DK0969822T3 - Bestemmelse af et organs eller vævs tilbøjelighed til cancer ved bestemmelse af dets prægningsmønster - Google Patents
Bestemmelse af et organs eller vævs tilbøjelighed til cancer ved bestemmelse af dets prægningsmønsterInfo
- Publication number
- DK0969822T3 DK0969822T3 DK97953486T DK97953486T DK0969822T3 DK 0969822 T3 DK0969822 T3 DK 0969822T3 DK 97953486 T DK97953486 T DK 97953486T DK 97953486 T DK97953486 T DK 97953486T DK 0969822 T3 DK0969822 T3 DK 0969822T3
- Authority
- DK
- Denmark
- Prior art keywords
- imprinting
- methods
- restoring
- normal
- compositions
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 210000000056 organ Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002831 pharmacologic agent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3409596P | 1996-12-30 | 1996-12-30 | |
| PCT/US1997/023991 WO1998029108A2 (en) | 1996-12-30 | 1997-12-29 | Compositions and methods for restoring a normal pattern of imprinting to cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0969822T3 true DK0969822T3 (da) | 2003-07-21 |
Family
ID=21874277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97953486T DK0969822T3 (da) | 1996-12-30 | 1997-12-29 | Bestemmelse af et organs eller vævs tilbøjelighed til cancer ved bestemmelse af dets prægningsmønster |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0969822B1 (da) |
| JP (2) | JP4913270B2 (da) |
| AT (1) | ATE235190T1 (da) |
| AU (1) | AU5722398A (da) |
| CA (1) | CA2276306C (da) |
| DE (1) | DE69720283T2 (da) |
| DK (1) | DK0969822T3 (da) |
| ES (1) | ES2195196T3 (da) |
| WO (1) | WO1998029108A2 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6803195B1 (en) * | 1999-07-02 | 2004-10-12 | Ramot At Tel-Aviv University Ltd. | Facile detection of cancer and cancer risk based on level of coordination between alleles |
| GB0107267D0 (en) * | 2001-03-23 | 2001-05-16 | Babraham Inst | Diagnostic method for determining the methylation state of cloned embryos |
| US6982253B2 (en) | 2002-06-05 | 2006-01-03 | Supergen, Inc. | Liquid formulation of decitabine and use of the same |
| AU2002952944A0 (en) * | 2002-11-27 | 2002-12-12 | Human Genetic Signatures Pty Ltd | Restoration of methylation states in cells |
| WO2004111266A1 (en) | 2003-06-17 | 2004-12-23 | Human Genetic Signatures Pty Ltd | Methods for genome amplification |
| CA2537810C (en) | 2003-09-04 | 2012-12-18 | Human Genetic Signatures Pty Ltd | Nucleic acid detection assay |
| US8168777B2 (en) | 2004-04-29 | 2012-05-01 | Human Genetic Signatures Pty. Ltd. | Bisulphite reagent treatment of nucleic acid |
| WO2006026828A1 (en) | 2004-09-10 | 2006-03-16 | Human Genetic Signatures Pty Ltd | Amplification blocker comprising intercalating nucleic acids (tna) containing intercalating pseudonucleotides (ipn) |
| CN101111606B (zh) | 2004-12-03 | 2012-05-16 | 人类遗传标记控股有限公司 | 通过化学修饰胞嘧啶而简化微生物核酸的方法 |
| EP1883707B1 (en) | 2005-05-26 | 2014-04-09 | Human Genetic Signatures PTY Ltd | Isothermal strand displacement amplification using primers containing a non-regular base |
| CA2621932A1 (en) | 2005-09-14 | 2007-03-22 | Human Genetic Signatures Pty Ltd | Assay for hpv and methylated genomic dna targets to screen for cervical cancer |
| GB0607063D0 (en) | 2006-04-07 | 2006-05-17 | Cellcentric Ltd | Compositions and methods for epigenetic modification of nucleic acid sequences in vivo |
| CA2706740C (en) | 2007-11-27 | 2017-01-17 | Human Genetic Signatures Pty Ltd | Enzymes for amplification and copying bisulphite modified nucleic acids |
| KR101912488B1 (ko) | 2011-09-07 | 2018-10-26 | 휴먼 제네틱 시그너처스 피티와이 엘티디 | 분자 검출 분석법 |
| WO2018214249A1 (zh) * | 2017-05-22 | 2018-11-29 | 立森印迹诊断技术（无锡）有限公司 | 一种印记基因分级模型及其组成的系统和应用 |
| CN112313345B (zh) * | 2018-05-18 | 2024-02-20 | 立森印迹诊断技术（无锡）有限公司 | 一种通过活检细胞样本诊断癌症的方法 |
| CN110714075B (zh) * | 2018-07-13 | 2024-05-03 | 立森印迹诊断技术（无锡）有限公司 | 一种用于检测肺肿瘤良恶性程度的分级模型及其应用 |
| CN110791563B (zh) * | 2018-08-01 | 2024-02-09 | 立森印迹诊断技术（无锡）有限公司 | 一种用于检测甲状腺肿瘤良恶性程度的分级模型及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58177949A (ja) * | 1982-04-12 | 1983-10-18 | Takeda Chem Ind Ltd | ランカシジン群抗生物質包接化合物 |
| JPS61176523A (ja) * | 1985-01-30 | 1986-08-08 | Teruhiko Beppu | 制癌剤 |
| EP0631584A4 (en) * | 1991-02-28 | 1998-07-01 | Dana Farber Cancer Inst Inc | DIAGNOSIS AND THERAPY OF CANCER. |
| US5616609A (en) * | 1991-08-08 | 1997-04-01 | Ikekawa; Tetsuro | Carcinostatic compound and production thereof |
| US5356903A (en) * | 1993-04-22 | 1994-10-18 | Sterling Winthrop Inc. | 1-cyclopropyl-4-pyridyl-quinolines |
-
1997
- 1997-12-29 CA CA002276306A patent/CA2276306C/en not_active Expired - Lifetime
- 1997-12-29 DE DE69720283T patent/DE69720283T2/de not_active Expired - Lifetime
- 1997-12-29 WO PCT/US1997/023991 patent/WO1998029108A2/en not_active Ceased
- 1997-12-29 EP EP97953486A patent/EP0969822B1/en not_active Expired - Lifetime
- 1997-12-29 JP JP53025498A patent/JP4913270B2/ja not_active Expired - Lifetime
- 1997-12-29 AU AU57223/98A patent/AU5722398A/en not_active Abandoned
- 1997-12-29 DK DK97953486T patent/DK0969822T3/da active
- 1997-12-29 AT AT97953486T patent/ATE235190T1/de not_active IP Right Cessation
- 1997-12-29 ES ES97953486T patent/ES2195196T3/es not_active Expired - Lifetime
-
2008
- 2008-10-23 JP JP2008272942A patent/JP2009072197A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001507703A (ja) | 2001-06-12 |
| AU5722398A (en) | 1998-07-31 |
| DE69720283T2 (de) | 2004-01-29 |
| ES2195196T3 (es) | 2003-12-01 |
| EP0969822B1 (en) | 2003-03-26 |
| JP4913270B2 (ja) | 2012-04-11 |
| JP2009072197A (ja) | 2009-04-09 |
| WO1998029108A2 (en) | 1998-07-09 |
| CA2276306A1 (en) | 1998-07-09 |
| DE69720283D1 (de) | 2003-04-30 |
| ATE235190T1 (de) | 2003-04-15 |
| WO1998029108A3 (en) | 1999-02-18 |
| CA2276306C (en) | 2009-12-15 |
| EP0969822A2 (en) | 2000-01-12 |
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