DK1015026T3 - IL-12 som en adjuvans til Bordetella pertussis-vacciner - Google Patents

IL-12 som en adjuvans til Bordetella pertussis-vacciner

Info

Publication number: DK1015026T3
Authority: DK; Denmark
Prior art keywords: adjuvant; bordetella pertussis; pertussis vaccines; vaccines; bordetella
Prior art date: 1996-05-31

Application number

DK97932137T

Other languages

Danish (da)

English (en)

Inventor

Kingston H G Mills

Bernard P Mahon

Mark S Ryan

Fiona Griffin

Original Assignee

Nat Univ Ireland Maynooth

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-31

Filing date

1997-05-30

Publication date

2006-09-11

1997-05-30 Application filed by Nat Univ Ireland Maynooth filed Critical Nat Univ Ireland Maynooth

2006-09-11 Application granted granted Critical

2006-09-11 Publication of DK1015026T3 publication Critical patent/DK1015026T3/da

Links

102000013462 Interleukin-12 Human genes 0.000 title abstract 2
108010065805 Interleukin-12 Proteins 0.000 title abstract 2
239000002671 adjuvant Substances 0.000 title abstract 2
241000588832 Bordetella pertussis Species 0.000 title 1
229940066827 pertussis vaccine Drugs 0.000 title 1
241000588807 Bordetella Species 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
229940117681 interleukin-12 Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/208—IL-12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Mycology (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Gastroenterology & Hepatology (AREA)
Microbiology (AREA)
Zoology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK97932137T 1996-05-31 1997-05-30 IL-12 som en adjuvans til Bordetella pertussis-vacciner DK1015026T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1587196P	1996-05-31	1996-05-31
US82986597A	1997-03-31	1997-03-31

Publications (1)

Publication Number	Publication Date
DK1015026T3 true DK1015026T3 (da)	2006-09-11

Family

ID=26687907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97932137T DK1015026T3 (da)	1996-05-31	1997-05-30	IL-12 som en adjuvans til Bordetella pertussis-vacciner

Country Status (10)

Country	Link
US (5)	US6929794B1 (de)
EP (2)	EP1015026B1 (de)
JP (2)	JP3737519B2 (de)
AT (1)	ATE325621T1 (de)
AU (1)	AU724743B2 (de)
DE (1)	DE69735856T2 (de)
DK (1)	DK1015026T3 (de)
ES (1)	ES2262181T3 (de)
PT (1)	PT1015026E (de)
WO (1)	WO1997045139A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE325621T1 (de) *	1996-05-31	2006-06-15	Nat Univ Ireland Maynooth	Il-12 als adjuvanz für bordetella pertussis impfstoffe
EP1053015A2 (de) *	1998-02-12	2000-11-22	American Cyanamid Company	Mit interleukin-12 formulierten pneumokokkus und meningokokkus impfstoffen
US6303114B1 (en)	1998-03-05	2001-10-16	The Medical College Of Ohio	IL-12 enhancement of immune responses to T-independent antigens
US5985264A (en) *	1998-03-05	1999-11-16	The Medical College Of Ohio	IL-12 Stimulation of Neonatal immunity
AU747917B2 (en) *	1998-03-05	2002-05-30	Medical College Of Ohio, The	Enhancement of immunity by intranasal inoculation of IL-12
US7611721B1 (en)	1999-05-13	2009-11-03	Wyeth Holdings Corporation	Adjuvant combination formulations
AUPQ761200A0 (en) *	2000-05-19	2000-06-15	Hunter Immunology Limited	Compositions and methods for treatment of mucosal infections
CN1437481A (zh) *	2000-06-22	2003-08-20	美国氰胺公司	作为佐剂组合的qs－21和il－12
PE20020530A1 (es) *	2000-11-10	2002-06-18	Wyeth Corp	Formulaciones de combinacion adyuvante
AUPR381601A0 (en) *	2001-03-19	2001-04-12	Monash University	Method of treating respiratory conditions
US20030129161A1 (en) *	2001-09-17	2003-07-10	Hsien-Jue Chu	Interleukin-12 as a veterinary vaccine adjuvant
US20080138833A1 (en) *	2006-12-07	2008-06-12	Wyeth	Methods and compositions for assessing il-12 or the neutralization of il-12 in a sample
ES2331271B1 (es) *	2007-06-29	2010-10-14	Universidad Del Pais Vasco	Metodo para la internalizacion de bacterias no invasivas en celulas eucariotas.
PT2670432T (pt) *	2011-02-04	2021-05-04	Zoetis Services Llc	Composições imunogénicas de bordetella bronchiseptica
US12605349B2 (en)	2024-09-05	2026-04-21	Orbus Therapeutics, Inc.	Methods of treating grade 3 astrocytoma

