DK0983070T3 - Forhindring af ovariecancer ved indgivelser ef en vitamin D forbindelse - Google Patents

Forhindring af ovariecancer ved indgivelser ef en vitamin D forbindelse

Info

Publication number: DK0983070T3
Authority: DK; Denmark
Prior art keywords: vitamin; compound; ovarian cancer; administration; prevention
Prior art date: 1997-06-11

Application number

DK98926371T

Other languages

English (en)

Inventor

Gustavo C Rodriguez

Regina S Whitaker

Original Assignee

Gustavo C Rodriguez

Regina S Whitaker

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-11

Filing date

1998-06-05

Publication date

2007-02-05

1998-06-05 Application filed by Gustavo C Rodriguez, Regina S Whitaker filed Critical Gustavo C Rodriguez

2007-02-05 Application granted granted Critical

2007-02-05 Publication of DK0983070T3 publication Critical patent/DK0983070T3/da

Links

206010033128 Ovarian cancer Diseases 0.000 title abstract 2
229930003316 Vitamin D Natural products 0.000 title abstract 2
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 2
235000019166 vitamin D Nutrition 0.000 title abstract 2
239000011710 vitamin D Substances 0.000 title abstract 2
-1 vitamin D compound Chemical class 0.000 title abstract 2
229940046008 vitamin d Drugs 0.000 title abstract 2
206010061535 Ovarian neoplasm Diseases 0.000 title 1
230000002265 prevention Effects 0.000 title 1
208000007571 Ovarian Epithelial Carcinoma Diseases 0.000 abstract 1
230000006907 apoptotic process Effects 0.000 abstract 1
210000002919 epithelial cell Anatomy 0.000 abstract 1
230000001613 neoplastic effect Effects 0.000 abstract 1
230000002611 ovarian Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK98926371T 1997-06-11 1998-06-05 Forhindring af ovariecancer ved indgivelser ef en vitamin D forbindelse DK0983070T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/873,010 US6034074A (en)	1996-09-13	1997-06-11	Prevention of ovarian cancer by administration of a Vitamin D compound
PCT/US1998/011737 WO1998056389A1 (en)	1997-06-11	1998-06-05	Prevention of ovarian cancer by administration of a vitamin d compound

Publications (1)

Publication Number	Publication Date
DK0983070T3 true DK0983070T3 (da)	2007-02-05

Family

ID=25360805

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98926371T DK0983070T3 (da)	1997-06-11	1998-06-05	Forhindring af ovariecancer ved indgivelser ef en vitamin D forbindelse

Country Status (11)

