DK0854707T3 - Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof - Google Patents

Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof

Info

Publication number
DK0854707T3
DK0854707T3 DK96934494T DK96934494T DK0854707T3 DK 0854707 T3 DK0854707 T3 DK 0854707T3 DK 96934494 T DK96934494 T DK 96934494T DK 96934494 T DK96934494 T DK 96934494T DK 0854707 T3 DK0854707 T3 DK 0854707T3
Authority
DK
Denmark
Prior art keywords
extrusion
isomal
polymer
active substance
biologically active
Prior art date
Application number
DK96934494T
Other languages
English (en)
Inventor
Juergen Zeidler
Joerg Rosenberg
Joerg Neumann
Joerg Breitenbach
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK0854707T3 publication Critical patent/DK0854707T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DK96934494T 1995-09-29 1996-09-30 Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof DK0854707T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19536394A DE19536394A1 (de) 1995-09-29 1995-09-29 Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze
PCT/EP1996/004262 WO1997012603A1 (de) 1995-09-29 1996-09-30 Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze

Publications (1)

Publication Number Publication Date
DK0854707T3 true DK0854707T3 (da) 2002-12-16

Family

ID=7773633

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96934494T DK0854707T3 (da) 1995-09-29 1996-09-30 Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof

Country Status (22)

Country Link
US (1) US6187342B1 (da)
EP (1) EP0854707B1 (da)
JP (1) JP4041163B2 (da)
KR (1) KR19990063853A (da)
CN (1) CN1200694C (da)
AT (1) ATE228355T1 (da)
AU (1) AU7282896A (da)
BG (1) BG102346A (da)
BR (1) BR9610799A (da)
CA (1) CA2230950C (da)
CZ (1) CZ95998A3 (da)
DE (2) DE19536394A1 (da)
DK (1) DK0854707T3 (da)
ES (1) ES2187678T3 (da)
HU (1) HUP9903384A3 (da)
IL (1) IL123250A (da)
MX (1) MX9801988A (da)
NO (1) NO981394L (da)
RU (1) RU2197228C2 (da)
TW (1) TW438599B (da)
WO (1) WO1997012603A1 (da)
ZA (1) ZA968130B (da)

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DE19809242A1 (de) * 1998-03-05 1999-09-09 Basf Ag Verfahren zur Herstellung von festen, sphärischen Formkörpern, enthaltend pharmazeutische Wirkstoffe in einer Bindemittelmatrix
US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
CA2359945C (en) * 1999-11-12 2011-04-26 Abbott Laboratories Inhibitors of crystallization in a solid dispersion
US20070141107A1 (en) * 2000-03-15 2007-06-21 Orbusneich Medical, Inc. Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) * 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
US7067148B2 (en) * 2001-02-15 2006-06-27 King Pharmaceutical Research & Development, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
EP1372392A4 (en) * 2001-03-26 2004-06-23 Smithkline Beecham Corp ORAL DOSAGE FORM CONTAINING NICOTINE
FR2823974B1 (fr) * 2001-04-25 2004-10-15 Pf Medicament Pastille medicamenteuse a liberation lente du principe actif
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030171436A1 (en) * 2001-10-29 2003-09-11 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
KR100514590B1 (ko) * 2001-12-18 2005-09-14 주식회사 대웅 프라바스타틴나트륨 및 안정화제로서의 코폴리비돈을함유하는 약제 조성물
US20040101543A1 (en) * 2002-03-22 2004-05-27 John Liu Nicotine-containing oral dosage form
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
DE60313359T2 (de) * 2002-12-17 2008-01-03 Abbott Gmbh & Co. Kg Fenofibratsäure enthaltende pharmazeutische zusammensetzung und deren physiologisch verträgliche salze und derivate
JP4783278B2 (ja) * 2003-02-03 2011-09-28 ノバルティス アーゲー 医薬製剤
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
GB2418854B (en) * 2004-08-31 2009-12-23 Euro Celtique Sa Multiparticulates
RU2276985C1 (ru) * 2004-10-07 2006-05-27 Открытое акционерное общество "Щелковский витаминный завод" Фармацевтическая композиция для лечения заболеваний поджелудочной железы и расстройств пищеварения, связанных с заболеванием печени
EP1968542B1 (en) * 2005-12-16 2013-08-14 Hanmi Science Co., Ltd. Solid dispersion comprising an active ingredient having a low melting point and tablet for oral administration comprising same
EP2140861A1 (en) * 2008-06-30 2010-01-06 Abbott GmbH & Co. KG Pharmaceutical dosage form comprising polymeric carrier composition
CA2813510A1 (en) * 2010-10-14 2012-04-19 Abbott Gmbh & Co. Kg Curcuminoid solid dispersion formulation
CA2830765C (en) 2011-03-21 2019-02-05 Boehringer Ingelheim International Gmbh Solid preparation containing ambroxol
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
US20190217531A1 (en) 2016-04-06 2019-07-18 Astellas Pharma Inc. Fast-eluting three-dimensionally molded object, filament for fast-eluting three-dimensionally molded object, and material for fast-eluting three-dimensionally molded object

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1440327A3 (ru) * 1980-07-03 1988-11-23 Тейт Энд Лайл Паблик Лимитед Компани (Фирма) Способ получени таблетированной формы препарата
DE3314003A1 (de) * 1983-04-18 1984-10-18 Boehringer Ingelheim KG, 6507 Ingelheim Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
DE3612211A1 (de) 1986-04-11 1987-10-15 Basf Ag Kontinuierliches verfahren zum tablettieren
DE3826946C1 (da) * 1988-08-09 1990-03-15 A. Nattermann & Cie Gmbh, 5000 Koeln, De
JP4302770B2 (ja) * 1994-06-14 2009-07-29 バイオヴェイル ラボラトリーズ インターナショナル ソシエテ レスポンサビリタ リミタータ 速やかに溶解する投薬単位の製造方法及び装置並びにその製品

Also Published As

Publication number Publication date
JPH11512729A (ja) 1999-11-02
IL123250A (en) 2000-08-31
ES2187678T3 (es) 2003-06-16
EP0854707B1 (de) 2002-11-27
ZA968130B (en) 1998-03-27
DE59609923D1 (de) 2003-01-09
EP0854707A1 (de) 1998-07-29
DE19536394A1 (de) 1997-04-03
HUP9903384A2 (hu) 2000-10-28
HUP9903384A3 (en) 2001-04-28
NO981394D0 (no) 1998-03-27
WO1997012603A1 (de) 1997-04-10
CZ95998A3 (cs) 1998-08-12
CN1200694C (zh) 2005-05-11
CN1198094A (zh) 1998-11-04
JP4041163B2 (ja) 2008-01-30
NO981394L (no) 1998-03-27
KR19990063853A (ko) 1999-07-26
CA2230950A1 (en) 1997-04-10
BR9610799A (pt) 1999-07-13
AU7282896A (en) 1997-04-28
TW438599B (en) 2001-06-07
RU2197228C2 (ru) 2003-01-27
BG102346A (bg) 1998-10-30
IL123250A0 (en) 1998-09-24
MX9801988A (es) 1998-08-30
ATE228355T1 (de) 2002-12-15
US6187342B1 (en) 2001-02-13
CA2230950C (en) 2007-12-04

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