DK0843547T3 - Fremgangsmåder til at fremstille liposomer, der indeholder hydromonobenzoporphyrin- fotosensibilisatorer - Google Patents

Fremgangsmåder til at fremstille liposomer, der indeholder hydromonobenzoporphyrin- fotosensibilisatorer

Info

Publication number
DK0843547T3
DK0843547T3 DK96925614T DK96925614T DK0843547T3 DK 0843547 T3 DK0843547 T3 DK 0843547T3 DK 96925614 T DK96925614 T DK 96925614T DK 96925614 T DK96925614 T DK 96925614T DK 0843547 T3 DK0843547 T3 DK 0843547T3
Authority
DK
Denmark
Prior art keywords
photosensitizers
hydromonobenzoporphyrin
methods
liposomes containing
preparing liposomes
Prior art date
Application number
DK96925614T
Other languages
Danish (da)
English (en)
Inventor
Liu Ron
Original Assignee
Quadra Logic Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadra Logic Tech Inc filed Critical Quadra Logic Tech Inc
Application granted granted Critical
Publication of DK0843547T3 publication Critical patent/DK0843547T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK96925614T 1995-08-02 1996-07-29 Fremgangsmåder til at fremstille liposomer, der indeholder hydromonobenzoporphyrin- fotosensibilisatorer DK0843547T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/510,573 US5707608A (en) 1995-08-02 1995-08-02 Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizer
PCT/CA1996/000512 WO1997004746A1 (en) 1995-08-02 1996-07-29 Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizers

Publications (1)

Publication Number Publication Date
DK0843547T3 true DK0843547T3 (da) 2003-02-24

Family

ID=24031289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96925614T DK0843547T3 (da) 1995-08-02 1996-07-29 Fremgangsmåder til at fremstille liposomer, der indeholder hydromonobenzoporphyrin- fotosensibilisatorer

Country Status (12)

