DK0939638T3 - Injektionsformuleringer af avermectiner og milbemyciner - Google Patents

Injektionsformuleringer af avermectiner og milbemyciner

Info

Publication number: DK0939638T3
Authority: DK; Denmark
Prior art keywords: milbemycins; avermectins; injection formulations; formulations; injection
Prior art date: 1996-09-18

Application number

DK97944849T

Other languages

English (en)

Inventor

Michael Grosse-Bley

Richard Kujanek

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-18

Filing date

1997-09-08

Publication date

2003-03-24

1997-09-08 Application filed by Bayer Ag filed Critical Bayer Ag

2003-03-24 Application granted granted Critical

2003-03-24 Publication of DK0939638T3 publication Critical patent/DK0939638T3/da

Links

239000005660 Abamectin Substances 0.000 title 1
238000009472 formulation Methods 0.000 title 1
238000002347 injection Methods 0.000 title 1
239000007924 injection Substances 0.000 title 1
FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 title 1
ZLBGSRMUSVULIE-GSMJGMFJSA-N milbemycin A3 Chemical class O1[C@H](C)[C@@H](C)CC[C@@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 ZLBGSRMUSVULIE-GSMJGMFJSA-N 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Tropical Medicine & Parasitology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)

DK97944849T 1996-09-18 1997-09-08 Injektionsformuleringer af avermectiner og milbemyciner DK0939638T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19638045A DE19638045A1 (de)	1996-09-18	1996-09-18	Injektionsformulierungen von Avermectinen und Milbemycinen
PCT/EP1997/004867 WO1998011902A1 (de)	1996-09-18	1997-09-08	Injektionsformulierungen von avermectinen und milbemycinen

Publications (1)

Publication Number	Publication Date
DK0939638T3 true DK0939638T3 (da)	2003-03-24

Family

ID=7806009

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97944849T DK0939638T3 (da)	1996-09-18	1997-09-08	Injektionsformuleringer af avermectiner og milbemyciner

Country Status (17)

Country	Link
US (1)	US6617314B2 (da)
EP (1)	EP0939638B1 (da)
JP (1)	JP4822196B2 (da)
KR (1)	KR20000035978A (da)
CN (1)	CN1130203C (da)
AR (1)	AR008844A1 (da)
AT (1)	ATE228845T1 (da)
AU (1)	AU750874B2 (da)
BR (2)	BR9712058B1 (da)
CA (1)	CA2265952C (da)
DE (2)	DE19638045A1 (da)
DK (1)	DK0939638T3 (da)
ES (1)	ES2184135T3 (da)
NZ (1)	NZ334673A (da)
PL (1)	PL332137A1 (da)
WO (1)	WO1998011902A1 (da)
ZA (1)	ZA978352B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6458373B1 (en)	1997-01-07	2002-10-01	Sonus Pharmaceuticals, Inc.	Emulsion vehicle for poorly soluble drugs
US7030155B2 (en)	1998-06-05	2006-04-18	Sonus Pharmaceuticals, Inc.	Emulsion vehicle for poorly soluble drugs
KR20000025762A (ko) *	1998-10-14	2000-05-06	유충식	이버멕틴류의 가용화 조성물
GB9827727D0 (en)	1998-12-16	1999-02-10	Pfizer Ltd	Antiparasitic formulations
GB0000313D0 (en)	2000-01-10	2000-03-01	Astrazeneca Uk Ltd	Formulation
AU781682B2 (en)	2000-03-20	2005-06-09	Zoetis Services Llc	Sustained-release compositions for parenteral administration
US6872708B2 (en) *	2001-09-10	2005-03-29	Mitsukazu Matsumoto	Local injection prescription
US7396819B2 (en) *	2003-08-08	2008-07-08	Virbac Corporation	Anthelmintic formulations
WO2005094210A2 (en)	2004-03-12	2005-10-13	The Hartz Mountain Corporation	Multi-action anthelmintic formulations
NZ590141A (en) *	2008-06-24	2012-05-25	Merial Ltd	Anthelminthic formulations including castor oil and another vegetable oil
ES2399228T3 (es) *	2009-02-16	2013-03-26	Ah Usa 42 Llc	Formulación de doramectina a dosis elevada
CN101773467B (zh) *	2010-01-20	2015-09-09	北京大北农动物保健科技有限责任公司	一种美贝霉素或美贝霉素肟的兽用缓释注射液及制备方法
US20110223208A1 (en) *	2010-03-09	2011-09-15	Beth Hill	Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations
CA2792517C (en) *	2010-03-09	2020-03-24	Janssen Biotech, Inc.	Non-aqueous high concentration reduced viscosity suspension formulations
US9072668B2 (en)	2010-03-09	2015-07-07	Janssen Biotech, Inc.	Non-aqueous high concentration reduced viscosity suspension formulations of antibodies
CA2867079A1 (en) *	2012-03-13	2013-09-19	Bayer New Zealand Limited	Long acting compositions
CN103417478B (zh) *	2012-05-18	2014-09-10	中国农业科学院兰州畜牧与兽药研究所	一种以水为基质的伊维菌素o/w型注射液及其制备方法
WO2017119928A1 (en) *	2016-01-08	2017-07-13	Abon Pharmaceuticals, Llc	Long acting injectable formulations
US20210137960A1 (en)	2018-02-01	2021-05-13	Yale University	Compositions and methods for inhibition of nuclear-penetrating antibodies
CN114107097B (zh) *	2021-11-10	2024-03-05	河北兴柏农业科技股份有限公司	一种阿佛曼链霉菌活性孢子的固体发酵工艺

