DK0994890T3 - Benzimidazolderivater - Google Patents

Benzimidazolderivater

Info

Publication number: DK0994890T3
Authority: DK; Denmark
Prior art keywords: benzimidazole
Prior art date: 1997-06-10

Application number

DK98936306T

Other languages

Danish (da)

English (en)

Inventor

John Charles Drach

Leroy B Townsend

Frank Leslie Boyd Jr

Stanley Dawes Chamberlain

Susan Mary Daluge

David Norman Deaton

Marc W Andersen

George Andrew Freeman

Original Assignee

Univ Michigan

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-10

Filing date

1998-06-08

Publication date

2003-12-01

1997-06-10 Priority claimed from GBGB9711982.0A external-priority patent/GB9711982D0/en

1997-07-11 Priority claimed from GBGB9714552.8A external-priority patent/GB9714552D0/en

1998-06-08 Application filed by Univ Michigan, Glaxo Group Ltd filed Critical Univ Michigan

2003-12-01 Application granted granted Critical

2003-12-01 Publication of DK0994890T3 publication Critical patent/DK0994890T3/da

Links

HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)

DK98936306T 1997-06-10 1998-06-08 Benzimidazolderivater DK0994890T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9711982.0A GB9711982D0 (en)	1997-06-10	1997-06-10	Benzimidazole derivatives
GBGB9714552.8A GB9714552D0 (en)	1997-07-11	1997-07-11	Benzimidazole derivatives
PCT/EP1998/003380 WO1998056761A2 (fr)	1997-06-10	1998-06-08	Derives de benzimidazole

Publications (1)

Publication Number	Publication Date
DK0994890T3 true DK0994890T3 (da)	2003-12-01

Family

ID=26311687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98936306T DK0994890T3 (da)	1997-06-10	1998-06-08	Benzimidazolderivater

Country Status (34)

Country	Link
US (1)	US6455507B1 (fr)
EP (1)	EP0994890B1 (fr)
JP (1)	JP4548866B2 (fr)
KR (1)	KR20010020465A (fr)
CN (1)	CN1265665A (fr)
AP (1)	AP1262A (fr)
AR (1)	AR012964A1 (fr)
AT (1)	ATE246700T1 (fr)
AU (1)	AU740792C (fr)
BR (1)	BR9810745A (fr)
CA (1)	CA2293470C (fr)
CO (1)	CO4970737A1 (fr)
DE (1)	DE69816992T2 (fr)
DK (1)	DK0994890T3 (fr)
EA (1)	EA002305B1 (fr)
EE (1)	EE9900564A (fr)
ES (1)	ES2205527T3 (fr)
HR (1)	HRP980303B1 (fr)
HU (1)	HUP0002224A3 (fr)
ID (1)	ID24054A (fr)
IL (1)	IL133285A0 (fr)
IS (1)	IS5285A (fr)
MA (1)	MA26504A1 (fr)
MY (1)	MY132872A (fr)
NO (1)	NO314847B1 (fr)
NZ (1)	NZ501415A (fr)
OA (1)	OA11230A (fr)
PE (1)	PE84099A1 (fr)
PL (1)	PL337773A1 (fr)
PT (1)	PT994890E (fr)
SK (1)	SK171499A3 (fr)
TR (1)	TR199903053T2 (fr)
TW (1)	TW565566B (fr)
WO (1)	WO1998056761A2 (fr)

Families Citing this family (42)

