DK0896629T3 - Fremgangsmåder og præparater til påvisning af splejsningsdefekter i dihydropyrimidindehydro-genasegenet - Google Patents

Fremgangsmåder og præparater til påvisning af splejsningsdefekter i dihydropyrimidindehydro-genasegenet

Info

Publication number
DK0896629T3
DK0896629T3 DK97915143T DK97915143T DK0896629T3 DK 0896629 T3 DK0896629 T3 DK 0896629T3 DK 97915143 T DK97915143 T DK 97915143T DK 97915143 T DK97915143 T DK 97915143T DK 0896629 T3 DK0896629 T3 DK 0896629T3
Authority
DK
Denmark
Prior art keywords
methods
dihydropyrimidine dehydrogenase
compositions
dehydrogenase gene
splicing defects
Prior art date
Application number
DK97915143T
Other languages
English (en)
Inventor
Frank J Gonzalez
Pedro Fernandez-Salguero
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of DK0896629T3 publication Critical patent/DK0896629T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK97915143T 1996-03-20 1997-03-19 Fremgangsmåder og præparater til påvisning af splejsningsdefekter i dihydropyrimidindehydro-genasegenet DK0896629T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1383596P 1996-03-20 1996-03-20
PCT/US1997/004269 WO1997035034A1 (en) 1996-03-20 1997-03-19 Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations

Publications (1)

Publication Number Publication Date
DK0896629T3 true DK0896629T3 (da) 2003-02-03

Family

ID=21762020

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97915143T DK0896629T3 (da) 1996-03-20 1997-03-19 Fremgangsmåder og præparater til påvisning af splejsningsdefekter i dihydropyrimidindehydro-genasegenet

Country Status (8)

Country Link
EP (1) EP0896629B8 (da)
AT (1) ATE225404T1 (da)
AU (1) AU2215897A (da)
CA (1) CA2249364C (da)
DE (1) DE69716057T2 (da)
DK (1) DK0896629T3 (da)
ES (1) ES2185002T3 (da)
WO (1) WO1997035034A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787306B1 (en) 1996-03-20 2004-09-07 The United States Of America As Represented By The Department Of Health And Human Services Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations
AU771446B2 (en) * 1996-03-20 2004-03-25 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations
WO2001036686A2 (en) * 1999-11-15 2001-05-25 University Of Southern California Genomic polymorphism for predicting therapeutic response
US6602670B2 (en) 2000-12-01 2003-08-05 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 expression
US7049059B2 (en) 2000-12-01 2006-05-23 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression
US7005278B2 (en) 2001-03-02 2006-02-28 Danenberg Kathleen D Method of determining dihydropyrimidine dehydrogenase gene expression
US20020142328A1 (en) 2000-12-01 2002-10-03 Danenberg Kathleen D. Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors
US6956111B2 (en) 2001-03-02 2005-10-18 Response Genetics, Inc. Method of determining dihydropyrimidine dehydrogenase gene expression
US6686155B2 (en) 2001-06-14 2004-02-03 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression
FR2884257B1 (fr) * 2005-04-12 2010-11-26 Centre Regional De Lutte Contre Le Cancer Dangers Prevention des toxicites dues au 5-fluorouracile
JP4880621B2 (ja) * 2006-01-25 2012-02-22 大鵬薬品工業株式会社 ５−フルオロウラシル系抗癌剤に対する感受性を予測する方法

Also Published As

Publication number Publication date
ES2185002T3 (es) 2003-04-16
ATE225404T1 (de) 2002-10-15
AU2215897A (en) 1997-10-10
DE69716057D1 (de) 2002-11-07
DE69716057T2 (de) 2003-07-03
EP0896629B1 (en) 2002-10-02
EP0896629A1 (en) 1999-02-17
EP0896629B8 (en) 2003-01-02
WO1997035034A1 (en) 1997-09-25
CA2249364A1 (en) 1997-09-25
CA2249364C (en) 2009-07-07

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