DK1012256T3 - Rekombinante fusionsproteiner på basis af ribosom-inaktiverende proteiner fra misteltenen Viscum album - Google Patents

Rekombinante fusionsproteiner på basis af ribosom-inaktiverende proteiner fra misteltenen Viscum album

Info

Publication number
DK1012256T3
DK1012256T3 DK98905267T DK98905267T DK1012256T3 DK 1012256 T3 DK1012256 T3 DK 1012256T3 DK 98905267 T DK98905267 T DK 98905267T DK 98905267 T DK98905267 T DK 98905267T DK 1012256 T3 DK1012256 T3 DK 1012256T3
Authority
DK
Denmark
Prior art keywords
fusion proteins
module
ribosome
nucleic acid
acid molecules
Prior art date
Application number
DK98905267T
Other languages
Danish (da)
English (en)
Inventor
Juergen Eck
Arno Schmidt
Holger Zinke
Original Assignee
Viscum Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viscum Ag filed Critical Viscum Ag
Application granted granted Critical
Publication of DK1012256T3 publication Critical patent/DK1012256T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK98905267T 1997-01-02 1998-01-02 Rekombinante fusionsproteiner på basis af ribosom-inaktiverende proteiner fra misteltenen Viscum album DK1012256T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97100012 1997-01-02

Publications (1)

Publication Number Publication Date
DK1012256T3 true DK1012256T3 (da) 2004-07-12

Family

ID=8226349

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98905267T DK1012256T3 (da) 1997-01-02 1998-01-02 Rekombinante fusionsproteiner på basis af ribosom-inaktiverende proteiner fra misteltenen Viscum album

Country Status (10)

Country Link
US (2) US20020045208A1 (fr)
EP (1) EP1012256B1 (fr)
AT (1) ATE263248T1 (fr)
AU (1) AU6092498A (fr)
CA (1) CA2276534C (fr)
DE (2) DE59811111D1 (fr)
DK (1) DK1012256T3 (fr)
ES (1) ES2216269T3 (fr)
PT (1) PT1012256E (fr)
WO (1) WO1998029540A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19804210A1 (de) * 1998-02-03 1999-08-12 Biosyn Arzneimittel Gmbh Rekombinante Mistellektine
KR20010011330A (ko) * 1999-07-27 2001-02-15 김종배 한국산 겨우살이 추출물과 이로부터 분리한 단백질 및 상기 단백질에서 분리한 렉틴
ATE372130T1 (de) * 2000-04-22 2007-09-15 Pharmedartis Gmbh Apoptotika
US7273722B2 (en) * 2000-11-29 2007-09-25 Allergan, Inc. Neurotoxins with enhanced target specificity
DK1418800T3 (da) 2001-07-09 2007-09-24 Univ Copenhagen Metoder og stiklinger til massedyrkning af planteparasitter
DE10149030A1 (de) * 2001-10-05 2003-04-10 Viscum Ag Stabile galenische gefriergetrocknete Arzneimittelzubereitung von rViscumin
DE102011003478A1 (de) 2011-02-01 2012-08-02 Cytavis Biopharma Gmbh Antivirales Mittel enthaltend rekombinante Mistellektine
SG11201408287RA (en) * 2012-06-26 2015-01-29 Biovalence Sdn Bhd Rapid specific pathogen free animal

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894443A (en) * 1984-02-08 1990-01-16 Cetus Corporation Toxin conjugates
DE4221836A1 (de) * 1992-07-03 1994-01-05 Gabius Hans Joachim Prof Dr Das biochemisch aufgereinigte Mistel-Lektin (ML-1) als therapeutisch anwendbarer Immunmodulator
ES2124470T3 (es) * 1995-06-26 1999-02-01 Madaus Ag Koeln Lectina recombinante de muerdago.
AU5003597A (en) * 1996-10-28 1998-05-22 Medical University Of South Carolina Methods and compositions for ricin fusion protein immunotoxins to treat cancer and autoimmune disease

Also Published As

Publication number Publication date
AU6092498A (en) 1998-07-31
CA2276534A1 (fr) 1998-07-09
CA2276534C (fr) 2011-11-22
ATE263248T1 (de) 2004-04-15
EP1012256A2 (fr) 2000-06-28
DE19880004D2 (de) 2000-06-15
WO1998029540A3 (fr) 1998-11-12
US20020045208A1 (en) 2002-04-18
US20080227157A1 (en) 2008-09-18
DE59811111D1 (de) 2004-05-06
WO1998029540A2 (fr) 1998-07-09
EP1012256B1 (fr) 2004-03-31
ES2216269T3 (es) 2004-10-16
PT1012256E (pt) 2004-08-31

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