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WO1997027205A1 (fr)	1996-01-23	1997-07-31	The Regents Of The University Of Michigan	Imidazo[1,2-a]pyridine c-nucleosides comme agents antiviraux
EP1000080A1 (fr)	1997-07-30	2000-05-17	The Regents of The University of Michigan	Benzimidazoles de lyxofuranosyle en tant qu'agents antiviraux
DE19741715A1 (de) *	1997-09-22	1999-03-25	Hoechst Ag	Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung
GB0008939D0 (en) *	2000-04-11	2000-05-31	Glaxo Group Ltd	Process for preparing substituted benzimidazole compounds
ES2291455T3 (es)	2001-03-12	2008-03-01	Avanir Pharmaceuticals	Compuestos de bencimidazol para modular ige e inhibir la proliferacion celular.
WO2004024655A2 (en)	2002-09-12	2004-03-25	Avanir Pharmaceuticals	Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation
TWI276631B (en)	2002-09-12	2007-03-21	Avanir Pharmaceuticals	Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
TW200524951A (en) *	2003-08-01	2005-08-01	Janssen Pharmaceutica Nv	Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides
WO2005049582A1 (fr) *	2003-11-14	2005-06-02	Auspex Pharmaceuticals, Inc.	Procede pour preparer de nouveaux analogues de nucleoside, et leurs utilisations
AU2006216780B8 (en) *	2005-02-22	2010-04-22	The Regents Of The University Of Michigan	Small molecule inhibitors of MDM2 and uses thereof
DE102005019549A1 (de) *	2005-04-25	2006-12-14	Beiersdorf Ag	Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Diaminobenzimidazol
US7989422B2 (en) *	2005-12-22	2011-08-02	Alchemia Limited	Antibacterial agents
US9889156B2 (en)	2006-01-19	2018-02-13	The Regents Of The University Of Michigan	Method for treating noise-induced hearing loss (NIHL)
US9919008B2 (en)	2006-01-19	2018-03-20	The Regents Of The University Of Michigan	Method for treating age-related hearing loss (ARHL)
US8338397B2 (en)	2006-01-19	2012-12-25	The Regents Of The University Of Michigan	Composition and method of treating side effects from antibiotic treatment
USRE46372E1 (en)	2006-01-19	2017-04-25	The Regents Of The Univerity Of Michigan	Method for treating hearing loss
US10238599B2 (en)	2006-01-19	2019-03-26	The Regents Of The University Of Michigan	Composition and method for treating congenital cytomegalovirus induced hearing loss
US8927528B2 (en)	2006-01-19	2015-01-06	The Regents Of The University Of Michigan	Composition for treating hearing loss
US7951845B2 (en)	2006-01-19	2011-05-31	The Regents Of The University Of Michigan	Composition and method of treating hearing loss
US9770433B2 (en)	2006-01-19	2017-09-26	The Regents Of The University Of Michigan	Composition and method for treating tinnitus
WO2009023855A2 (fr)	2007-08-15	2009-02-19	Isis Pharmaceuticals, Inc.	Analogues d'acide nucléique de tétrahydropyrane
US8987468B2 (en) *	2008-02-04	2015-03-24	The Translational Genomics Research Institute	Compounds, pharmaceutical compositions and methods of use of hydroxamic acid derivatives
WO2009100320A2 (fr)	2008-02-07	2009-08-13	Isis Pharmaceuticals, Inc.	Analogues d’acides nucléiques de cyclohexitol bicycliques
CN102361857B (zh)	2008-09-26	2015-09-16	默沙东公司	可用作抗糖尿病剂的环状苯并咪唑衍生物
EP2348857B1 (fr)	2008-10-22	2016-02-24	Merck Sharp & Dohme Corp.	Nouveaux dérivés de benzimidazole cycliques utiles comme agents anti-diabétiques
CN102271511A (zh)	2008-10-29	2011-12-07	默沙东公司	可用作抗糖尿病剂的新颖的环状苯并咪唑衍生物
JP5557845B2 (ja)	2008-10-31	2014-07-23	メルク・シャープ・アンド・ドーム・コーポレーション	糖尿病用剤として有用な新規環状ベンゾイミダゾール誘導体
US20120021515A1 (en)	2009-02-06	2012-01-26	Swayze Eric E	Oligomeric compounds and methods
US8536320B2 (en)	2009-02-06	2013-09-17	Isis Pharmaceuticals, Inc.	Tetrahydropyran nucleic acid analogs
AU2011218830B2 (en)	2010-02-25	2014-07-24	Merck Sharp & Dohme Corp.	Novel cyclic benzimidazole derivatives useful anti-diabetic agents
EP2601204B1 (fr)	2010-04-28	2016-09-07	Ionis Pharmaceuticals, Inc.	Nucléosides modifiés et composés oligomères préparés à partir de ceux-ci
US8546344B2 (en)	2010-10-28	2013-10-01	Viropharma Incorporated	Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl)-1H-benzimidazole
WO2014134493A1 (fr) *	2013-03-01	2014-09-04	Los Alamos National Security, Llc	Composés antibiotiques à large spectre et utilisation de ceux-ci
WO2015168172A1 (fr)	2014-04-28	2015-11-05	Isis Pharmaceuticals, Inc.	Composés oligomères modifiés par liaison
US10077242B2 (en) *	2014-12-01	2018-09-18	Virginia Commonwealth University	Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction
RU2629670C2 (ru) *	2016-08-04	2017-08-31	Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН)	2-Амино-5,6-дифтор-1-(бета-D-рибофуранозил)-бензимидазол, способ получения и противовирусная активность его в отношении вируса герпеса простого 1-го типа
KR102583547B1 (ko)	2020-03-30	2023-10-06	(주)바이오메트릭스 테크놀로지	신규한 벤지미다졸 유도체, 이의 제조방법 및 이의 항암제 용도
EP3907230B1 (fr) *	2020-03-30	2024-08-28	Biometrix Technology Inc.	Nouveaux dérivés de benzimidazole, leur procédé de préparation et leur utilisation comme agent anticancéreux
JP7376108B2 (ja) *	2020-06-23	2023-11-08	バイオメトリックステクノロジーズインコーポレイテッド	新規なベンズイミダゾール誘導体、その製造方法及びその抗癌剤または抗ウイルス剤としての用途
KR102449266B1 (ko)	2020-06-23	2022-09-30	(주)바이오메트릭스 테크놀로지	항암 활성 그리고 항바이러스 활성을 갖는 신규한 벤지미다졸-탄수화물 결합체 화합물(Benzimidazole carbohydrate conjugate compound) 및 이의 제조 방법
KR102342313B1 (ko)	2021-08-27	2021-12-24	(주)바이오메트릭스 테크놀로지	벤지미다졸-탄수화물 결합체 화합물을 포함하는 미셀, 이의 제조방법, 이의 항암제 또는 항바이러스제로서의 용도
CN119119151A (zh) *	2024-09-04	2024-12-13	斯坦德药典标准物质研发(湖北)有限公司	一种马立巴韦的制备方法

