DK0904061T3 - Farmaceutisk sammensætning på basis af rhein eller diacerhein med forbedret biotilgængelighed - Google Patents

Farmaceutisk sammensætning på basis af rhein eller diacerhein med forbedret biotilgængelighed

Info

Publication number
DK0904061T3
DK0904061T3 DK97952996T DK97952996T DK0904061T3 DK 0904061 T3 DK0904061 T3 DK 0904061T3 DK 97952996 T DK97952996 T DK 97952996T DK 97952996 T DK97952996 T DK 97952996T DK 0904061 T3 DK0904061 T3 DK 0904061T3
Authority
DK
Denmark
Prior art keywords
diacerhein
rhein
pct
pharmaceutical composition
improved bioavailability
Prior art date
Application number
DK97952996T
Other languages
English (en)
Inventor
Cyril Estanove
Alain Prudhomme
Original Assignee
Mazal Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mazal Pharma filed Critical Mazal Pharma
Application granted granted Critical
Publication of DK0904061T3 publication Critical patent/DK0904061T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK97952996T 1996-12-23 1997-12-23 Farmaceutisk sammensætning på basis af rhein eller diacerhein med forbedret biotilgængelighed DK0904061T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9615867A FR2757397B1 (fr) 1996-12-23 1996-12-23 Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree
PCT/FR1997/002403 WO1998027965A1 (fr) 1996-12-23 1997-12-23 Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree

Publications (1)

Publication Number Publication Date
DK0904061T3 true DK0904061T3 (da) 2003-01-27

Family

ID=9499012

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97952996T DK0904061T3 (da) 1996-12-23 1997-12-23 Farmaceutisk sammensætning på basis af rhein eller diacerhein med forbedret biotilgængelighed

Country Status (14)

Country Link
US (1) US6124358A (da)
EP (1) EP0904061B1 (da)
JP (1) JP4166834B2 (da)
CN (1) CN1128612C (da)
AT (1) ATE225649T1 (da)
BR (1) BR9707581A (da)
CA (1) CA2247520C (da)
DE (1) DE69716261T2 (da)
DK (1) DK0904061T3 (da)
ES (1) ES2184148T3 (da)
FR (1) FR2757397B1 (da)
IL (1) IL125794A (da)
PT (1) PT904061E (da)
WO (1) WO1998027965A1 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2270306C (en) * 1999-04-27 2000-09-26 Bernard Charles Sherman Pharmaceutical compositions comprising co-micronized fenofibrate
AR026801A1 (es) * 2000-01-12 2003-02-26 Medidom Lab Sustancias para uso en el tratamiento de la psoriasis
AU2002214306A1 (en) * 2000-11-17 2002-05-27 Takeda Chemical Industries Ltd. Pharmaceutical preparation containing talc/barium sulfate
US20020128317A1 (en) * 2001-01-23 2002-09-12 Laboratories Negma Treatment of pathological conditions characterized by an increased IL-1 level
FR2821555B1 (fr) * 2001-03-01 2003-05-16 Besins Int Lab Progestatif co-micronise avec un tensioactif, composition pharmaceutique le comprenant, leurs procedes de fabrication et leurs utilisations
US6797727B2 (en) * 2001-07-16 2004-09-28 Transition Therapeutics Inc. Use of rhein or diacerhein compounds for the treatment or prevention of vascular diseases
GB0404953D0 (en) * 2004-03-04 2004-04-07 Arakis Ltd Pro-drugs
WO2006119166A2 (en) 2005-04-29 2006-11-09 The Regents Of The University Of Colorado Multi-excitation diagnostic systems and methods for classification of tissue
FR2920991A1 (fr) * 2007-09-14 2009-03-20 Wockhardt Ltd Composition a base de diacerheine pour le traitement de l'arthrose
EP2471516A3 (en) 2007-09-14 2012-12-26 Wockhardt Limited Rhein or diacerein compositions
CA2926610A1 (en) * 2007-09-27 2009-04-02 Wockhardt Research Centre Pharmaceutical compositions of rhein or diacerein
ES2382026T3 (es) * 2007-09-27 2012-06-04 Wockhardt Limited Composiciones farmacéuticas autoemulsionantes de reína o diacereína
US20100285114A1 (en) * 2007-09-27 2010-11-11 Rahul Dabre Pharmaceutical compositions of rhein or diacerein
AU2013200971B2 (en) * 2007-09-27 2014-05-08 Wockhardt Limited Pharmaceutical compositions of rhein or diacerein
WO2009048940A2 (en) * 2007-10-08 2009-04-16 Dr. Reddy's Laboratories Ltd. Diacerein pharmaceutical formulations
EP2060562A1 (en) * 2007-11-16 2009-05-20 Laboratoire Medidom S.A. Dioxoanthracene sulphonate derivatives
EP2280697A1 (en) * 2008-04-30 2011-02-09 Wockhardt Research Centre Oral liquid compositions of rhein or diacerein
TWI473610B (zh) * 2008-10-28 2015-02-21 Twi Biotechnology Inc 包含雙醋瑞因（ｄｉａｃｅｒｅｉｎ）之醫藥組合物
JP2013502587A (ja) * 2009-08-20 2013-01-24 ティダブリューアイ・バイオテクノロジー・インコーポレイテッド 糖尿病の診断および治療効果の決定方法
CN101822660B (zh) * 2010-05-13 2013-07-10 中国人民解放军肾脏病研究所 大黄酸类化合物或其盐在制备预防和治疗胰岛β细胞功能衰退药物中的应用
US20140377343A1 (en) 2011-12-23 2014-12-25 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Formulations of flurbiprofen and diacerein
WO2013177061A1 (en) 2012-05-21 2013-11-28 The Regents Of The University Of Colorado, A Body Corporate Three-dimensional mapping and therapy of prostate cancer
US9814448B2 (en) 2012-05-21 2017-11-14 Precision Biopsy, Inc. Three-dimensional optical imaging and therapy of prostate cancer
FR2997627B1 (fr) * 2012-11-08 2015-01-16 Hra Pharma Lab Produit de co-micronisation comprenant de l'ulipristal acetate
EP3316879A4 (en) * 2015-07-01 2019-01-23 TWI Biotechnology, Inc. TOPICAL DIACEREIN OR RHEIN FORMULATIONS AND USES THEREOF