Country	Link
US (3)	US6034074A (da)
EP (2)	EP0983070B1 (da)
AT (1)	ATE342058T1 (da)
AU (1)	AU7822298A (da)
CA (1)	CA2293582A1 (da)
CY (1)	CY1105909T1 (da)
DE (1)	DE69836134T2 (da)
DK (1)	DK0983070T3 (da)
ES (1)	ES2275307T3 (da)
PT (1)	PT983070E (da)
WO (1)	WO1998056389A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6538037B2 (en)	1991-01-08	2003-03-25	Bone Care International, Inc.	Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US20040167106A1 (en) *	1993-06-04	2004-08-26	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of a Vitamin D compound
US6407082B1 (en) *	1996-09-13	2002-06-18	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a vitamin D compound
US6034074A (en)	1996-09-13	2000-03-07	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en)	1996-09-13	2000-02-22	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of progestin products
US6511970B1 (en)	1996-09-13	2003-01-28	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6765002B2 (en)	2000-03-21	2004-07-20	Gustavo Rodriguez	Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6573256B2 (en)	1996-12-30	2003-06-03	Bone Care International, Inc.	Method of inhibiting angiogenesis using active vitamin D analogues
US6566353B2 (en)	1996-12-30	2003-05-20	Bone Care International, Inc.	Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6503893B2 (en)	1996-12-30	2003-01-07	Bone Care International, Inc.	Method of treating hyperproliferative diseases using active vitamin D analogues
US6087350A (en) *	1997-08-29	2000-07-11	University Of Pittsburgh Of The Commonwealth System Of Higher Education	Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
ES2368824T3 (es) *	1998-03-27	2011-11-22	Oregon Health & Science University	Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos.
US20010044431A1 (en) *	2000-03-21	2001-11-22	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20050113351A1 (en) *	2000-03-21	2005-05-26	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20040176336A1 (en) *	2000-03-21	2004-09-09	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20050004007A1 (en) *	2000-09-12	2005-01-06	Steven Grant	Promotion of adoptosis in cancer cells by co-administration of cyclin dependent kinase inhibitiors and cellular differentiation agents
US7361664B2 (en) *	2001-06-20	2008-04-22	The United States Of America As Represented By The Department Of Health And Human Services	Vitamin D receptor antagonists and related compositions and methods of use
JP2005515996A (ja) *	2001-12-03	2005-06-02	ノバセアインコーポレイティッド	活性型ビタミンｄ化合物を含む薬学的組成物
US20050026877A1 (en) *	2002-12-03	2005-02-03	Novacea, Inc.	Pharmaceutical compositions comprising active vitamin D compounds
US20050020546A1 (en) *	2003-06-11	2005-01-27	Novacea, Inc.	Pharmaceutical compositions comprising active vitamin D compounds
US7094775B2 (en)	2004-06-30	2006-08-22	Bone Care International, Llc	Method of treating breast cancer using a combination of vitamin D analogues and other agents
PT2435825E (pt)	2009-05-27	2015-11-02	Biotempus Ltd	Métodos para o tratamento de doenças
AU2010332283B2 (en) *	2009-12-17	2014-06-12	Mayo Foundation For Medical Education And Research	Determination of favorable time(s) for chemotherapy delivery
CN120899726A (zh) *	2024-05-06	2025-11-07	华南理工大学	维生素d在制备避免化疗致卵巢损伤的保护药物中的应用

