DK0966277T3 - Anvendelse af R-NSAID'er til forebyggelse af Alzheimer's sygdom - Google Patents

Anvendelse af R-NSAID'er til forebyggelse af Alzheimer's sygdom

Info

Publication number
DK0966277T3
DK0966277T3 DK98908904T DK98908904T DK0966277T3 DK 0966277 T3 DK0966277 T3 DK 0966277T3 DK 98908904 T DK98908904 T DK 98908904T DK 98908904 T DK98908904 T DK 98908904T DK 0966277 T3 DK0966277 T3 DK 0966277T3
Authority
DK
Denmark
Prior art keywords
disease
nsaids
prevent alzheimer
alzheimer
nsaid
Prior art date
Application number
DK98908904T
Other languages
Danish (da)
English (en)
Inventor
William J Wechter
John D Mccracken
Original Assignee
Univ Loma Linda Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/814,490 external-priority patent/US6160018A/en
Application filed by Univ Loma Linda Med filed Critical Univ Loma Linda Med
Application granted granted Critical
Publication of DK0966277T3 publication Critical patent/DK0966277T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98908904T 1997-03-10 1998-03-04 Anvendelse af R-NSAID'er til forebyggelse af Alzheimer's sygdom DK0966277T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/814,490 US6160018A (en) 1995-03-13 1997-03-10 Prophylactic composition and method for alzheimer's Disease

Publications (1)

Publication Number Publication Date
DK0966277T3 true DK0966277T3 (da) 2006-03-27

Family

ID=25215202

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98908904T DK0966277T3 (da) 1997-03-10 1998-03-04 Anvendelse af R-NSAID'er til forebyggelse af Alzheimer's sygdom

Country Status (9)

Country Link
EP (2) EP0966277B1 (fr)
JP (1) JP2001514655A (fr)
AT (2) ATE446748T1 (fr)
AU (1) AU6682298A (fr)
CA (1) CA2283255C (fr)
DE (2) DE69832695T2 (fr)
DK (1) DK0966277T3 (fr)
ES (1) ES2253810T3 (fr)
WO (1) WO1998040061A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2163986B1 (es) * 1999-07-13 2003-02-16 Menarini Lab Acidos-alfa-arilpropionicos y arilaceticos como inhibidores de la ciclooxigenasa-ii.
JP2003530437A (ja) * 2000-04-13 2003-10-14 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ Ａβ４２低下物質
CA2499599A1 (fr) * 2002-09-17 2004-04-01 New York University Procedes pour traiter les alterations de la memoire liees a l'age (aami), les deficits cognitifs legers (mci) et les demences au moyen d'inhibiteurs du cycle cellulaire
WO2004032845A2 (fr) * 2002-10-07 2004-04-22 Encore Pharmaceuticals, Inc. Esters de r-enantiomeres d'anti-inflammatoires non-steroidiens et leur utilisation
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
US8110681B2 (en) * 2006-03-17 2012-02-07 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Compounds for the treatment of spinal muscular atrophy and other uses
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20100173960A1 (en) * 2006-09-21 2010-07-08 Antonio Cruz The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases
KR20150058566A (ko) * 2007-06-04 2015-05-28 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 ｎｓａｉａ 약물전구체 및 이들의 새로운 의약적 용도
BR122021011394B1 (pt) 2008-12-04 2021-09-28 Chongxi Yu Composição de alta penetração de um fármaco principal, e uso de uma hpc
CN111012914A (zh) 2012-01-18 2020-04-17 苏州泰飞尔医药有限公司 治疗肺部疾病的高穿透力前药组合物和医药组合物
CA3112130A1 (fr) 2013-07-11 2015-01-15 University Of North Texas Health Science Center At Fort Worth Depistage base sur le sang pour la detection d'une maladie neurologique dans des installations de soins primaires
AU2014354808A1 (en) 2013-11-26 2016-06-02 University Of North Texas Health Science Center At Fort Worth Personalized medicine approach for treating cognitive loss
WO2019143562A1 (fr) 2018-01-18 2019-07-25 University Of North Texas Health Science Center At Fort Worth Diagnostic compagnon pour ains et donépézil pour le traitement de sous-populations spécifiques de patients souffrant de la maladie d'alzheimer
EP4076424A1 (fr) * 2019-12-20 2022-10-26 Basf Se Composition pour le traitement de maladies associées à l'amyloïde bêta

