DK0880496T3 - Biphenylforbindelser, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf - Google Patents

Biphenylforbindelser, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf

Info

Publication number
DK0880496T3
DK0880496T3 DK97902408T DK97902408T DK0880496T3 DK 0880496 T3 DK0880496 T3 DK 0880496T3 DK 97902408 T DK97902408 T DK 97902408T DK 97902408 T DK97902408 T DK 97902408T DK 0880496 T3 DK0880496 T3 DK 0880496T3
Authority
DK
Denmark
Prior art keywords
drugs
pct
processes
preparation
pharmaceutical preparations
Prior art date
Application number
DK97902408T
Other languages
Danish (da)
English (en)
Inventor
Dominique Lesuisse
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK0880496T3 publication Critical patent/DK0880496T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/38—Halogenated derivatives with at least one hydroxy group on a condensed ring system containing two rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK97902408T 1996-02-01 1997-01-30 Biphenylforbindelser, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf DK0880496T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9601212A FR2744444B1 (fr) 1996-02-01 1996-02-01 Nouveaux composes biphenyles, procede et intermediaires de preparation, application a titre de medicaments et compositions pharmaceutiques les renfermant
PCT/FR1997/000184 WO1997028116A1 (fr) 1996-02-01 1997-01-30 Composes biphenyles et leur utilisation comme agents estrogeniques

Publications (1)

Publication Number Publication Date
DK0880496T3 true DK0880496T3 (da) 2002-09-09

Family

ID=9488725

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97902408T DK0880496T3 (da) 1996-02-01 1997-01-30 Biphenylforbindelser, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf

Country Status (10)

Country Link
US (2) US6147119A (de)
EP (1) EP0880496B1 (de)
JP (1) JP4143122B2 (de)
AT (1) ATE218122T1 (de)
DE (1) DE69712868T2 (de)
DK (1) DK0880496T3 (de)
ES (1) ES2175337T3 (de)
FR (1) FR2744444B1 (de)
PT (1) PT880496E (de)
WO (1) WO1997028116A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6914074B2 (en) * 2001-12-13 2005-07-05 Wyeth Substituted phenyl naphthalenes as estrogenic agents
EP1835895A2 (de) * 2004-12-31 2007-09-26 Aventis Pharmaceuticals Inc. Verwendung bestimmter phenyl-naphthyl-verbindungen ohne besondere affinität zu er-alpha oder beta zum schutz von neuronen und oligodendrozyten bei der behandlung von multipler sklerose
BRPI0519303A2 (pt) * 2004-12-31 2009-01-06 Aventis Pharma Inc uso de compostos selecionados para proteÇço de neurânios e oligodendràcitos no tratamento de esclerose méltipla
RU2007129852A (ru) * 2005-01-04 2009-02-20 Авентис Фармасьютикалз Инк. (Us) Применение фенилнафтильных соединений для защиты нейронов и олигодендроцитов при лечении рассеянного склероза (рс)
JP4590637B2 (ja) * 2006-02-16 2010-12-01 国立大学法人 千葉大学 ベンゼン誘導体の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0532579A (ja) * 1991-08-01 1993-02-09 Banyu Pharmaceut Co Ltd エストロゲン物質ｂｅ−２５３２７及びその製造法

Also Published As

Publication number Publication date
JP4143122B2 (ja) 2008-09-03
US6147119A (en) 2000-11-14
ES2175337T3 (es) 2002-11-16
JP2000504003A (ja) 2000-04-04
EP0880496B1 (de) 2002-05-29
US6365775B1 (en) 2002-04-02
WO1997028116A1 (fr) 1997-08-07
DE69712868D1 (de) 2002-07-04
DE69712868T2 (de) 2002-11-28
FR2744444A1 (fr) 1997-08-08
ATE218122T1 (de) 2002-06-15
EP0880496A1 (de) 1998-12-02
PT880496E (pt) 2002-10-31
FR2744444B1 (fr) 1998-05-29

Similar Documents

Publication Publication Date Title
DK0871606T3 (da) Nye forbindelser og deres præparat med anti-inflammatorisk og anti-thrombotisk aktivitet
BR9713126B1 (pt) compostos derivados da piridin-2-il-metilamina, processo para sua preparaÇço, compostos intermediÁrios de sÍntese, uso de um composto, e, composiÇço farmacÊutica.
NO306346B1 (no) N-substituerte azabicykloalkanderivater, anvendelse derav og farmasöytisk preparat
DK0733046T3 (da) Benzoylguanidiner, deres fremstilling og anvendelse i medikamenter
DK0506539T3 (da) heterocykliske alkylamider, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
DK0506778T3 (da) Substituerede 4-phenyl-4-piperidincarboxamider med både lokal anæstetisk og analgetisk virkning samt fremgangsmåder til deres fremstilling
DE69313051D1 (de) Ethanolamin-derivate mit sympathomimetischer und anti-pollakiuria wirkung
MY118828A (en) Substituted amino compounds and their use as substances having an analgesic effect
PT839041E (pt) Sais de derivados de amidina e de inibidor de ciclooxigenase processo para a sua preparacao sua utilizacao como farmacos e composicoes farmaceuticas contendo os referidos sais
ATE199013T1 (de) N-(4-substituerte benzyl)-2-aminolactamderivate
DK0891341T3 (da) 1,3,4-Oxadiazinderivater samt deres anvendelse som pesticider
NO982708L (no) Nye fenylamidinderivater, fremgangsmÕte for fremstilling derav og deres anvendelse som legemidler
DK0880496T3 (da) Biphenylforbindelser, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf
BR9814495A (pt) Composto, processo para prepará-lo, uso do mesmo, composição farmacêutica, e, processo
NO995685D0 (no) Nye glycosylerte ginkgolidderivater, anvendelse derav som medikamenter og farmasöytiske blandinger
DK0634396T3 (da) Aminosyrederivater og deres anvendelse som enkeltfalinaseinhibitorer
NO970435D0 (no) Nye, 3-substituerte 3H-2,3-benzodiazepinderivater, fremstilling av dem og anvendelse av dem som legemidler
ATE173471T1 (de) Pyridazinonderivate oder deren salze, verfahren zu ihrer herstellung und diese enthaltende antischockmittel
BR9610175A (pt) Composto processo de preparação do composto composição farmacêutica e utilização do composto
DK1000067T3 (da) Thiazolobenzoheterocycliske forbindelser, deres fremstilling og lægemidler indeholdende forbindelserne
BR9807785A (pt) Processo para a preparação do composto, e, composto
DK0989994T3 (da) Streptograminderivater, deres fremstilling og præparater, der indeholder dem
ES2163001T3 (es) Nuevos derivados de borneol, procedimiento para su preparacion y su utilizacion farmaceutica.
ES2065855B1 (es) Procedimiento para la preparacion de nuevos derivados desoxiazafosfolipidicos con accion inhibidora de la fosfolipasa a2, nuevos derivados desoxiazafosfolipidicos obtenidos y utilizacion de los mismos.
NO954316D0 (no) Benzo(f)kinoksalidinonderivater, deres fremstilling og anvendelse i legemidler