DK0934261T3 - Fremgangsmåde til fremstilling af dithiobis-alkansulfonater og -phosphonater - Google Patents

Fremgangsmåde til fremstilling af dithiobis-alkansulfonater og -phosphonater

Info

Publication number: DK0934261T3
Authority: DK; Denmark
Prior art keywords: disulfides; alkanesulfonates; dithiobis; phosphonates; preparation
Prior art date: 1996-10-01

Application number

DK97942102T

Other languages

English (en)

Inventor

Kochat Haridas

Original Assignee

Bionumerik Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-01

Filing date

1997-09-23

Publication date

2001-11-19

1997-09-23 Application filed by Bionumerik Pharmaceuticals Inc filed Critical Bionumerik Pharmaceuticals Inc

2001-11-19 Application granted granted Critical

2001-11-19 Publication of DK0934261T3 publication Critical patent/DK0934261T3/da

Links

238000000034 method Methods 0.000 title abstract 4
ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 title 1
150000002019 disulfides Chemical class 0.000 abstract 3
BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
-1 alkenyl sulfonate salt Chemical class 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
229940044683 chemotherapy drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000000116 mitigating effect Effects 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
150000003057 platinum Chemical class 0.000 abstract 1
BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 abstract 1
230000002194 synthesizing effect Effects 0.000 abstract 1
229940126585 therapeutic drug Drugs 0.000 abstract 1
125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
- C07C319/24—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
- C07C319/04—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by addition of hydrogen sulfide or its salts to unsaturated compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/16—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of hydrogen sulfide or its salts to unsaturated compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK97942102T 1996-10-01 1997-09-23 Fremgangsmåde til fremstilling af dithiobis-alkansulfonater og -phosphonater DK0934261T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2821296P	1996-10-01	1996-10-01
PCT/GB1997/002576 WO1998014426A1 (en)	1996-10-01	1997-09-23	Process for producing mercaptoalkanesulfonates and phosphonates and derivatives thereof

Publications (1)

Publication Number	Publication Date
DK0934261T3 true DK0934261T3 (da)	2001-11-19

Family

ID=21842177

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97942102T DK0934261T3 (da)	1996-10-01	1997-09-23	Fremgangsmåde til fremstilling af dithiobis-alkansulfonater og -phosphonater

Country Status (12)

