DK0863797T3 - Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek - Google Patents

Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek

Info

Publication number
DK0863797T3
DK0863797T3 DK96935090T DK96935090T DK0863797T3 DK 0863797 T3 DK0863797 T3 DK 0863797T3 DK 96935090 T DK96935090 T DK 96935090T DK 96935090 T DK96935090 T DK 96935090T DK 0863797 T3 DK0863797 T3 DK 0863797T3
Authority
DK
Denmark
Prior art keywords
preparation
coded particles
connection library
sequence tracing
combinatorial connection
Prior art date
Application number
DK96935090T
Other languages
English (en)
Inventor
Paul Henry Kaye
Mark Christopher Tracey
Original Assignee
Univ Hertfordshire
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10782942&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0863797(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Hertfordshire filed Critical Univ Hertfordshire
Application granted granted Critical
Publication of DK0863797T3 publication Critical patent/DK0863797T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00502—Particles of irregular geometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547—Bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547—Bar codes
    • B01J2219/00549—2-dimensional
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B01J2219/00556—Perforations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B01J2219/00558—Cuts-out
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B01J2219/0056—Raised or sunken areas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00592—Split-and-pool, mix-and-divide processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Powder Metallurgy (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK96935090T 1995-10-26 1996-10-25 Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek DK0863797T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9521943.2A GB9521943D0 (en) 1995-10-26 1995-10-26 Coded particles for process sequence tracking in combinatorial compound library preparation
PCT/GB1996/002617 WO1997015390A1 (en) 1995-10-26 1996-10-25 Coded particles for process sequence tracking in combinatorial compound library preparation

Publications (1)

Publication Number Publication Date
DK0863797T3 true DK0863797T3 (da) 2002-04-15

Family

ID=10782942

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96935090T DK0863797T3 (da) 1995-10-26 1996-10-25 Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek

Country Status (11)

