DK0921117T3 - Guanidinforbindelser - Google Patents

Guanidinforbindelser

Info

Publication number: DK0921117T3
Authority: DK; Denmark
Prior art keywords: trifluoromethyl; hydrogen; fluoro; chloro; alkyl
Prior art date: 1993-08-24

Application number

DK99102583T

Other languages

English (en)

Other versions

DK0921117T4 (da

Inventor

Heinz-Werner Dr Kleemann

Hans-Jochen Dr Lang

Andreas Dr Weichert

Wolfgang Dr Scholz

Udo Dr Albus

Jan-Robert Dr Schwark

Peter Dr Crause

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-08-24

Filing date

1994-08-18

Publication date

2004-04-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6495834&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0921117(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1994-08-18 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2004-04-13 Publication of DK0921117T3 publication Critical patent/DK0921117T3/da

2009-05-11 Application granted granted Critical

2009-05-11 Publication of DK0921117T4 publication Critical patent/DK0921117T4/da

Links

ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 2
CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 title 1
SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 title 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 7
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 4
125000001153 fluoro group Chemical group F* 0.000 abstract 4
125000001309 chloro group Chemical group Cl* 0.000 abstract 3
-1 chloro, hydroxy, amino Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical class 0.000 abstract 3
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
AJDQRQQNNLZLPM-UHFFFAOYSA-N n-(diaminomethylidene)benzamide Chemical class NC(N)=NC(=O)C1=CC=CC=C1 AJDQRQQNNLZLPM-UHFFFAOYSA-N 0.000 abstract 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000001246 bromo group Chemical group Br* 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000000168 pyrrolyl group Chemical group 0.000 abstract 1
125000005493 quinolyl group Chemical group 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Saccharide Compounds (AREA)
Pyridine Compounds (AREA)

DK99102583T 1993-08-24 1994-08-18 Guanidinforbindelser DK0921117T4 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4328352A DE4328352A1 (de)	1993-08-24	1993-08-24	Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number	Publication Date
DK0921117T3 true DK0921117T3 (da)	2004-04-13
DK0921117T4 DK0921117T4 (da)	2009-05-11

Family

ID=6495834

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK94112895T DK0640587T3 (da)	1993-08-24	1994-08-18	Diacylsubstituerede guanidiner, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemiddel eller diagnostisk mid
DK99102583T DK0921117T4 (da)	1993-08-24	1994-08-18	Guanidinforbindelser

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK94112895T DK0640587T3 (da)	1993-08-24	1994-08-18	Diacylsubstituerede guanidiner, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemiddel eller diagnostisk mid

Country Status (16)

Country	Link
US (3)	US6436999B1 (da)
EP (2)	EP0921117B2 (da)
JP (2)	JP3790557B2 (da)
AT (2)	ATE188208T1 (da)
AU (3)	AU692776B2 (da)
CA (2)	CA2546602C (da)
DE (3)	DE4328352A1 (da)
DK (2)	DK0640587T3 (da)
ES (2)	ES2210872T5 (da)
FI (1)	FI120390B (da)
GR (1)	GR3032685T3 (da)
HU (1)	HU223055B1 (da)
NO (1)	NO302569B1 (da)
NZ (1)	NZ264282A (da)
PT (2)	PT640587E (da)
TW (1)	TW469265B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19546736A1 (de) *	1995-12-14	1997-06-19	Hoechst Ag	Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate
DE19633966A1 (de) *	1996-08-22	1998-02-26	Hoechst Ag	Phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
JP2002502414A (ja) *	1997-06-02	2002-01-22	藤沢薬品工業株式会社	細胞中のＮａ▲上＋▼／Ｈ▲上＋▼交換の阻害剤としてのグアニジン誘導体
KR20010042618A (ko)	1998-04-24	2001-05-25	후지야마 아키라	구아니딘 유도체
DE19859727A1 (de)	1998-12-23	2000-06-29	Aventis Pharma Gmbh	Die Verwendung von Hemmern des Natrium-Wasserstoff-Austauschers zur Herstellung eines Medikaments zur Verhinderung von altersbedingten Organ-Dysfunktionen, altersbedingten Erkrankungen zur Lebensverlängerung
DE10036002A1 (de)	2000-07-25	2002-02-14	Aventis Cropscience Gmbh	Herbizide Mittel
WO2004099125A1 (de) *	2003-05-06	2004-11-18	Merck Patent Gmbh	Verfahren zur kristallisation von guanidinium-salzen
GB0520405D0 (en) *	2005-10-07	2005-11-16	Imp College Innovations Ltd	Biological agents and method
EP1844654A1 (de)	2006-03-29	2007-10-17	Bayer CropScience GmbH	Penetrationsförderer für agrochemische Wirkstoffe
DE102007013362A1 (de)	2007-03-16	2008-09-18	Bayer Cropscience Ag	Penetrationsförderer für herbizide Wirkstoffe
US20120101087A1 (en) *	2007-12-12	2012-04-26	Alberte Randall S	Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins
US20240000946A1 (en) *	2020-12-03	2024-01-04	Vilnius University	Carbonic anhydrase inhibitors synthesized on interconnecting linker chains

