DK0888337T3 - Piperidon-tachykininantagonister - Google Patents
Piperidon-tachykininantagonisterInfo
- Publication number
- DK0888337T3 DK0888337T3 DK97901034T DK97901034T DK0888337T3 DK 0888337 T3 DK0888337 T3 DK 0888337T3 DK 97901034 T DK97901034 T DK 97901034T DK 97901034 T DK97901034 T DK 97901034T DK 0888337 T3 DK0888337 T3 DK 0888337T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- tachykinin antagonists
- piperidone
- preparation
- cycloalkyl
- Prior art date
Links
- 102000003141 Tachykinin Human genes 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- 108060008037 tachykinin Proteins 0.000 title abstract 2
- XUWHAWMETYGRKB-UHFFFAOYSA-N piperidin-2-one Chemical compound O=C1CCCCN1 XUWHAWMETYGRKB-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9601202.6A GB9601202D0 (en) | 1996-01-22 | 1996-01-22 | Piperidones |
| PCT/EP1997/000162 WO1997027185A1 (en) | 1996-01-22 | 1997-01-09 | Piperidone tachykinin antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0888337T3 true DK0888337T3 (da) | 2002-07-01 |
Family
ID=10787341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97901034T DK0888337T3 (da) | 1996-01-22 | 1997-01-09 | Piperidon-tachykininantagonister |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6262075B1 (de) |
| EP (1) | EP0888337B1 (de) |
| JP (1) | JP3140063B2 (de) |
| AT (1) | ATE218563T1 (de) |
| AU (1) | AU1442297A (de) |
| CA (1) | CA2240964C (de) |
| CO (1) | CO4560412A1 (de) |
| DE (1) | DE69713075T2 (de) |
| DK (1) | DK0888337T3 (de) |
| ES (1) | ES2175328T3 (de) |
| GB (1) | GB9601202D0 (de) |
| HR (1) | HRP970040A2 (de) |
| MA (1) | MA26418A1 (de) |
| PT (1) | PT888337E (de) |
| TN (1) | TNSN97014A1 (de) |
| WO (1) | WO1997027185A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9600235D0 (en) * | 1996-01-05 | 1996-03-06 | Pfizer Ltd | Therapeutic agents |
| AU1089599A (en) * | 1997-10-15 | 1999-05-03 | Coelacanth Chemical Corporation | Synthesis of azetidine derivatives |
| KR100610538B1 (ko) * | 1997-12-04 | 2006-08-09 | 상꾜 가부시키가이샤 | 지환식 아실화 복소환 유도체 |
| GB9812037D0 (en) * | 1998-06-04 | 1998-07-29 | Pfizer Ltd | Piperidones |
| GB9924141D0 (en) * | 1998-10-30 | 1999-12-15 | Zeneca Ltd | Treatment of gastric asthma |
| GB0005366D0 (en) * | 2000-03-06 | 2000-04-26 | Xenova Ltd | Pharmaceutical compounds |
| TW200508221A (en) | 2003-06-13 | 2005-03-01 | Astrazeneca Ab | New azetidine compounds |
| US20040265238A1 (en) | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
| DE10336274A1 (de) * | 2003-08-07 | 2005-03-10 | Honeywell Specialty Chemicals | Verfahren zur Herstellung von geminalen Difluoralkanen |
| CN101208327A (zh) * | 2005-06-23 | 2008-06-25 | 阿斯利康(瑞典)有限公司 | 作为神经激肽受体拮抗剂用于治疗胃肠疾病的新氮杂环丁烷衍生物 |
| EP1899326A4 (de) * | 2005-06-23 | 2009-12-16 | Albireo Ab | Neue azetidinderivate als neurokininrezeptorantagonisten zur behandlung von magen-darm-erkrankungen |
