07-01 Eisai Co., Ltd. Composiciones estabilizadas que contienen farmacos nootropicos.
PL202463B1 (pl) * 2000-03-31 2009-06-30 Sanochemia Pharmazeutika Ag Pochodne galantaminy, sposób ich wytwarzania, środek leczniczy zawierajacy te pochodne, zastosowanie pochodnej galantaminy do wytwarzania środków leczniczych, sposób wytwarzania środków leczniczych oraz sposób oddzielania (+)- i (-)-izomerów
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
DE10134038A1 (de) * 2001-07-12 2003-02-06 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit
CN1646536A (zh) * 2002-03-25 2005-07-27 萨诺化学萨物股份公司 制备降雪花胺以及其异构体、盐和水合物的方法
CA2506282A1 (en) * 2003-09-29 2005-04-07 Sanochemia Pharmazeutika Ag Use of galanthamine and the derivatives thereof in the production of medicaments
AT414125B (de) * 2003-09-29 2006-09-15 Sanochemia Pharmazeutika Ag Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln
WO2005065661A2 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galanthamine
WO2005065662A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
WO2006124584A2 (en) * 2005-05-13 2006-11-23 Alza Corporation Multilayer drug delivery system with barrier against reservoir material flow
WO2007035941A2 (en) * 2005-09-23 2007-03-29 Alza Corporation Transdermal galantamine delivery system
WO2010029554A1 (en) 2008-09-11 2010-03-18 I.B.R. Israeli Biotechnology Research Ltd. Leucojum bulb extracts and use thereof
US20120129838A1 (en) * 2009-04-24 2012-05-24 The Industry & Academic Cooperation In Chungnam National University Composition for Preventing and Treating Alopecia Disorder Containing Morgalanthamine Compounds as an Active Ingredient

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663318A (en) * 1986-01-15 1987-05-05 Bonnie Davis Method of treating Alzheimer's disease
US4735169A (en) * 1986-09-03 1988-04-05 Nordson Corporation Adhesive applicator assembly
JP2755403B2 (ja) * 1987-05-04 1998-05-20 デイービス、ボニー アルツハイマー病の治療のための化合物
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
US6323195B1 (en) * 1993-10-15 2001-11-27 Aventis Pharmaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
US5428159A (en) * 1994-04-08 1995-06-27 Ciba-Geigy Corporation Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine

Also Published As

Publication number Publication date
DE69632194D1 (de) 2004-05-19
EP0839149B9 (fr) 2005-03-09
AU6662396A (en) 1997-02-18
NO980215D0 (no) 1998-01-16
MX9800407A (es) 1998-04-30
GB9514821D0 (en) 1995-09-20
ZA966163B (en) 1997-02-10
CA2227235A1 (fr) 1997-02-06
PT839149E (pt) 2004-08-31
JPH11509541A (ja) 1999-08-24
IL122739A0 (en) 1998-08-16
ES2218596T3 (es) 2004-11-16
ATE264332T1 (de) 2004-04-15
CA2227235C (fr) 2010-08-31
EP0839149B1 (fr) 2004-04-14
NO980215L (no) 1998-01-16
WO1997003987A1 (fr) 1997-02-06
US5958903A (en) 1999-09-28
DE69632194T2 (de) 2005-03-17
JP4177894B2 (ja) 2008-11-05
EP0839149A1 (fr) 1998-05-06

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