Family Cites Families (93)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3608075A (en)	1969-07-28	1971-09-21	American Home Prod	Compositions and methods of treating the menopausal syndrome
US3969502A (en)	1972-04-14	1976-07-13	Schering Aktiengesellschaft	Method for contraception by the administration of sequential contraceptive preparations
DE2365103C3 (de)	1973-12-21	1980-08-28	Schering Ag, 1000 Berlin Und 4619 Bergkamen	V erwendung von Hormonen zur Kontrazeption
US4390531A (en)	1981-08-10	1983-06-28	Syntex Pharmaceuticals International Ltd.	Method of contraception using peak progestogen dosage
US4921843A (en)	1988-10-20	1990-05-01	Pasquale Samuel A	Contraception system and method
US4530839A (en)	1983-09-26	1985-07-23	Ortho Pharmaceutical Corporation	Triphasic oral contraceptive
US4628051A (en)	1983-09-26	1986-12-09	Ortho Pharmaceutical Corporation	Triphasic oral contraceptive
US4544554A (en)	1983-09-26	1985-10-01	Ortho Pharmaceutical Corporation	Triphasic oral contraceptive
US4616006A (en)	1983-09-26	1986-10-07	Ortho Pharmaceutical Corporation	Triphasic oral contraceptive
US4933184A (en)	1983-12-22	1990-06-12	American Home Products Corp. (Del)	Menthol enhancement of transdermal drug delivery
DE3347125A1 (de)	1983-12-22	1985-07-11	Schering AG, 1000 Berlin und 4709 Bergkamen	Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption
US4931283A (en)	1983-12-22	1990-06-05	American Home Products Corp. (Del)	Menthol enhancement of transdermal drug delivery
US4760053A (en)	1984-08-02	1988-07-26	Fernand Labrie	Combination therapy for selected sex steroid dependent cancers
US4962098A (en)	1987-06-15	1990-10-09	Warner-Lambert Company	Graduated estrogen contraceptive
US4594340A (en) *	1984-11-29	1986-06-10	Hoffmann-La Roche Inc.	25,26-dehydro-1α,24R-dihydroxycholecalciferol and 25,26-dehydro-1α,24S-dihydroxycholecalciferol and the epimeric mixture
GB8503940D0 (en)	1985-02-15	1985-03-20	Erba Farmitalia	4-substituted androstendione derivatives
US4800198A (en) *	1985-04-23	1989-01-24	Wisconsin Alumni Research Foundation	Method of inducing the differentiation of malignant cells with secosterol
GB8517360D0 (en)	1985-07-09	1985-08-14	Erba Farmitalia	Substituted androsta-1,4-diene-3,17-diones
US4817819A (en)	1985-12-19	1989-04-04	Berlex Laboratories, Inc.	Container for tablets
GB8531747D0 (en)	1985-12-24	1986-02-05	Erba Farmitalia	10beta-alkynylestrene derivatives
GB8615092D0 (en)	1986-06-20	1986-07-23	Erba Farmitalia	Androst-4-ene-317-diones
IE61236B1 (en)	1986-07-15	1994-10-19	American Home Prod	Combination dosage form for pre-menopausal women
DE3625315A1 (de)	1986-07-25	1988-01-28	Schering Ag	11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate
US4833125A (en) *	1986-12-05	1989-05-23	The General Hospital Corporation	Method of increasing bone mass
DE3702383A1 (de)	1987-01-23	1988-08-04	Schering Ag	11ss-alkinylestrene und -estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
US5108995A (en)	1987-09-24	1992-04-28	Jencap Research Ltd.	Hormone preparation and method
US5256421A (en)	1987-09-24	1993-10-26	Jencap Research Ltd.	Hormone preparation and method
US5276022A (en)	1987-09-24	1994-01-04	Jencap Research Ltd.	Hormone preparation and method
US5422119A (en)	1987-09-24	1995-06-06	Jencap Research Ltd.	Transdermal hormone replacement therapy
BE1004905A4 (fr)	1987-12-30	1993-02-23	Roussel Uclaf	Nouveaux derives 17beta-oh 19-nor steroides substitues en 17alpha, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
US4780497A (en)	1988-02-12	1988-10-25	The B. F. Goodrich Company	Reduced melt viscosity CPVC blends containing sulfur and various metal carbonate stabilizers
KR0144358B1 (ko) *	1988-04-21	1998-07-15	피. 라이달 크리스텐슨	비타민 d 동족체
US5246925A (en) *	1989-03-09	1993-09-21	Wisconsin Alumni Research Foundation	19-nor-vitamin D compounds for use in treating hyperparathyroidism
US5364847A (en)	1989-03-10	1994-11-15	Endorecherche	Inhibitors of sex steroid biosynthesis and methods for their production and use
US5401731A (en) *	1989-06-29	1995-03-28	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab)	Vitamin D analogues
GB8915770D0 (en) *	1989-07-10	1989-08-31	Leo Pharm Prod Ltd	Chemical compounds
US4954790A (en)	1989-11-15	1990-09-04	Avantek, Inc.	Enhanced coupled, even mode terminated baluns, and mixers and modulators constructed therefrom
GB8929059D0 (en) *	1989-12-22	1990-02-28	Leo Pharm Prod Ltd	Chemical compounds
FR2656310B1 (fr)	1989-12-22	1992-05-07	Roussel Uclaf	Nouveaux produits sterouides comportant en position 10, un radical thioethyle substitue, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
FR2656309B1 (fr)	1989-12-22	1992-05-07	Roussel Uclaf	Nouveaux produits sterouides comportant en position 10, un radical ethyle substitue, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
US5532228A (en) *	1990-02-06	1996-07-02	Schering Aktiengesellschaft	Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents
US5227375A (en)	1990-02-08	1993-07-13	Endorecherche, Inc.	Aromatase inhibitors
GB9007236D0 (en) *	1990-03-30	1990-05-30	Leo Pharm Prod Ltd	Chemical compounds
US5314694A (en)	1990-10-29	1994-05-24	Alza Corporation	Transdermal formulations, methods and devices
IE71203B1 (en)	1990-12-13	1997-02-12	Akzo Nv	Low estrogen oral contraceptives
IE62665B1 (en)	1990-12-17	1995-02-22	Akzo Nv	Contraceptive regimen
IE71202B1 (en)	1990-12-17	1997-02-12	Akzo Nv	Progestagen-only contraceptive
DE4101953A1 (de) *	1991-01-19	1992-07-23	Schering Ag	23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
CH681153A5 (de)	1991-01-28	1993-01-29	Marigen S.A.	Neue sterolester- und sterolphosphorverbindungen.