| AR056087A1 (es) * | 2005-09-29 | 2007-09-19 | Astrazeneca Ab | Derivados de azetidina como antagonistas de receptores de neuroquina nk |
| AR057828A1 (es) * | 2005-09-29 | 2007-12-19 | Astrazeneca Ab | Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica |
| US8106208B2 (en) | 2006-05-18 | 2012-01-31 | Albireo Ab | Benzamide compounds that act as NK receptor antagonists |
| JP2010516731A (ja) | 2007-01-24 | 2010-05-20 | グラクソ グループ リミテッド | ２−メトキシ−５−（５−トリフルオロメチル−テトラゾール−１−イル）−ベンジル］−（２ｓ−フェニル−ピペリジン−３ｓ−イル）−アミンを含む医薬組成物 |
| TW201026666A (en) * | 2008-12-16 | 2010-07-16 | Astrazeneca Ab | Quaternary piperidine derivatives and uses thereof |
| US8946434B2 (en) | 2010-07-16 | 2015-02-03 | N30 Pharmaceuticals, Inc. | Dihydropyridin-2(1H)-one compound as S-nirtosoglutathione reductase inhibitors and neurokinin-3 receptor antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| TW432061B (en) * | 1994-08-09 | 2001-05-01 | Pfizer Res & Dev | Lactams |
| FR2729951B1 (fr) * | 1995-01-30 | 1997-04-18 | Sanofi Sa | Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant |
-
1996
- 1996-01-22 GB GBGB9601202.6A patent/GB9601202D0/en active Pending
-
1997
- 1997-01-09 WO PCT/EP1997/000162 patent/WO1997027185A1/en not_active Ceased
- 1997-01-09 AT AT97901034T patent/ATE218563T1/de not_active IP Right Cessation
- 1997-01-09 JP JP09526485A patent/JP3140063B2/ja not_active Expired - Fee Related
- 1997-01-09 ES ES97901034T patent/ES2175328T3/es not_active Expired - Lifetime
- 1997-01-09 CA CA002240964A patent/CA2240964C/en not_active Expired - Fee Related
- 1997-01-09 PT PT97901034T patent/PT888337E/pt unknown
- 1997-01-09 EP EP97901034A patent/EP0888337B1/de not_active Expired - Lifetime
- 1997-01-09 AU AU14422/97A patent/AU1442297A/en not_active Abandoned
- 1997-01-09 US US09/117,011 patent/US6262075B1/en not_active Expired - Fee Related
- 1997-01-09 DK DK97901034T patent/DK0888337T3/da active
- 1997-01-09 DE DE69713075T patent/DE69713075T2/de not_active Expired - Fee Related
- 1997-01-17 CO CO97001936A patent/CO4560412A1/es unknown
- 1997-01-21 TN TNTNSN97014A patent/TNSN97014A1/fr unknown
- 1997-01-22 MA MA24472A patent/MA26418A1/fr unknown
- 1997-01-22 HR HR9601202.6A patent/HRP970040A2/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69713075D1 (de) | 2002-07-11 |
| WO1997027185A1 (en) | 1997-07-31 |
| ES2175328T3 (es) | 2002-11-16 |
| JPH11505271A (ja) | 1999-05-18 |
| DE69713075T2 (de) | 2003-02-27 |
| EP0888337B1 (de) | 2002-06-05 |
| TNSN97014A1 (fr) | 2005-03-15 |
| MA26418A1 (fr) | 2004-12-20 |
| CA2240964C (en) | 2002-06-25 |
| AU1442297A (en) | 1997-08-20 |
| CA2240964A1 (en) | 1997-07-31 |
| EP0888337A1 (de) | 1999-01-07 |
| JP3140063B2 (ja) | 2001-03-05 |
| CO4560412A1 (es) | 1998-02-10 |
| ATE218563T1 (de) | 2002-06-15 |
| US6262075B1 (en) | 2001-07-17 |
| GB9601202D0 (en) | 1996-03-20 |
| PT888337E (pt) | 2002-09-30 |
| HRP970040A2 (en) | 1998-06-30 |
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