DK0973895T3 - Transskriptionsfaktor Islet-Brain 1 (IB1) - Google Patents

Transskriptionsfaktor Islet-Brain 1 (IB1)

Info

Publication number: DK0973895T3
Authority: DK; Denmark
Prior art keywords: brain; transcription factor; glut2; human; disclosed
Prior art date: 1997-04-03

Application number

DK98913958T

Other languages

English (en)

Inventor

Gerard Waeber

Christophe Bonny

Original Assignee

Xigen Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-03

Filing date

1998-04-02

Publication date

2008-04-28

1997-04-03 Priority claimed from GBGB9706731.8A external-priority patent/GB9706731D0/en

1997-05-15 Priority claimed from GBGB9709920.4A external-priority patent/GB9709920D0/en

1998-04-02 Application filed by Xigen Sa filed Critical Xigen Sa

2008-04-28 Application granted granted Critical

2008-04-28 Publication of DK0973895T3 publication Critical patent/DK0973895T3/da

Links

101710105206 C-Jun-amino-terminal kinase-interacting protein 1 Proteins 0.000 title abstract 4
102100022291 C-Jun-amino-terminal kinase-interacting protein 1 Human genes 0.000 title abstract 4
102000040945 Transcription factor Human genes 0.000 title 1
108091023040 Transcription factor Proteins 0.000 title 1
102000058058 Glucose Transporter Type 2 Human genes 0.000 abstract 2
101001046660 Homo sapiens C-Jun-amino-terminal kinase-interacting protein 1 Proteins 0.000 abstract 2
108090001061 Insulin Proteins 0.000 abstract 2
108091006299 SLC2A2 Proteins 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 2
239000002299 complementary DNA Substances 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
206010012289 Dementia Diseases 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
208000012902 Nervous system disease Diseases 0.000 abstract 1
208000025966 Neurological disease Diseases 0.000 abstract 1
208000027089 Parkinsonian disease Diseases 0.000 abstract 1
206010034010 Parkinsonism Diseases 0.000 abstract 1
101001046655 Rattus norvegicus C-Jun-amino-terminal kinase-interacting protein 1 Proteins 0.000 abstract 1
101100341613 Rattus norvegicus Mapk8ip1 gene Proteins 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
230000006907 apoptotic process Effects 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
238000012512 characterization method Methods 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
102000054579 human MAPK8IP1 Human genes 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
108091006106 transcriptional activators Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Apparatus For Radiation Diagnosis (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

DK98913958T 1997-04-03 1998-04-02 Transskriptionsfaktor Islet-Brain 1 (IB1) DK0973895T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9706731.8A GB9706731D0 (en)	1997-04-03	1997-04-03	Transcription factor islet-brain (IBI)
GBGB9709920.4A GB9709920D0 (en)	1997-05-15	1997-05-15	Transcription factor islet-brain 1 (B1)
PCT/GB1998/000972 WO1998044106A1 (en)	1997-04-03	1998-04-02	Transcription factor islet-brain 1 (ib1)

Publications (1)

Publication Number	Publication Date
DK0973895T3 true DK0973895T3 (da)	2008-04-28

Family

ID=26311309

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98913958T DK0973895T3 (da)	1997-04-03	1998-04-02	Transskriptionsfaktor Islet-Brain 1 (IB1)

Country Status (9)