Country Link
US (1) US5707608A (de)
EP (1) EP0843547B1 (de)
JP (1) JP3782112B2 (de)
AT (1) ATE226430T1 (de)
AU (1) AU717181B2 (de)
CA (1) CA2227761C (de)
DE (1) DE69624485T2 (de)
DK (1) DK0843547T3 (de)
ES (1) ES2186792T3 (de)
PT (1) PT843547E (de)
TW (1) TW585785B (de)
WO (1) WO1997004746A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0732106A3 (de) * 1991-03-22 2003-04-09 Katsuro Tachibana Mikrobläschen enthaltende Verstärker zur Ultraschalltherapie von Erkrankungen
US6890555B1 (en) * 1992-02-05 2005-05-10 Qlt, Inc. Liposome compositions of porphyrin photosensitizers
US6210356B1 (en) * 1998-08-05 2001-04-03 Ekos Corporation Ultrasound assembly for use with a catheter
US6176842B1 (en) 1995-03-08 2001-01-23 Ekos Corporation Ultrasound assembly for use with light activated drugs
US6143287A (en) * 1996-02-27 2000-11-07 New York Blood Center, Inc. Method and composition for hair removal
CA2202103C (en) * 1996-04-11 2007-01-09 Toshiaki Tagawa Method for preparing closed vesicles
JP2001511128A (ja) * 1997-01-28 2001-08-07 ファルマシア・アンド・アップジョン・カンパニー 水不溶性ポルフィリンの脂質錯体の凍結乾燥物
US6582392B1 (en) * 1998-05-01 2003-06-24 Ekos Corporation Ultrasound assembly for use with a catheter
US6676626B1 (en) 1998-05-01 2004-01-13 Ekos Corporation Ultrasound assembly with increased efficacy
WO1999013916A2 (en) * 1997-09-18 1999-03-25 Nycomed Imaging As Methods and compositions for medical imaging
US6183727B1 (en) 1998-05-19 2001-02-06 Arizona Board Of Regents Use of long-wavelength electromagnetic radiation and photoprotective tumor localizing agents for diagnosis
US6608050B2 (en) * 1999-07-20 2003-08-19 Pharmacia & Upjohn Company Lyophilizate of lipid complex of water insoluble porphyrins
US6944493B2 (en) * 1999-09-10 2005-09-13 Akora, Inc. Indocyanine green (ICG) compositions and related methods of use
US6351663B1 (en) 1999-09-10 2002-02-26 Akorn, Inc. Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation
US6443976B1 (en) 1999-11-30 2002-09-03 Akorn, Inc. Methods for treating conditions and illnesses associated with abnormal vasculature
WO2001058240A2 (en) 2000-02-10 2001-08-16 Massachusetts Eye And Ear Infirmary Photodynamic therapy for treating conditions of the eye
IL151833A0 (en) * 2000-03-24 2003-04-10 Novartis Ag Improved treatment of neovascularization
WO2002064163A2 (en) 2001-02-15 2002-08-22 Qlt Inc. Reduction or prevention of pdt related inflammation
AU2007202603B2 (en) * 2001-04-11 2010-06-10 Valeant Pharmaceuticals International, Inc. Drug delivery system for hydrophobic drugs
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
EP1465590B1 (de) * 2001-11-02 2008-03-26 The Governors Of The University Of Alberta Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator
US7220239B2 (en) 2001-12-03 2007-05-22 Ekos Corporation Catheter with multiple ultrasound radiating members
US8226629B1 (en) 2002-04-01 2012-07-24 Ekos Corporation Ultrasonic catheter power control
US7455858B2 (en) * 2002-05-16 2008-11-25 Qlt Inc. Compositions and methods for delivery of photosensitive drugs
US6921371B2 (en) * 2002-10-14 2005-07-26 Ekos Corporation Ultrasound radiating members for catheter
US20040220167A1 (en) * 2003-05-02 2004-11-04 Nasrollah Samiy Methods of treating neuralgic pain
US7682603B2 (en) * 2003-07-25 2010-03-23 The Trustees Of The University Of Pennsylvania Polymersomes incorporating highly emissive probes
US20050048109A1 (en) * 2003-08-26 2005-03-03 Ceramoptec Industries, Inc. Non-polar photosensitizer formulations for photodynamic therapy
US7341569B2 (en) * 2004-01-30 2008-03-11 Ekos Corporation Treatment of vascular occlusions using ultrasonic energy and microbubbles
US7419666B1 (en) 2004-02-23 2008-09-02 Massachusetts Eye And Ear Infirmary Treatment of ocular disorders
JP2008536562A (ja) * 2005-04-12 2008-09-11 イコス コーポレイション 空洞形成推進面が設けられた超音波カテーテル
EP2015846A2 (de) 2006-04-24 2009-01-21 Ekos Corporation Ultraschalltherapiesystem
US10182833B2 (en) 2007-01-08 2019-01-22 Ekos Corporation Power parameters for ultrasonic catheter
WO2008088037A1 (ja) * 2007-01-18 2008-07-24 National University Corporation Chiba University 微粒子製剤
ES2471118T3 (es) 2007-06-22 2014-06-25 Ekos Corporation Método y aparato para el tratamiento de hemorragias intracraneales
WO2009079415A1 (en) * 2007-12-14 2009-06-25 Ekos Corporation Ultrasound pulse shaping
US9211214B2 (en) 2012-03-21 2015-12-15 Valeant Pharmaceuticals International, Inc Photodynamic therapy laser
US10918599B2 (en) * 2015-04-02 2021-02-16 The Research Foundation For The State University Of New York Serum-stable compositions and methods for light-triggered release of materials
EP3307388B1 (de) 2015-06-10 2022-06-22 Ekos Corporation Ultraschallkatheter
KR102434879B1 (ko) 2016-05-26 2022-08-22 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 폐혈관 질환 치료용 조성물 및 방법
KR102035384B1 (ko) * 2017-06-26 2019-10-22 서강대학교산학협력단 광감작제를 포함한 마이크로버블-나노입자 복합체 및 이를 포함하는 항암 치료제

