DK0846948T3 - Mediatorer, der er egnede i en elektrokemisk biosensor - Google Patents

Mediatorer, der er egnede i en elektrokemisk biosensor

Info

Publication number
DK0846948T3
DK0846948T3 DK97120715T DK97120715T DK0846948T3 DK 0846948 T3 DK0846948 T3 DK 0846948T3 DK 97120715 T DK97120715 T DK 97120715T DK 97120715 T DK97120715 T DK 97120715T DK 0846948 T3 DK0846948 T3 DK 0846948T3
Authority
DK
Denmark
Prior art keywords
electrochemical biosensor
mediators
nadh
nadph
useful
Prior art date
Application number
DK97120715T
Other languages
English (en)
Inventor
Horst Berneth
Thomas Bocker
Henry Giera
Alison J Murray
Hans-Ulrich Siegmund
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0846948T3 publication Critical patent/DK0846948T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Hybrid Cells (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Secondary Cells (AREA)
DK97120715T 1996-12-09 1997-11-26 Mediatorer, der er egnede i en elektrokemisk biosensor DK0846948T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/762,098 US5866353A (en) 1996-12-09 1996-12-09 Electro chemical biosensor containing diazacyanine mediator for co-enzyme regeneration

Publications (1)

Publication Number Publication Date
DK0846948T3 true DK0846948T3 (da) 2004-07-12

Family

ID=25064127

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97120715T DK0846948T3 (da) 1996-12-09 1997-11-26 Mediatorer, der er egnede i en elektrokemisk biosensor

Country Status (9)

Country Link
US (1) US5866353A (da)
EP (1) EP0846948B1 (da)
JP (1) JP3966591B2 (da)
AT (1) ATE262174T1 (da)
AU (1) AU726868B2 (da)
CA (1) CA2224034C (da)
DE (1) DE69728115T2 (da)
DK (1) DK0846948T3 (da)
ES (1) ES2216096T3 (da)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6500571B2 (en) 1998-08-19 2002-12-31 Powerzyme, Inc. Enzymatic fuel cell
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
DE60239132D1 (de) 2001-06-12 2011-03-24 Pelikan Technologies Inc Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
EP1404232B1 (en) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Blood sampling apparatus and method
ATE485766T1 (de) 2001-06-12 2010-11-15 Pelikan Technologies Inc Elektrisches betätigungselement für eine lanzette
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
JP4209767B2 (ja) 2001-06-12 2009-01-14 ペリカン テクノロジーズ インコーポレイテッド 皮膚の性状の一時的変化に対する適応手段を備えた自動最適化形切開器具
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
ATE494837T1 (de) 2001-06-12 2011-01-15 Pelikan Technologies Inc Integriertes system zur blutprobenanalyse mit mehrfach verwendbarem probennahmemodul
US6787013B2 (en) * 2001-09-10 2004-09-07 Eumed Biotechnology Co., Ltd. Biosensor
FR2829926B1 (fr) * 2001-09-26 2004-10-01 Oreal Composition pour la teinture des fibres keratiniques comprenant un colorant diazoique dicationique particulier
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
GB0204232D0 (en) * 2002-02-22 2002-04-10 Isis Innovation Assay
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7524293B2 (en) 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7244265B2 (en) 2002-04-19 2007-07-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) * 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7648468B2 (en) * 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
WO2003088824A2 (en) 2002-04-19 2003-10-30 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7331931B2 (en) * 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7485128B2 (en) 2002-04-19 2009-02-03 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7265881B2 (en) * 2002-12-20 2007-09-04 Hewlett-Packard Development Company, L.P. Method and apparatus for measuring assembly and alignment errors in sensor assemblies
US8574895B2 (en) * 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
EP2238892A3 (en) 2003-05-30 2011-02-09 Pelikan Technologies Inc. Apparatus for body fluid sampling
ES2490740T3 (es) 2003-06-06 2014-09-04 Sanofi-Aventis Deutschland Gmbh Aparato para toma de muestras de fluido sanguíneo y detección de analitos
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7604592B2 (en) 2003-06-13 2009-10-20 Pelikan Technologies, Inc. Method and apparatus for a point of care device
CA2448618A1 (en) * 2003-09-11 2005-03-11 Amer Hammami New 2,2'-azino-bis-thiazolines as precursors to air-stable radicals
EP1671096A4 (en) 2003-09-29 2009-09-16 Pelikan Technologies Inc METHOD AND APPARATUS FOR PROVIDING IMPROVED SAMPLE CAPTURING DEVICE
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9820684B2 (en) 2004-06-03 2017-11-21 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US9775553B2 (en) * 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
AU2005295106B2 (en) 2004-10-12 2012-03-15 Bayer Healthcare Llc Concentration determination in a diffusion barrier layer
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
JP2011511665A (ja) 2008-02-04 2011-04-14 バイエル・ヘルスケア・エルエルシー 半導体を素材とする分析対象物センサー及び方法
US8008037B2 (en) * 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
CA2735666A1 (en) * 2008-09-19 2010-03-25 Bayer Healthcare Llc Analyte sensors, testing apparatus and manufacturing methods
CA2735675C (en) 2008-09-19 2017-02-14 Bayer Healthcare Llc Electrochemical devices with enhanced electrochemical activity and manufacturing methods thereof
EP2341830A4 (en) 2008-09-19 2012-10-31 Bayer Healthcare Llc ANALYTICAL SENSORS, SYSTEMS, TEST UNIT AND MANUFACTURING METHOD
WO2010033660A1 (en) * 2008-09-19 2010-03-25 Bayer Healthcare Llc Lancet analyte sensors and methods of manufacturing
US20100187132A1 (en) * 2008-12-29 2010-07-29 Don Alden Determination of the real electrochemical surface areas of screen printed electrodes
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
EP3343213B1 (en) * 2009-08-31 2019-10-23 PHC Holdings Corporation Sensor
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
TWI476402B (zh) 2012-08-10 2015-03-11 Univ Ishou 電化學感測器的感測方法
US12091760B2 (en) * 2019-11-08 2024-09-17 Okechukwu Charles Muamba Modified graphite substrates with improved stability