Country Link
EP (2) EP0863797B1 (da)
JP (1) JP2000516195A (da)
AT (1) ATE210496T1 (da)
AU (1) AU696505B2 (da)
CA (1) CA2235837A1 (da)
DE (1) DE69618001T2 (da)
DK (1) DK0863797T3 (da)
ES (1) ES2170276T3 (da)
GB (2) GB9521943D0 (da)
PT (1) PT863797E (da)
WO (1) WO1997015390A1 (da)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
US5741462A (en) 1995-04-25 1998-04-21 Irori Remotely programmable matrices with memories
US6025129A (en) 1995-04-25 2000-02-15 Irori Remotely programmable matrices with memories and uses thereof
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6352854B1 (en) 1995-04-25 2002-03-05 Discovery Partners International, Inc. Remotely programmable matrices with memories
CN1181720A (zh) 1995-04-25 1998-05-13 伊萝莉公司 可远程编程的存储器材料及其应用
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US6319668B1 (en) 1995-04-25 2001-11-20 Discovery Partners International Method for tagging and screening molecules
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6340588B1 (en) 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
GB2326152B (en) * 1996-03-07 2000-06-28 Imperial College A composite for combinatorial organic synthesis
GB9707742D0 (en) * 1997-04-17 1997-06-04 Zeneca Ltd Methods
GB2337269B (en) * 1997-04-17 2002-10-09 Zeneca Ltd Method for the preparation of a chemical library
GB9707741D0 (en) * 1997-04-17 1997-06-04 Zeneca Ltd Process
US6096496A (en) * 1997-06-19 2000-08-01 Frankel; Robert D. Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
AU8376998A (en) * 1997-07-24 1999-02-16 Argonaut Technologies, Inc. Compositions for the storage and delivery of solid phase reactive particles and methods of using the same
US6960457B1 (en) * 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
GB2334347B (en) * 1998-02-13 2001-02-28 Univ Hertfordshire An improved method of fabricating coded particles
WO1999041006A1 (en) * 1998-02-13 1999-08-19 University Of Hertfordshire An improved method of fabricating coded particles
GB9814259D0 (en) * 1998-07-02 1998-09-02 Univ Hertfordshire Improvements to the fabrication and method of use of coded particles in the field of combinatorial chemistry
EP1062034A1 (en) * 1998-03-13 2000-12-27 Central Research Laboratories Limited Apparatus for, and method of, manufacturing a plurality of uniquely labelled articles
GB9808783D0 (en) * 1998-04-25 1998-06-24 Central Research Lab Ltd Labelling of small articles
US7060431B2 (en) 1998-06-24 2006-06-13 Illumina, Inc. Method of making and decoding of array sensors with microspheres
GB9820163D0 (en) * 1998-09-17 1998-11-11 Sentec Ltd Micro-fabricated coded labels, reading systems and their applications
WO2000061281A1 (en) * 1999-04-09 2000-10-19 Glaxo Group Limited Encoding scheme for solid phase chemical libraries
US6908737B2 (en) 1999-04-15 2005-06-21 Vitra Bioscience, Inc. Systems and methods of conducting multiplexed experiments
US7253435B2 (en) 1999-04-15 2007-08-07 Millipore Corporation Particles with light-polarizing codes
AU4245900A (en) * 1999-04-15 2000-11-02 Virtual Arrays, Inc. Combinatorial chemical library supports having indicia at coding positions and methods of use
AU771517B2 (en) 1999-04-16 2004-03-25 Mycartis Nv Encoding of microcarriers
US6919009B2 (en) 1999-10-01 2005-07-19 Nanoplex Technologies, Inc. Method of manufacture of colloidal rod particles as nanobarcodes
US7045049B1 (en) 1999-10-01 2006-05-16 Nanoplex Technologies, Inc. Method of manufacture of colloidal rod particles as nanobar codes
US7225082B1 (en) 1999-10-01 2007-05-29 Oxonica, Inc. Colloidal rod particles as nanobar codes
RU2002130821A (ru) * 2000-04-19 2004-04-10 3Д Молекьюлар Сайенсиз Лимитед (Gb) Способ изготовления кодированных частиц
JP2004537712A (ja) 2000-10-18 2004-12-16 バーチャル・アレイズ・インコーポレーテッド 多重細胞分析システム
US7015047B2 (en) 2001-01-26 2006-03-21 Aviva Biosciences Corporation Microdevices having a preferential axis of magnetization and uses thereof
US7811768B2 (en) 2001-01-26 2010-10-12 Aviva Biosciences Corporation Microdevice containing photorecognizable coding patterns and methods of using and producing the same
US7572642B2 (en) 2001-04-18 2009-08-11 Ambrigen, Llc Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns
GB0109545D0 (en) * 2001-04-18 2001-06-06 Scient Generics Ltd Chemical libraries based on coded particles
GB0109746D0 (en) * 2001-04-18 2001-06-13 Scient Generics Ltd Chemical libraries based on coded particles
GB0111470D0 (en) * 2001-05-10 2001-07-04 Scient Generics Ltd Homogenous photoresist functionalisation
WO2003038558A2 (en) * 2001-10-30 2003-05-08 Nanomics Biosystems Pty, Ltd. Device and methods for directed synthesis of chemical libraries
WO2004001375A2 (en) * 2002-06-21 2003-12-31 Burntside Partners Inc Multi-functional product markers and methods for making and using the same
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7619819B2 (en) 2002-08-20 2009-11-17 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7441703B2 (en) 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US20040058457A1 (en) * 2002-08-29 2004-03-25 Xueying Huang Functionalized nanoparticles
AU2003270726A1 (en) 2002-09-12 2004-04-30 Cidra Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
EP1575707A1 (en) 2002-09-12 2005-09-21 Cyvera Corporation Method and apparatus for aligning elongated microbeads in order to interrogate the same
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
JP4520857B2 (ja) * 2002-09-20 2010-08-11 インテル・コーポレーション 走査型プローブ顕微鏡検査（ｓｐｍ）読取用の特定の情報をエンコードするナノバーコードの制御された整列
US7361821B2 (en) 2002-09-20 2008-04-22 Intel Corporation Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading
EP1545762A2 (en) 2002-09-27 2005-06-29 Carlsberg A/S Spatially encoded polymer matrix
GB2393784B (en) * 2002-10-03 2005-06-15 Toshiba Res Europ Ltd An identification tag and method of making an identification tag
GB2393785B (en) 2002-10-03 2005-08-31 Toshiba Res Europ Ltd Method of making a free standing structure
US8081792B2 (en) 2003-08-20 2011-12-20 Illumina, Inc. Fourier scattering methods for encoding microbeads and methods and apparatus for reading the same
US7312257B2 (en) 2003-01-23 2007-12-25 General Electric Company Polymer encapsulation of high aspect ratio materials and methods of making same
GB2405013B (en) * 2003-08-11 2006-02-15 Toshiba Res Europ Ltd A security marker and security marking method
US7488451B2 (en) 2003-09-15 2009-02-10 Millipore Corporation Systems for particle manipulation
US20090210165A1 (en) 2003-12-22 2009-08-20 Carlsberg A/S Identification of encoded beads
US7869011B2 (en) 2003-12-22 2011-01-11 Novo Norkisk A/S Apparatus and methods for analysis and sorting of particles such as polymer beads
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US20050277710A1 (en) * 2004-06-14 2005-12-15 Joyce Richard P Tagged resin, method of making a tagged resin, and articles made therefrom
US7602952B2 (en) 2004-11-16 2009-10-13 Illumina, Inc. Scanner having spatial light modulator
US7604173B2 (en) 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
GB2422686A (en) * 2004-12-07 2006-08-02 Univ Southampton Preparation of solid support particles for chemical reactions
WO2006061600A1 (en) * 2004-12-07 2006-06-15 University Of Southampton Particles for use as a solid support and process for their preparation
WO2007081410A2 (en) 2005-09-13 2007-07-19 True Materials Incorporated Encoded microparticles
US8178278B2 (en) 2005-09-13 2012-05-15 Affymetrix, Inc. Miniaturized microparticles
US7623624B2 (en) 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
EP1976626A2 (en) 2006-01-11 2008-10-08 Novo Nordisk A/S Improved spherical encoded beads
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
JP4803125B2 (ja) * 2007-05-10 2011-10-26 ソニー株式会社 ビーズ群と該ビーズ群の作製方法、並びにビーズ群を用いる方法
EP1995329B1 (en) 2007-05-10 2013-09-25 Sony Corporation Method for sequencing nucleic acids
JP4973993B2 (ja) * 2007-07-23 2012-07-11 財団法人生産技術研究奨励会 マイクロビーズの配列装置における解放装置及びその解放装置の設定方法
GB0725306D0 (en) * 2007-12-28 2008-02-06 Pronostics Ltd Improved microparticles
JP2009174954A (ja) * 2008-01-23 2009-08-06 Fujitsu Ltd コード化粒子
JP4582224B2 (ja) 2008-05-02 2010-11-17 ソニー株式会社 マイクロビーズ作製方法及びマイクロビーズ
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
EP2312393A1 (en) * 2009-10-14 2011-04-20 Biocartis SA Method for producing microparticles
GB2503604B (en) 2011-03-21 2020-04-22 Biodesy Llc Classification of kinase inhibitors using second harmonic optical techniques
EP2825549B1 (en) 2012-03-16 2018-10-10 F. Hoffmann-La Roche SA Engineered conformationally-stabilized proteins
US9139863B2 (en) 2012-03-16 2015-09-22 Genentech, Inc. Engineered conformationally-stabilized proteins
GB2517857A (en) 2012-04-25 2015-03-04 Biodesy Inc Methods for detecting allosteric modulators of proteins
US10436778B2 (en) 2013-03-15 2019-10-08 Plexbio Co., Ltd. Methods and systems for multiplex assays
MX2016014504A (es) 2014-05-05 2017-05-23 Regeneron Pharma Animales c5 y c3 humanizados.
EP3237906B8 (en) 2014-12-23 2020-10-28 Bluelight Therapeutics, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
TWI737614B (zh) 2015-06-11 2021-09-01 博錸生技股份有限公司 已編碼微載體及其製造方法以及用以進行多工分析之包含該等已編碼微載體之套件
CA3048202A1 (en) 2015-12-23 2017-06-29 Moonshot Pharma Llc Methods for inducing an immune response by inhibition of nonsense mediated decay
WO2018052464A1 (en) 2016-09-16 2018-03-22 Plexbio Co., Ltd. Methods and systems for multiplex assays
WO2018157027A1 (en) 2017-02-27 2018-08-30 Regeneron Pharmaceuticals, Inc. Humanized model of kidney and liver disorders
JP2020525434A (ja) 2017-06-22 2020-08-27 ムーンショット ファーマ エルエルシー アンレキサノクス及び免疫調節剤を含む組成物で癌を治療する方法
WO2020150910A1 (zh) * 2019-01-23 2020-07-30 深圳华大生命科学研究院 微珠

