DK0839149T3 - Galanthamin-derivater, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemidler og farmaceutiske præparater omfattende dem - Google Patents
Galanthamin-derivater, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemidler og farmaceutiske præparater omfattende demInfo
- Publication number
- DK0839149T3 DK0839149T3 DK96926431T DK96926431T DK0839149T3 DK 0839149 T3 DK0839149 T3 DK 0839149T3 DK 96926431 T DK96926431 T DK 96926431T DK 96926431 T DK96926431 T DK 96926431T DK 0839149 T3 DK0839149 T3 DK 0839149T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical compositions
- pct
- pharmaceuticals
- preparation
- derivatives
- Prior art date
Links
- ASUTZQLVASHGKV-JDFRZJQESA-N galanthamine Chemical class O1C(=C23)C(OC)=CC=C2CN(C)CC[C@]23[C@@H]1C[C@@H](O)C=C2 ASUTZQLVASHGKV-JDFRZJQESA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 239000000544 cholinesterase inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9514821.9A GB9514821D0 (en) | 1995-07-19 | 1995-07-19 | Galanthamine derivatives |
| PCT/FR1996/001139 WO1997003987A1 (fr) | 1995-07-19 | 1996-07-19 | Nouveaux derives de la galanthamine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0839149T3 true DK0839149T3 (da) | 2004-08-09 |
Family
ID=10777948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96926431T DK0839149T3 (da) | 1995-07-19 | 1996-07-19 | Galanthamin-derivater, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemidler og farmaceutiske præparater omfattende dem |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5958903A (da) |
| EP (1) | EP0839149B9 (da) |
| JP (1) | JP4177894B2 (da) |
| AT (1) | ATE264332T1 (da) |
| AU (1) | AU6662396A (da) |
| CA (1) | CA2227235C (da) |
| DE (1) | DE69632194T2 (da) |
| DK (1) | DK0839149T3 (da) |
| ES (1) | ES2218596T3 (da) |
| GB (1) | GB9514821D0 (da) |
| IL (1) | IL122739A0 (da) |
| MX (1) | MX9800407A (da) |
| NO (1) | NO980215L (da) |
| PT (1) | PT839149E (da) |
| WO (1) | WO1997003987A1 (da) |
| ZA (1) | ZA966163B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1604653A1 (en) * | 1998-09-30 | 2005-12-14 | Takeda Pharmaceutical Company Limited | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder |
| AU1738800A (en) | 1998-11-23 | 2000-06-13 | Bonnie Davis | Dosage formulations for acetylcholinesterase inhibitors |
| KR100437105B1 (ko) | 1998-12-24 | 2004-06-23 | 얀센 파마슈티카 엔.브이. | 방출 조절형 갈란타민 조성물 |
| US8603546B2 (en) * | 1999-01-11 | 2013-12-10 | Herbaceuticals Inc. | Herbal supplement for increased muscle strength and endurance for athletes |
| WO2000041540A2 (en) * | 1999-01-11 | 2000-07-20 | Atanas Russinov Djananov | Herbal supplement for increased muscle strength and endurance for athletes |
| ES2211056T3 (es) * | 1999-03-31 | 2004-07-01 | Eisai Co., Ltd. | Composiciones estabilizadas que contienen farmacos nootropicos. |
| PL202463B1 (pl) * | 2000-03-31 | 2009-06-30 | Sanochemia Pharmazeutika Ag | Pochodne galantaminy, sposób ich wytwarzania, środek leczniczy zawierajacy te pochodne, zastosowanie pochodnej galantaminy do wytwarzania środków leczniczych, sposób wytwarzania środków leczniczych oraz sposób oddzielania (+)- i (-)-izomerów |
| DE10129265A1 (de) * | 2001-06-18 | 2003-01-02 | Hf Arzneimittelforsch Gmbh | Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie |
| DE10134038A1 (de) * | 2001-07-12 | 2003-02-06 | Hf Arzneimittelforsch Gmbh | Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit |
| CN1646536A (zh) * | 2002-03-25 | 2005-07-27 | 萨诺化学萨物股份公司 | 制备降雪花胺以及其异构体、盐和水合物的方法 |
| CA2506282A1 (en) * | 2003-09-29 | 2005-04-07 | Sanochemia Pharmazeutika Ag | Use of galanthamine and the derivatives thereof in the production of medicaments |
