DK0881229T3 - Alkylerede antibiotiske hexapeptider - Google Patents

Alkylerede antibiotiske hexapeptider

Info

Publication number
DK0881229T3
DK0881229T3 DK98303488T DK98303488T DK0881229T3 DK 0881229 T3 DK0881229 T3 DK 0881229T3 DK 98303488 T DK98303488 T DK 98303488T DK 98303488 T DK98303488 T DK 98303488T DK 0881229 T3 DK0881229 T3 DK 0881229T3
Authority
DK
Denmark
Prior art keywords
alkylated
hexapeptides
antibiotic
derivatives
desleucyl
Prior art date
Application number
DK98303488T
Other languages
English (en)
Inventor
Richard Craig Thompson
Stephen Charles Wilkie
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0881229T3 publication Critical patent/DK0881229T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK98303488T 1997-05-20 1998-05-05 Alkylerede antibiotiske hexapeptider DK0881229T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4719797P 1997-05-20 1997-05-20

Publications (1)

Publication Number Publication Date
DK0881229T3 true DK0881229T3 (da) 2003-11-03

Family

ID=21947599

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98303488T DK0881229T3 (da) 1997-05-20 1998-05-05 Alkylerede antibiotiske hexapeptider

Country Status (11)

Country Link
US (1) US5977063A (da)
EP (1) EP0881229B1 (da)
JP (1) JP4240544B2 (da)
AT (1) ATE244728T1 (da)
AU (1) AU7280698A (da)
CA (1) CA2290705A1 (da)
DE (1) DE69816180T2 (da)
DK (1) DK0881229T3 (da)
ES (1) ES2202746T3 (da)
PT (1) PT881229E (da)
WO (1) WO1998052589A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
US6518242B1 (en) 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
CA2318394A1 (en) * 1998-02-20 1999-08-26 Advanced Medicine, Inc. Novel antibacterial agents
CA2337103A1 (en) 1998-07-14 2000-01-27 Robert Kerns Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
US6710168B1 (en) 1999-05-19 2004-03-23 The Trustees Of The University Of Princeton Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
PT1140993E (pt) * 1998-12-23 2003-10-31 Theravance Inc Derivados de glicopeptidos e composicoes farmaceuticas contendo os mesmos
US6699836B2 (en) 1999-04-02 2004-03-02 The Trustees Of Princeton University Vancomycin analogs
US6518243B1 (en) 1999-04-02 2003-02-11 Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
WO2000069893A1 (en) 1999-05-19 2000-11-23 Merck & Co., Inc. Glycopeptide antibacterial compounds, compositions containing same and methods of using same
US8778874B2 (en) 2004-11-29 2014-07-15 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
JP5178520B2 (ja) 2005-09-22 2013-04-10 メディバス エルエルシー 固体ポリマー送達組成物およびその使用法
US20090176674A1 (en) * 2006-01-09 2009-07-09 The Procter & Gamble Company Personal care compositions containing cationic synthetic copolymer and a detersive surfactant
CN101959900A (zh) 2007-12-26 2011-01-26 盐野义制药株式会社 糖肽类抗生素糖基化衍生物
EP2260060A4 (en) 2008-04-01 2013-01-16 Univ Cornell ORGANIC SOLUBLE CHITOSA SALT AND CHITOSAN DERIVED BIOMATERIALS MANUFACTURED THEREFROM

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5534420A (en) * 1988-07-28 1996-07-09 Eli Lilly And Company Biotransformation of glycopeptide antibiotics
ZA909847B (en) * 1989-12-13 1992-08-26 Lilly Co Eli Glycopeptide derivatives
US5721208A (en) * 1991-06-29 1998-02-24 Hoechst Aktiengesellschaft Glycopeptides a process for their preparation and their use
TW213468B (da) * 1991-06-29 1993-09-21 Hoechst Ag
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
TW457248B (en) * 1994-01-28 2001-10-01 Lilly Co Eli Glycopeptide antibiotic derivatives
AU2441697A (en) * 1996-04-12 1997-11-07 Eli Lilly And Company Covalently-linked glycopeptide dimers

Also Published As

Publication number Publication date
ES2202746T3 (es) 2004-04-01
EP0881229A2 (en) 1998-12-02
JP2001525852A (ja) 2001-12-11
DE69816180D1 (de) 2003-08-14
DE69816180T2 (de) 2004-04-22
AU7280698A (en) 1998-12-11
WO1998052589A1 (en) 1998-11-26
CA2290705A1 (en) 1998-11-26
ATE244728T1 (de) 2003-07-15
JP4240544B2 (ja) 2009-03-18
EP0881229B1 (en) 2003-07-09
US5977063A (en) 1999-11-02
EP0881229A3 (en) 1998-12-23
PT881229E (pt) 2003-11-28

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