DK0842174T3 - Heterocykliske forbindelser til behandling af myocardisk iskæmi - Google Patents

Heterocykliske forbindelser til behandling af myocardisk iskæmi

Info

Publication number: DK0842174T3
Authority: DK; Denmark
Prior art keywords: pct; optionally branched; compounds; treatment; sec
Prior art date: 1995-07-26

Application number

DK96927083T

Other languages

English (en)

Inventor

Jean-Pierre Rieu

Jean-Francois Patoiseau

W John Gareth

Bruno Legrand

Jean-Pierre Valentin

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-26

Filing date

1996-07-25

Publication date

2002-01-28

1996-07-25 Application filed by Pf Medicament filed Critical Pf Medicament

2002-01-28 Application granted granted Critical

2002-01-28 Publication of DK0842174T3 publication Critical patent/DK0842174T3/da

Links

150000002391 heterocyclic compounds Chemical class 0.000 title 1
208000031225 myocardial ischemia Diseases 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
-1 nitro, hydroxy Chemical group 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Substances 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Hydrogenated Pyridines (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK96927083T 1995-07-26 1996-07-25 Heterocykliske forbindelser til behandling af myocardisk iskæmi DK0842174T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9509079A FR2737207B1 (fr)	1995-07-26	1995-07-26	Nouvelles n-heterocyclyl-1-aryloxyalcoyl-4-piperidinamines substituees, leur preparation et leur application en therapeutique
PCT/FR1996/001176 WO1997005134A1 (fr)	1995-07-26	1996-07-25	Composes heterocycliques pour le traitement de l'ischemie myocardique

Publications (1)

Publication Number	Publication Date
DK0842174T3 true DK0842174T3 (da)	2002-01-28

Family

ID=9481394

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96927083T DK0842174T3 (da)	1995-07-26	1996-07-25	Heterocykliske forbindelser til behandling af myocardisk iskæmi

Country Status (17)

Country	Link
US (1)	US6011032A (da)
EP (1)	EP0842174B1 (da)
JP (1)	JPH11509857A (da)
KR (1)	KR19990035986A (da)
CN (1)	CN1103338C (da)
AT (1)	ATE206423T1 (da)
AU (1)	AU707950B2 (da)
BR (1)	BR9609911A (da)
CA (1)	CA2228691A1 (da)
DE (1)	DE69615696T2 (da)
DK (1)	DK0842174T3 (da)
ES (1)	ES2165514T3 (da)
FR (1)	FR2737207B1 (da)
MX (1)	MX9800705A (da)
NZ (1)	NZ315347A (da)
PT (1)	PT842174E (da)
WO (1)	WO1997005134A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2788771B1 (fr) *	1999-01-22	2001-04-13	Pf Medicament	Nouvelles 1,2-alcoyl-1-[1-[aryl (alcoyl) oxyalcoyl] piperidin-4-yl]-3-aryl isothiourees substituees, leur preparation et leur application en therapeutique
FR2788775B1 (fr) *	1999-01-22	2001-04-13	Pf Medicament	Nouvelles n-alcoyl-n-[1-(omega-(arylalcoyloxy)alcoyl] piperidin-4-yl]-4h-3,1-benzo(thia/oxa)zines-2-amines substituees, leur preparation et leur application en therapeutique
WO2000066579A1 (en) *	1999-04-28	2000-11-09	Banyu Pharmaceutical Co., Ltd.	Processes for the preparation of piperidylmethylpyridine derivatives
FR3001151B1 (fr)	2013-01-21	2016-04-08	Pf Medicament	Association d'un bloqueur de courant sodique lent et d'un inhibiteur du courant if sinusal et les compositions pharmarceutiques la contenant
CN114349745B (zh) *	2022-01-14	2023-12-08	黑龙江中医药大学	一种用于治疗心肌缺血的药物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1260474A (en) *	1984-12-03	1989-09-26	Raymond A. Stokbroekx	Benzoxazol- and benzothiazolamine derivatives