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis
US4344934A (en) * 1978-11-20 1982-08-17 American Home Products Corporation Therapeutic compositions with enhanced bioavailability
FR2627696B1 (fr) * 1988-02-26 1991-09-13 Fournier Innovation Synergie Nouvelle forme galenique du fenofibrate
IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione
IT1241417B (it) * 1990-03-06 1994-01-14 Vectorpharma Int Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
US5393898A (en) * 1991-06-25 1995-02-28 Madaus Ag Method of preparing diacetyl rhein
ATE183641T1 (de) * 1992-12-23 1999-09-15 Saitec Srl Verfahren zur herstellung von arzneiformen und kontrollierte freigabe und die soerhaltenen arzneiformen
US5652265A (en) * 1995-03-29 1997-07-29 Wisconsin Alumni Research Foundation Production of rhein and rhein derivatives
IT1276781B1 (it) * 1995-06-23 1997-11-03 Gentili Ist Spa Derivati antrachinonmono- e disolfon- sostituiti e composizioni farmaceutiche che li contengono per il trattamento delle patologie

Also Published As

Publication number Publication date
ES2184148T3 (es) 2003-04-01
IL125794A (en) 2000-12-06
WO1998027965A1 (fr) 1998-07-02
DE69716261D1 (de) 2002-11-14
FR2757397A1 (fr) 1998-06-26
BR9707581A (pt) 1999-07-27
US6124358A (en) 2000-09-26
JP4166834B2 (ja) 2008-10-15
JP2000505817A (ja) 2000-05-16
CN1211917A (zh) 1999-03-24
EP0904061A1 (fr) 1999-03-31
CA2247520C (fr) 2007-03-27
ATE225649T1 (de) 2002-10-15
CA2247520A1 (fr) 1998-07-02
PT904061E (pt) 2003-02-28
EP0904061B1 (fr) 2002-10-09
IL125794A0 (en) 1999-04-11
DE69716261T2 (de) 2003-09-18
CN1128612C (zh) 2003-11-26
FR2757397B1 (fr) 1999-03-05

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