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
OA06863A (fr) *	1980-08-04	1983-02-28	Merck & Co Inc	Solubilisation de l'invermectine dans l'eau.
NZ210505A (en) *	1983-12-22	1988-06-30	Merck & Co Inc	Parasiticidal compositions containing avermectin or milbemycin derivatives
US6001822A (en) *	1989-04-11	1999-12-14	Pfizer Inc.	Antiparasitic formulations
DK0393890T3 (da) *	1989-04-11	1992-09-28	Pfizer	Injicerbart præparat indeholdende 25-cyclohexyl-avermectin B1
NZ234802A (en) *	1989-08-14	1992-11-25	Merck & Co Inc	Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals
US5055486A (en)	1989-12-22	1991-10-08	American Cyanamid Company	13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
US5030650A (en)	1989-09-11	1991-07-09	American Cyanamid Company	13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
DE69208765T2 (de) *	1991-07-23	1996-09-26	American Cyanamid Co	Stabile Zusammensetzungen für parenterale Verabrechung und ihre Verwendung
ATE180671T1 (de) *	1991-09-30	1999-06-15	Merck & Co Inc	Hydrierte rizinusöl-enthaltende injizierbare formulierungen mit verlängerter wirkstoffabgabe
GB2275193A (en) *	1993-02-17	1994-08-24	Merck & Co Inc	Formulations for the topical delivery of avermectins
DE4443888A1 (de) *	1994-12-09	1996-06-13	Bayer Ag	Dermal applizierbare Formulierungen von Parasitiziden
EP0873127B1 (en) *	1995-09-25	2006-11-15	Ashmont Holdings Limited	Anthelmintic macrocyclic lactone compositions
DE19613972A1 (de) *	1996-04-09	1997-10-16	Bayer Ag	Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
RU2140737C1 (ru) *	1998-09-22	1999-11-10	Мосин Владимир Александрович	Средство для профилактики и лечения паразитарных заболеваний животных
CN1219393A (zh) *	1998-11-13	1999-06-16	王玉万	一种含阿维菌素或伊维菌素的兽用抗寄生虫油剂口服液及其制备方法

1996
- 1996-09-18 DE DE19638045A patent/DE19638045A1/de not_active Withdrawn
1997
- 1997-09-08 JP JP51423798A patent/JP4822196B2/ja not_active Expired - Fee Related
- 1997-09-08 CA CA002265952A patent/CA2265952C/en not_active Expired - Lifetime
- 1997-09-08 DE DE59708905T patent/DE59708905D1/de not_active Expired - Lifetime
- 1997-09-08 KR KR1019997001893A patent/KR20000035978A/ko not_active Withdrawn
- 1997-09-08 CN CN97198028A patent/CN1130203C/zh not_active Expired - Fee Related
- 1997-09-08 EP EP97944849A patent/EP0939638B1/de not_active Expired - Lifetime
- 1997-09-08 AU AU46215/97A patent/AU750874B2/en not_active Ceased
- 1997-09-08 BR BRPI9712058-8A patent/BR9712058B1/pt not_active IP Right Cessation
- 1997-09-08 WO PCT/EP1997/004867 patent/WO1998011902A1/de not_active Ceased
- 1997-09-08 US US09/254,615 patent/US6617314B2/en not_active Expired - Lifetime
- 1997-09-08 ES ES97944849T patent/ES2184135T3/es not_active Expired - Lifetime
- 1997-09-08 DK DK97944849T patent/DK0939638T3/da active
- 1997-09-08 BR BRPI9715298A patent/BRPI9715298B8/pt not_active IP Right Cessation
- 1997-09-08 NZ NZ334673A patent/NZ334673A/xx not_active IP Right Cessation
- 1997-09-08 PL PL97332137A patent/PL332137A1/xx unknown
- 1997-09-08 AT AT97944849T patent/ATE228845T1/de active
- 1997-09-17 ZA ZA9708352A patent/ZA978352B/xx unknown
- 1997-09-18 AR ARP970104297A patent/AR008844A1/es active IP Right Grant