Family Cites Families (14)

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Publication number	Priority date	Publication date	Assignee	Title
FR1491244A (fr)	1966-03-09	1967-08-11		Nouveaux benzimidazoles solubles
FR1476350A (fr)	1966-04-18	1967-04-07	Yale & Towne G M B H	Ferme-porte automatique à frein
US3655901A (en)	1970-07-30	1972-04-11	Merck & Co Inc	Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
DE2130030A1 (de)	1971-06-18	1972-12-21	Bayer Ag	Fungizide und bakterizide Mittel
ES482789A0 (es)	1978-08-25	1980-12-01	Thomae Gmbh Dr K	Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
EP0304624A3 (fr)	1987-07-29	1989-03-22	F. Hoffmann-La Roche Ag	Composés de benzimidazol-2-yl-pyridinium
IT1226100B (it)	1988-07-07	1990-12-10	Dompe Farmaceutici Spa	Derivati benzimidazolici farmacologicamente attivi.
US5248672A (en) *	1990-11-01	1993-09-28	The Regents Of The University Of Michigan	Polysubstituted benzimidazole nucleosides as antiviral agents
ZA923641B (en)	1991-05-21	1993-02-24	Iaf Biochem Int	Processes for the diastereoselective synthesis of nucleosides
EP0521463A3 (en) *	1991-07-04	1993-04-14	Hoechst Aktiengesellschaft	Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents
GB9205071D0 (en)	1992-03-09	1992-04-22	Wellcome Found	Therapeutic nucleosides
WO1994008456A1 (fr)	1992-10-21	1994-04-28	The Regents Of The University Of Michigan	Benzimidazoles polysubstitues utilises comme agents antiviraux
US5399580A (en)	1993-03-08	1995-03-21	Burroughs Wellcome Co.	Therapeutic nucleosides-uses
GB9413724D0 (en) *	1994-07-07	1994-08-24	Wellcome Found	Therapeutic nucleosides