Country	Link
US (2)	US5808140A (da)
EP (1)	EP0934261B1 (da)
JP (1)	JP4104662B2 (da)
CN (1)	CN1082047C (da)
AT (1)	ATE207892T1 (da)
AU (1)	AU718575B2 (da)
CA (1)	CA2263204C (da)
DE (1)	DE69707911T2 (da)
DK (1)	DK0934261T3 (da)
ES (1)	ES2163197T3 (da)
PT (1)	PT934261E (da)
WO (1)	WO1998014426A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6160167A (en) *	1998-04-21	2000-12-12	Bionumerik Pharmaceuticals, Inc.	Mercaptans and disulfides
US6031006A (en) *	1999-10-21	2000-02-29	Bionumerik Pharmaceuticals, Inc.	Method of treating diabetic nephropathy
FR2811987A1 (fr) *	2000-07-18	2002-01-25	Expansia Sa	Procede de preparation du 2,2'-dithiobis(ethanesulfonate) de disodium
EP1322323A4 (en)	2000-09-11	2004-07-28	Therapro Technologies Inc	THIONIN AS AN ANTINEOPLASTIC AND IMMUNO-STIMULATING AGENT
US7034054B2 (en) *	2000-12-15	2006-04-25	Galileo Pharmaceuticals, Inc.	Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols
US7189775B2 (en)	2002-04-19	2007-03-13	Saint-Gobain Ceramics & Plastics, Inc.	Boehmite particles and polymer materials incorporating same
US7582277B2 (en)	2002-04-19	2009-09-01	Saint-Gobain Ceramics & Plastics, Inc.	Seeded boehmite particulate material and methods for forming same
US6504049B1 (en) *	2002-04-30	2003-01-07	Bionumerik Pharmaceuticals, Inc.	Process for synthesizing pharmaceutically active disulfide salts
US8710095B2 (en)	2002-04-30	2014-04-29	Bionumerik Pharmaceuticals, Inc.	Drugs for prophylaxis or mitigation of taxane-induced neurotoxicity
US6765148B2 (en)	2002-04-30	2004-07-20	Illinois Tool Works Inc.	C-shaped grommet
CA2548497C (en) *	2003-12-17	2009-06-09	Bionumerik Pharmaceuticals, Inc.	Process for synthesizing disulfides
US20050256055A1 (en) *	2004-05-12	2005-11-17	Hausheer Frederick H	Compounds and methods for reducing undesired toxicity of chemotherapeutic agents
US20060063742A1 (en) *	2004-09-21	2006-03-23	Hausheer Frederick H	Method of treatment for or protection against lymphedema
US7282602B2 (en) *	2004-09-21	2007-10-16	Bionumerik Pharmaceuticals, Inc.	Medicinal disulfide salts
JP5109081B2 (ja) *	2006-04-26	2012-12-26	東洋紡株式会社	アルケンスルホン酸塩を用いたチオカルボアルキルアルカンスルホン酸塩、メルカプトアルカンスルホン酸塩およびジチオビス（アルカンスルホン酸）塩の製造方法
JP5264904B2 (ja)	2007-08-03	2013-08-14	ユセベファルマソシエテアノニム	スルファニル誘導体、及び合成中間体としてのその使用
CN102014891B (zh)	2008-03-14	2013-12-18	比奥纽默里克药物公司	增加癌症患者存活时间的化合物的组合物和使用方法
US7924143B2 (en) *	2008-06-09	2011-04-12	Research In Motion Limited	System and method for providing tactile feedback to a user of an electronic device

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2517934A (en) *	1946-11-18	1950-08-08	Phillips Petroleum Co	Production of alkyl disulfide
NL270720A (da) *	1960-10-28
US3978137A (en) *	1975-03-14	1976-08-31	Universal Oil Products Company	Oxidation of sulfur-containing compounds
US3994979A (en) *	1975-05-01	1976-11-30	Phillips Petroleum Company	Disulfide process
US4670602A (en) *	1980-08-12	1987-06-02	Phillips Petroleum Co.	Method of making disulfides using a combination reaction vessel and aspirator-mixer
DE4127821A1 (de) *	1991-08-23	1993-02-25	Basf Ag	Disulfide, verfahren zu deren herstellung und deren verwendung

1997
- 1997-09-23 CN CN97198276A patent/CN1082047C/zh not_active Expired - Lifetime
- 1997-09-23 PT PT97942102T patent/PT934261E/pt unknown
- 1997-09-23 AU AU43902/97A patent/AU718575B2/en not_active Ceased
- 1997-09-23 CA CA002263204A patent/CA2263204C/en not_active Expired - Fee Related
- 1997-09-23 AT AT97942102T patent/ATE207892T1/de active
- 1997-09-23 DE DE69707911T patent/DE69707911T2/de not_active Expired - Lifetime
- 1997-09-23 JP JP51630298A patent/JP4104662B2/ja not_active Expired - Lifetime
- 1997-09-23 EP EP97942102A patent/EP0934261B1/en not_active Expired - Lifetime
- 1997-09-23 WO PCT/GB1997/002576 patent/WO1998014426A1/en not_active Ceased
- 1997-09-23 ES ES97942102T patent/ES2163197T3/es not_active Expired - Lifetime
- 1997-09-23 DK DK97942102T patent/DK0934261T3/da active
- 1997-09-24 US US08/935,463 patent/US5808140A/en not_active Expired - Lifetime
1998
- 1998-06-30 US US09/108,168 patent/US5922902A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2263204A1 (en)	1998-04-09
JP2001501219A (ja)	2001-01-30
US5922902A (en)	1999-07-13
ES2163197T3 (es)	2002-01-16
AU4390297A (en)	1998-04-24
WO1998014426A1 (en)	1998-04-09
EP0934261B1 (en)	2001-10-31
CN1231658A (zh)	1999-10-13
DE69707911D1 (de)	2001-12-06
JP4104662B2 (ja)	2008-06-18
AU718575B2 (en)	2000-04-13
PT934261E (pt)	2002-04-29
ATE207892T1 (de)	2001-11-15
CN1082047C (zh)	2002-04-03
DE69707911T2 (de)	2002-04-04
EP0934261A1 (en)	1999-08-11
US5808140A (en)	1998-09-15
CA2263204C (en)	2005-06-07

