DK0973785T3 - Trans-platinforbindelse og diagnostisk kit - Google Patents

Trans-platinforbindelse og diagnostisk kit

Info

Publication number
DK0973785T3
DK0973785T3 DK98912826T DK98912826T DK0973785T3 DK 0973785 T3 DK0973785 T3 DK 0973785T3 DK 98912826 T DK98912826 T DK 98912826T DK 98912826 T DK98912826 T DK 98912826T DK 0973785 T3 DK0973785 T3 DK 0973785T3
Authority
DK
Denmark
Prior art keywords
trans
diagnostic kit
platinum compound
bio
attachment
Prior art date
Application number
DK98912826T
Other languages
Danish (da)
English (en)
Inventor
Jan Reedijk
Herman H Volkers
Robert Jochem Heetebrij
Hendrik Jan Houthoff
Original Assignee
Kreatech Biotech Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kreatech Biotech Bv filed Critical Kreatech Biotech Bv
Priority claimed from PCT/NL1998/000206 external-priority patent/WO1998045304A1/en
Application granted granted Critical
Publication of DK0973785T3 publication Critical patent/DK0973785T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Interface Circuits In Exchanges (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98912826T 1997-04-10 1998-04-09 Trans-platinforbindelse og diagnostisk kit DK0973785T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201066A EP0870770A1 (de) 1997-04-10 1997-04-10 Trans-Platinverbindung, ein diese enthaltender, diagnostischer Kit, und ein Verfahren zur Markierung von bioorganischen Molekülen
PCT/NL1998/000206 WO1998045304A1 (en) 1997-04-10 1998-04-09 Trans-platinum compound, and diagnostic kit

Publications (1)

Publication Number Publication Date
DK0973785T3 true DK0973785T3 (da) 2004-04-05

Family

ID=8228196

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98912826T DK0973785T3 (da) 1997-04-10 1998-04-09 Trans-platinforbindelse og diagnostisk kit

Country Status (11)

Country Link
US (1) US6248531B1 (de)
EP (1) EP0870770A1 (de)
JP (1) JP4212652B2 (de)
AT (1) ATE255587T1 (de)
AU (1) AU737441B2 (de)
CA (1) CA2286668C (de)
DE (1) DE69820244T2 (de)
DK (1) DK0973785T3 (de)
ES (1) ES2212279T3 (de)
NZ (1) NZ500184A (de)
PT (1) PT973785E (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2425663C (en) * 2000-10-11 2009-12-29 Applera Corporation Fluorescent nucleobase conjugates having anionic linkers
CA2498713A1 (en) * 2002-09-17 2004-04-01 Richard Abraham Joseph Real-time detection of nucleic acid reactions
US7138520B2 (en) * 2003-01-13 2006-11-21 Massachusetts Institute Of Technology Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
CA2531123A1 (en) * 2003-07-02 2005-01-13 Perkinelmer Las, Inc. Assay and process for labeling and detection of micro rna and small interfering rna sequences
EP1669760A1 (de) * 2004-12-08 2006-06-14 Kreatech Biotechnology B.V. Markierte Übergangsmetall-Komplexe
EP1745802A1 (de) * 2005-07-20 2007-01-24 Kreatech Biotechnology B.V. Verfahren zur Konjugierung therapeutischer Verbindungen an zellgezielten Gruppen über Metallkomplexen
JP6120416B2 (ja) 2012-01-06 2017-04-26 リンクシス ビー.ヴイ. 細胞標的コンジュゲートを調製するための方法、及び得られる錯体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5107007A (en) * 1989-09-01 1992-04-21 The University Of Vermont And State Agricultural College Bis-platinum complexes as chemotherapeutic agents
US5624919A (en) * 1993-09-14 1997-04-29 The University Of Vermont And State Agricultural College Trans platinum (IV) complexes
US5521289A (en) * 1994-07-29 1996-05-28 Nanoprobes, Inc. Small organometallic probes
DE69629403T2 (de) * 1995-05-09 2004-06-24 Kreatech Biotechnology B.V. Verfahren zur herstellung von linkern zwischen markierungsgruppen und bio-organischen molekülen auf der basis von platin für die markierung von bio-organischen molekülen zur entdeckung interessanter biologischer substanzen

Also Published As

Publication number Publication date
CA2286668A1 (en) 1998-10-15
US6248531B1 (en) 2001-06-19
PT973785E (pt) 2004-04-30
AU737441B2 (en) 2001-08-16
DE69820244T2 (de) 2004-09-09
ES2212279T3 (es) 2004-07-16
JP4212652B2 (ja) 2009-01-21
CA2286668C (en) 2008-05-06
EP0870770A1 (de) 1998-10-14
DE69820244D1 (de) 2004-01-15
AU6751798A (en) 1998-10-30
NZ500184A (en) 2001-08-31
JP2001521511A (ja) 2001-11-06
ATE255587T1 (de) 2003-12-15

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