Country	Link
US (2)	US5880261A (da)
EP (3)	EP0973895B1 (da)
AT (2)	ATE517993T1 (da)
AU (1)	AU6847298A (da)
DE (1)	DE69838905T2 (da)
DK (1)	DK0973895T3 (da)
ES (1)	ES2299205T3 (da)
PT (1)	PT973895E (da)
WO (1)	WO1998044106A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6043083A (en)	1997-04-28	2000-03-28	Davis; Roger J.	Inhibitors of the JNK signal transduction pathway and methods of use
US6525187B1 (en) *	1998-07-31	2003-02-25	Diagnostic Products Corporation	Polynucleotide encoding autoantigens associated with endometriosis
US20060019879A1 (en) *	1998-07-31	2006-01-26	El Shami A S	Polynucleotide encoding autoantigens associated with endometriosis
US20060019878A1 (en) *	1998-07-31	2006-01-26	El Shami A S	Polynucleotide encoding autoantigens associated with endometriosis
US6610820B1 (en) *	1999-10-12	2003-08-26	University Of Lausanne	Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US20030108539A1 (en) *	2000-02-14	2003-06-12	Christophe Bonny	Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US20040082509A1 (en)	1999-10-12	2004-04-29	Christophe Bonny	Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US8183339B1 (en)	1999-10-12	2012-05-22	Xigen S.A.	Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US6716824B1 (en) *	1999-10-22	2004-04-06	F. Charles Brunicardi	Treatment of pancreatic adenocarcinoma by cytotoxic gene therapy
US7208581B1 (en) *	1999-11-05	2007-04-24	The Burnham Institute	TRAF family proteins
US7157227B2 (en) *	2000-03-31	2007-01-02	University Of Louisville Research Foundation	Microarrays to screen regulatory genes
US6642003B2 (en)	2001-08-02	2003-11-04	Cedars-Sinai Medical Center	Human glucose-dependent insulin-secreting cell line
US7141240B2 (en) *	2002-03-12	2006-11-28	Cedars-Sinai Medical Center	Glucose-dependent insulin-secreting cells transfected with a nucleotide sequence encoding GLP-1
US20060223807A1 (en)	2005-03-29	2006-10-05	University Of Massachusetts Medical School, A Massachusetts Corporation	Therapeutic methods for type I diabetes
WO2007031098A1 (en) *	2005-09-12	2007-03-22	Xigen S.A.	Cell-permeable peptide inhibitors of the jnk signal transduction pathway
US8080517B2 (en) *	2005-09-12	2011-12-20	Xigen Sa	Cell-permeable peptide inhibitors of the JNK signal transduction pathway
WO2009143865A1 (en) *	2008-05-30	2009-12-03	Xigen S.A.	Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2009143864A1 (en) *	2008-05-30	2009-12-03	Xigen S.A.	Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
WO2010072228A1 (en)	2008-12-22	2010-07-01	Xigen S.A.	Novel transporter constructs and transporter cargo conjugate molecules
JP5457813B2 (ja) *	2009-12-16	2014-04-02	ルネサスエレクトロニクス株式会社	Ａｄｐｌｌ回路、半導体装置及び携帯情報機器
WO2011160653A1 (en)	2010-06-21	2011-12-29	Xigen S.A.	Novel jnk inhibitor molecules
WO2012048721A1 (en)	2010-10-14	2012-04-19	Xigen S.A.	Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
WO2013091670A1 (en)	2011-12-21	2013-06-27	Xigen S.A.	Novel jnk inhibitor molecules for treatment of various diseases
KR20160023669A (ko)	2013-06-26	2016-03-03	자이겐 인플라메이션 리미티드	다양한 질병의 치료를 위한 jnk 신호 전달 경로의 세포 투과성 펩타이드 억제자의 새로운 용도
WO2014206427A1 (en)	2013-06-26	2014-12-31	Xigen Inflammation Ltd.	New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2015197097A1 (en)	2014-06-26	2015-12-30	Xigen Inflammation Ltd.	New use for jnk inhibitor molecules for treatment of various diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0679716A4 (en) *	1993-11-12	1999-06-09	Kenichi Matsubara	GENE SIGNATURE.

