DK0839153T3 - Fremgangsmåde til fremstilling af peptider og N-carbamoyl-beskyttede peptider - Google Patents

Fremgangsmåde til fremstilling af peptider og N-carbamoyl-beskyttede peptider

Info

Publication number
DK0839153T3
DK0839153T3 DK96923933T DK96923933T DK0839153T3 DK 0839153 T3 DK0839153 T3 DK 0839153T3 DK 96923933 T DK96923933 T DK 96923933T DK 96923933 T DK96923933 T DK 96923933T DK 0839153 T3 DK0839153 T3 DK 0839153T3
Authority
DK
Denmark
Prior art keywords
peptides
preparation
carbamoyl protected
carbamoyl
protected peptides
Prior art date
Application number
DK96923933T
Other languages
English (en)
Inventor
Andreas Bommarius
Karlheinz Drauz
Uwe Eichhorn
Hans-Dieter Jakubke
Matthias Kottenhahn
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19607100A external-priority patent/DE19607100C2/de
Application filed by Degussa filed Critical Degussa
Application granted granted Critical
Publication of DK0839153T3 publication Critical patent/DK0839153T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK96923933T 1995-07-11 1996-06-26 Fremgangsmåde til fremstilling af peptider og N-carbamoyl-beskyttede peptider DK0839153T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19524710 1995-07-11
DE19603844 1996-02-05
DE19607100A DE19607100C2 (de) 1995-07-11 1996-02-26 Verfahren zur Herstellung von Peptiden und N-Carbamoyl-geschützten Peptiden
PCT/EP1996/002782 WO1997003091A1 (de) 1995-07-11 1996-06-26 Verfahren zur herstellung von peptiden und n-carbamoyl-geschützten peptiden

Publications (1)

Publication Number Publication Date
DK0839153T3 true DK0839153T3 (da) 2001-11-05

Family

ID=27215260

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96923933T DK0839153T3 (da) 1995-07-11 1996-06-26 Fremgangsmåde til fremstilling af peptider og N-carbamoyl-beskyttede peptider

Country Status (11)

Country Link
US (1) US6251625B1 (da)
EP (1) EP0839153B1 (da)
JP (1) JPH11508452A (da)
CN (1) CN1190406A (da)
AR (1) AR002798A1 (da)
AT (1) ATE204291T1 (da)
AU (1) AU6416596A (da)
CA (1) CA2227732A1 (da)
DK (1) DK0839153T3 (da)
ES (1) ES2160827T3 (da)
WO (1) WO1997003091A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19903268A1 (de) * 1999-01-28 2000-08-03 Degussa Verfahren zur Decarbamoylierung von N-carbamoylgeschützten Verbindungen, neue Carbonsäureanhydride und deren Verwendung
CN1939529A (zh) * 2002-01-29 2007-04-04 Wyeth公司 用于调节连接蛋白半通道的组合物和方法
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US7491699B2 (en) * 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
WO2004060791A1 (en) 2003-01-07 2004-07-22 Ramot At Tel Aviv University Ltd. Peptide nanostructures encapsulating a foreign material and method of manufacturing same
CN101415724B (zh) 2003-06-30 2015-12-02 特拉维夫大学未来科技开发有限公司 肽、抗肽抗体以及用它们来诊断和治疗淀粉样蛋白相关疾病的方法
EP1663199B1 (en) * 2003-09-25 2013-04-03 Tel Aviv University Future Technology Development L.P. Compositions and methods using same for treating amyloid-associated diseases
WO2005031362A2 (en) * 2003-10-02 2005-04-07 Ramot At Tel Aviv University Ltd. Novel antibacterial agents and methods of identifying and utilizing same
WO2006006172A2 (en) * 2004-07-15 2006-01-19 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
WO2006013552A2 (en) * 2004-08-02 2006-02-09 Ramot At Tel Aviv University Ltd. Articles of peptide nanostructures and method of forming the same
EP1793816B1 (en) 2004-08-19 2012-01-04 Tel Aviv University Future Technology Development L.P. Compositions for treating amyloid associated diseases
US7786086B2 (en) 2004-09-08 2010-08-31 Ramot At Tel-Aviv University Ltd. Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
US10004828B2 (en) * 2005-10-11 2018-06-26 Romat at Tel-Aviv University Ltd. Self-assembled Fmoc-ff hydrogels
US7879212B2 (en) * 2005-11-03 2011-02-01 Ramot At Tel-Aviv University Ltd. Peptide nanostructure-coated electrodes
US20100020756A1 (en) * 2008-07-24 2010-01-28 Adapt4, Llc Dynamically transformed channel set quality of service
JP5652159B2 (ja) 2009-11-30 2015-01-14 住友化学株式会社 ５−（アミノメチル）−２−クロロチアゾールの製造方法
CN102796165B (zh) * 2011-05-24 2014-02-26 首都医科大学 京都酚逆序列修饰的脂肪胺/醇衍生物及其制备方法和应用
CN109896980B (zh) * 2017-12-07 2022-04-08 浙江九洲药业股份有限公司 一种西格列汀中间体的生物合成方法
JP6564539B1 (ja) 2018-09-14 2019-08-21 長瀬産業株式会社 スルホン酸化合物によるペプチド精製方法
JP2024510435A (ja) 2021-03-18 2024-03-07 シージェン インコーポレイテッド 生体活性化合物の内部移行複合体からの選択的薬物放出

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607194A1 (de) * 1986-03-05 1987-09-10 Merck Patent Gmbh Carbamoylphenothiazine
US5350681A (en) * 1986-08-18 1994-09-27 The Coca-Cola Company Enzymatic membrane method for the synthesis and separation of peptides
GB8621377D0 (en) * 1986-09-04 1986-10-15 Celltech Ltd Enzymatic process
DE4214157C1 (da) * 1992-04-29 1993-08-05 Degussa Ag, 6000 Frankfurt, De
EP1568778A1 (en) * 1992-06-30 2005-08-31 Smithkline Beecham Plc Hydantoinase from agrobacterium
DE4316928C2 (de) * 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
DE19519717C1 (de) * 1995-05-30 1996-08-22 Degussa Neuer Mikroorganismus, dessen Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren

Also Published As

Publication number Publication date
CN1190406A (zh) 1998-08-12
ATE204291T1 (de) 2001-09-15
AR002798A1 (es) 1998-04-29
AU6416596A (en) 1997-02-10
ES2160827T3 (es) 2001-11-16
WO1997003091A1 (de) 1997-01-30
JPH11508452A (ja) 1999-07-27
EP0839153A1 (de) 1998-05-06
US6251625B1 (en) 2001-06-26
EP0839153B1 (de) 2001-08-16
CA2227732A1 (en) 1997-01-30

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