Also Published As

Publication number	Publication date
BR9712058B1 (pt)	2009-05-05
JP4822196B2 (ja)	2011-11-24
CN1130203C (zh)	2003-12-10
CN1230890A (zh)	1999-10-06
NZ334673A (en)	2000-10-27
EP0939638B1 (de)	2002-12-04
CA2265952C (en)	2009-11-17
US20020160967A1 (en)	2002-10-31
US6617314B2 (en)	2003-09-09
EP0939638A1 (de)	1999-09-08
ZA978352B (en)	1998-03-24
AR008844A1 (es)	2000-02-23
AU4621597A (en)	1998-04-14
AU750874B2 (en)	2002-08-01
JP2001503029A (ja)	2001-03-06
ATE228845T1 (de)	2002-12-15
PL332137A1 (en)	1999-08-30
KR20000035978A (ko)	2000-06-26
CA2265952A1 (en)	1998-03-26
HK1022845A1 (en)	2000-08-25
ES2184135T3 (es)	2003-04-01
BRPI9715298B8 (pt)	2016-04-26
WO1998011902A1 (de)	1998-03-26
DE59708905D1 (de)	2003-01-16
DE19638045A1 (de)	1998-03-19
BR9715298B1 (pt)	2014-10-14
BR9712058A (pt)	1999-08-24

Publication	Publication Date	Title
NO983965D0 (no)	1998-08-28	Polymer-organoleire-kompositter og deres fremstilling
ATE228845T1 (de)	2002-12-15	Injektionsformulierungen von avermectinen und milbemycinen
DK0806895T3 (da)	2000-07-17	Insecticide kombinationer omfattende et insecticid af chlornicotinyl-familien og et insecticid med pyrazzol-, pyrrol- eller
NO981967L (no)	1998-06-30	Stabile fryset°rkede farmas°ytiske formuleringer
DK0941067T3 (da)	2003-11-17	Stabile glasagtige pulverformuleringer
DE69736467D1 (de)	2006-09-21	Hochfrequenz-gespeiste dilatorhülse
DK0915880T3 (da)	2008-02-11	Azolotriaziner og pyrimidiner
DE69630221D1 (de)	2003-11-06	Stabile alkoholisch-wässrige zusammensetzung
NO952832L (no)	1995-07-28	Nye antiparasittiske midler beslektet med milbemyciner og avermektiner
DK0969844T3 (da)	2009-02-16	Indgivelse af et injicerbart antibiotikum i öret af et dyr
NO20006488D0 (no)	2000-12-19	Sammensetning og anvendelse
NO961721D0 (no)	1996-04-29	2-oksetanon-limingsmidler, deres fremstilling og bruk
DE69725482D1 (de)	2003-11-20	Härtbare Siliconzusammensetzungen
NO991771D0 (no)	1999-04-14	Sprengstoff-formuleringer
DE69723552D1 (de)	2003-08-21	Hockeyschläger
ITRM920606A0 (it)	1992-08-14	Preparazione enzimatica stabile
PT826679E (pt)	2002-04-29	Compostos de naftilo intermediarios composicoes e metodos de utilizacao
DK1140068T3 (da)	2004-07-12	Doramectin formulations
DE69627514D1 (de)	2003-05-22	Hockeyschläger
NO984921D0 (no)	1998-10-22	Tienopyridinderivater og deres anvendelse
FR2753102B3 (fr)	1998-10-30	Bille intra-orbitaire
NO983556D0 (no)	1998-08-03	Formulering og anvendelse
NO972821D0 (no)	1997-06-18	1-C-perfluoralkylglycosider, deres fremstilling og anvendelse
DK0896534T3 (da)	2005-03-21	Injektionsformuleringer af avermectiner og milbemyciner på basis af ricinusolie
ID23774A (id)	2000-05-11	Komposisi insektisida