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
US5192753A (en) * 1991-04-23 1993-03-09 Mcgeer Patrick L Anti-rheumatoid arthritic drugs in the treatment of dementia
FR2687915B1 (fr) * 1992-02-28 1995-05-05 Rhone Poulenc Rorer Sa Composition pharmaceutique utilisable comme analgesique contenant l'acide (benzoyl-3 phenyl)-2 propionique-(r).
US5331000A (en) * 1992-03-09 1994-07-19 Sepracor Inc. Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen
US5382591A (en) * 1992-12-17 1995-01-17 Sepracor Inc. Antipyretic and analgesic methods using optically pure R-ketorolac
US6160018A (en) * 1995-03-13 2000-12-12 Loma Linda University Medical Center Prophylactic composition and method for alzheimer's Disease
US5955504A (en) * 1995-03-13 1999-09-21 Loma Linda University Medical Center Colorectal chemoprotective composition and method of preventing colorectal cancer
WO1997048391A2 (fr) * 1996-06-21 1997-12-24 Advanced Research And Technology Institute Methodes et compositions a base de r-ibuprofene

Also Published As

Publication number Publication date
EP0966277A1 (fr) 1999-12-29
DE69832695D1 (de) 2006-01-12
AU6682298A (en) 1998-09-29
EP1642575A1 (fr) 2006-04-05
EP1642575B1 (fr) 2009-10-28
JP2001514655A (ja) 2001-09-11
ES2253810T3 (es) 2006-06-01
DE69832695T2 (de) 2006-09-14
CA2283255C (fr) 2007-01-02
CA2283255A1 (fr) 1998-09-17
WO1998040061A1 (fr) 1998-09-17
ATE311865T1 (de) 2005-12-15
ATE446748T1 (de) 2009-11-15
DE69841267D1 (de) 2009-12-10
EP0966277B1 (fr) 2005-12-07

Similar Documents

Publication Publication Date Title
DK0966277T3 (da) Anvendelse af R-NSAID'er til forebyggelse af Alzheimer's sygdom
TR200000129T2 (tr) Yepyeni spiroazabisiklik heterosiklik bileşikler.
ID24487A (id) Senyawa-senyawa benzosikloheptatiofen
FI912621A7 (fi) Farmakologisesti aktiivisia keskushermostoon vaikuttavia yhdisteitä
BR0002073A (pt) Processo para a preparação de um composto quiral
FI885346L (fi) Ergolinderivat, som foerhindrar parkinsons sjukdom.
IT1302243B1 (it) Sintesi dell'1,1,1,3,3-pentafluoropropano.
DE69808440D1 (de) Verwendung von (+)mefloquine zur behandlung von malaria
DE60128100D1 (de) Analgetisches arzneimittel
ES2177024T3 (es) Empleo de la fanquinoma para el tratamiento de la enfermedaad de alzheimer.
DZ1576A1 (fr) Compostions therapeutiques à base de dérives de 1,2-dithiole-3-thione.
DK0424156T3 (da) Behandling af hepatobiliær sygdom med 15-ketoprostaglandinforbindelser
FI912622A7 (fi) Farmakologisesti aktiivisia keskushermostoon vaikuttavia yhdisteitä
WO2000010554A3 (fr) Procedes et compositions employant le vigabatrin s(+) optiquement pur
ITTO20000674A0 (it) Composizioni a base di aminoacidi, atte al trattamento dell'insufficienza cardiaca.
DK0896822T3 (da) 4-aminopyrrol (3,2-d) pyrimidiner som neuropeptide Y receptorantagonister
WO2002099422A3 (fr) Personnalisation de therapie avec des agents de la maladie d'alzheimer
IT1296613B1 (it) Farmaco per la cura dell'ircismo contenente un adrenocorticosteroide.
EE200200215A (et) 2-amino-3,4-dihüdrokinasoliinide kasutamine ravimi valmistamiseks, mis on ette nähtud isheemilistest seisunditest tingitud haiguste raviks või ennetamiseks
SE9501773D0 (sv) New use
MXPA02002486A (es) Uso de dexrazoxano para tratar la psoriasis.
FR2680953B1 (fr) Semelle deodorante, antibacteries, hydrothermique jetable.
SE9304236D0 (sv) New use
NO970190D0 (no) Preparat til behandling av Parkinsons sykdom
FI961410A7 (fi) Farmakologisesti aktiivisia keskushermostoon vaikuttavia yhdisteitä