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076266B1 (en) * 1981-04-08 1988-11-09 GORTON, Lo Electrode for the electrochemical regeneration of co-enzyme, a method of making said electrode, and the use thereof
GB8424709D0 (en) * 1984-10-01 1984-11-07 Minnesota Mining & Mfg Azine redox dyes and leuco azine dyes
DE4100810A1 (de) * 1991-01-12 1992-07-16 Bayer Ag Kationische 1,3,4-thiadiazolfarbstoffe
DE4222257A1 (de) * 1992-07-07 1994-01-13 Bayer Ag Kationische Thiadiazoldiphenylaminfarbstoffe
US5393615A (en) * 1994-02-03 1995-02-28 Miles Inc. Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
US5498542A (en) * 1994-09-29 1996-03-12 Bayer Corporation Electrode mediators for regeneration of NADH and NADPH
DE4442253A1 (de) * 1994-11-28 1996-05-30 Bayer Corp N D Ges D Staates I Elektrochemischer Enzymbiosensor
US5520786A (en) * 1995-06-06 1996-05-28 Bayer Corporation Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof

Also Published As

Publication number Publication date
DE69728115T2 (de) 2004-08-26
EP0846948B1 (en) 2004-03-17
US5866353A (en) 1999-02-02
EP0846948A1 (en) 1998-06-10
CA2224034C (en) 2004-02-17
ES2216096T3 (es) 2004-10-16
AU726868B2 (en) 2000-11-23
CA2224034A1 (en) 1998-06-09
DE69728115D1 (de) 2004-04-22
JP3966591B2 (ja) 2007-08-29
ATE262174T1 (de) 2004-04-15
JPH10165199A (ja) 1998-06-23
AU4760297A (en) 1998-06-11

Similar Documents

Publication Publication Date Title
AU4760297A (en) Mediators useful in an electrochemical biosensor
AU674463B2 (en) Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
ATE231652T1 (de) Elektrochemisches verfahren zum erzeugen einer biologischen protontriebkraft und regenerierung des pyridin-nucleotid cofaktors
CA2177753A1 (en) Mediators suitable for the electrochemical regeneration of nadh, nadph or analogs thereof
Hisada et al. 1-methoxy-5-methylphenazinium methyl sulfate: a photochemically stable electron mediator between NADH and various electron acceptors
CA2152410A1 (en) Mediators suitable for the electrochemical regeneration of nadh, nadph or analogs thereof
Kulys et al. Biocatalysis and electrocatalysis at carbon paste electrodes doped by diaphorase‐methylene green and diaphorase‐meldola blue
EP1333524A4 (en) METHOD AND CELL FOR GENERATING ENERGY
Fu et al. Extracellular electron transfer of Shewanella oneidensis MR-1 for cathodic hydrogen evolution reaction
DE502006008961D1 (de) Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen
EE200200646A (et) NAD(P)H kaudset elektrokeemilist regeneratsiooni sisaldav meetod
ATE313789T1 (de) Verfahren zum bestimmen von l-phenylalanin und ein l-phenylalaninsensor
RU96103648A (ru) Биодатчик для обнаружения ионов нитрата или нитрита
Suye et al. Electrochemical reduction of immobilized NADP+ on a polymer modified electrode with a co-polymerized mediator
DK169487D0 (da) Fremstilling af et vitamin c-forstadium under anvendelse af genetisk modificerede organismer
GB1533194A (en) Electrochemical sensor of hydrogen and hydrogen-containing reducing agents
Kulys et al. Recombinant Microdochium nivale carbohydrate oxidase and its application in an amperometric glucose sensor
Takahashi et al. Electrochemical processes in the photoelectrolysis of nicotinamide adenine dinucleotide on the chlorophyll electrodes
JPS5513072A (en) Electrochemical regeneration of coenzyme
Anthony Cytochrome c and the oxidation of C1 compounds in Pseudomonas AM1
JP2556526B2 (ja) 酵素酸化法
ATE458829T1 (de) Stabilisierte coenzym-lösungen und deren verwendung zur bestimmung von dehydrogenasen bzw. deren substrate
Kim et al. Reduction of nitrosoarene by purified NAD (P) H-quinone oxidoreductase
TSE Bioelectrocatalysis using chemically modified electrodes[Ph. D. Thesis]
Kumar et al. Development of anaerobic biofilms on glass surface.