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4518584A (en)	1983-04-15	1985-05-21	Cetus Corporation	Human recombinant interleukin-2 muteins
CA1340373C (en) *	1986-01-28	1999-02-02	Rino Rappuoli	Cloning and sequencing of the dna fragment which codes for the five subunits of the pertussis toxin, a hybrid plasmid containing the dna fragment and micro-organisms transformed by the hybrid plasmid and capable of expressing all or some of the subunits of the pertussis toxin
US4705686A (en) *	1986-05-09	1987-11-10	American Cyanamid	Process for the preparation of acellular Bordetalla pertussis vaccine
JPH01193231A (ja) *	1988-01-27	1989-08-03	Takeda Chem Ind Ltd	抗腫瘍剤
ATE140483T1 (de)	1988-11-10	1996-08-15	Genetics Inst	Natürlicher killerzellen-stimulationsfaktor
US5162223A (en) *	1989-02-17	1992-11-10	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Resources	Hybridomas and resulting monoclonal antibodies directed against antigens of Bordetella pertussis
AU648509B2 (en) *	1989-07-14	1994-04-28	Wyeth Holdings Corporation	Stable vaccine compositions containing interleukins
GB9007657D0 (en) *	1990-04-04	1990-05-30	Connaught Lab	Purification of a pertussis outer membrane protein(omp69)
US5904920A (en)	1991-10-04	1999-05-18	Whitehead Institute For Biomedical Research	Regulation of systemic immune responses utilizing cytokines and antigens
EP0653943A4 (de)	1992-07-13	1996-10-02	Baylor College Medicine	Eine somatische gentherapie auf gelenke zielend.
US5571515A (en) *	1994-04-18	1996-11-05	The Wistar Institute Of Anatomy & Biology	Compositions and methods for use of IL-12 as an adjuvant
DE69529219T2 (de)	1994-07-01	2003-11-06	Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville	Helicobacter proteine und impstoffe
AU3735095A (en)	1994-09-30	1996-04-26	Ludwig Institute For Cancer Research	Compositions containing a p53 derived protein or peptide, an adjuvant, and interleukin-12 and uses thereof
JP3939752B2 (ja) *	1994-10-05	2007-07-04	バンダービルトユニバーシティー	パラミクソウイルスワクチン用アジュバントとしてのインターロイキン−１２
WO1997000321A1 (en)	1995-06-14	1997-01-03	Commonwealth Scientific And Industrial Research Organisation	Immune response modulators and uses therefor
ATE325621T1 (de) *	1996-05-31	2006-06-15	Nat Univ Ireland Maynooth	Il-12 als adjuvanz für bordetella pertussis impfstoffe

1997
- 1997-05-30 AT AT97932137T patent/ATE325621T1/de not_active IP Right Cessation
- 1997-05-30 JP JP54278597A patent/JP3737519B2/ja not_active Expired - Fee Related
- 1997-05-30 DK DK97932137T patent/DK1015026T3/da active
- 1997-05-30 EP EP97932137A patent/EP1015026B1/de not_active Expired - Lifetime
- 1997-05-30 EP EP05017305A patent/EP1649868A1/de not_active Withdrawn
- 1997-05-30 AU AU35670/97A patent/AU724743B2/en not_active Ceased
- 1997-05-30 PT PT97932137T patent/PT1015026E/pt unknown
- 1997-05-30 ES ES97932137T patent/ES2262181T3/es not_active Expired - Lifetime
- 1997-05-30 WO PCT/US1997/008802 patent/WO1997045139A2/en not_active Ceased
- 1997-05-30 DE DE69735856T patent/DE69735856T2/de not_active Expired - Fee Related
1998
- 1998-10-29 US US09/182,824 patent/US6929794B1/en not_active Expired - Fee Related
2005
- 2005-01-18 JP JP2005010651A patent/JP2005112865A/ja active Pending
- 2005-03-04 US US11/071,352 patent/US20050158276A1/en not_active Abandoned
2006
- 2006-07-27 US US11/493,540 patent/US20060263380A1/en not_active Abandoned
- 2006-07-27 US US11/493,512 patent/US20060257419A1/en not_active Abandoned
- 2006-07-27 US US11/493,532 patent/US20060263379A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU724743B2 (en)	2000-09-28
ATE325621T1 (de)	2006-06-15
EP1649868A1 (de)	2006-04-26
DE69735856T2 (de)	2006-11-16
WO1997045139A2 (en)	1997-12-04
US20060263379A1 (en)	2006-11-23
US20050158276A1 (en)	2005-07-21
PT1015026E (pt)	2006-08-31
DE69735856D1 (de)	2006-06-14
JP2001527516A (ja)	2001-12-25
ES2262181T3 (es)	2006-11-16
JP2005112865A (ja)	2005-04-28
US6929794B1 (en)	2005-08-16
US20060263380A1 (en)	2006-11-23
JP3737519B2 (ja)	2006-01-18
AU3567097A (en)	1998-01-05
WO1997045139A3 (en)	1998-02-12
EP1015026A2 (de)	2000-07-05
US20060257419A1 (en)	2006-11-16
EP1015026B1 (de)	2006-05-10

Publication	Publication Date	Title
DE69735856D1 (de)	2006-06-14	Il-12 als adjuvanz für bordetella pertussis impfstoffe
ITRM930316A0 (it)	1993-05-14	Dina radiografico-chirurgica orientabile per ipianti nelle ossa mascellari.
KR950702125A (ko)	1995-06-19	보조약을 함유하는 백신 조성물(vaccine composition containing adjuvants)
NL300403I1 (en)	2009-10-01	Method and manufacture of an acellular vaccine comprising Bordetella pertussis antigens
FI955667A7 (fi)	1996-01-12	Adjuvantteja RS-viruksen vastaisia rokotteita varten
NO912713D0 (no)	1991-07-10	Effektive vaksiner mot bordetella pertussis omfattende enkombinasjon av individuelt rensete pertussis-antigener.
DK0745387T3 (da)	2005-02-21	Adjuvanser til virale vacciner
DK0745388T3 (da)	2002-12-02	Mammalt vaccinepræparat omfattende squalen eller squalan, phospholipid og et overfladeaktivt stof som adjuvans
NO892997D0 (no)	1989-07-21	Bordetella pertussis vaksine.
ES2097618T3 (es)	1997-04-01	Formulacion de aerosol a base de fusafungina.
ITMI910371U1 (it)	1992-10-30	Canaletta ecologica per la risagomatura di fossi, o similari, e per la correzione della pendenza di questi ultimi
DE69128095D1 (de)	1997-12-04	Azelluläre impfstoffe