1997
- 1997-05-20 US US08/859,201 patent/US5880261A/en not_active Expired - Lifetime
1998
- 1998-04-02 AT AT07019868T patent/ATE517993T1/de not_active IP Right Cessation
- 1998-04-02 AT AT98913958T patent/ATE382087T1/de not_active IP Right Cessation
- 1998-04-02 WO PCT/GB1998/000972 patent/WO1998044106A1/en not_active Ceased
- 1998-04-02 DK DK98913958T patent/DK0973895T3/da active
- 1998-04-02 EP EP98913958A patent/EP0973895B1/en not_active Expired - Lifetime
- 1998-04-02 ES ES98913958T patent/ES2299205T3/es not_active Expired - Lifetime
- 1998-04-02 AU AU68472/98A patent/AU6847298A/en not_active Abandoned
- 1998-04-02 EP EP07019868A patent/EP1889913B1/en not_active Expired - Lifetime
- 1998-04-02 EP EP07008419A patent/EP1889912A1/en not_active Withdrawn
- 1998-04-02 PT PT98913958T patent/PT973895E/pt unknown
- 1998-04-02 US US09/402,214 patent/US6620914B1/en not_active Expired - Lifetime
- 1998-04-02 DE DE69838905T patent/DE69838905T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0973895A1 (en)	2000-01-26
DE69838905D1 (de)	2008-02-07
WO1998044106A1 (en)	1998-10-08
EP1889912A1 (en)	2008-02-20
EP0973895B1 (en)	2007-12-26
EP1889913A1 (en)	2008-02-20
ATE382087T1 (de)	2008-01-15
AU6847298A (en)	1998-10-22
EP1889913B1 (en)	2011-07-27
DE69838905T2 (de)	2008-12-11
US6620914B1 (en)	2003-09-16
ATE517993T1 (de)	2011-08-15
PT973895E (pt)	2008-01-29
ES2299205T3 (es)	2008-05-16
US5880261A (en)	1999-03-09

Publication	Publication Date	Title
ATE517993T1 (de)	2011-08-15	Transkriptionsfaktor islet-brain 1 (ib1)
Gallagher et al.	2006	The ARF tumour suppressor
EP0935001A4 (en)	2000-08-23	NEW VEGF-LIKE FACTORS
UA39161C2 (uk)	2001-06-15	Рекомбінантний білок gm-csf для збільшення продукції гранулоцитів і макрофагів у пацієнтів, вектор і кднк, що його кодують
DE69836131D1 (de)	2006-11-23	Neue menschliche delta3-zusammensetzung und deren therapeutische und diagnostische verwendungen
ES8401777A1 (es)	1984-01-01	Procedimiento para producir un polipeptido.
HUP0002095A2 (hu)	2000-10-28	Vegyületek prosztatarák immunterápiás kezelésére és alkalmazásuk
ATE365796T1 (de)	2007-07-15	Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
WO1998049300A3 (en)	1999-03-11	Truncated vegf-related proteins
HUP0100436A2 (hu)	2001-06-28	Emlős citokinszerű polipeptid-10
ATE418563T1 (de)	2009-01-15	Nik proteine, nukleinsäure sowie verfahren
ATE355381T1 (de)	2006-03-15	Verfahren zur induzierung von genexpression mittels ionisierender strahlung
EP1291422A3 (de)	2003-03-19	Menschliche Nukleinsäuresequenzen aus Ovartumorgewebe
WO2004050894A3 (en)	2006-08-10	Heart failure gene determination and therapeutic screening
PL350417A1 (en)	2002-12-16	Vascular adhesion molecules and modulation of their function
DE69233507D1 (de)	2005-06-16	Hbgad und higad polypeptide und nukleinsäuren und deren verwendung zur diagnose und behandlung von gad autoantigen assoziierten krankheiten
Bossak-Ahmad et al.	2021	Ternary Cu2+ Complexes of Human Serum Albumin and Glycyl-l-histidyl-l-lysine
ATE88500T1 (de)	1993-05-15	Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel.
EP0192175A3 (de)	1988-01-20	Polypeptide des Rhinovirusstammes HRV2 sowie die hierfür codierenden DNA-Moleküle
ATE463508T1 (de)	2010-04-15	Reagentien und verfahren zur erkennung von erkrankungen der brust
ATE507296T1 (de)	2011-05-15	Verwendung von fibroblasten-wachstumsfaktor- fragmenten
FI863626A0 (fi)	1986-09-09	Dna-sekvenser, rekombinant-dna -molekyler och foerfaranden foer framstaellning av polypeptider som liknar humant lipokortin.
ATE163651T1 (de)	1998-03-15	Neues menschliches, rekombinantes interferon gamma
DE69534705D1 (de)	2006-01-26	Dickdarm spezifische gene und proteine
WO2004050860A3 (en)	2005-06-02	Compositions, splice variants and methods relating to colon specific genes and proteins