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US4065572A (en)	1976-02-13	1977-12-27	Merck & Co., Inc.	Amino acids and esters thereof useful as antihypertensive agents
US4170654A (en)	1976-02-13	1979-10-09	Merck & Co., Inc.	Antihypertensive compositions containing N-heterocyclicalanines and α-
US4206216A (en)	1976-02-13	1980-06-03	Merck & Co., Inc.	Antihypertensive N-heterocyclicalanines
US4156734A (en)	1976-02-13	1979-05-29	Merck & Co., Inc.	Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid
US4160835A (en)	1976-11-19	1979-07-10	Merck & Co., Inc.	Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid
GB1588096A (en) *	1978-05-20	1981-04-15	Wyeth & Bros Ltd John	Pyrrole derivatives
US4271187A (en)	1978-06-05	1981-06-02	Merck & Co., Inc.	Substituted phenyl alanine antihypertensive agents
US4544670A (en) *	1982-08-24	1985-10-01	William H. Rorer, Inc.	Method of treating coccidiosis with acyl guanidines
DE3929582A1 (de)	1989-09-06	1991-03-07	Hoechst Ag	Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
DK0556673T3 (da) *	1992-02-15	1998-04-14	Hoechst Ag	o-Substituerede benzoylguanidiner til behandling og profylakse af hjerterytmeforstyrrelser og iskæmisk inducerede skader samt til inhiberering af celleproliferation
DE59305042D1 (de)	1992-09-22	1997-02-20	Hoechst Ag	Benzoylguanidine, Verfahren zu ihrer Herstellung, sowie ihre Verwendung als Antiarrhythmika
EP0604852A1 (de)	1992-12-28	1994-07-06	Hoechst Aktiengesellschaft	2,4-Substituierte 5-(N-substituierte-Sulfamoyl)-Benzoylguanidine, als Antiarrythmika, Inhibitoren der Proliferationen von Zellen, und Inhibitoren des Natrium-Protonen-Antiporters
DE4404183A1 (de)	1994-02-10	1995-08-17	Merck Patent Gmbh	4-Amino-1-piperidylbenzoylguanidine
DE4421495A1 (de)	1994-06-20	1995-12-21	Merck Patent Gmbh	Heterocyclyloxy-benzoylguanidine
DE4430213A1 (de)	1994-08-28	1996-02-29	Merck Patent Gmbh	Arylbenzoylguanidine
DE4430916A1 (de)	1994-08-31	1996-03-07	Merck Patent Gmbh	Alkyl-benzoylguanidin-Derivate
DE4430861A1 (de)	1994-08-31	1996-03-07	Merck Patent Gmbh	Heterocyclyl-benzoylguanidine
DE4437874A1 (de)	1994-10-22	1996-04-25	Merck Patent Gmbh	Alkyl-5-methylsulfonyl-benzoylguanidin-Derivate
DE19502644A1 (de)	1995-01-28	1996-08-01	Merck Patent Gmbh	4-Amino-benzoylguanidin-Derivate
DE19502895A1 (de)	1995-01-31	1996-08-01	Merck Patent Gmbh	4-Mercapto-benzoylguanidin-Derivate
DE19517848A1 (de)	1995-05-16	1996-11-21	Merck Patent Gmbh	Fluorhaltige Benzoylguanidine
DE19529612A1 (de)	1995-08-11	1997-02-13	Merck Patent Gmbh	Sulfonyl- oder Sulfinyl-benzoylguanidin-Derivate
DE19531138A1 (de)	1995-08-24	1997-02-27	Merck Patent Gmbh	Alkenyl-benzoylguanidin-Derivate
DE19548708A1 (de)	1995-12-23	1997-06-26	Merck Patent Gmbh	Cyclische Sulfone
US6140563A (en)	1999-03-04	2000-10-31	Novartis Ag	Inbred maize line NP2151
US6410563B1 (en) *	1999-12-22	2002-06-25	Merck Frosst Canada & Co.	Substituted 8-arylquinoline phosphodiesterase-4 inhibitors
MY123585A (en)	2000-03-23	2006-05-31	Merck Canada Inc	Tri-aryl-substituted-ethane pde4 inhibitors.