1998
- 1998-06-08 PT PT98936306T patent/PT994890E/pt unknown
- 1998-06-08 DK DK98936306T patent/DK0994890T3/da active
- 1998-06-08 BR BR9810745-3A patent/BR9810745A/pt not_active IP Right Cessation
- 1998-06-08 TR TR1999/03053T patent/TR199903053T2/xx unknown
- 1998-06-08 WO PCT/EP1998/003380 patent/WO1998056761A2/fr not_active Ceased
- 1998-06-08 CA CA002293470A patent/CA2293470C/fr not_active Expired - Lifetime
- 1998-06-08 AP APAP/P/1999/001707A patent/AP1262A/en active
- 1998-06-08 IL IL13328598A patent/IL133285A0/xx unknown
- 1998-06-08 EE EEP199900564A patent/EE9900564A/xx unknown
- 1998-06-08 EA EA199901031A patent/EA002305B1/ru not_active IP Right Cessation
- 1998-06-08 EP EP98936306A patent/EP0994890B1/fr not_active Expired - Lifetime
- 1998-06-08 ID IDW20000038A patent/ID24054A/id unknown
- 1998-06-08 CN CN98807910A patent/CN1265665A/zh active Pending
- 1998-06-08 AT AT98936306T patent/ATE246700T1/de not_active IP Right Cessation
- 1998-06-08 ES ES98936306T patent/ES2205527T3/es not_active Expired - Lifetime
- 1998-06-08 SK SK1714-99A patent/SK171499A3/sk unknown
- 1998-06-08 AU AU85360/98A patent/AU740792C/en not_active Ceased
- 1998-06-08 US US09/424,934 patent/US6455507B1/en not_active Expired - Lifetime
- 1998-06-08 NZ NZ501415A patent/NZ501415A/en unknown
- 1998-06-08 HU HU0002224A patent/HUP0002224A3/hu unknown
- 1998-06-08 KR KR1019997011599A patent/KR20010020465A/ko not_active Ceased
- 1998-06-08 JP JP50153899A patent/JP4548866B2/ja not_active Expired - Lifetime
- 1998-06-08 MA MA25102A patent/MA26504A1/fr unknown
- 1998-06-08 PL PL98337773A patent/PL337773A1/xx unknown
- 1998-06-08 DE DE69816992T patent/DE69816992T2/de not_active Expired - Lifetime
- 1998-06-09 PE PE1998000488A patent/PE84099A1/es not_active Application Discontinuation
- 1998-06-09 TW TW087109162A patent/TW565566B/zh not_active IP Right Cessation
- 1998-06-09 MY MYPI98002560A patent/MY132872A/en unknown
- 1998-06-09 CO CO98032828A patent/CO4970737A1/es unknown
- 1998-06-09 HR HR980303A patent/HRP980303B1/xx not_active IP Right Cessation
- 1998-06-10 AR ARP980102756A patent/AR012964A1/es not_active Application Discontinuation
1999
- 1999-12-06 IS IS5285A patent/IS5285A/is unknown
- 1999-12-09 OA OA9900275A patent/OA11230A/en unknown
- 1999-12-09 NO NO19996086A patent/NO314847B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU8536098A (en)	1998-12-30
WO1998056761A2 (fr)	1998-12-17
HRP980303B1 (en)	2002-08-31
EP0994890A2 (fr)	2000-04-26
PL337773A1 (en)	2000-09-11
EA199901031A1 (ru)	2000-06-26
BR9810745A (pt)	2001-03-13
OA11230A (en)	2003-07-09
NZ501415A (en)	2001-10-26
HK1024921A1 (en)	2000-10-27
TR199903053T2 (xx)	2000-11-21
HUP0002224A1 (hu)	2001-04-28
IS5285A (is)	1999-12-06
US20020094963A1 (en)	2002-07-18
DE69816992D1 (en)	2003-09-11
HUP0002224A3 (en)	2003-05-28
JP4548866B2 (ja)	2010-09-22
KR20010020465A (ko)	2001-03-15
AP9901707A0 (en)	1999-12-31
US6455507B1 (en)	2002-09-24
EA002305B1 (ru)	2002-02-28
CA2293470C (fr)	2008-05-13
IL133285A0 (en)	2001-04-30
CA2293470A1 (fr)	1998-12-17
AU740792B2 (en)	2001-11-15
NO996086D0 (no)	1999-12-09
EE9900564A (et)	2000-06-15
AR012964A1 (es)	2000-11-22
SK171499A3 (en)	2000-08-14
MA26504A1 (fr)	2004-12-20
JP2002504105A (ja)	2002-02-05
ATE246700T1 (de)	2003-08-15
CN1265665A (zh)	2000-09-06
WO1998056761A3 (fr)	1999-04-15
AP1262A (en)	2004-03-16
PE84099A1 (es)	1999-09-24
PT994890E (pt)	2003-11-28
HRP980303A2 (en)	1999-04-30
DE69816992T2 (de)	2004-07-22
NO996086L (no)	2000-02-09
TW565566B (en)	2003-12-11
EP0994890B1 (fr)	2003-08-06
CO4970737A1 (es)	2000-11-07
ES2205527T3 (es)	2004-05-01
AU740792C (en)	2003-01-23
ID24054A (id)	2000-07-06
MY132872A (en)	2007-10-31
NO314847B1 (no)	2003-06-02

Publication	Publication Date	Title
NO996086D0 (no)	1999-12-09	Benzimidazolderivater
DE69802795D1 (de)	2002-01-17	Präsentiervorrichtung
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