Publication	Publication Date	Title
DK0934261T3 (da)	2001-11-19	Fremgangsmåde til fremstilling af dithiobis-alkansulfonater og -phosphonater
DK0629608T3 (da)	1999-07-05	Fremgangsmåde til fremstilling af N-acyl-N,N',N'-ethylendiamintrieddikesyrederivater
ATE248824T1 (de)	2003-09-15	Substituierte phenylderivate, ihre herstellung und verwendung
NL300017I2 (nl)	2001-01-02	Gesubstitueerde androsta-1,4-dieen-3,17-dionen, alsmede farmaceutische preparaten die dergelijke verbindingen bevatten.
DK0630228T3 (da)	1998-06-02	Middel til regulering af hudens fedtethed
DZ1468A1 (fr)	2004-09-13	Composés nouveaux.
ES2188984T3 (es)	2003-07-01	Procedimiento de enriquecimiento en r de epimeros de derivados de 16,17-acetales de derivados de 21-aciloxi-pregnano-1,4-dieno-11-beta, 16alfa-triol-3,20-dionas.
ATE165827T1 (de)	1998-05-15	Herstellung von n-acetylneuraminsäure-derivaten
ATE305771T1 (de)	2005-10-15	Verfahren zur herstellung von vitaminpulvern
DE59509910D1 (de)	2002-01-17	Verfahren zur Herstellung von Alkylhydrogenchlorsilanen
DE59903314D1 (de)	2002-12-12	Perfluor-n-alkansulfonsäure-derivate
ES2109103T3 (es)	1998-01-01	Procedimiento para la preparacion de trialquilsilil-7 bacatina iii.
EA199900790A1 (ru)	2000-02-28	Способы получения пестицидных промежуточных соединений
DK0378455T3 (da)	1994-09-05	Fremgangsmåde til fremstilling af derivater af (+)-(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5H-1,5-benzothiazepine-4-on
FI872659A7 (fi)	1987-12-21	Menetelmä uusien androst-4-eeni-3,17-dionien valmistamiseksi.
ES2185196T3 (es)	2003-04-16	Un procedimiento para la preparacion de tetraazamacrociclos.
DE59712632D1 (de)	2006-06-01	Verfahren zur herstellung von 3-pyrrolin-2-carbonsäure-derivaten
FR2378518A1 (fr)	1978-08-25	Nouveaux medicaments a base de derives de tetrahydrodibenzopyranne
HUT61655A (en)	1993-03-01	Selective herbicide compositions containing salicylic acid derivatives as active components and process for producing the active components
DE69809433D1 (de)	2002-12-19	Herstellung von avermectin-verbindungen
ATE226585T1 (de)	2002-11-15	Thiazolobenzoheterocyclen, ihre herstellung und diese enthaltende phatrmazeutische zubereitungen
ATE196292T1 (de)	2000-09-15	Zwischenprodukte um 2-imidazolin-5onederivate herzustellen.
EP1028721A4 (en)	2001-01-31	N, N'-BIS (SULFONYL) HYDRAZINES FOR USE AS ANTINEOPLASTIC AGENTS
FI872489A7 (fi)	1987-12-07	Menetelmä uusien aralkyyli -imidatsolijohdannaisten valmistamiseksi.
PT1064265E (pt)	2004-07-30	Sintese de 3-amino-2-cloro-4-metilpiridina a partir de malononitrilo e acetona