DE4104385C1 (da)	1991-02-09	1992-08-13	Marika Dr.Med. 6509 Framersheim De Ehrlich
US5278155A (en) *	1991-06-05	1994-01-11	Daikin Industries, Ltd.	Fluorine-containing vitamin D3 analogues and cell differentiation-inducing agent containing the same
HU222501B1 (hu)	1991-06-28	2003-07-28	Endorecherche Inc.	MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
ZA924811B (en)	1991-06-28	1993-12-29	Endorecherche Inc	Controlled release systems and low dose androgens
DE4141746A1 (de) *	1991-12-13	1993-06-17	Schering Ag	20-methyl-substituierte vitamin d-derivate
US5210081A (en)	1992-02-26	1993-05-11	American Home Products Corporation	Alkali metal 8,9-dehydroestrone sulfate esters
US5274142A (en) *	1992-03-12	1993-12-28	The Johns Hopkins University	Vitamin D3 analogues
CA2096105A1 (en) *	1992-10-07	1994-04-08	Enrico Giuseppe Baggiolini (Deceased)	Vitamin d3 fluorinated analogs
GB9226877D0 (en) *	1992-12-23	1993-02-17	Leo Pharm Prod Ltd	Chemical compounds
WO1994019365A1 (en)	1993-02-18	1994-09-01	Farmitalia Carlo Erba Srl	Fluorinated 4-aminoandrostadienone derivatives and process for their preparation
US5468736A (en)	1993-02-25	1995-11-21	The Medical College Of Hampton Road	Hormone replacement therapy
US5547947A (en) *	1993-03-11	1996-08-20	Hoffmann-La Roche Inc.	Methods of treatment
DE4308406C1 (de)	1993-03-12	1994-06-16	Jenapharm Gmbh	Kombinationspräparat zur Kontrazeption
DE69400495T2 (de) *	1993-04-05	1997-04-30	Wisconsin Alumni Res Found	19-Nor-vitamin-D3-Verbindung mit einem Substituent an die 2. Stelle
US5380720A (en) *	1993-05-11	1995-01-10	Wisconsin Alumni Research Foundation	Iodo vitamin D3 compounds and method for preparing same
US5486511A (en)	1993-05-25	1996-01-23	Merrell Dow Pharmaceuticals Inc.	4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase
US5595970A (en)	1993-07-16	1997-01-21	Schering Aktiengesellschaft	Treatment of climacteric disorders with nitric oxide synthase substrates and/or donors
US5565589A (en) *	1993-11-03	1996-10-15	Wisconsin Alumni Research Foundation	17-formyl-5,6-trans-vitamin D compounds
US5373004A (en) *	1993-11-24	1994-12-13	Wisconsin Alumni Research Foundation	26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
US5428029A (en) *	1993-11-24	1995-06-27	Hoffmann-La Roche Inc.	Vitamin D3 fluorinated analogs
US5811416A (en)	1994-06-06	1998-09-22	Board Of Regents The University Of Texas System	Endothelin antagonist and/or endothelin synthase inhibitor in combination with a progestin, an estrogen, a cyclooxygenase inhibitor, or a nitric acid donor or substrate
US5633011A (en)	1994-08-04	1997-05-27	Alza Corporation	Progesterone replacement therapy
IL115659A (en)	1994-10-27	2000-06-01	Akzo Nobel Nv	Steroids with a 17-spiromethylene lactone or lactol group process for their preparation and pharmaceutical compositions containing them
IL116433A (en)	1994-12-19	2002-02-10	Galen Chemicals Ltd	INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS
CN1188189C (zh)	1995-06-07	2005-02-09	奥瑟－麦内尔制药公司	基质层含有17－脱乙酰基诺孕酯的经皮贴片及基质的用途
US5897539A (en)	1995-09-28	1999-04-27	Schering Aktiengesellschaft	Hormone replacement therapy method and hormone dispenser
US5998137A (en)	1996-01-17	1999-12-07	Grainger; David J.	Methods of diagnosis by detecting polymorphisms in the TGF-β1 promoter
GB9604305D0 (en)	1996-02-29	1996-05-01	Ralston Stuart H	Diagnostic method and apparatus
US5898038A (en)	1996-03-19	1999-04-27	Board Of Regents, The University Of Texas System	Treatment of osteoporosis and metabolic bone disorders with nitric oxide substrate and/or donors
US5827876A (en)	1996-04-09	1998-10-27	American Home Products Corporation	Inhibition of bone loss by 3-(4-acrylamidobenzoyl) benzo b!-thiophenes
US5880137A (en)	1996-04-19	1999-03-09	American Home Products Corporation	2-phenyl-1- 4-(amino-1-yl-alk-1-ynyl)-benzyl!-1H-indol-5-ols as estrogenic agents
US5985910A (en)	1996-04-19	1999-11-16	American Home Products Corporation	3- [4- (2- Phenyl-Indole-1-ylmethyl) Phenyl]- Acrylamides as estrogenic agents
US5747480A (en)	1996-05-08	1998-05-05	American Home Products Corporation	Oral contraceptive
US5783208A (en)	1996-07-19	1998-07-21	Theratech, Inc.	Transdermal drug delivery matrix for coadministering estradiol and another steroid
US5858405A (en)	1996-07-26	1999-01-12	American Home Products Corporation	Oral contraceptive
US5888543A (en)	1996-07-26	1999-03-30	American Home Products Corporation	Oral contraceptives
US6028064A (en)	1996-09-13	2000-02-22	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of progestin products
US6034074A (en)	1996-09-13	2000-03-07	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a Vitamin D compound
US5994337A (en)	1997-01-13	1999-11-30	Wake Forest University	Effects of 17α-dihydroequilenin on plasma lipid and lipoprotein, glucose, insulin concentrations, coronary artery vasomotor function, and reproductive organ and mammary gland proliferation in atherosclerotic mammals
US5948775A (en)	1997-03-19	1999-09-07	American Home Products Corporation	2- or 3-(substitutedaminoalkoxyphenyl)quinazolin-4-ones
US5891868A (en)	1997-11-21	1999-04-06	Kaiser Foundation Health Plan, Inc.	Methods for treating postmenopausal women using ultra-low doses of estrogen
US6001846A (en)	1998-02-17	1999-12-14	Ligand Pharmaceuticals Incorporated	Process for the preparation of 1,2-dihydroquinolines
US6020328A (en)	1998-03-06	2000-02-01	Research Triangle Institute	20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US5962444A (en)	1998-05-29	1999-10-05	Research Triangle Institute	17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties