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053433A (en) * 1975-02-19 1977-10-11 Minnesota Mining And Manufacturing Company Method of tagging with color-coded microparticles
CA1056653A (en) * 1975-11-10 1979-06-19 Edward J. Stevens Color-coded identifier microparticles
US4390452A (en) * 1979-08-20 1983-06-28 Minnesota Mining & Manufacturing Company Microparticles with visual identifying means
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4767205A (en) * 1986-01-28 1988-08-30 Flow Cytometry Standards Corporation Composition and method for hidden identification
EP0604552B1 (en) * 1991-09-18 1997-02-12 Affymax Technologies N.V. Method of synthesizing diverse collections of oligomers
NZ257077A (en) * 1992-11-06 1997-05-26 Chiron Mimotopes Pty Ltd Support for synthesis of modular polymers
US5429392A (en) * 1993-06-18 1995-07-04 Loving; Charles D. Composite microdot and method
GB2318666B (en) * 1994-04-25 1998-07-15 Univ Hertfordshire Coded items for labelling objects

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GB2306484A (en) 1997-05-07
DE69618001T2 (de) 2002-08-14
EP1018365A2 (en) 2000-07-12
GB2306484B (en) 1997-09-24
AU7318496A (en) 1997-05-15
EP1018365A3 (en) 2000-10-11
CA2235837A1 (en) 1997-05-01
AU696505B2 (en) 1998-09-10
EP0863797A1 (en) 1998-09-16
EP1018365A8 (en) 2001-03-28
JP2000516195A (ja) 2000-12-05
DE69618001D1 (de) 2002-01-24
GB9622249D0 (en) 1996-12-18
EP1018365A9 (en) 2001-05-16
GB9521943D0 (en) 1996-01-03
PT863797E (pt) 2002-05-31
ES2170276T3 (es) 2002-08-01
WO1997015390A1 (en) 1997-05-01
ATE210496T1 (de) 2001-12-15
EP0863797B1 (en) 2001-12-12

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