1993
- 1993-08-24 DE DE4328352A patent/DE4328352A1/de not_active Withdrawn
1994
- 1994-08-18 PT PT94112895T patent/PT640587E/pt unknown
- 1994-08-18 AT AT94112895T patent/ATE188208T1/de active
- 1994-08-18 AT AT99102583T patent/ATE256105T1/de active
- 1994-08-18 DK DK94112895T patent/DK0640587T3/da active
- 1994-08-18 DE DE59410343T patent/DE59410343D1/de not_active Expired - Lifetime
- 1994-08-18 EP EP99102583A patent/EP0921117B2/de not_active Expired - Lifetime
- 1994-08-18 EP EP94112895A patent/EP0640587B1/de not_active Expired - Lifetime
- 1994-08-18 ES ES99102583T patent/ES2210872T5/es not_active Expired - Lifetime
- 1994-08-18 ES ES94112895T patent/ES2142895T3/es not_active Expired - Lifetime
- 1994-08-18 DE DE59409032T patent/DE59409032D1/de not_active Expired - Lifetime
- 1994-08-18 DK DK99102583T patent/DK0921117T4/da active
- 1994-08-18 PT PT99102583T patent/PT921117E/pt unknown
- 1994-08-22 FI FI943853A patent/FI120390B/fi not_active IP Right Cessation
- 1994-08-22 AU AU70397/94A patent/AU692776B2/en not_active Ceased
- 1994-08-22 NZ NZ264282A patent/NZ264282A/en not_active IP Right Cessation
- 1994-08-23 CA CA002546602A patent/CA2546602C/en not_active Expired - Lifetime
- 1994-08-23 NO NO943111A patent/NO302569B1/no not_active IP Right Cessation
- 1994-08-23 CA CA002130703A patent/CA2130703C/en not_active Expired - Lifetime
- 1994-08-23 JP JP21963594A patent/JP3790557B2/ja not_active Expired - Fee Related
- 1994-08-24 HU HU9402444A patent/HU223055B1/hu active IP Right Grant
- 1994-09-17 TW TW083107527A patent/TW469265B/zh not_active IP Right Cessation
1997
- 1997-04-18 US US08/837,460 patent/US6436999B1/en not_active Expired - Fee Related
1998
- 1998-05-19 AU AU67114/98A patent/AU6711498A/en not_active Withdrawn
- 1998-06-23 AU AU73143/98A patent/AU707538B2/en not_active Ceased
2000
- 2000-02-18 GR GR20000400383T patent/GR3032685T3/el unknown
- 2000-03-24 US US09/534,036 patent/US6632840B1/en not_active Expired - Fee Related
2001
- 2001-07-25 JP JP2001224010A patent/JP3775730B2/ja not_active Expired - Fee Related
2003
- 2003-08-15 US US10/641,058 patent/US20040044081A1/en not_active Abandoned

Also Published As

Publication number	Publication date
NO943111D0 (no)	1994-08-23
US6632840B1 (en)	2003-10-14
JP2002105043A (ja)	2002-04-10
ATE188208T1 (de)	2000-01-15
NO302569B1 (no)	1998-03-23
HK1021529A1 (en)	2000-06-16
EP0921117A3 (de)	1999-09-22
EP0921117B2 (de)	2009-01-07
CA2130703C (en)	2006-11-07
JP3775730B2 (ja)	2006-05-17
EP0921117B1 (de)	2003-12-10
FI943853A0 (fi)	1994-08-22
HK1011964A1 (en)	1999-07-23
ES2210872T5 (es)	2009-05-29
JPH0782234A (ja)	1995-03-28
PT640587E (pt)	2000-09-29
DE59410343D1 (de)	2004-01-22
FI943853L (fi)	1995-02-25
CA2130703A1 (en)	1995-02-25
DE4328352A1 (de)	1995-03-02
US6436999B1 (en)	2002-08-20
EP0921117A2 (de)	1999-06-09
ES2142895T3 (es)	2000-05-01
EP0640587A1 (de)	1995-03-01
DE59409032D1 (de)	2000-02-03
CA2546602A1 (en)	1995-02-25
TW469265B (en)	2001-12-21
CA2546602C (en)	2008-10-28
EP0640587B1 (de)	1999-12-29
FI120390B (fi)	2009-10-15
ES2210872T3 (es)	2004-07-01
GR3032685T3 (en)	2000-06-30
PT921117E (pt)	2004-04-30
JP3790557B2 (ja)	2006-06-28
NZ264282A (en)	1995-10-26
DK0921117T4 (da)	2009-05-11
AU7314398A (en)	1998-09-03
ATE256105T1 (de)	2003-12-15
DK0640587T3 (da)	2000-06-19
AU6711498A (en)	1998-07-09
HU9402444D0 (en)	1994-10-28
HU223055B1 (hu)	2004-03-01
NO943111L (no)	1995-02-27
AU692776B2 (en)	1998-06-18
AU7039794A (en)	1995-03-09
AU707538B2 (en)	1999-07-15
US20040044081A1 (en)	2004-03-04
HUT75532A (en)	1997-05-28

Publication	Publication Date	Title
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