1997
- 1997-06-11 US US08/873,010 patent/US6034074A/en not_active Expired - Fee Related
1998
- 1998-06-05 PT PT98926371T patent/PT983070E/pt unknown
- 1998-06-05 AU AU78222/98A patent/AU7822298A/en not_active Abandoned
- 1998-06-05 AT AT98926371T patent/ATE342058T1/de not_active IP Right Cessation
- 1998-06-05 WO PCT/US1998/011737 patent/WO1998056389A1/en not_active Ceased
- 1998-06-05 ES ES98926371T patent/ES2275307T3/es not_active Expired - Lifetime
- 1998-06-05 DK DK98926371T patent/DK0983070T3/da active
- 1998-06-05 CA CA002293582A patent/CA2293582A1/en not_active Abandoned
- 1998-06-05 EP EP98926371A patent/EP0983070B1/en not_active Expired - Lifetime
- 1998-06-05 DE DE69836134T patent/DE69836134T2/de not_active Expired - Fee Related
- 1998-06-05 EP EP06021120A patent/EP1782814A1/en not_active Withdrawn
2000
- 2000-01-07 US US09/479,021 patent/US6444658B1/en not_active Expired - Fee Related
2007
- 2007-01-08 CY CY20071100022T patent/CY1105909T1/el unknown
- 2007-10-31 US US11/931,951 patent/US20080171731A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US6444658B1 (en)	2002-09-03
CA2293582A1 (en)	1998-12-17
WO1998056389A1 (en)	1998-12-17
CY1105909T1 (el)	2011-02-02
AU7822298A (en)	1998-12-30
EP0983070A1 (en)	2000-03-08
DE69836134D1 (de)	2006-11-23
US20080171731A1 (en)	2008-07-17
ES2275307T3 (es)	2007-06-01
DE69836134T2 (de)	2007-08-23
ATE342058T1 (de)	2006-11-15
EP0983070B1 (en)	2006-10-11
EP1782814A1 (en)	2007-05-09
PT983070E (pt)	2007-02-28
US6034074A (en)	2000-03-07