1995
- 1995-07-26 FR FR9509079A patent/FR2737207B1/fr not_active Expired - Fee Related
1996
- 1996-07-25 DK DK96927083T patent/DK0842174T3/da active
- 1996-07-25 AU AU67031/96A patent/AU707950B2/en not_active Ceased
- 1996-07-25 PT PT96927083T patent/PT842174E/pt unknown
- 1996-07-25 CN CN96196566A patent/CN1103338C/zh not_active Expired - Fee Related
- 1996-07-25 EP EP96927083A patent/EP0842174B1/fr not_active Expired - Lifetime
- 1996-07-25 DE DE69615696T patent/DE69615696T2/de not_active Expired - Fee Related
- 1996-07-25 US US09/011,207 patent/US6011032A/en not_active Expired - Fee Related
- 1996-07-25 ES ES96927083T patent/ES2165514T3/es not_active Expired - Lifetime
- 1996-07-25 BR BR9609911A patent/BR9609911A/pt not_active IP Right Cessation
- 1996-07-25 WO PCT/FR1996/001176 patent/WO1997005134A1/fr not_active Ceased
- 1996-07-25 CA CA002228691A patent/CA2228691A1/fr not_active Abandoned
- 1996-07-25 KR KR1019980700648A patent/KR19990035986A/ko not_active Ceased
- 1996-07-25 JP JP9507283A patent/JPH11509857A/ja active Pending
- 1996-07-25 AT AT96927083T patent/ATE206423T1/de not_active IP Right Cessation
- 1996-07-25 NZ NZ315347A patent/NZ315347A/xx unknown
1998
- 1998-01-23 MX MX9800705A patent/MX9800705A/es active IP Right Grant

Also Published As

Publication number	Publication date
FR2737207A1 (fr)	1997-01-31
AU6703196A (en)	1997-02-26
BR9609911A (pt)	1999-03-02
EP0842174A1 (fr)	1998-05-20
ES2165514T3 (es)	2002-03-16
JPH11509857A (ja)	1999-08-31
NZ315347A (en)	2000-01-28
KR19990035986A (ko)	1999-05-25
WO1997005134A1 (fr)	1997-02-13
MX9800705A (es)	1998-10-31
PT842174E (pt)	2002-03-28
ATE206423T1 (de)	2001-10-15
CN1103338C (zh)	2003-03-19
FR2737207B1 (fr)	1997-10-17
CA2228691A1 (fr)	1997-02-13
AU707950B2 (en)	1999-07-22
EP0842174B1 (fr)	2001-10-04
US6011032A (en)	2000-01-04
DE69615696D1 (de)	2001-11-08
CN1193972A (zh)	1998-09-23
DE69615696T2 (de)	2002-07-11

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YU49122B (sh)	2004-03-12	Supstituisana benzilaminopiperidinska jedinjenja
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ATE278322T1 (de)	2004-10-15	Mittel zur bekämpfung von pflanzenschädlingen
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DE69607650D1 (de)	2000-05-11	2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendung
BR9612216A (pt)	1999-12-28	Processo para preparar um composto derivado de piperidina, regioisómero, processo para preparar um regioisómero, derivado de alfa, alfa- di-substituído, e alfa,alfa-di não substituído metilbenzeno, derivado de oxobutila, precursor de derivado de piperidina e processo para tratar reações alérgicas em um paciente.
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ATE206423T1 (de)	2001-10-15	Heterocyclische verbindungen zur behandlung von myokard-ischemia
ES2177816T3 (es)	2002-12-16	Derivados de azahexano como isosteros de sustrato de aspartato proteasas retroviricas.
BR9913757A (pt)	2001-10-09	Composto, e, agentes controladores de praga
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DK0819108T3 (da)	2001-11-26	Fremgangsmåde til fremstilling af galanthaminderivater ved asymmetrisk reduktion
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EE200300090A (et)	2004-12-15	Asendatud imidasopüridiinühendite valmistamise meetod
PT100682A (pt)	1993-08-31	Agentes anti-helminticos derivados de benzimidazole e processo para a sua preparacao
EA199800931A1 (ru)	1999-04-29	Способ получения ингибиторов фосфодиэстеразы iv
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DE3671014D1 (de)	1990-06-13	Cyclohexan-1,3-dionderivate, diese enthaltende zusammensetzungen, verfahren zu deren herstellung und deren verwendung als herbizide und pflanzenwachstumsregulatoren.
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