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500507A (en) * 1981-10-30 1985-02-19 Wong Dennis W Diagnostic composition for radiologic imaging of neoplasms in the body and method of preparation
US4649151A (en) * 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins
US4577636A (en) * 1982-11-23 1986-03-25 The Beth Israel Hospital Association Method for diagnosis of atherosclerosis
US4517762A (en) * 1983-07-08 1985-05-21 Venetz Louis M Animal trap holder
US4485806A (en) * 1983-10-24 1984-12-04 Calspan Corporation Method and apparatus for evacuating contaminated casualties
US4753958A (en) * 1985-02-07 1988-06-28 University Of Cal Photochemotherapy of epithelial diseases with derivatives of hematoporphyrins
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
US4933121A (en) * 1986-12-10 1990-06-12 Ciba Corning Diagnostics Corp. Process for forming liposomes
US4920143A (en) * 1987-04-23 1990-04-24 University Of British Columbia Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US4883790A (en) * 1987-01-20 1989-11-28 University Of British Columbia Wavelength-specific cytotoxic agents
US5010073A (en) * 1989-10-05 1991-04-23 The Rockefeller University Use of liposomes as carriers for metalloporphyrins
US5214036A (en) * 1990-03-08 1993-05-25 University Of British Columbia Benzoporphyrin derivatives for photodynamic therapy
US5238940A (en) * 1990-03-22 1993-08-24 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
US5053423A (en) * 1990-03-22 1991-10-01 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
US5270053A (en) * 1990-04-03 1993-12-14 Ciba-Geigy Corp. Parenterally administerable liposome formulation comprising synthetic lipid
CA2047969A1 (en) * 1990-08-17 1992-02-18 Thomas D. Madden Benzoporphyrin vesicles
CA2087902C (en) * 1992-02-05 2006-10-17 Narendra Raghunathji Desai Liposome compositions of porphyrin photosensitizers
US5422362A (en) * 1993-07-29 1995-06-06 Quadra Logic Technologies, Inc. Method to inhibit restenosis

Also Published As

Publication number Publication date
AU717181B2 (en) 2000-03-16
JP3782112B2 (ja) 2006-06-07
DE69624485T2 (de) 2003-06-26
WO1997004746A1 (en) 1997-02-13
PT843547E (pt) 2003-03-31
ES2186792T3 (es) 2003-05-16
TW585785B (en) 2004-05-01
CA2227761C (en) 2004-01-06
AU6608396A (en) 1997-02-26
EP0843547B1 (de) 2002-10-23
US5707608A (en) 1998-01-13
CA2227761A1 (en) 1997-02-13
DE69624485D1 (de) 2002-11-28
EP0843547A1 (de) 1998-05-27
ATE226430T1 (de) 2002-11-15

Similar Documents

Publication Publication Date Title
DK0843547T3 (da) Fremgangsmåder til at fremstille liposomer, der indeholder hydromonobenzoporphyrin- fotosensibilisatorer
TR200102338T2 (tr) Siklik ikame edilmiş bağlı pirolokarbazoller ve izoindolonlar.
BG103251A (bg) Оксадиазоли, методи за получаването им и приложението им като лекарствени средства
DK0758248T3 (da) Formuleringer til faktor IX
IE830227L (en) Pyrazolooxazines
GT199900019A (es) Formulas farmaceuticamente estables de solucion de oxaliplatino.
GR900100380A (el) Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.
PH15562A (en) New hydroxyethyl-azole compounds,their production and their medicinal use
NO20013862D0 (no) Fremgangsmate for a regulere liposomstorrelse
GR3018810T3 (en) 5,6-dihydroxyindoline as additives for hair-dyeing preparations.
DE59208974D1 (de) Neue pyrazinderivative, ihre herstellung und verwendung
AU536920B2 (en) Hydroxypropyl-triazole derivatives and their use as antimycotic agents
MX9702666A (es) Nuevos peptidos con efectos inmunoreguladores.
TR199800608A2 (en) Propanolamin t�revleri, bunlar�n �retim usul�.
ATE233484T1 (de) Desinfizierende zusammensetzung
AU5933080A (en) 1-alkadienyl-2hydroxymethyl-3,4,5-trihydroxy- piperidine compounds
JPS55160712A (en) Emulsified cosmetic composition
ID27440A (id) Proses untuk menyiapkan penengah-penengah
ATE70060T1 (de) Neue tetrahydro-benzothiazole, ihre herstellung und verwendung.
ES2060050T3 (es) Beta-tioacrilamidas s-sustituidas y su uso como microbicidas.
ES8200871A1 (es) Procedimiento para la obtencion de derivados de 2-amino-3,4-dihidropiridina
DE3851842D1 (de) Wässrige bereitung von liposomenzusammensetzungen.
BR9808210A (pt) Befeniloxazolinas dissubstituìdas
TR200000154T2 (tr) 2,4,4-Trisübstitüe-1,3-Dioksolan mantar önleyiciler.
SE9803107D0 (sv) Novel Compunds