Publication	Publication Date	Title
DK0983070T3 (da)	2007-02-05	Forhindring af ovariecancer ved indgivelser ef en vitamin D forbindelse
BG106738A (en)	2003-02-28	A method for chemoprevention of prostate cancer
DK1224172T3 (da)	2007-08-13	Medikamenter til behandling af ondartede tumorer
DK1163349T3 (da)	2008-06-23	Medicinske præparater til behandling af alfa-galactosidase A-mangel
EA199900373A2 (ru)	1999-12-29	Фармацевтические композиции
MY107158A (en)	1995-09-30	3-arylcarbonyl; -1h-indoles useful as therapeutic agents.
WO1999039740A3 (en)	1999-10-28	Sensitizing cells to compounds using lipid-mediated gene and compound delivery
BR0109703A (pt)	2003-02-04	Derivados de piperazina
BR0114917A (pt)	2003-07-01	Inibidores de pirimidina-2,4,6-triona metaloproteinase
TR200102800T2 (tr)	2002-01-21	Yeni bileşikler.
BR0213424A (pt)	2004-12-14	Uso aperfeiçoado de composto antitumoral na terapia contra câncer
DK0725637T3 (da)	2001-03-26	Parenteralt busulfan til behandling af malign sygdom
AU2251901A (en)	2001-07-03	Methods and compounds for inhibiting MRP1
DK1369115T3 (da)	2007-01-02	Fremgangsmåder til forebyggelse af brystcancer ved administration af raloxifen
ATE297904T1 (de)	2005-07-15	Halo-alkoxycarbonylverbindungen
NO20021409D0 (no)	2002-03-21	Hastighets-kontrollerte partikler
NZ333281A (en)	2000-03-27	Asymmetric stilbene compounds for use as sun protection agents
ATE305771T1 (de)	2005-10-15	Verfahren zur herstellung von vitaminpulvern
GB2378948B (en)	2004-11-10	Novel compounds for modulating cell proliferation
DK0842165T3 (da)	2001-08-06	Thiazolidin-4-carboxylsyrederivater som cytobeskyttende midler
DE69019035D1 (de)	1995-06-08	Stabilisierte fettlösliche Vitaminzusammensetzungen.
HN1998000193A (es)	2000-04-05	Compuestos de triazina
ES2179529T3 (es)	2003-01-16	Compuestos biaromaticos unidos por un radical heteroetinileno, y composiciones farmaceuticas y cosmeticas que los contienen.
ATE332728T1 (de)	2006-08-15	Photoempfindliche sonnenschutzmittel
DK1206452T3 (da)	2005-03-14	Fremgangsmåde til fremstilling af benzoperhydro-isoindolforbindelser