| AT414125B (de) * | 2003-09-29 | 2006-09-15 | Sanochemia Pharmazeutika Ag | Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln |
| WO2005065661A2 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Immediate, controlled and sustained release formulations of galanthamine |
| WO2005065662A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Solid dosage formulations of galantamine |
| WO2006124584A2 (en) * | 2005-05-13 | 2006-11-23 | Alza Corporation | Multilayer drug delivery system with barrier against reservoir material flow |
| WO2007035941A2 (en) * | 2005-09-23 | 2007-03-29 | Alza Corporation | Transdermal galantamine delivery system |
| WO2010029554A1 (en) | 2008-09-11 | 2010-03-18 | I.B.R. Israeli Biotechnology Research Ltd. | Leucojum bulb extracts and use thereof |
| US20120129838A1 (en) * | 2009-04-24 | 2012-05-24 | The Industry & Academic Cooperation In Chungnam National University | Composition for Preventing and Treating Alopecia Disorder Containing Morgalanthamine Compounds as an Active Ingredient |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663318A (en) * | 1986-01-15 | 1987-05-05 | Bonnie Davis | Method of treating Alzheimer's disease |
| US4735169A (en) * | 1986-09-03 | 1988-04-05 | Nordson Corporation | Adhesive applicator assembly |
| JP2755403B2 (ja) * | 1987-05-04 | 1998-05-20 | デイービス、ボニー | アルツハイマー病の治療のための化合物 |
| US5336675A (en) * | 1991-05-14 | 1994-08-09 | Ernir Snorrason | Method of treating mania in humans |
| US6323195B1 (en) * | 1993-10-15 | 2001-11-27 | Aventis Pharmaceuticals Inc. | Galanthamine derivatives as acetylcholinesterase inhibitors |
| US5428159A (en) * | 1994-04-08 | 1995-06-27 | Ciba-Geigy Corporation | Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine |
-
1995
- 1995-07-19 GB GBGB9514821.9A patent/GB9514821D0/en active Pending
-
1996
- 1996-07-19 WO PCT/FR1996/001139 patent/WO1997003987A1/fr not_active Ceased
- 1996-07-19 PT PT96926431T patent/PT839149E/pt unknown
- 1996-07-19 DK DK96926431T patent/DK0839149T3/da active
- 1996-07-19 US US08/983,309 patent/US5958903A/en not_active Expired - Lifetime
- 1996-07-19 CA CA2227235A patent/CA2227235C/fr not_active Expired - Fee Related
- 1996-07-19 IL IL12273996A patent/IL122739A0/xx unknown
- 1996-07-19 AU AU66623/96A patent/AU6662396A/en not_active Abandoned
- 1996-07-19 AT AT96926431T patent/ATE264332T1/de active
- 1996-07-19 JP JP50637297A patent/JP4177894B2/ja not_active Expired - Fee Related
- 1996-07-19 ES ES96926431T patent/ES2218596T3/es not_active Expired - Lifetime
- 1996-07-19 MX MX9800407A patent/MX9800407A/es unknown
- 1996-07-19 ZA ZA9606163A patent/ZA966163B/xx unknown
- 1996-07-19 DE DE69632194T patent/DE69632194T2/de not_active Expired - Lifetime
- 1996-07-19 EP EP96926431A patent/EP0839149B9/fr not_active Expired - Lifetime
-
1998
- 1998-01-16 NO NO980215A patent/NO980215L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69632194D1 (de) | 2004-05-19 |
| EP0839149B9 (fr) | 2005-03-09 |
| AU6662396A (en) | 1997-02-18 |
| NO980215D0 (no) | 1998-01-16 |
| MX9800407A (es) | 1998-04-30 |
| GB9514821D0 (en) | 1995-09-20 |
| ZA966163B (en) | 1997-02-10 |
| CA2227235A1 (fr) | 1997-02-06 |
| PT839149E (pt) | 2004-08-31 |
| JPH11509541A (ja) | 1999-08-24 |
| IL122739A0 (en) | 1998-08-16 |
| ES2218596T3 (es) | 2004-11-16 |
| ATE264332T1 (de) | 2004-04-15 |
| CA2227235C (fr) | 2010-08-31 |
| EP0839149B1 (fr) | 2004-04-14 |
| NO980215L (no) | 1998-01-16 |
| WO1997003987A1 (fr) | 1997-02-06 |
| US5958903A (en) | 1999-09-28 |
| DE69632194T2 (de) | 2005-03-17 |
| JP4177894B2 (ja) | 2008-11-05 |
| EP0839149A1 (fr) | 1998-05-06 |
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